公开(公告)号：GB2499933B

公开(公告)日：2017-03-08

申请号：GB201308835

申请日：2011-10-18

Applicant: IBM

Inventor： EMMANUEL DELAMARCHE ,  GOVIND KAIGALA ,  ROBERT LOVCHIK

IPC: B01L3/00

公开(公告)号：GB2608770B

公开(公告)日：2025-05-14

申请号：GB202215280

申请日：2021-02-15

Applicant: IBM

Inventor： ROBERT DEAN LOVCHIK ,  JONAS WEISS ,  YUKSEL TEMIZ ,  EMMANUEL DELAMARCHE

IPC: G07D7/20 ,  B42D25/30 ,  G06K19/06 ,  G07D7/12 ,  G09F3/02

Abstract: Technology for managing objects. A method is applied to a set of objects, for example, in view of commissioning such objects. The method includes patterning a surface of each object of a set of objects to be managed. The patterning is accomplished by using hard particles to make indentations in a surface of each object of the set of object, with the pattern formed on each object being a unique physical fingerprint that can be used to identify the object when performing various manage method(s) on the objects.

公开(公告)号：GB2577225B

公开(公告)日：2021-08-11

申请号：GB201918101

申请日：2018-06-20

Applicant: IBM

Inventor： ONUR GOEKCE ,  EMMANUEL DELAMARCHE

IPC: B01L3/00

Abstract: A method for optically reading information encoded in a microfluidic device, the microfluidic device including an input microchannel, microfluidic modules, and sets of nodes. Nodes of a first set connect the input microchannel to one of the microfluidic modules, and nodes of a second set connect the one of the microfluidic modules to another to form an ordered pair of the microfluidic modules, where the nodes of the first and second sets have different liquid pinning strengths. A liquid loaded into the input microchannel causes an ordered passage of the liquid through each of the microfluidic modules in an order determined by the liquid pinning strengths of the nodes. The passage of the liquid produces an optically readable dynamic pattern which evolves in accordance with the ordered passage of the liquid through the device.

公开(公告)号：GB2548941B

公开(公告)日：2020-08-19

申请号：GB201617833

申请日：2015-03-04

Applicant: IBM

Inventor： EMMANUEL DELAMARCHE ,  YUKSEL TEMIZ

IPC: B01L3/00 ,  G01N33/53 ,  G01N33/543 ,  G01N33/554 ,  H01L21/00

Abstract: A microfluidic chip (100) comprises a layer (10, 60) with an array (30) of bead trapping cavities (20) provided in that layer (10, 60), wherein each of the cavities (20) has a conic shape, defined by one or more lateral walls (21-24) that are, each, hydrophilic, and wherein each of the cavities (20) extends as a blind hole in the thickness of said layer (10, 60). Methods of fabrication of such a chip are further provided.

公开(公告)号：GB2581291A

公开(公告)日：2020-08-12

申请号：GB202006022

申请日：2018-09-13

Applicant: IBM

Inventor： YUKSEL TEMIZ ,  EMMANUEL DELAMARCHE ,  SUFI ZAFAR

IPC: G01N27/26

Abstract: The invention is notably directed to a microfluidic device. The device comprises a substrate with a microchannel formed as a groove on a main surface of the substrate. The device further comprises one or more conduits extending parallel to the main surface of the substrate, and from a lateral surface of the substrate up to a lateral wall of the microchannel. The one or more conduits are configured so as to allow insertion of one or more electrodes therein, respectively, and such that an end of each of the one or more electrodes can reach into the microchannel. The invention is further directed to related sets of components, which include the above microfluidic device, as well as a housing, with electronics, and, possibly, a porous support (e.g., a membrane) and a cap. Biosensing applications are notably contemplated. The invention is further directed to methods of operating a microfluidic device.

公开(公告)号：GB2578977A

公开(公告)日：2020-06-03

申请号：GB202000287

申请日：2018-06-20

Applicant: IBM

Inventor： EMMANUEL DELAMARCHE ,  ONUR GOEKCE

IPC: B03B5/60 ,  B01L3/00 ,  F16K99/00

Abstract: The invention is directed to a microfluidic device. The device includes an input microchannel, a set of m distribution microchannels, a set of m microfluidic modules and a set of m nodes. The m microfluidic modules (m ≥ 2) are in fluidic communication with the m distribution microchannels, respectively. The one or more nodes of the set of m nodes branch from the input microchannel, and further branch to a respective one of the set of m distribution microchannels. In addition, a subset, but not all, of the nodes are altered. The nodes of the set of m nodes have different liquid pinning strengths. As a result, the extent in which a liquid passes through one or more of the m microfluidic modules varies based on the different liquid pinning strengths, in operation. Additional sets of nodes may be provided to allow liquid to pass through ordered pairs of modules.

公开(公告)号：GB2577225A

公开(公告)日：2020-03-18

申请号：GB201918101

申请日：2018-06-20

Applicant: IBM

Inventor： ONUR GOEKCE ,  EMMANUEL DELAMARCHE

IPC: B01L3/00

Abstract: A method for optically reading information encoded in a microfluidic device, the microfluidic device including an input microchannel, microfluidic modules, and sets of nodes. Nodes of a first set connect the input microchannel to one of the microfluidic modules, and nodes of a second set connect the one of the microfluidic modules to another to form an ordered pair of the microfluidic modules, where the nodes of the first and second sets have different liquid pinning strengths. A liquid loaded into the input microchannel causes an ordered passage of the liquid through each of the microfluidic modules in an order determined by the liquid pinning strengths of the nodes. The passage of the liquid produces an optically readable dynamic pattern which evolves in accordance with the ordered passage of the liquid through the device.

公开(公告)号：GB2555949A

公开(公告)日：2018-05-16

申请号：GB201716508

申请日：2015-06-15

Applicant: IBM

Inventor： ONUR GOEKCE ,  EMMANUEL DELAMARCHE

IPC: B01L3/00 ,  B01F13/00 ,  B01F13/10

Abstract: A microfluidic device (1) comprises a set of one or more microchannels (10) each comprising: a microchannel portion (12) with a longitudinal liquid barrier (20) extending longitudinally therein, thereby defining a first region (121) and a second region (122) in the microchannel portion (12); one or more first liquid passages (22), at the level of the longitudinal barrier (20); a liquid inlet (11), configured to allow liquid to enter the first region (121); a liquid outlet (13), configured to allow liquid to leave the microchannel portion (12); a transversal liquid barrier (30) arranged between the microchannel portion (12) and the liquid outlet (13) to hold liquid flowed from the liquid inlet (11) in the first region (121), in operation; and one or more second liquid passages (32) at the level of transversal liquid barrier (30), the device further comprising liquid pumping means (15) configured to displace liquid through each microchannel portion (12) of the set of one or more microchannels (10), wherein, the one or more first liquid passages (22) are configured so as to allow, in operation, excess liquid in the first region (121) to flow into the second region (122), transversally to the longitudinal barrier (20), and the one or more second liquid passages (32) are configured so as to allow, in operation, excess liquid in the longitudinal portion (12) to be discharged via the liquid outlet (13). A method for controlling liquid in the microfluidic device (1) is also provided.

公开(公告)号：GB2553713A

公开(公告)日：2018-03-14

申请号：GB201716704

申请日：2016-03-16

Applicant: IBM

Inventor： EMMANUEL DELAMARCHE ,  YUKSEL TEMIZ

IPC: B01L3/00

Abstract: Amicrofluidic device and method for fabrication includes a microfluidic channel that has a closed portion, which comprises: a liquid pathway formed by a wetting area; and an anti- wetting area extending along and contiguously with the liquid pathway. The anti-wetting area is configured so as to provide a vent to evacuate gas along the anti-wetting area.

公开(公告)号：GB2553675A

公开(公告)日：2018-03-14

申请号：GB201713688

申请日：2016-02-12

Applicant: IBM

Inventor： JULIEN AUTEBERT ,  EMMANUEL DELAMARCHE ,  GOVIND KAIGALA ,  ADITYA KASHYAP ,  XANDER FRANK VAN KOOTEN

IPC: B01L3/00 ,  B01L3/02 ,  G01N35/08

Abstract: A microfluidic probe head for providing a sequence of separate liquid volumes separated by spacers, the separate liquid volumes comprising a respective target substance associated with a respective target area, the microfluidic probe head comprising: an inlet and an outlet, a first fluid channel fluidly connected to the inlet, the first fluid channel being configured for delivering an injection liquid from the inlet to a respective target area, the respective target area being covered by an immersion liquid and comprising a respective target substance, a second fluid channel fluidly connected to the outlet, the second fluid channel being configured for delivering liquid volumes from the respective target area to the outlet, each liquid volume including at least some of the injection liquid, at least some of the immersion liquid and a respective target substance, and a spacer insertion unit fluidly connected to the second fluid channel, the spacer insertion unit being configured for inserting spacers into the second fluid channel between the liquid volumes to thereby provide the sequence of separate liquid volumes separated by spacers.