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公开(公告)号：KR101457442B1
公开(公告)日：2014-11-10
申请号：KR1020120121346
申请日：2012-10-30
Applicant: 한국식품연구원
IPC: A61K31/685 , A61P11/06 , A61P1/04
CPC classification number: A61K31/575 , A23L33/105 , A23V2002/00 , A61K9/4866 , A61K36/88 , A23V2200/314 , A23V2200/32 , A23V2200/322 , A23V2250/21
Abstract: 본 발명은 감마오리자놀의 히스타민 수용체 길항제로서의 신규 용도를 제공한다. 감마오리자놀은 천연 항히스타민제로 사용되어, 알레르기성 비염; 염증성 장질환; 천식; 기관지염; 구토; 위 및 십이지장 궤양; 위식도 역류; 수면장애; 불안; 및 우울증의 예방 또는 치료에 이용될 수 있음은 물론 향상된 입면시간의 감소, 수면시간의 증가 및 논렘수면 시간의 증가 효과가 있다. 감마오리자놀은 쌀겨에서 유래되는 천연물로서 장기간 사용하여도 인지장애(cognitive impairment), 내성 또는 의존성이 형성되는 부작용이 없다.
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公开(公告)号：KR1020140118971A
公开(公告)日：2014-10-08
申请号：KR1020140122634
申请日：2014-09-16
Applicant: 한국식품연구원
IPC: A61K31/685 , A61P25/20
CPC classification number: A61K31/215 , A23L33/10 , A23L33/105 , A23V2002/00 , A23V2200/322 , A23V2250/21 , A61K36/899
Abstract: The present invention provides a novel use as histamine receptor antagonists of gamma-oryzanol. The gamma-oryzanol is used as a natural anti-histamine agent, thereby can be used for preventing or treating allergic rhinitis, inflammatory bowel disease, asthma, bronchitis, vomiting, stomach and duodenal ulcers, gastroesophageal reflux, sleep disorders, anxiety, and depression; and have effects of reducing a hypnagogue time, increasing a sleep time, and increasing a non-REM sleep time. The gamma-oryzanol is a natural product derived from rice bran which has no side effects such as cognitive impairment, tolerance, or dependence even for a long-term use.
Abstract translation: 本发明提供作为γ-谷维素的组胺受体拮抗剂的新用途。 γ-谷维素被用作天然的抗组胺药物，从而可用于预防或治疗过敏性鼻炎，炎症性肠病，哮喘，支气管炎，呕吐，胃和十二指肠溃疡，胃食管反流，睡眠障碍，焦虑和抑郁 ; 并具有减少嗜睡时间，增加睡眠时间以及增加非REM睡眠时间的效果。 γ-谷维素是来自米糠的天然产物，即使对于长期使用也没有副作用，例如认知障碍，耐受性或依赖性。
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公开(公告)号：KR1020140056654A
公开(公告)日：2014-05-12
申请号：KR1020120121346
申请日：2012-10-30
Applicant: 한국식품연구원
IPC: A61K31/685 , A61P11/06 , A61P1/04
CPC classification number: A61K31/575 , A23L33/105 , A23V2002/00 , A61K9/4866 , A61K36/88 , A23V2200/314 , A23V2200/32 , A23V2200/322 , A23V2250/21
Abstract: The present invention provides new uses of gamma-oryzanol as a histamine receptor antagonist. The gamma-oryzanol is used as a natural anti-histamine agent which can be used for preventing or treating allergic rhinitis; inflammatory bowel disease; asthma; bronchitis; vomiting; stomach and duodenal ulcers; gastro-oesophageal reflux; sleep disorders; anxiety; and depression, and has an effect for reducing an increased hypnagogue time and increasing a sleep time. The gamma-oryzanol is a natural product derived from rice bran, thereby has no side effects, which develop cognitive impairment, tolerance, or dependence, even for a long-term use.
Abstract translation: 本发明提供γ-谷维素作为组胺受体拮抗剂的新用途。 γ-谷维素用作天然抗组胺药物，可用于预防或治疗过敏性鼻炎; 炎症性肠病; 哮喘; 支气管炎; 呕吐; 胃和十二指肠溃疡; 胃食管反流; 睡眠障碍 焦虑; 和抑郁症，并且具有减少增加的嗜热时间时间和增加睡眠时间的作用。 γ-谷维素是衍生自米糠的天然产物，因此没有副作用，即使长期使用也会产生认知障碍，耐受性或依赖性。
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公开(公告)号：KR101303713B1
公开(公告)日：2013-09-04
申请号：KR1020110039353
申请日：2011-04-27
Applicant: 한국식품연구원
IPC: A61K36/27 , A61K36/287 , A61K36/14 , A61P25/20
Abstract: 본 발명은 백하수오(
Cynanchum wilfordii ), 구절초(
Chrysanthemum zawadskii ) 또는 측백엽(
Thuja orientalis ) 추출물을 포함하는 수면장애 예방 또는 치료용 조성물에 관한 것이다. 백하수오 추출물, 구절초 추출물 및 측백엽 추출물로 구성된 군으로부터 선택되는 최소 하나의 천연 추출물 또는 그의 용매 분획(fraction)을 유효성분으로 포함하는 수면 장애의 예방 또는 치료용 약제학적 조성물을 제공한다. 본 발명의 조성물은 종래 수면유도제로 사용되는 의약인 디아제팜과 거의 동일한 수준 또는 향상된 입면시간의 감소 및 수면시간의 증가 효과가 있다. 또한 천연물인 백하수오, 구절초 또는 측백엽로부터 추출한 것으로서 장기간 사용하여도 인지장애(cognitive impairment), 내성 또는 의존성이 형성되는 부작용이 없다.-
25.发明公开갈조류 추출물을 포함하는 가바 Ａ형－벤조다이아제핀 수용체 활성용 조성물 및 불안 완화, 경련 개선, 진정 작용, 및 수면 유도 및 개선용 조성물 无效用于引发GABAA-苯并二氮杂受体的组合物和具有抗炎，抗肿瘤，抗痛苦和缓解改善包含褐色海藻提取物的作用的组合物
公开(公告)号：KR1020130020701A
公开(公告)日：2013-02-27
申请号：KR1020130002539
申请日：2013-01-09
Applicant: 한국식품연구원
Abstract: PURPOSE: A composition containing a brown algae extract for activating a GABA A-benzodiazepine receptor is provided to ensure affinity to the receptor and to treat anxiety and insomnia without side effects. CONSTITUTION: A pharmaceutical composition for anti-anxiety, anti-convulsant, or insomnia treatment, which activates a GABA A-benzodiazepine receptor contains an extract of brown algae, except for Ecklonia cava, Dictyopteris prolifera Okamura, Dictyota dichotoma Lamouroux, Sargassum horneri C.Agardh, Sargassum patens C. Agardh, and Ishige okamurae Yendo. The brown algae extract is a water extract, an ethanol extract, and a methanol extract.
Abstract translation: 目的：提供含有用于活化GABA的苯甲二氮类受体的棕色藻类提取物的组合物，以确保对受体的亲和力，并且治疗焦虑和失眠而没有副作用。 构成：用于抗焦虑，抗惊厥或失眠治疗的药物组合物，其激活GABA-苯并二氮杂受体，其含有褐藻类提取物，除了Ecklonia cava，Dictyopteris prolifera Okamura，Dictyota dichotoma Lamouroux，Sargassum horneri C. Agardh，Sargassum patens C. Agardh和Ishige okamurae Yendo。 褐藻提取物是水提取物，乙醇提取物和甲醇提取物。
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Patent Agency Ranking
公开(公告)号：KR1020120132652A
公开(公告)日：2012-12-07
申请号：KR1020110050472
申请日：2011-05-27
Applicant: 한국식품연구원
IPC: A61K36/899 , A61P25/24 , A61P25/20 , A61P25/00
CPC classification number: A61K36/899 , A61K2236/13
Abstract: PURPOSE: A rice extract for preventing, relieving, or treating sleep disorder, anxiety, or depression is provided to reduce sleep latency and to enhance non-REM sleep and sleeping time without side effects. CONSTITUTION: A pharmaceutical composition for preventing or treating sleep disorder, anxiety, or depression contains rice extract as an active ingredient. The rice extract is prepared using water, an organic solvent, or a mixture thereof. The organic solvent includes low carbon number alcohol, hexane, acetone, ethyl acetate, chloroform, or diethyl ether. The rice extract is a low carbon number alcohol extract, an ethanol extract, a hexane extract, or a fraction. A food composition for preventing or treating sleep disorder, anxiety, or depression contains the rice extract as an active ingredient. An anti-histaminic agent contains the rice extract as an active ingredient.
Abstract translation: 目的：提供用于预防，缓解或治疗睡眠障碍，焦虑或抑郁症的水稻提取物以减少睡眠潜伏期并增加非REM睡眠和睡眠时间而没有副作用。 构成：用于预防或治疗睡眠障碍，焦虑或抑郁症的药物组合物含有水稻提取物作为活性成分。 水提取物是使用水，有机溶剂或其混合物制备的。 有机溶剂包括低碳数醇，己烷，丙酮，乙酸乙酯，氯仿或二乙醚。 米提取物是低碳数醇提取物，乙醇提取物，己烷提取物或级分。 用于预防或治疗睡眠障碍，焦虑或抑郁症的食物组合物含有米提取物作为活性成分。 抗组胺剂含有米提取物作为活性成分。
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公开(公告)号：KR1020120063563A
公开(公告)日：2012-06-18
申请号：KR1020100123983
申请日：2010-12-07
Applicant: 한국식품연구원
CPC classification number: A23L17/70 , A23L5/11 , A23L7/157 , A23V2002/00 , A23V2200/14
Abstract: PURPOSE: A producing method of fried fish paste containing rice powder and glutinous rice powder paste is provided to offer the chewy texture to the fish paste. CONSTITUTION: A producing method of fried fish paste containing rice powder and glutinous rice powder paste comprises the following steps: thawing frozen surimi, and grinding the surimi before mixing with edible salt; mixing the surimi mixture with glutinous rice powder, non-glutinous rice powder, or their mixture in a paste form; adding soybean protein, sugar, egg white, and xylose into the mixture to obtain final mixture; molding the final mixture into the fixed shape, and firstly frying the mixture using 140-160 deg C soybean oil for 2-4 minutes; cooling the firstly fried product for 2-4 minutes, and secondly frying the obtained product using the using 140-160 deg C soybean oil for 2-4 minutes; and vacuum packaging the obtained fried fish paste after removing the oil and cooling.
Abstract translation: 目的：提供含有米粉和糯米粉糊的油炸鱼酱的生产方法，为鱼酱提供耐嚼纹理。 构成：含有米粉和糯米粉的油炸鱼酱的生产方法包括以下步骤：解冻冷冻鱼糜，并与食盐混合前研磨鱼糜; 将糜米混合物与糯米粉，非糯米粉或其混合物以糊状混合; 将大豆蛋白，糖，蛋清和木糖加入到混合物中以获得最终混合物; 将最终混合物成型为固定形状，首先使用140-160摄氏度的大豆油将混合物煎炸2-4分钟; 冷却第一个油炸产品2-4分钟，然后使用140-160摄氏度大豆油煎煮所得产品2-4分钟; 并真空包装后取出油炸鱼酱去油后冷却。
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公开(公告)号：KR102262759B1
公开(公告)日：2021-06-10
申请号：KR1020190130750
申请日：2019-10-21
Applicant: 한국식품연구원
IPC: A61K36/9066 , A61P43/00 , A23L33/105
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公开(公告)号：KR1020210047416A
公开(公告)日：2021-04-30
申请号：KR1020190130751
申请日：2019-10-21
Applicant: 한국식품연구원
IPC: A61K36/9066 , A61K36/488 , A61K36/899 , A61P25/20 , A23L33/105 , A23K10/30
Abstract: 본발명은강황추출물, 및칡 추출물또는쌀겨추출물을유효성분으로함유하는수면장애의예방, 개선또는치료용조성물에관한것이다. 본발명의강황추출물; 및칡 추출물또는쌀겨추출물의복합물은종래수면유도제로사용되는의약과거의동일한수준또는향상된수준으로수면지속시간의증가효과를제공한다. 또한, 천연물인강황; 및칡 또는쌀겨로부터유래한것이어서장기간사용하여도인지장애(cognitive impairment), 내성또는의존성이형성되는부작용이없다. 따라서, 본발명의강황추출물; 및칡 추출물또는쌀겨추출물을유효성분으로포함하는수면장애예방, 개선또는치료용조성물은경쟁력있는식품조성물및 의약조성물의제조에매우유용하다.
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公开(公告)号：KR102241762B1
公开(公告)日：2021-04-19
申请号：KR1020200048012
申请日：2020-04-21
Applicant: 한국식품연구원
IPC: A23L33/105 , A61K36/03 , A61P25/24 , A23K10/30
Abstract: 본발명에따른넓패추출물을유효성분으로함유하는조성물은천연약재를이용하여스트레스를완화시키고, 스트레스로인해발생되는우울증을예방하거나부작용없이효율적으로개선할수 있다.
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