公开(公告)号：BR0107772A

公开(公告)日：2002-11-05

申请号：BR0107772

申请日：2001-11-13

Applicant: BAXTER INT

Inventor： ODAK SANJAY V ,  VANDLIK MARK R ,  WESTBERG TOM

IPC: A61M1/02 ,  A61M1/26 ,  A61M1/38 ,  B01D17/02 ,  B01D17/12

Abstract: A pneumatic pump manifold disposable system, configured as a cassette, is used for the purpose of red cell and plasma apheresis. The cassette integrates a separation device, manifold system, macro-aggregate filter, and five pumping chambers for the purpose of separating plasma and red cells from the whole blood. The cassette system, with the separation device directly attached without tubing, simplifies the loading of the disposable set into the hardware, and reduces the manufacturing complexity of the set. The system allows for plasma, plasma and red cells, or just red cells to be stored in long term storage containers after a procedure.

公开(公告)号：BR0007066A

公开(公告)日：2001-07-31

申请号：BR0007066

申请日：2000-08-29

Applicant: BAXTER INT

Inventor： WESTBERG TOM ,  VISHNOI ROHIT ,  VANDLIK MARK R

IPC: A61M1/02 ,  A61M1/10 ,  A61M1/30 ,  A61M1/36 ,  A61M37/00 ,  F04B13/02 ,  F04B43/02 ,  F04B49/06 ,  C02F1/00 ,  C02F1/44 ,  B01D37/00 ,  B01D61/00 ,  B01D63/00 ,  F04B49/00 ,  F04B9/08 ,  F04B17/00 ,  F04B35/00

Abstract: Blood processing systems and related methods place first and second fluid pressure actuated pump stations in in-line communication between a source and a destination. The systems and methods apply fluid pressure pump strokes to the first and second pump stations to convey fluid from the source to the destination. The systems and methods switch between a first flow mode and a second flow mode. In the first flow mode, the pump strokes draw a fluid volume into the first pump station from the source and expel a fluid volume from the second pump station to the destination. In the second flow mode, the pump strokes draw a fluid volume into the second pump station from the source and expel a fluid volume from the first pump station to the destination. The systems and methods synchronize the pump strokes so that fluid flow from the source is essentially continuous while fluid flow to the destination is pulsatile.

公开(公告)号：BR0007065A

公开(公告)日：2001-07-31

申请号：BR0007065

申请日：2000-08-29

Applicant: BAXTER INT

Inventor： WESTBERG TOM ,  VISHNOI ROHIT ,  VANDLIK MARK R

IPC: A61M1/02 ,  A61M1/10 ,  A61M1/30 ,  A61M1/36 ,  A61M37/00 ,  C02F1/00 ,  C02F1/44 ,  B01D37/00 ,  B01D61/00 ,  B01D63/00 ,  F04B49/00 ,  F04B9/08 ,  F04B17/00 ,  F04B35/00

Abstract: A multiple function pump station performs different on-line processing tasks. The pump station can be operated in one mode to draw blood from a donor and, in another mode, be operated to return blood to the donor. The pump station used to draw blood from a donor can also be used to perform subsequent blood processing tasks, such as mixing or processing additive fluids with the blood, or transfering a harvested blood component to a storage container, or finishing the processing of a harvested blood component.

公开(公告)号：BR0007058A

公开(公告)日：2001-07-24

申请号：BR0007058

申请日：2000-08-29

Applicant: BAXTER INT

Inventor： WESTBERG TOM ,  VISHNOI ROHIT ,  VANDLIK MARK R

IPC: F04B9/123 ,  A61B5/15 ,  A61M1/02 ,  A61M1/10 ,  A61M1/30 ,  A61M1/36 ,  F04B13/02 ,  F04B43/02 ,  F04B43/06 ,  F04B49/06 ,  F04B49/00

Abstract: Programmable, fluid pressure actuated blood processing systems (10) and methods are used in association with a blood separation device (18). The systems and methods employ a cassette (28), which contains several preformed, pneumatically actuated pump stations (PP1-PP4), several preformed fluid flow paths (F1-F38), and several preformed, pneumatically actuated (VA1-VA23) valves (1-23) in the fluid flow paths. The systems and methods also employ progr ammable pneumatic actuators (PA1-PA4) to hold the cassette and selectively apply pneumatic force to the valves and the pump stations.

公开(公告)号：CA2347626A1

公开(公告)日：2001-03-15

申请号：CA2347626

申请日：2000-08-29

Applicant: BAXTER INT

Inventor： VISHNOI ROHIT ,  VANDLIK MARK R ,  WESTBERG TOM

IPC: A61M1/02 ,  A61M1/10 ,  A61M1/30 ,  A61M1/36 ,  A61M37/00 ,  F04B13/02 ,  F04B43/02 ,  F04B49/06 ,  F04B17/00 ,  F04B35/00 ,  F04B49/00 ,  B01D37/00 ,  B01D61/00 ,  B01D63/00 ,  C02F1/00 ,  F04B9/08 ,  C02F1/44

Abstract: Blood processing systems (10) and related methods place first (PP1) and seco nd (PP2) fluid actuated pump stations in in-line communication between a source and a destination. The systems and methods apply fluid pressure pump strokes to the first and second pump stations to convey fluid from the source to the destination. The systems and methods switch between a first flow mode and a second flow mode. The first flow draws a fluid volume into the first pump station from the source and expel a fluid volume from the second pump statio n to the destination. In the second flow mode, the pump strokes draw a fluid volume into the second pump station from the source and expel a fluid volume from the first pump station to the destination. The pump strokes are synchronized so that flow from the source is essentially continuous while fluid flow to the destination is pulsatile.

公开(公告)号：CA2155735A1

公开(公告)日：1995-06-29

申请号：CA2155735

申请日：1994-03-17

Applicant: BAXTER INT

Inventor： GIESLER RICHARD C ,  ELLIS DALE R ,  VANDLIK MARK R

IPC: A61M5/168 ,  A61M1/36 ,  A61M5/14 ,  F04B43/08

Abstract: A drip chamber (506) includes a cap (510) that extends the field of view of a droplet in a vertical direction above the plane of the droplet, as well as horizontally in the plane of the droplet. The drip chamber has a deformable body and an interior volume to accommodate manual air purging and priming by squeezing the body.

公开(公告)号：ES2269177T3

公开(公告)日：2007-04-01

申请号：ES00961406

申请日：2000-08-29

Applicant: BAXTER INT

Inventor： VISHNOI ROHIT ,  WESTBERG TOM ,  MULLER MATTHEW R ,  SMITH KELLY B ,  JOIE MICHEL L F ,  VANDLIK MARK R

IPC: A61M1/36 ,  G01N33/48 ,  A61M1/02 ,  A61M1/34 ,  B01D17/02 ,  B01D21/24 ,  B04B5/00 ,  B04B5/04 ,  G01N21/27 ,  G01N21/35 ,  G01N33/483 ,  G01N33/49

Abstract: REIVINDICACIONES 1. Sistema de separación de sangre (10) que comprende: un dispositivo (14, 18) que, en uso, funciona para separar la sangre total en glóbulos rojos y plasma, una línea de entrada de sangre total (290) para transportar un flujo de sangre total dentro del dispositivo, una línea de recogida de plasma (292) fuera del dispositivo para transportar un flujo de plasma desde el dispositivo, y una línea de recogida de glóbulos rojos (294) fuera del dispositivo para transportar un flujo de glóbulos rojos desde el dispositivo, caracterizado porque el dispositivo comprende una primera unidad de detección (334) que incluye un primer sensor en la línea de recogida de plasma que funciona detectando la presencia de al menos una especie de un componente celular sanguíneo en el flujo de plasma y que genera una primera salida, una segunda unidad de detección (336) que incluye un segundo sensor en la línea de recogida de glóbulos rojos que funciona detectando el hematocrito de glóbulos rojos enel flujo de glóbulos rojos y que genera una segunda salida, y un controlador (16) que funciona controlando los flujos en la línea de recogida de plasma y la línea de recogida de glóbulos rojos en base a la primera y segunda salidas.

公开(公告)号：AT334708T

公开(公告)日：2006-08-15

申请号：AT00961406

申请日：2000-08-29

Applicant: BAXTER INT

Inventor： VISHNOI ROHIT ,  WESTBERG TOM ,  MULLER MATTHEW R ,  SMITH KELLY B ,  JOIE MICHEL L F ,  VANDLIK MARK R

IPC: G01N33/48 ,  A61M1/02 ,  A61M1/34 ,  A61M1/36 ,  B01D17/02 ,  B01D21/24 ,  B04B5/00 ,  G01N21/27 ,  G01N21/35 ,  G01N33/483 ,  G01N33/49 ,  B04B5/04

Abstract: A blood separation system (10) is described. The system comprises a device (14, 18) which, in use, operates to separate whole blood into red blood cells and plasma, a whole blood inlet line (290) for conveying a flow of whole blood into the device, a plasma collection line (292) for conveying a flow of plasma from the device, and a red blood cell collection line (294) for conveying a flow of red blood cells from the device. A first sensing assembly (334) including a first sensor in the plasma collection line is provided which in use operates to detect a characteristic of plasma in the flow of plasma and to generate a first output. A second sensing assembly (336) including a second sensor in the red blood cell collection line is provided which in use operates to detect a characteristic of red blood cells in the flow of red blood cells and to generate a second output. A controller (16) operates to control flows in the plasma collection line and the red blood cell collection line based upon the first and second outputs.

公开(公告)号：AU780420B2

公开(公告)日：2005-03-17

申请号：AU7335900

申请日：2000-08-29

Applicant: BAXTER INT

Inventor： WESTBERG TOM ,  VISHNOI ROHIT ,  VANDLIK MARK R

IPC: A61M1/02 ,  A61M1/10 ,  A61M1/30 ,  A61M1/36 ,  A61M37/00 ,  B01D37/00 ,  B01D61/00 ,  B01D63/00 ,  C02F1/00 ,  C02F1/44 ,  F04B9/08 ,  F04B17/00 ,  F04B35/00 ,  F04B49/00

Abstract: A multiple function pump station performs different on-line processing tasks. The pump station can be operated in one mode to draw blood from a donor and, in another mode, be operated to return blood to the donor. The pump station used to draw blood from a donor can also be used to perform subsequent blood processing tasks, such as mixing or processing additive fluids with the blood, or transfering a harvested blood component to a storage container, or finishing the processing of a harvested blood component.

公开(公告)号：CA2462718A1

公开(公告)日：2003-04-24

申请号：CA2462718

申请日：2002-10-02

Applicant: BAXTER INT

Inventor： KAST MICHAEL J ,  VANDLIK MARK R ,  SMITH KELLY B

IPC: A61M1/02 ,  A61K35/14 ,  A61K35/18 ,  A61M1/10 ,  A61M1/30 ,  A61M1/34 ,  A61M1/36 ,  A61P7/00 ,  A61M37/00 ,  C02F1/00 ,  B01D33/15

Abstract: Blood processing systems and methods (10) convey blood cells from a blood ce ll source into a blood component collection flow channel that includes a blood cell storage container and an in-line filter to remove leukocytes from blood cells before entering the blood cell storage container. The systems and methods also convey additive solution from an additive solution source into the blood component collection flow channel. The systems and methods alterna te the conveyance of blood cells through the filter with the conveyance of additive solution through the filter.