公开(公告)号：AU2015314165B2

公开(公告)日：2019-06-06

申请号：AU2015314165

申请日：2015-09-11

Applicant: BASF SE

Inventor： PUHL MICHAEL ,  DITRICH KLAUS ,  KELLER ANDREAS ,  DIMITROVA PEPA ,  WEINGARTEN MELANIE ,  SIEGEL WOLFGANG

IPC: C07H3/06 ,  A23L33/10 ,  C07H15/26

Abstract: The present invention relates to a method for preparing 2'-O-fucosyllactose, the 2'-O-fucosyllactose obtainable by this method and the use thereof. The method comprises reacting the persilylated, protected fucose derivatives of the formula (I) below, with at least one tri(C

公开(公告)号：CA2960056A1

公开(公告)日：2016-03-17

申请号：CA2960056

申请日：2015-09-11

Applicant: BASF SE

Inventor： PUHL MICHAEL ,  DITRICH KLAUS ,  KELLER ANDREAS ,  DIMITROVA PEPA ,  WEINGARTEN MELANIE ,  SIEGEL WOLFGANG

IPC: C07H15/26 ,  A23L29/30 ,  A23L33/125 ,  C07H3/06 ,  C07H13/04 ,  C07H13/08

Abstract: The present invention relates to a method for preparing 2'-O-fucosyllactose, the 2'-O-fucosyllactose obtainable by this method and the use thereof. The method comprises reacting the persilylated, protected fucose derivatives of the formula (I) below, with at least one tri(C1-C6-alkyl)silyl iodide and subsequently reacting the product thus obtained with the compound of the general formula (II), in the presence of a base. In the formulae (I) and (II), the variables are each defined as follows: RSi are the same or different and are a residue of the formula SiRaRbRc; R1 is a C(=O)-R11 residue or an SiR12R13R14 residue, R2 are the same or different and are C1-C8-alkyl or together form a linear C3-C6- alkanediyl, which is unsubstituted or has 1 to 6 methyl groups as substituents; R3 are the same or different and are C1-C8-alkyl or together form a linear C1-C4- alkanediyl, which is unsubstituted or has 1 to 6 methyl groups as substituents.