公开(公告)号：CZ284463B6

公开(公告)日：1998-12-16

申请号：CZ278593

申请日：1993-12-16

Applicant: BASF AG

Inventor： STEINER GERD DR ,  UNGER LILIANE DR ,  BEHL BERTHOLD DR ,  TESCHENDORF HANS-JUERGEN DR

IPC: C07D209/02 ,  A61K31/40

Abstract: N-substd. 3-azabicyclo(3.2.0)heptane derivs. of formula (I) and their acid addn. salts are new. In (I), R1 = phenyl, thienyl or pyrrole, all opt. substd. by halo, OMe, OH, amino or NO2; R2 is H or phenyl (opt. substd. by halo); n = 1-4; A = H, CH=CH2, NR6-CO-Ar or C(R3)(R4)Ar; Ar = phenyl substd. by R5; R3 = H, OH or phenyl (opt. substd. by F, Cl or Br); R4 = H; or R3+R4 = O; R5 = H, F, Cl or Br; and R6 = H or Me.

公开(公告)号：CZ31097A3

公开(公告)日：1997-10-15

申请号：CZ31097

申请日：1995-07-21

Applicant: BASF AG

Inventor： STEINER GERD DR ,  MUNSCHAUER RAINER DR ,  HOGER THOMAS DR ,  UNGER LILIANE DR ,  TESCHENDORF HANS JURGEN DR

IPC: C07D401/06 ,  A61K31/40 ,  A61K31/415 ,  A61K31/47 ,  A61K31/505 ,  A61P25/18 ,  A61P43/00 ,  C07D403/06 ,  C07D471/04 ,  C07D513/04

Abstract: PCT No. PCT/EP95/02893 Sec. 371 Date Sep. 18, 1997 Sec. 102(e) Date Sep. 18, 1997 PCT Filed Jul. 21, 1995 PCT Pub. No. WO96/04272 PCT Pub. Date Feb. 15, 1996N-substitued 3-azabicyclo[3.2.0]heptane derivatives of formula (I) in which R1, R2, A, X, Y and Z have the meanings given in the description, their method of preparation and their use as pharmacological agents.

公开(公告)号：DE4427648A1

公开(公告)日：1996-02-08

申请号：DE4427648

申请日：1994-08-04

Applicant: BASF AG

Inventor： STEINER GERD DR ,  MUNSCHAUER RAINER DR ,  HOEGER THOMAS DR ,  UNGER LILIANE DR ,  TESCHENDORF HANS-JUERGEN DR ME

IPC: C07D401/06 ,  A61K31/40 ,  A61K31/415 ,  A61K31/47 ,  A61K31/505 ,  A61P25/18 ,  A61P43/00 ,  C07D403/06 ,  C07D471/04 ,  C07D513/04 ,  C07D513/02

Abstract: Compounds are disclosed having the formula (I), in which R , R , A, X, Y and Z have the meanings given in the description, as well as their preparation. These new compounds are useful for fighting diseases.

公开(公告)号：CZ9302785A3

公开(公告)日：1995-07-12

申请号：CZ278593

申请日：1993-12-16

Applicant: BASF AG

Inventor： STEINER GERD DR ,  UNGER LILIANE DR ,  BEHL BERTHOLD DR ,  TESCHENDORF HANS-JUERGEN DR

IPC: C07D209/02 ,  A61K31/40

公开(公告)号：CZ9403237A3

公开(公告)日：1995-05-17

申请号：CZ323794

申请日：1993-06-08

Applicant: BASF AG

Inventor： STEINER GERD DR ,  UNGER LILIANE DR ,  BEHL BERTHOLD DR ,  TESCHENDORF HANS-JUERGEN DR ,  MUNSCHAUER RAINER DR

IPC: C07D513/04 ,  A61K20060101 ,  A61K31/33 ,  A61K31/395 ,  A61K31/40 ,  A61K31/4045 ,  A61K31/4184 ,  A61K31/505 ,  A61K31/506 ,  A61K31/513 ,  A61K31/517 ,  A61K31/519 ,  A61K31/54 ,  A61K31/542 ,  A61P25/00 ,  A61P25/20 ,  A61P25/22 ,  A61P25/24 ,  A61P43/00 ,  C07D20060101 ,  C07D207/00 ,  C07D209/02 ,  C07D209/52 ,  C07D221/00 ,  C07D239/00 ,  C07D401/04 ,  C07D401/06 ,  C07D401/14 ,  C07D403/00 ,  C07D403/04 ,  C07D403/06 ,  C07D403/14 ,  C07D409/04 ,  C07D409/06 ,  C07D409/14 ,  C07D417/14 ,  C07D471/04 ,  C07D487/04 ,  C07D495/04

CPC classification number: C07D403/06 ,  C07D471/04 ,  C07D495/04 ,  C07D513/04

公开(公告)号：DE4243287A1

公开(公告)日：1993-12-23

申请号：DE4243287

申请日：1992-12-21

Applicant: BASF AG

Inventor： STEINER GERD DR ,  UNGER LILIANE DR ,  BEHL BERTHOLD DR ,  TESCHENDORF HANS-JUERGEN DR ,  MUNSCHAUER RAINER DR

IPC: C07D513/04 ,  A61K20060101 ,  A61K31/33 ,  A61K31/395 ,  A61K31/40 ,  A61K31/4045 ,  A61K31/4184 ,  A61K31/505 ,  A61K31/506 ,  A61K31/513 ,  A61K31/517 ,  A61K31/519 ,  A61K31/54 ,  A61K31/542 ,  A61P25/00 ,  A61P25/20 ,  A61P25/22 ,  A61P25/24 ,  A61P43/00 ,  C07D20060101 ,  C07D207/00 ,  C07D209/02 ,  C07D209/52 ,  C07D221/00 ,  C07D239/00 ,  C07D401/04 ,  C07D401/06 ,  C07D401/14 ,  C07D403/00 ,  C07D403/04 ,  C07D403/06 ,  C07D403/14 ,  C07D409/04 ,  C07D409/06 ,  C07D409/14 ,  C07D417/14 ,  C07D471/04 ,  C07D487/04 ,  C07D495/04

Abstract: Compounds having formula (I), in which R , R , n, R , A, X, Y and Z have the meaning given in the description, are disclosed, as well as their preparation. These new compounds are useful for controlling diseases.

公开(公告)号：AT92069T

公开(公告)日：1993-08-15

申请号：AT88107762

申请日：1988-05-13

Applicant: BASF AG

Inventor： STEINER GERD DR ,  PFISTER JUERGEN DR ,  TESCHENDORF HANS-JUERGEN DR ,  UNGER LILIANE DR ,  BINDER RUDOLF DR

IPC: A61K31/55 ,  A61P21/02 ,  A61P25/00 ,  A61P25/02 ,  A61P25/20 ,  C07D487/04

公开(公告)号：DE3717069A1

公开(公告)日：1988-12-08

申请号：DE3717069

申请日：1987-05-21

Applicant: BASF AG

Inventor： STEINER GERD DR ,  TESCHENDORF HANS-JUERGEN DR ME ,  UNGER LILIANE DR ,  BINDER RUDOLF DR

IPC: A61K31/55 ,  A61P21/02 ,  A61P25/00 ,  A61P25/20 ,  C07D495/04

Abstract: Compounds of the formula I where R1, R2, R3 and A have the meanings stated in the specification, as well as the use thereof for controlling diseases, are described.

公开(公告)号：AT20345T

公开(公告)日：1986-06-15

申请号：AT83103054

申请日：1983-03-28

Applicant: BASF AG

Inventor： STEINER GERD DR ,  FRIEDRICH LUDWIG DR ,  LENKE DIETER DR

IPC: A61K31/55 ,  A61P1/04 ,  C07D223/20

公开(公告)号：AT18039T

公开(公告)日：1986-03-15

申请号：AT84102632

申请日：1984-03-10

Applicant: BASF AG

Inventor： STEINER GERD DR

IPC: C07C45/00 ,  C07C46/06 ,  C07C50/24 ,  C07C67/00 ,  C07C325/00 ,  C07C327/20 ,  C07C327/26 ,  C07D333/72 ,  C07D495/04 ,  C07C153/07