Method for preparing 2'-O-fucosyllactose

    公开(公告)号:AU2015314165A1

    公开(公告)日:2017-03-16

    申请号:AU2015314165

    申请日:2015-09-11

    Applicant: BASF SE

    Abstract: The present invention relates to a method for preparing 2′-O-fucosyllactose, the 2′-O-fucosyllactose obtainable by this method and the use thereof. The method comprises reacting the persilylated, protected fucose derivatives of the formula (I) below, with at least one tri(C1-C6-alkyl)silyl iodide and subsequently reacting the product thus obtained with the compound of the general formula (II), in the presence of a base.In the formulae (I) and (II), the variables are each defined as follows:RSi are the same or different and are a residue of the formula SiRaRbRc;R1 is a C(═O)—R11 residue or an SiR12R13R14 residue,R2 are the same or different and are C1-C8-alkyl or together form a linear C3-C6-alkanediyl, which is unsubstituted or has 1 to 6 methyl groups as substituents;R3 are the same or different and are C1-C8-alkyl or together form a linear C1-C4-alkanediyl, which is unsubstituted or has 1 to 6 methyl groups as substituents.

    Método de preparación de éteres de dioles cicloalifáticos o aralifáticos

    公开(公告)号:ES2923914T3

    公开(公告)日:2022-10-03

    申请号:ES18811030

    申请日:2018-12-03

    Applicant: BASF SE

    Abstract: La presente invención se refiere a un método para preparar un dialquilo o dialquenil éter de un diol cicloalifático o aralifático, que comprende (i) hacer reaccionar el diol cicloalifático o aralifático con sodio metálico en un disolvente orgánico aprótico en presencia de una cantidad catalítica de al menos un monoéter-monoalcohol de fórmula (I) en la que Y es idéntico o diferente y se selecciona de alquileno C2-C4, n es un número entero en el rango de 1 a 10, y R1 es alquilo C1-C4, por lo que el dialcoholato disódico correspondiente se obtiene haciendo reaccionar el dialcoholato disódico obtenido en la etapa (i) con un reactivo de alquenilación de alquilación. (Traducción automática con Google Translate, sin valor legal)

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