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    25.
    发明专利
    未知

    公开(公告)号：DE4117904A1

    公开(公告)日：1992-12-03

    申请号：DE4117904

    申请日：1991-05-31

    Applicant: BASF AG

    Inventor： LUBISCH WILFRIED DR ,  SCHULT SABINE DR ,  BEHL BERTHOLD DR ,  KIRCHENGAST MICHAEL DR

    IPC: C07D211/26 ,  C07D211/56 ,  C07D211/58 ,  C07D401/04

    Abstract: Substituted N-phenylpiperidines I (* CHEMICAL STRUCTURE *) I (R1=H, NO2, CN, halogen, C1-C4-alkyl, CF3, OCF3, OH, CH2OH, COOH, CHO, NH-CHO, NH2, CO-NH2, 5-tetrazinyl, R4-O-, R4-O-CH2-, R4O-CO-, R4-CO-, R4-NH-CO, R4-CO-NH-, R4-SO2-NH-; R2=H, NO2, halogen, C1-C4-alkyl or R4-O-; (* CHEMICAL STRUCTURE *) (* CHEMICAL STRUCTURE *) (* CHEMICAL STRUCTURE *) (* CHEMICAL STRUCTURE *) (* CHEMICAL STRUCTURE *) R4=C1-C4-alkyl or phenyl which can carry one of the R2 radicals; R5, R6=H or one of the R4 radicals; R7 =one of the R1 radicals; n=0 or 1; m=1 or 2; with the proviso that R3 is (* CHEMICAL STRUCTURE *) only when n is 1, and the optical isomers in the case of optical isomerism, and the physiologically tolerated acid addition salts, are suitable as drugs.

    26.
    发明专利
    未知

    公开(公告)号：DE59309070D1

    公开(公告)日：1998-11-26

    申请号：DE59309070

    申请日：1993-05-17

    Applicant: BASF AG

    Inventor： LUBISCH WILFRIED DR ,  BEHL BERTHOLD DR ,  HOFMANN HANS PETER DR

    IPC: A61K31/495 ,  A61K31/498 ,  A61P25/00 ,  A61P25/08 ,  A61P25/20 ,  A61P25/22 ,  A61P25/24 ,  A61P25/26 ,  C07D241/44 ,  C07D241/52 ,  C07D401/04 ,  C07D403/04 ,  C07D487/12 ,  C07D487/14

    Abstract: Quinoxaline-2,3-(1H,4H)diones of the general formula I in which the variables have the following meaning: R is hydrogen; an aliphatic radical having up to 12 C atoms, which can carry one of the following substituents: phenyl, cyclopentyl, cyclohexyl or a group -CO-R , -CO-O-R or -CO-NH-R , where R denotes hydrogen, C1-C4-alkyl, phenyl, benzyl or 1-phenylethyl; a cycloaliphatic radical having up to 12 C atoms, or a phenyl group, where the cyclic groups contained in R can carry up to three of the following substituents: C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy, C1-C4-haloalkoxy, halogen, nitro, cyano, -CO-O-R and -CO-NH-R ; R is a pyrrol-1-yl group which can carry up to two of the following substituents: C1-C4-alkyl, phenyl, phenylsulphonyl, nitro, cyano and one of the groups -CO-O-R , -CO-NH-R , -CH2-O-R , -O-R and -CH=NO-R ; R is identical or different radicals from the following: C1-C4-alkyl, C1-C4-alkoxy, trifluoromethyl, trichloromethyl, trifluoromethoxy, trichloromethoxy, fluorine, chlorine, bromine, iodine, nitro, cyano and one of the groups -CO-O-R and -CO-NH-R and a fused benzene ring; n is 0 to 3. Quinoxaline-2,3-(1H,4H)diones I' in which R has the meaning mentioned. The compounds I and I' are suitable as medicines for human and veterinary medicine.

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