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公开(公告)号:CA2375262C
公开(公告)日:2009-04-07
申请号:CA2375262
申请日:2000-06-21
Applicant: BASF AG
Inventor: KASEL WOLFGANG , MUNDINGER KLAUS , KINGMA AREND JOUKE , KOSER STEFAN , DOCKNER TONI
Abstract: A process for preparing bisphenol alkoxylates comprises reacting at least one bisphenol with alkylene oxide in the presence of a phosphine catalyst which is essentially free of alkali metal hydroxide.
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公开(公告)号:NZ516807A
公开(公告)日:2004-12-24
申请号:NZ51680700
申请日:2000-07-11
Applicant: BASF AG
Inventor: KNOPP MONIKA , KOSER STEFAN , SCHAFER BERND
IPC: C07D277/20 , C07D277/56
Abstract: The invention relates to processes for preparing 2-aminomethyl-4-cyanothiazole and its salts of the formulae Ia and Ibin whichn=1 or 2 andfor n=1, X is chloride, bromide, triflate and hydrogen sulfate andfor n=2, X is sulfate, which comprises the process step where the aminonitrile of the formula IIis stirred with a cysteine ester of the formula III,in which R is branched or linear C1-10-alkyl orwhere n=0, 1 or 2 and R is branched or linear C1-C10C10-alkyl or C1-C4-alkoxy or C1-C4-dialkylamino in an inert solvent in the presence of a base at from 0° C. to 80° C. until the reaction has essentially proceeded to completion, and to the compounds of the formulae Ia and Ib.
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公开(公告)号:AU773056B2
公开(公告)日:2004-05-13
申请号:AU6264900
申请日:2000-06-21
Applicant: BASF AG
Inventor: KOSER STEFAN , MUNDINGER KLAUS , KASEL WOLFGANG , KINGMA AREND JOUKE , DOCKNER TONI
Abstract: Preparation of bisphenol alkoxylates comprises reacting bisphenol(s) with an alkylene oxide in the presence of a phosphine catalyst free from alkali metal hydroxide. An independent claim is also included for the use of specified triaryl-phosphine catalysts in the preparation of bisphenol alkoxylates.
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公开(公告)号:ES2204660T3
公开(公告)日:2004-05-01
申请号:ES00949207
申请日:2000-06-21
Applicant: BASF AG
Inventor: KOSER STEFAN , MUNDINGER KLAUS , KASEL WOLFGANG , KINGMA AREND JOUKE , DOCKNER TONI
Abstract: Preparation of bisphenol alkoxylates comprises reacting bisphenol(s) with an alkylene oxide in the presence of a phosphine catalyst free from alkali metal hydroxide. An independent claim is also included for the use of specified triaryl-phosphine catalysts in the preparation of bisphenol alkoxylates.
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公开(公告)号:DE50003013D1
公开(公告)日:2003-08-28
申请号:DE50003013
申请日:2000-06-21
Applicant: BASF AG
Inventor: KOSER STEFAN , MUNDINGER KLAUS , KASEL WOLFGANG , KINGMA JOUKE , DOCKNER TONI
Abstract: Preparation of bisphenol alkoxylates comprises reacting bisphenol(s) with an alkylene oxide in the presence of a phosphine catalyst free from alkali metal hydroxide. An independent claim is also included for the use of specified triaryl-phosphine catalysts in the preparation of bisphenol alkoxylates.
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公开(公告)号:AT245617T
公开(公告)日:2003-08-15
申请号:AT00949207
申请日:2000-06-21
Applicant: BASF AG
Inventor: KOSER STEFAN , MUNDINGER KLAUS , KASEL WOLFGANG , KINGMA AREND JOUKE , DOCKNER TONI
Abstract: Preparation of bisphenol alkoxylates comprises reacting bisphenol(s) with an alkylene oxide in the presence of a phosphine catalyst free from alkali metal hydroxide. An independent claim is also included for the use of specified triaryl-phosphine catalysts in the preparation of bisphenol alkoxylates.
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公开(公告)号:BG63697B1
公开(公告)日:2002-09-30
申请号:BG10183597
申请日:1997-08-15
Applicant: BASF AG
Inventor: BOEHM HANS-JOACHIM , HOEFFKEN HANS W , HORNBERGER WILFRIED , KOSER STEFAN , MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , ZIERKE THOMAS
IPC: A61K31/00 , A61K38/55 , A61P7/02 , C07D205/04 , C07D207/16 , C07D213/53 , C07D213/63 , C07D213/72 , C07D213/78 , C07D213/79 , C07D239/28 , C07D241/14 , C07D241/24 , C07D401/12 , C07K5/06 , C07K5/062 , C07K5/078 , A61K31/40 , A61K31/445 , A61K31/495
Abstract: The description relates to compounds of formula in which A, B, D, R' and R have the meanings given in the specification. the compounds am suitable for the treatment of diseases The novel compounds are produced via compounds of the formula H2N-CH2.G-M in which G and M have the meanings given in the specification. 3 claims
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公开(公告)号:CZ20014470A3
公开(公告)日:2002-05-15
申请号:CZ20014470
申请日:2000-06-21
Applicant: BASF AG
Inventor: KOSER STEFAN , MUNDINGER KLAUS , KASEL WOLFGANG , KINGMA AREND JOUKE , DOCKNER TONI
Abstract: Preparation of bisphenol alkoxylates comprises reacting bisphenol(s) with an alkylene oxide in the presence of a phosphine catalyst free from alkali metal hydroxide. An independent claim is also included for the use of specified triaryl-phosphine catalysts in the preparation of bisphenol alkoxylates.
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公开(公告)号:NO20020328L
公开(公告)日:2002-01-31
申请号:NO20020328
申请日:2002-01-22
Applicant: BASF AG
Inventor: KNOPP MONIKA , KOSER STEFAN , SCHAEFER BERND
IPC: C07D277/20 , C07D277/56
Abstract: The invention relates to processes for preparing 2-aminomethyl-4-cyanothiazole and its salts of the formulae Ia and Ibin whichn=1 or 2 andfor n=1, X is chloride, bromide, triflate and hydrogen sulfate andfor n=2, X is sulfate, which comprises the process step where the aminonitrile of the formula IIis stirred with a cysteine ester of the formula III,in which R is branched or linear C1-10-alkyl orwhere n=0, 1 or 2 and R is branched or linear C1-C10C10-alkyl or C1-C4-alkoxy or C1-C4-dialkylamino in an inert solvent in the presence of a base at from 0° C. to 80° C. until the reaction has essentially proceeded to completion, and to the compounds of the formulae Ia and Ib.
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公开(公告)号:DE19934066A1
公开(公告)日:2001-01-25
申请号:DE19934066
申请日:1999-07-23
Applicant: BASF AG
Inventor: KNOPP MONIKA , KOSER STEFAN , SCHAEFER BERND
IPC: C07D277/20 , C07D277/56 , C07D277/12
Abstract: 2-Aminomethyl-4-cyanothiazole (I) and its salts are new. 2-Aminomethyl-4-cyanothiazole (I) and its salts of formula are new. n = 1 or 2; and X = Cl, Br, SO3CF3, HSO4 or 1/2 SO4. Independent claims are included for: (1) the preparation of (I); (2) the preparation of thiazolecarboxylic acid ester intermediates of formula (V); and (3) the new intermediate N-(tert. butoxycarbonyl)-2-aminomethyl-4-cyanothiazole of formula (VII). R1 = 1-10C alkyl or -(CH2)m-Ar; Ar = phenyl (optionally monosubstituted by 1-10C alkyl, 1-4C alkoxy or di-(1-4C alkyl)-amino); and m = 0-2.
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