公开(公告)号：CZ284463B6

公开(公告)日：1998-12-16

申请号：CZ278593

申请日：1993-12-16

Applicant: BASF AG

Inventor： STEINER GERD DR ,  UNGER LILIANE DR ,  BEHL BERTHOLD DR ,  TESCHENDORF HANS-JUERGEN DR

IPC: C07D209/02 ,  A61K31/40

Abstract: N-substd. 3-azabicyclo(3.2.0)heptane derivs. of formula (I) and their acid addn. salts are new. In (I), R1 = phenyl, thienyl or pyrrole, all opt. substd. by halo, OMe, OH, amino or NO2; R2 is H or phenyl (opt. substd. by halo); n = 1-4; A = H, CH=CH2, NR6-CO-Ar or C(R3)(R4)Ar; Ar = phenyl substd. by R5; R3 = H, OH or phenyl (opt. substd. by F, Cl or Br); R4 = H; or R3+R4 = O; R5 = H, F, Cl or Br; and R6 = H or Me.

公开(公告)号：CZ9302785A3

公开(公告)日：1995-07-12

申请号：CZ278593

申请日：1993-12-16

Applicant: BASF AG

Inventor： STEINER GERD DR ,  UNGER LILIANE DR ,  BEHL BERTHOLD DR ,  TESCHENDORF HANS-JUERGEN DR

IPC: C07D209/02 ,  A61K31/40

公开(公告)号：CZ9403237A3

公开(公告)日：1995-05-17

申请号：CZ323794

申请日：1993-06-08

Applicant: BASF AG

Inventor： STEINER GERD DR ,  UNGER LILIANE DR ,  BEHL BERTHOLD DR ,  TESCHENDORF HANS-JUERGEN DR ,  MUNSCHAUER RAINER DR

IPC: C07D513/04 ,  A61K20060101 ,  A61K31/33 ,  A61K31/395 ,  A61K31/40 ,  A61K31/4045 ,  A61K31/4184 ,  A61K31/505 ,  A61K31/506 ,  A61K31/513 ,  A61K31/517 ,  A61K31/519 ,  A61K31/54 ,  A61K31/542 ,  A61P25/00 ,  A61P25/20 ,  A61P25/22 ,  A61P25/24 ,  A61P43/00 ,  C07D20060101 ,  C07D207/00 ,  C07D209/02 ,  C07D209/52 ,  C07D221/00 ,  C07D239/00 ,  C07D401/04 ,  C07D401/06 ,  C07D401/14 ,  C07D403/00 ,  C07D403/04 ,  C07D403/06 ,  C07D403/14 ,  C07D409/04 ,  C07D409/06 ,  C07D409/14 ,  C07D417/14 ,  C07D471/04 ,  C07D487/04 ,  C07D495/04

CPC classification number: C07D403/06 ,  C07D471/04 ,  C07D495/04 ,  C07D513/04

公开(公告)号：AT116972T

公开(公告)日：1995-01-15

申请号：AT90113143

申请日：1990-07-10

Applicant: BASF AG

Inventor： RENDENBACH-MUELLER BEATRICE DR ,  UNGER LILIANE DR ,  TESCHENDORF HANS-JUERGEN DR

IPC: C07D277/20 ,  A61K31/44 ,  A61K31/445 ,  A61K31/495 ,  A61K31/505 ,  A61P25/00 ,  A61P43/00 ,  C07D277/38 ,  C07D277/40 ,  C07D277/42 ,  C07D277/46 ,  C07D417/00 ,  C07D417/06 ,  C07D417/12 ,  C07D417/14

公开(公告)号：DE4243287A1

公开(公告)日：1993-12-23

申请号：DE4243287

申请日：1992-12-21

Applicant: BASF AG

Inventor： STEINER GERD DR ,  UNGER LILIANE DR ,  BEHL BERTHOLD DR ,  TESCHENDORF HANS-JUERGEN DR ,  MUNSCHAUER RAINER DR

IPC: C07D513/04 ,  A61K20060101 ,  A61K31/33 ,  A61K31/395 ,  A61K31/40 ,  A61K31/4045 ,  A61K31/4184 ,  A61K31/505 ,  A61K31/506 ,  A61K31/513 ,  A61K31/517 ,  A61K31/519 ,  A61K31/54 ,  A61K31/542 ,  A61P25/00 ,  A61P25/20 ,  A61P25/22 ,  A61P25/24 ,  A61P43/00 ,  C07D20060101 ,  C07D207/00 ,  C07D209/02 ,  C07D209/52 ,  C07D221/00 ,  C07D239/00 ,  C07D401/04 ,  C07D401/06 ,  C07D401/14 ,  C07D403/00 ,  C07D403/04 ,  C07D403/06 ,  C07D403/14 ,  C07D409/04 ,  C07D409/06 ,  C07D409/14 ,  C07D417/14 ,  C07D471/04 ,  C07D487/04 ,  C07D495/04

Abstract: Compounds having formula (I), in which R , R , n, R , A, X, Y and Z have the meaning given in the description, are disclosed, as well as their preparation. These new compounds are useful for controlling diseases.

公开(公告)号：AT92069T

公开(公告)日：1993-08-15

申请号：AT88107762

申请日：1988-05-13

Applicant: BASF AG

Inventor： STEINER GERD DR ,  PFISTER JUERGEN DR ,  TESCHENDORF HANS-JUERGEN DR ,  UNGER LILIANE DR ,  BINDER RUDOLF DR

IPC: A61K31/55 ,  A61P21/02 ,  A61P25/00 ,  A61P25/02 ,  A61P25/20 ,  C07D487/04

公开(公告)号：AT17945T

公开(公告)日：1986-02-15

申请号：AT83111275

申请日：1983-11-11

Applicant: BASF AG

Inventor： TREIBER HANS JOERG DR ,  HOFMANN HANS PETER DR ,  KREISKOTT HORST PROF DR ,  TESCHENDORF HANS-JUERGEN DR ,  TRAUT MARTIN DR

IPC: A61K31/55 ,  A61P25/24 ,  A61P25/26 ,  C07D267/08 ,  C07D267/10

公开(公告)号：AT16382T

公开(公告)日：1985-11-15

申请号：AT83111501

申请日：1983-11-17

Applicant: BASF AG

Inventor： SEITZ WERNER DR ,  TESCHENDORF HANS-JUERGEN DR ,  MICHEL ALFRED DR ,  TRAUT MARTIN DR ,  HOFMANN HANS PETER DR ,  KREISKOTT HORST PROF DR

IPC: C07C225/18 ,  A61K31/135 ,  A61K31/205 ,  A61K31/395 ,  A61P25/24 ,  A61P25/26 ,  C07D207/08 ,  C07D211/32 ,  C07D295/10 ,  C07D295/116 ,  C07D295/12 ,  C07D295/145 ,  C07C97/10

公开(公告)号：DE3171074D1

公开(公告)日：1985-07-25

申请号：DE3171074

申请日：1981-12-23

Applicant: BASF AG

Inventor： THIEME PETER C DR ,  STEINER GERD DR ,  ROHR WOLFGANG DR ,  LENKE DIETER DR ,  GRIES JOSEF DR ,  WEIFENBACH HARALD DR ,  TESCHENDORF HANS-JUERGEN DR ,  HOFMANN HANS PETER DR ,  KREISKOTT HORST DR

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/415 ,  A61K31/495 ,  A61K31/496 ,  A61P9/02 ,  A61P11/00 ,  A61P25/20 ,  C07D231/12 ,  C07D233/60 ,  C07D233/61 ,  C07D271/10 ,  C07D295/06 ,  C07D295/067 ,  C07D295/096 ,  C07D521/00

Abstract: Novel phenylpiperazinylpropane and -butane derivatives of hetarylphenols and hetarylanilines of the formula where R1 is hydrogen or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, X is oxygen or an NH group, and the heterocyclic structure Het. is 1,3,4-oxadiazolyl, triazolyl, imidazolyl or pyrazolyl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly sedative, neuroleptic and hypotensive properties.

公开(公告)号：DE3064096D1

公开(公告)日：1983-08-18

申请号：DE3064096

申请日：1980-05-05

Applicant: BASF AG

Inventor： STEINER GERD DR ,  FRANKE ALBRECHT DR ,  LENKE DIETER DR ,  TESCHENDORF HANS-JUERGEN DR ,  WORSTMANN WOLFGANG DR ,  KREISKOTT HORST DR

IPC: A61K31/55 ,  A61P25/18 ,  C07D223/20 ,  C07D401/06 ,  C07D403/04

Abstract: 6-Substituted 11-alkylene-morphanthridines, also referred to as 11-alkylene-dibenzo[b,e]-azepines, their pure cis- and trans-isomers, processes for their preparation, and therapeutic agents containing these compounds, which may be used as drugs, in particular neuroleptics, sedatives, hypnotics, analgesics, antidepressants or agents for treating Parkinson's syndrome.