公开(公告)号：ZA926129B

公开(公告)日：1993-06-14

申请号：ZA926129

申请日：1992-08-14

Applicant: HOECHST AG

Inventor： RAPP JOCHEN ,  PAPENFUHS THEODOR

IPC: C07B61/00 ,  B01J27/122 ,  C07C227/08 ,  C07C229/56 ,  C07C

Abstract: The present invention relates to a process for the preparation of 2-amino-3-chlorobenzoic acid by dissolving 1 mol of 2,3-dichlorobenzoic acid in about 400 to about 2000 parts of water with at least the equimolar amount of an alkali metal hydroxide or with an aqueous solution of the equimolar amount of an alkali metal hydroxide, and subsequently reacting it with about 500 to about 2500 mol % of ammonia at temperatures of about 150 DEG to about 220 DEG C. in the presence of copper bronze, copper(I) salts and/or copper(II) salts.

公开(公告)号：CA1313879C

公开(公告)日：1993-02-23

申请号：CA558259

申请日：1988-02-05

Applicant: HOECHST AG

Inventor： ARNDT OTTO ,  PAPENFUHS THEODOR

IPC: C07C50/24 ,  C07C37/62 ,  C07C45/00 ,  C07C46/00 ,  C07C46/06 ,  C07C67/00

Abstract: HOE 87/F 033 of the disclosure: A process for the preparation of high-purity tetrachloro1,4-benzoquinone by the action of hydrogen peroxide and hydrochloric acid on hydroquinone, which comprises causing 3.8 to 4.2 times the molar quantity of 30 to 37% hydrochloric acid and 1.9 to 2.1 times the molar quantity of 50 to 35% hydrogen peroxide, to act at 5 to 50.degree.C on 1 mole of hydroquinone in at least 12 times the molar quantity of 30 to 37% hydrochloric acid, then heating the resulting suspension, which essentially contains 2,5dichlorohydroquinone, to 45 to 55.degree.C and again causing to act on it, at 50 to 95.degree.C, 3.8 to 4.2 times the molar quantity of 30 to 37% hydrochloric acid and 1.9 to 2.1 times the molar quantity of 50 to 35% hydrogen peroxide, in each case based on the hydroquinone used, and finally adding to the suspension, which is now essentially composed of trichloro-1,4-benzoquinone, 1.9 to 2.1 times the molar quantity of hydrochloric acid of the said concentration range, and 0.95 to 1.05 times the molar quantity of hydrogen peroxide of the said concentration range, in each case based on the hydroquinone used, at 95 to 115.degree.C, sufficiently slowly for no chlorine to escape.

公开(公告)号：CA2069140A1

公开(公告)日：1992-11-23

申请号：CA2069140

申请日：1992-05-21

Applicant: HOECHST AG

Inventor： PAPENFUHS THEODOR ,  PFIRMANN RALF

IPC: C07C51/083 ,  C07C51/377 ,  C07C51/56 ,  C07C51/567 ,  C07C63/68 ,  C07D307/89

Abstract: of the disclosure: HOE 91/F 155 Process for the preparation of 3,4,6-tetrafluorophthalic acid and the anhydride thereof Process for the preparation of 3,4,6-tetrafluorophthalic acid of the formula (1) ( 1 ) or the anhydride thereof in good yields and in an advantageous manner, by dehalogenating tetrafluorophthalic anhydride of the formula (2) (2) or tetrafluorophthalic acid in aqueous-alkaline medium using zinc at temperatures of approximately 20.degree.C to approximately 160.degree.C and, if appropriate, converting the resulting 3,4,6-trifluorophthalic acid into the anhydride in a known manner by dehydrating it.

公开(公告)号：IN171542B

公开(公告)日：1992-11-14

申请号：IN791CA1988

申请日：1988-09-22

Applicant: HOECHST AG

Inventor： PAPENFUHS THEODOR ,  GEISENBERGER JOSEF

IPC: C07C323/29 ,  B01J23/30 ,  C07B61/00 ,  C07C67/00 ,  C07C313/00 ,  C07C315/00 ,  C07C315/02 ,  C07C317/04 ,  C07C317/26 ,  C07C317/28 ,  C07C317/36 ,  C07C321/12 ,  C07C147/12

Abstract: Compounds of the formula … … in which the side chains -CH2-SO2-CH2-CH2-OH are in the ortho, meta or para position relative to one another and the amino group is in the 4-position if the two side chains are in the 1,2- or 1,3-position, are prepared by reacting 1 mol of xylylene dichloride with at least 2 mol of mercaptoethanol at 40-150 DEG C in aqueous medium in the presence of an acid-binding agent to give the corresponding compound of the formula … … which is oxidised with at least 4 mol of hydrogen peroxide at 50-120 DEG C at a pH of … this compound is converted with anhydrous sulphuric acid at 30-45 DEG C into the corresponding bissulphuric ester, the latter is nitrated with high-percentage nitric acid at 0-60 DEG C to give the bis(sulphatoethylsulphonylmethyl)nitrobenzene, which is hydrolysed after the addition of water by heating and then reduced.

公开(公告)号：ZA9201040B

公开(公告)日：1992-10-28

申请号：ZA9201040

申请日：1992-02-13

Applicant: HOECHST AG

Inventor： FOLZ GEORG ,  GEORG FOLZ ,  PAPENFUHS THEODOR ,  THEODOR PAPENFUHS

IPC: B01J27/128 ,  C07B61/00 ,  C07C303/22 ,  C07C313/04 ,  C07C315/00 ,  C07C317/14 ,  C07C

CPC classification number: C07C313/04 ,  C07C303/22 ,  C07C315/00 ,  C07C317/14 ,  C07C309/86

公开(公告)号：CA2067074A1

公开(公告)日：1992-10-26

申请号：CA2067074

申请日：1992-04-24

Applicant: HOECHST AG

Inventor： PAPENFUHS THEODOR ,  PFIRMANN RALF

IPC: C07C63/68 ,  C07C63/70 ,  C07D209/48 ,  C07C51/00

Abstract: N'-substituted N-amino-3,4,5,6-tetrafluorophthalimides, and processes for their preparation Compounds of the formula (see figure I) in which X is the radical (see figure II) where R1 and R2 are in each case a hydrogen atom, an alkyl-(C1-C10) group, aryl group, alkyl(C1-C6)-CO group or aryl-CO group, where the aryl or aryl-CO group in the case of R1 and R2 can be substituted on the aromatic ring by fluorine and/or chlorine atoms and/or alkyl(C1-C4) groups, or R1 and R2 together are a phthaloyl radical which can be substituted on the aromatic ring by 4 chlorine atoms or 4 fluorine atoms, or where X is the radical (see figure III) which can be substituted on the aromatic ring by fluorine and/or chlorine atoms and/or alkyl(C1-C4) groups, and processes for their preparation.

公开(公告)号：CA2104116A1

公开(公告)日：1992-08-15

申请号：CA2104116

申请日：1992-01-31

Applicant: HOECHST AG

Inventor： FOLZ GEORG ,  PAPENFUHS THEODOR

IPC: B01J27/128 ,  C07B61/00 ,  C07C303/22 ,  C07C313/04 ,  C07C315/00 ,  C07C317/14

Abstract: Process for the preparation of 4-alkylsulfonyl-1-alkyl-2-chlorobenzenes and like compounds.A process for the preparation of 4-alkyl(C1-C4)-sulfonyl-1-alkyl-2-chlorobenzenes, in very good yields and with high selectivity by selectively chlorinating a p-alkyl-benzenesulfonyl chloride with gaseous chlorine in the presence of a chlorine carrier at 50° C. to 100° C. to give a compound of the formulain which R1 is an alkyl (C1-C4) group, subsequently reducing the latter in an aqueous medium at a pH of 8 to 10 with sodium hydrogen sulfite or sodium sulfite at 40 to 90° C. to give a compound of the formulaand reacting the latter with alkyl(C1-C4) chloride in the presence of an acid binder at 80 to 150° C., and also compounds of the last mentioned formula which, instead of the -SO2Na group contain the -SO2X group (X=hydrogen atom or alkali metal atom).

公开(公告)号：IN168810B

公开(公告)日：1991-06-08

申请号：IN808CA1988

申请日：1988-09-29

Applicant: HOECHST AG

Inventor： PAPENFUHS THEODOR

IPC: C07C313/00 ,  C07C67/00 ,  C07C315/02 ,  C07C317/14 ,  C07C317/44 ,  C07C317/48 ,  C09B62/507 ,  C07C79/36 ,  C07C101/42

Abstract: Compounds of the formula (5) … … in which R denotes a hydrogen or oxygen atom and the group -N(R)2 and the hydroxyethylsulphonyl group are in the ortho or para position relative to one another, are prepared by converting 1 mol of a halonitrobenzoic acid of the formula (2) … … in which X represents a fluorine, chlorine, bromine or iodine atom and the nitro group and the halogen atom are in the ortho or para position relative to one another, with at least 1 mol of mercaptoethanol in aqueous solution or suspension or in an organic solvent in the presence of an acid-binding agent at about 20 to about 100 DEG C into the hydroxyethylmercaptonitrobenzoic acids of the formula (3) … … oxidising these acids in a manner known per se to the corresponding hydroxyethylsulphonylnitrobenzoic acids of the formula (5) (R = O) mentioned and, if desired, reducing the latter in a manner known per se to the hydroxyethylsulphonylaminobenzoic acids of the formula (4) … … in which the amino and hydroxyethylsulphonyl groups are in the ortho or para position relative to one another.

公开(公告)号：CA2031444A1

公开(公告)日：1991-06-06

申请号：CA2031444

申请日：1990-12-04

Applicant: HOECHST AG

Inventor： PAPENFUHS THEODOR ,  SCHUBERT HANS ,  HESS REINER

IPC: B01J27/232 ,  C07B61/00 ,  C07C41/01 ,  C07C41/16 ,  C07C43/16 ,  C07C43/29 ,  C07C41/06

Abstract: HOE 89/F 383 Process for the preparation of 3,4'-dichlorodiphenyl ether A process for the preparation of 3,4'-dichlorodiphenyl ether from 1,3-dichlorobenzene and 4-chlorophenol, which comprises mixing 1 mol of 4-chlorophenol with about 2 to about 6 mol of initially introduced 1,3-dichlorobenzene and about 1 to about 3 mol of potassium carbonate in about 1 to about 5 mol of a dipolar aprotic solubilizer which boils above l60.degree.C, at temperatures of about 160.degree.C to about 190.degree.C with stirring, then adding about 0.0l to about 1 mol-% of basic copper carbonate of the formula Cu(OH)2?CuCO3?0.5 H2O and heating with stirring to about 170 to about 173.degree.C while removing the water formed by distillation, then optionally adding further 4-chloxo-phenol with the proviso that from the start the amount of 1,3-dichlorobenzene present in terms of moles is always 1 to 3 mol greater than the totally added amount of 4-chlorophenol and, if desired, additionally adding basic copper carbonate of the formula mentioned if at the start less than 0.1 mol-% had been added, additionally stirring within the last-mentioned temperature range and finally working up after allowing to cool.

公开(公告)号：IN162546B

公开(公告)日：1988-06-11

申请号：IN809CA1984

申请日：1984-11-26

Applicant: HOECHST AG

Inventor： PAPENFUHS THEODOR

IPC: C07C315/04 ,  C07C67/00 ,  C07C313/00 ,  C07C315/02 ,  C07C317/36 ,  C07C91/44

Abstract: Process for the preparation of 5-hydroxyethylsulfonyl-2-aminophenol (ethers) of the formula (I) (I) wherein R denotes a hydrogen atom or a C1-C4-alkyl group and R1 denotes a hydrogen atom or an alkyl or alkoxy group with in each case 1-4 carbon atoms, which comprises condensing 5-chloro(or bromo)-2-nitrophenols, or alkyl ethers thereof, of the formula (II) (II) in which R and R1 have the abovementioned meanings and X denotes a chlorine or bromine atom, with thioglycol to give 2-nitrophenol(ether) 5-hydroxyethyl-sulfides of the formula (III) (III) wherein R and R1 have the abovementioned meanings, oxidizing these to give 5-hydroxyethylsulfonyl-2-nitrophenol (ethers) (IV) and reducing the latter to give compounds of the above formula (I).