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公开(公告)号：WO2009099455A1
公开(公告)日：2009-08-13
申请号：PCT/US2008/058715
申请日：2008-03-28
Applicant: COLGATE-PALMOLIVE COMPANY , PRENCIPE, Michael , CUMMINS, Diane , SUBRAMANYAM, Ravi , SULLIVAN, Richard, J. , SANTARPIA, Ralph, Peter , MELLO, Sarita, V. , ZAIDEL, Lynette , CHOPRA, Suman, K. , WANG, Qin , TAMBS, Gary, Edward , BARNES, Virginia, Monsul , WU, Donghui , MORGAN, Andre, M. , KOHLI, Rajnish , ROBINSON, Richard, Scott , LEITE, Sergio , SIMON, Eric, A.
Inventor： PRENCIPE, Michael , CUMMINS, Diane , SUBRAMANYAM, Ravi , SULLIVAN, Richard, J. , SANTARPIA, Ralph, Peter , MELLO, Sarita, V. , ZAIDEL, Lynette , CHOPRA, Suman, K. , WANG, Qin , TAMBS, Gary, Edward , BARNES, Virginia, Monsul , WU, Donghui , MORGAN, Andre, M. , KOHLI, Rajnish , ROBINSON, Richard, Scott , LEITE, Sergio , SIMON, Eric, A.
IPC: A61K8/44 , A61K8/46 , A61Q11/00 , A61K31/198 , A61P1/02
Abstract: This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an anionic surfactant, and to methods of using and of making such compositions.
Abstract translation: 本发明涉及包含游离或盐形式的有效量的碱性氨基酸以及阴离子表面活性剂的口腔护理组合物，以及使用和制备这些组合物的方法。
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公开(公告)号：WO2009099452A1
公开(公告)日：2009-08-13
申请号：PCT/US2008/058679
申请日：2008-03-28
Applicant: COLGATE-PALMOLIVE COMPANY , PRENCIPE, Michael , CUMMINS, Diane , ROBINSON, Richard, Scott , MELLO, Sarita, V. , SULLIVAN, Richard, J. , CHOPRA, Suman, K. , DEPIERRO, Karen , ZAIDEL, Lynette , CHRISTOPOULOU, Constantina , SUBRAMANYAM, Ravi , WU, Donghui , MORGAN, Andre, M. , SANTARPIA III, Ralph, Peter , WANG, Qin , TAMBS, Gary, Edward , KOHLI, Rajnish , BARNES, Virginia, Monsul , LEITE, Sergio , SIMON, Eric, A.
Inventor： PRENCIPE, Michael , CUMMINS, Diane , ROBINSON, Richard, Scott , MELLO, Sarita, V. , SULLIVAN, Richard, J. , CHOPRA, Suman, K. , DEPIERRO, Karen , ZAIDEL, Lynette , CHRISTOPOULOU, Constantina , SUBRAMANYAM, Ravi , WU, Donghui , MORGAN, Andre, M. , SANTARPIA III, Ralph, Peter , WANG, Qin , TAMBS, Gary, Edward , KOHLI, Rajnish , BARNES, Virginia, Monsul , LEITE, Sergio , SIMON, Eric, A.
IPC: A61K8/44 , A61K8/25 , A61Q11/00 , A61K31/198 , A61P1/02
CPC classification number: A61K8/44 , A61K8/25 , A61K31/198 , A61Q11/00
Abstract: This invention relates to oral care compositions comprising a basic amino acid or salt thereof, and a small particle fraction; and to methods of using and of making these compositions.
Abstract translation: 本发明涉及包含碱性氨基酸或其盐和小颗粒级分的口腔护理组合物; 以及使用和制备这些组合物的方法。
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23.发明申请ARGININE SALTS AND THEIR USES FOR THE TREATMENT OF ILLNESSES IN THE ORAL CAVITY 审中-公开ARGININE SALTS及其用于治疗口腔溃疡的用途
公开(公告)号：WO2009099451A1
公开(公告)日：2009-08-13
申请号：PCT/US2008/058658
申请日：2008-03-28
Applicant: COLGATE-PALMOLIVE COMPANY , PRENCIPE, Michael , XU, Guofeng , SUBRAMANYAM, Ravi , WU, Donghui , CUMMINS, Diane , SULLIVAN, Richard, J. , SANTARPIA, Ralph, Peter , MELLO, Sarita, V. , ZAIDEL, Lynette , CHOPRA, Suman, K. , WANG, Qin , TAMBS, Gary, Edward , BARNES, Virginia, Monsul , MORGAN, Andre, M. , KOHLI, Rajnish , ROBINSON, Richard, Scott , LEITE, Sergio , SIMON, Eric, A.
Inventor： PRENCIPE, Michael , XU, Guofeng , SUBRAMANYAM, Ravi , WU, Donghui , CUMMINS, Diane , SULLIVAN, Richard, J. , SANTARPIA, Ralph, Peter , MELLO, Sarita, V. , ZAIDEL, Lynette , CHOPRA, Suman, K. , WANG, Qin , TAMBS, Gary, Edward , BARNES, Virginia, Monsul , MORGAN, Andre, M. , KOHLI, Rajnish , ROBINSON, Richard, Scott , LEITE, Sergio , SIMON, Eric, A.
IPC: A61K8/44 , A61Q11/00 , A61K31/198 , A61P1/02
CPC classification number: A61K8/44 , A61K8/463 , A61K8/55 , A61K8/8164 , A61K31/198 , A61Q11/00
Abstract: The invention relates to novel arginine salts, compositions comprising them, and their uses.
Abstract translation: 本发明涉及新颖的精氨酸盐，包含它们的组合物及其用途。
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公开(公告)号：WO2009045951A1
公开(公告)日：2009-04-09
申请号：PCT/US2008/078096
申请日：2008-09-29
Applicant: COLGATE-PALMOLIVE COMPANY , BOYD, Thomas, James , XU, Guofeng , SUBRAMANYAM, Ravi , VAZQUEZ, Joe
Inventor： BOYD, Thomas, James , XU, Guofeng , SUBRAMANYAM, Ravi , VAZQUEZ, Joe
Abstract: The invention includes a compound or an oral care composition comprising a compound represented by the structure (I): OH R R2 R (I) wherein R3 is selected from a hydrogen atom and a structure represented by: H m (H) wherein m is an integer of 0 to 100, R is independently selected from a first hydrocarbon structure having from 1 to 50 carbon atom and Rl and R2 are independently chosen from a hydrogen atom and a second hydrocarbon structure having 1 to 10 carbon atoms. Related methods are also disclosed.
Abstract translation: 本发明包括化合物或口腔护理组合物，其包含由结构式（I）表示的化合物：其中R 3选自氢原子的OH R R 2 R（I）和由以下表示的结构：H m（H）其中m为 0至100的整数，R独立地选自具有1至50个碳原子的第一烃结构，并且R 1和R 2独立地选自氢原子和具有1至10个碳原子的第二烃结构。 还公开了相关方法。
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公开(公告)号：WO2006071654A1
公开(公告)日：2006-07-06
申请号：PCT/US2005/046241
申请日：2005-12-21
Applicant: COLGATE-PALMOLIVE COMPANY , SUBRAMANYAM, Ravi , SREENIVASAN, Prem
Inventor： SUBRAMANYAM, Ravi , SREENIVASAN, Prem
Abstract: Antiplaque oral compositions are provided that contain an orally acceptable carrier and an antibacterial effective amount of the compound of formula (I). In various embodiments, the compositions contain from about 0.001% to about 10% by weight of the compound of formula (I).
Abstract translation: 提供了抗口腔组合物，其含有口服可接受的载体和抗菌有效量的式（I）化合物。 在各种实施方案中，组合物含有约0.001％至约10％重量的式（I）化合物。
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Patent Agency Ranking
公开(公告)号：WO2002030379A3
公开(公告)日：2002-04-18
申请号：PCT/US2001/029608
申请日：2001-09-21
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： LIU, Xiaoyan , WILLIAMS, Malcolm , SUBRAMANYAM, Ravi
IPC: A61K7/16
Abstract: An oral composition comprising in an orally acceptable vehicle, an effective antiplaque amount of an halogenated diphenyl ether or phenolic antibacterial compound, and an amount of an mixed anionic/zwitterionic surfactant system which is effective to increase the uptake of the antibacterial compound to dental tissue so as to enhance the therapeutic efficacy of the administered antibacterial compound.
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公开(公告)号：WO2017112667A1
公开(公告)日：2017-06-29
申请号：PCT/US2016/067773
申请日：2016-12-20
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： SZEWCZYK, Gregory , MANUS, Lisa , SCHAEFFER-KORBYLO, Lyndsay , POTANIN, Andrei , SUBRAMANYAM, Ravi
CPC classification number: A61K8/27 , A61K8/21 , A61K8/24 , A61K8/44 , A61K8/8176 , A61K8/8182 , A61K2800/58 , A61Q11/00 , A61Q11/02
Abstract: Disclosed herein are oral care compositions comprising a zinc amino acid halide complex, and linear polyvinylpyrrolidone and/or sodium tripolyphosphate, which compositions have improved rheological stability. Methods of making and using the compositions are also provided.
Abstract translation: 本文公开了包含锌氨基酸卤化物配合物和线性聚乙烯吡咯烷酮和/或三聚磷酸钠的口腔护理组合物，所述组合物具有改善的流变稳定性。 还提供了制造和使用该组合物的方法。
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公开(公告)号：WO2016105432A1
公开(公告)日：2016-06-30
申请号：PCT/US2014/072423
申请日：2014-12-26
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： QIAO, Baohua , PAN, Long , SZEWCZYK, Gregory , SUBRAMANYAM, Ravi
CPC classification number: A61K8/27 , A61K6/0017 , A61K6/0082 , A61K8/24 , A61K33/42 , A61K2800/58 , A61Q11/00
Abstract: An oral care composition having a soluble zinc polyphosphate complex made by combining ingredients including an inorganic zinc salt, and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the relative amount of inorganic zinc salt and long chain polyphosphates providing a phosphorus to zinc mole ratio of at least 6:1. Further provided is a method of treating a subject suffering from dentinal sensitivity applying the oral care composition to the teeth and gums of the subject.
Abstract translation: 一种具有可溶性多磷酸铜络合物的口腔护理组合物，其通过将包含无机锌盐的组合和多个具有6个或更多个磷酸酯聚合物单元的多个长链多磷酸酯组合而成，所述无机锌盐和提供磷的长链多磷酸盐的相对量 锌摩尔比至少为6:1。 还提供了一种治疗患有牙质敏感性的受试者应用口腔护理组合物到受试者的牙齿和牙龈的方法。
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公开(公告)号：WO2016105431A1
公开(公告)日：2016-06-30
申请号：PCT/US2014/072422
申请日：2014-12-26
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： NAWROCKI, Shiri , DUBOVOY, Viktor , PAN, Long , QIAO, Baohua , SZEWCZYK, Gregory , SUBRAMANYAM, Ravi
Abstract: An oral care composition having a soluble zinc polyphosphate complex made by combining ingredients including a zinc salt, a plurality of long chain polyphosphates having 6 or more phosphate polymer units, and a solvent, the relative amount of organic zinc salt and long chain polyphosphates provides a phosphorus to zinc mole ratio of at least 6:1. Further provided is a method of treating a subject suffering from dentinal sensitivity applying the oral care composition to the teeth and gums of the subject.
Abstract translation: 一种具有可溶性多磷酸铜复合物的口腔护理组合物，其通过将包含锌盐，多个具有6个或更多个磷酸酯聚合物单元的多个长链多磷酸酯和溶剂，有机锌盐和长链多磷酸盐的相对量组成的成分， 磷与锌的摩尔比至少为6:1。 还提供了一种将口腔护理组合物应用于患有牙质敏感性的受试者的牙齿和牙龈的方法。
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公开(公告)号：WO2016105430A1
公开(公告)日：2016-06-30
申请号：PCT/US2014/072421
申请日：2014-12-26
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： QIAO, Baohua , PAN, Long , SZEWCZYK, Gregory , SUBRAMANYAM, Ravi , NAWROCKI, Shiri , DUBOVOY, Viktor
Abstract: A soluble zinc polyphosphate complex made by combining ingredients which include an organic zinc salt and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the organic zinc salt and long chain polyphosphates being mixed in amounts that provide a phosphorus to zinc mole ratio of 15:1 to about 55:1. Further provided is a method of making this soluble zinc polyphosphate.
Abstract translation: 通过将包含有机锌盐和多个具有6个或更多个磷酸酯聚合物单元的多个长链多磷酸盐的成分组合而成的可溶性多磷酸锌络合物，有机锌盐和长链多磷酸盐以提供磷与锌的摩尔比 为15：1至55：1。 进一步提供制备该可溶性多磷酸锌的方法。
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