-
1.发明申请CONTINUOUS CENTRIFUGATION PROCESS FOR THE SEPARATION OF BIOLOGIC COMPONENTS FROM HETEROGENEOUS CELL POPULATIONS 审中-公开用于分离异源细胞群体生物成分的连续离心方法
公开(公告)号：WO9427698A3
公开(公告)日：1996-10-10
申请号：PCT/US9305735
申请日：1993-06-15
Applicant: BAXTER INT
Inventor： LAKE WILLIAM C , GIESLER RICHARD , VAN EPPS DENNIS , CHAPMAN JOHN R , MARTINSON JEFFREY A , ELLIS DALE R , AONO FREDERICK , BISCHOF DANIEL F
IPC: G01N33/48 , A61K35/14 , A61K35/24 , A61M1/36 , B03B5/28 , C12M1/00 , C12N5/00 , C12N5/06 , C12Q1/02 , C12Q1/24 , G01N33/49 , G01N33/50 , G01N33/53 , G01N33/569 , B01D
CPC classification number: G01N33/56972 , A61M1/3618 , A61M1/362 , A61M1/3696 , C12Q1/24 , G01N33/5005 , G01N33/569
Abstract: A method combining the techniques of immunoaffinity separation and continuous flow centrifugal separation is provided for selective separation of a nucleated heterogeneous cell population from a heterogeneous cell mixture. The heterogeneous cell mixture is intimately contacted to promote binding thereto by particles having attached a substance that actively binds to a specific desired type of cell out of the cell mixture. The particles are selected so that the sedimentation velocity of the particle/cell conjugate differs sufficiently from those of other cells in the cell mixture to allow its separation by means of a continuous flow cell separator. The method rapidly processes large volumes of cell mixture with the high accuracy expected of immunoaffinity separation and can be used to separate, for example, various types of leukocytes from whole blood, bone marrow concentrate, or a peripheral blood stem cell concentrate; or precursors of lymphokine activated killer cells, tumor infiltrating lymphocyte cells, or activated killer monocytes from lymphocyte or monocyte cell concentrates or from a tissue cell preparation.
-
公开(公告)号：EP0695200A4
公开(公告)日：1997-06-18
申请号：EP94920648
申请日：1994-03-17
Applicant: BAXTER INT
Inventor： GIESLER RICHARD C , ELLIS DALE R , VANDLIK MARK R
CPC classification number: A61M5/1411 , A61M1/30 , A61M1/303 , A61M1/3627 , A61M1/3693 , A61M1/3696 , A61M2005/1403 , A61M2205/12
Abstract: A drip chamber (506) includes a cap (510) that extends the field of view of a droplet in a vertical direction above the plane of the droplet, as well as horizontally in the plane of the droplet. The drip chamber has a deformable body and an interior volume to accommodate manual air purging and priming by squeezing the body.
-
3.发明公开
公开(公告)号：EP0653062A4
公开(公告)日：1997-12-03
申请号：EP93915369
申请日：1993-06-15
Applicant: BAXTER INT
Inventor： LAKE WILLIAM C , GIESLER RICHARD , VAN EPPS DENNIS , CHAPMAN JOHN R , MARTINSON JEFFREY A , ELLIS DALE R , AONO FREDERICK , BISCHOF DANIEL F
IPC: G01N33/48 , A61K35/14 , A61K35/24 , A61M1/36 , B03B5/28 , C12M1/00 , C12N5/00 , C12N5/06 , C12Q1/02 , C12Q1/24 , G01N33/49 , G01N33/50 , G01N33/53 , G01N33/569
CPC classification number: G01N33/56972 , A61M1/3618 , A61M1/362 , A61M1/3696 , C12Q1/24 , G01N33/5005 , G01N33/569
-
4.发明公开ENHANCED YIELD BLOOD PROCESSING SYSTEMS WITH ANGLED INTERFACE CONTROL SURFACE 失效效率提高血液处理系统中，WINKLICHE接口控制面HAVE
公开(公告)号：EP0775007A4
公开(公告)日：1998-03-25
申请号：EP96916681
申请日：1996-05-22
Applicant: BAXTER INT
Inventor： BROWN RICHARD I , FOLEY JOHN T , ELLIS DALE R
IPC: G01N33/48 , A61K35/14 , A61M1/02 , A61M1/30 , A61M1/36 , B01D17/02 , B01D21/24 , B01D21/26 , B04B1/06 , B04B5/04 , B04B7/08 , B04B13/00
CPC classification number: A61M1/0209 , A61M1/025 , A61M1/30 , A61M1/302 , A61M1/303 , A61M1/308 , A61M1/3603 , A61M1/3624 , A61M1/3693 , A61M1/3696 , A61M2202/0427 , A61M2205/331 , A61M2205/3344 , A61M2205/3351 , A61M2205/3355 , A61M2205/3393 , B01D17/0217 , B01D21/003 , B01D21/0087 , B01D21/2405 , B01D21/245 , B01D21/26 , B01D21/262 , B01D21/32 , B01D21/34 , B01D2221/10 , B04B5/0442 , B04B7/08 , B04B13/00 , B04B2005/045 , A61M2202/0071
Abstract: A chamber for rotation about a rotational axis to separate blood components includes first and second spaced apart side walls forming a separation zone. Blood conveyed into the separation zone separates into a first region of cellular components, a second region of plasma, and an interface region between the first and second regions. An outlet conveys the second region of plasma from the separation zone. An interior wall extends into the separation zone to permit passage of the second region of plasma to the outlet while retarding passage of the interface region and the first region of cellular components to the outlet. The tapered second surface has a major axis that is oriented at a non-parallel angle with respect to the axis of the outlet. Due to this orientation, the boundary between the interface region and the other two regions is held uniform along the tapered surface. The boundary does not bulge to spill materials in the first interface region or interface region over the first surface and into the constricted passage. As a result, the second region of plasma is kept essentially free of other materials.
-
5.发明公开ENHANCED YIELD COLLECTION SYSTEMS AND METHODS FOR OBTAINING CONCENTRATED PLATELETS FROM PLATELET-RICH PLASMA. 失效收集与提高效率和系统的方法对保护集约滑落富血小板血浆。
公开(公告)号：EP0618830A4
公开(公告)日：1995-03-29
申请号：EP93909184
申请日：1993-03-23
Applicant: BAXTER INT
Inventor： BROWN RICHARD I , ELLIS DALE R
CPC classification number: A61M1/3693 , A61M1/30 , A61M1/303 , A61M1/308 , A61M1/3696 , B04B5/0442
Abstract: A method for separating platelets from a platelet-rich suspension comprising rotating a separation zone about an axis (14) at a given angular velocity ( OMEGA ), the separation zone including a low-G side (16) located closer to the rotational axis (14) than the other, high-G (18) to create between them a chamber (10) having a radial thickness (h) and an axial height (Z) measured with respect to the axis (14) of rotation, and an inlet (20) for introducing a platelet-rich suspension and the separation zone establishing a relationship between the radial thickness (h) and the axial height (Z) of the chamber (10) that taking into account the given angular velocity of rotation ( OMEGA ) and the given kinematic viscosity (v) of the platelet-rich suspension introduced through the inlet (20), represents a value ( lambda ) that is less than 700, where lambda = (2h )/(Z).
-
Patent Agency Ranking
公开(公告)号：ES2140097T3
公开(公告)日：2000-02-16
申请号：ES96916681
申请日：1996-05-22
Applicant: BAXTER INT
Inventor： BROWN RICHARD I , FOLEY JOHN T , ELLIS DALE R
-
公开(公告)号：CA2155735A1
公开(公告)日：1995-06-29
申请号：CA2155735
申请日：1994-03-17
Applicant: BAXTER INT
Inventor： GIESLER RICHARD C , ELLIS DALE R , VANDLIK MARK R
Abstract: A drip chamber (506) includes a cap (510) that extends the field of view of a droplet in a vertical direction above the plane of the droplet, as well as horizontally in the plane of the droplet. The drip chamber has a deformable body and an interior volume to accommodate manual air purging and priming by squeezing the body.
-
公开(公告)号：CA2140455A1
公开(公告)日：1994-12-08
申请号：CA2140455
申请日：1993-06-15
Applicant: BAXTER INT
Inventor： LAKE WILLIAM C , GIESLER RICHARD , VAN EPPS DENNIS , CHAPMAN JOHN R , MARTINSON JEFFREY A , ELLIS DALE R , AONO FREDERICK , BISCHOF DANIEL F
IPC: G01N33/48 , A61K35/14 , A61K35/24 , A61M1/36 , B03B5/28 , C12M1/00 , C12N5/00 , C12N5/06 , C12Q1/02 , C12Q1/24 , G01N33/49 , G01N33/50 , G01N33/53 , G01N33/569 , A61K35/18 , A61K35/28 , B01D21/26 , C12N1/00
Abstract: A method combining the techniques of immunoaffinity separation and continuous flow centrifugal is provided for selective separation of a nucleated heterogeneous cell population from a heterogeneous cell mixture. The heterogeneous cell mixture is intimately contacted to promote binding thereto by particles having attached a substance that actively binds to a specific desired type of cell out of the cell mixture. The particles are selected so that the sedimentation velocity of the particle/cell conjugate differs sufficiently from those of other cells in the cell mixture to allow its separation by means of a continuous flow cell separator. The method rapidly processes large volumes of cell mixture with the high accuracy expected of immunoaffinity separation and can be used to separate, for example, various types of leukocytes from whole blood, bone marrow concentrate, or a peripheral blood stem cell concentrate; or precursors of lymphokine activated killer cells, tumor infiltrating cells, or activated killer monocytes from lymphocyte or monocyte cell concentrates or from a tissue cell preparation.
-
公开(公告)号：DK0775007T3
公开(公告)日：2000-01-03
申请号：DK96916681
申请日：1996-05-22
Applicant: BAXTER INT
Inventor： FOLEY JOHN T , BROWN RICHARD I , ELLIS DALE R
-
公开(公告)号：NO970536L
公开(公告)日：1997-04-02
申请号：NO970536
申请日：1997-02-06
Applicant: BAXTER INT
Inventor： BROWN RICHARD I , FOLEY JOHN T , ELLIS DALE R
-
-
-
-
-
-
-
-
-
Search Results
15
records
(took 0.021 seconds)
