公开(公告)号：DE69831950T2

公开(公告)日：2006-07-20

申请号：DE69831950

申请日：1998-06-25

Applicant: KANEKA CORP

Inventor： YOKOTA SHIN-ICHI ,  YAMAMOTO KOZO ,  MORIKAWA SOUICHI ,  FUSE YOSHIHIDE ,  KITAHARA MIKIO

IPC: C07D405/06 ,  A61K31/40 ,  A61K31/445

Abstract: A disease treatment is provided by controlling the expression of a protein induced by a heat shock factor. The novel compound benzo-1,3-dioxole provides an inhibitor of HSF activity or an inhibitor of inducing the production of a protein regulated by HSF, which inhibits the activity of a heat shock factor, a transcriptional regulatory factor, thereby in turn inhibiting transcription of a structural gene having a heat shock element sequence in the gene region for transcriptional regulation into RNA, and thus inhibiting translation of the gene into a protein, and resulting in inhibition of inducing production of RNA or protein encoded by the gene. It also provides a drug for treating or preventing cancer through thermotherapy and a drug for treating or preventing stress diseases such as depression.

公开(公告)号：DK1350516T3

公开(公告)日：2006-01-09

申请号：DK01270339

申请日：2001-12-12

Applicant: KANEKA CORP

Inventor： MAE TATSUMASA ,  TSUKAGAWA MISUZU ,  KISHIDA HIDEYUKI ,  KITANO MITSUAKI ,  KITAHARA MIKIO ,  NAKAGAWA KAKU

IPC: A21D2/36 ,  A21D13/08 ,  A23L2/00 ,  A23L7/109 ,  A23L27/10 ,  A23L27/60 ,  A23L33/115 ,  A23L33/15 ,  A61K8/97 ,  A61K33/06 ,  A61K36/00 ,  A61K36/48 ,  A61K36/484 ,  A61K36/54 ,  A61K36/61 ,  A61K36/9066 ,  A61P3/04 ,  A61P3/06 ,  A61P3/10 ,  A61P9/12 ,  A61Q19/06

Abstract: The invention aims at a composition for preventing or ameliorating multiple risk factor syndrome involving visceral fat-type obesity, diabetes mellitus, hyperlipemia and hypertension, which comprises at least one member selected from the group consisting of a licorice hydrophobic extract, a turmeric extract, a clove extract, and a cinnamon extract.

公开(公告)号：DE60115094D1

公开(公告)日：2005-12-22

申请号：DE60115094

申请日：2001-12-12

Applicant: KANEKA CORP

Inventor： MAE TATSUMASA ,  TSUKAGAWA MISUZU ,  KISHIDA HIDEYUKI ,  KITANO MITSUAKI ,  KITAHARA MIKIO ,  NAKAGAWA KAKU

IPC: A21D2/36 ,  A23L7/109 ,  A23L27/10 ,  A23L27/60 ,  A23L33/115 ,  A23L33/15 ,  A61K8/97 ,  A61K33/06 ,  A61K36/00 ,  A61K36/48 ,  A61K36/484 ,  A61K36/54 ,  A61K36/61 ,  A61K36/9066 ,  A61P3/04 ,  A61P3/06 ,  A61P3/10 ,  A61P9/12 ,  A61Q19/06 ,  A61K35/78

Abstract: The invention aims at a composition for preventing or ameliorating multiple risk factor syndrome involving visceral fat-type obesity, diabetes mellitus, hyperlipemia and hypertension, which comprises at least one member selected from the group consisting of a licorice hydrophobic extract, a turmeric extract, a clove extract, and a cinnamon extract.

公开(公告)号：NO20041921A

公开(公告)日：2004-07-06

申请号：NO20041921

申请日：2004-05-10

Applicant: KANEKA CORP

Inventor： UEDA YASUYOSHI ,  MAE TATSUMASA ,  TSUKAGAWA MISUZU ,  KITAHARA MIKIO ,  NAKAGAWA KAKU ,  KITAMURA SHIRO ,  SAHIDA YUTAKA ,  KURODA MINPEI ,  MIMAKI YOSHIHIRO

IPC: A23K1/16 ,  A23K1/18 ,  A23L1/30 ,  A61K31/12 ,  A61K31/353 ,  A61K31/366 ,  A61K31/37 ,  A61K36/00 ,  A61K36/484 ,  A61P3/04 ,  A61P3/06 ,  A61P3/10 ,  A61P9/10 ,  A61P9/12 ,  A61P37/02 ,  A61P43/00 ,  C07D311/06 ,  C07D311/18 ,  C07D311/30 ,  C07D311/36 ,  C07D311/38 ,  C07D311/58 ,  C07D493/04 ,  A61K35/78

CPC classification number: C07D311/06 ,  A23K20/111 ,  A23K20/121 ,  A23K50/00 ,  A23K50/40 ,  A23L33/10 ,  A23L33/105 ,  A61K31/12 ,  A61K31/353 ,  A61K31/37 ,  A61K36/484 ,  A61K2300/00

公开(公告)号：AT309815T

公开(公告)日：2005-12-15

申请号：AT01270339

申请日：2001-12-12

Applicant: KANEKA CORP

Inventor： MAE TATSUMASA ,  TSUKAGAWA MISUZU ,  KISHIDA HIDEYUKI ,  KITANO MITSUAKI ,  KITAHARA MIKIO ,  NAKAGAWA KAKU

IPC: A21D2/36 ,  A23L7/109 ,  A23L27/10 ,  A23L27/60 ,  A23L33/115 ,  A23L33/15 ,  A61K8/97 ,  A61K33/06 ,  A61K36/00 ,  A61K36/48 ,  A61K36/484 ,  A61K36/54 ,  A61K36/61 ,  A61K36/9066 ,  A61P3/04 ,  A61P3/06 ,  A61P3/10 ,  A61P9/12 ,  A61Q19/06 ,  A61K35/78

Abstract: The invention aims at a composition for preventing or ameliorating multiple risk factor syndrome involving visceral fat-type obesity, diabetes mellitus, hyperlipemia and hypertension, which comprises at least one member selected from the group consisting of a licorice hydrophobic extract, a turmeric extract, a clove extract, and a cinnamon extract.

公开(公告)号：NO20041921L

公开(公告)日：2004-07-06

申请号：NO20041921

申请日：2004-05-10

Applicant: KANEKA CORP

Inventor： UEDA YASUYOSHI ,  MAE TATSUMASA ,  TSUKAGAWA MISUZU ,  KITAHARA MIKIO ,  NAKAGAWA KAKU ,  KITAMURA SHIRO ,  SAHIDA YUTAKA ,  KURODA MINPEI ,  MIMAKI YOSHIHIRO

IPC: A23K1/16 ,  A23K1/18 ,  A23L1/30 ,  A61K31/12 ,  A61K31/353 ,  A61K31/366 ,  A61K31/37 ,  A61K36/00 ,  A61K36/484 ,  A61P3/04 ,  A61P3/06 ,  A61P3/10 ,  A61P9/10 ,  A61P9/12 ,  A61P37/02 ,  A61P43/00 ,  C07D311/06 ,  C07D311/18 ,  C07D311/30 ,  C07D311/36 ,  C07D311/38 ,  C07D311/58 ,  C07D493/04 ,  A61K35/78

Abstract: The present invention easily and efficiently provides a peroxisome proliferator-activated receptor ligand, and a composition for amelioration of insulin resistance or for prevention and/or amelioration of the insulin resistance syndrome containing the same, as an active ingredient. The present invention relates to a peroxisome proliferator-activated receptor ligand which comprises a prenylflavonoid, a chalcone derivative exclusive of prenylflavonoids, a flavonol derivative exclusive of prenylflavonoids, and a salt, a glycoside and/or an esterified substance thereof acceptable as a pharmaceutical preparation or a food or a beverage; a composition containing the above ligand; a plant-derived extract containing the above ligand; and a process for producing the above extract.

公开(公告)号：AU2003236371A1

公开(公告)日：2003-10-20

申请号：AU2003236371

申请日：2003-04-04

Applicant: KANEKA CORP

Inventor： IKEHARA TOSHINORI ,  KITAHARA MIKIO

IPC: A23D9/00 ,  A23L1/30 ,  A23L27/10 ,  A61K36/484 ,  A61P1/06 ,  A61P11/10 ,  A61P25/04 ,  A61K35/78 ,  A61K47/14

Abstract: Method of making a lipid composition containing Glycyrrhiza hydrophobic components comprises extracting the plant with a lipid solvent (L) containing at least 10 wt.% lipid soluble polyhydric alcohol fatty acid ester(s) (FAE). Independent claims are also included for: (a) a composition obtained by the method; and (b) a lipid foodstuff containing the composition.

公开(公告)号：AU2260302A

公开(公告)日：2002-06-24

申请号：AU2260302

申请日：2001-12-12

Applicant: KANEKA CORP

Inventor： MAE TATSUMASA ,  TSUKAGAWA MISUZU ,  KISHIDA HIDEYUKI ,  KITANO MITSUAKI ,  KITAHARA MIKIO ,  NAKAGAWA KAKU

IPC: A21D2/36 ,  A23L7/109 ,  A23L27/10 ,  A23L27/60 ,  A23L33/115 ,  A23L33/15 ,  A61K8/97 ,  A61K33/06 ,  A61K36/00 ,  A61K36/48 ,  A61K36/484 ,  A61K36/54 ,  A61K36/61 ,  A61K36/9066 ,  A61P3/04 ,  A61P3/06 ,  A61P3/10 ,  A61P9/12 ,  A61Q19/06 ,  A61K35/78 ,  A61K7/00 ,  A61K7/50 ,  A23L1/30 ,  A23L1/16 ,  A23L2/00 ,  A21D13/08

Abstract: The invention aims at a composition for preventing or ameliorating multiple risk factor syndrome involving visceral fat-type obesity, diabetes mellitus, hyperlipemia and hypertension, which comprises at least one member selected from the group consisting of a licorice hydrophobic extract, a turmeric extract, a clove extract, and a cinnamon extract.

公开(公告)号：AU7933298A

公开(公告)日：1999-01-19

申请号：AU7933298

申请日：1998-06-25

Applicant: KANEKA CORP

Inventor： YOKOTA SHINICHI ,  YAMAMOTO KOZO ,  MORIKAWA SOUICHI ,  FUSE YOSHIHIDE ,  KITAHARA MIKIO

IPC: C07D405/06 ,  A61K31/40 ,  A61K31/445

Abstract: A disease treatment is provided by controlling the expression of a protein induced by a heat shock factor. The novel compound benzo-1,3-dioxole provides an inhibitor of HSF activity or an inhibitor of inducing the production of a protein regulated by HSF, which inhibits the activity of a heat shock factor, a transcriptional regulatory factor, thereby in turn inhibiting transcription of a structural gene having a heat shock element sequence in the gene region for transcriptional regulation into RNA, and thus inhibiting translation of the gene into a protein, and resulting in inhibition of inducing production of RNA or protein encoded by the gene. It also provides a drug for treating or preventing cancer through thermotherapy and a drug for treating or preventing stress diseases such as depression.

公开(公告)号：EP1491204A4

公开(公告)日：2005-09-14

申请号：EP03745912

申请日：2003-04-04

Applicant: KANEKA CORP

Inventor： IKEHARA TOSHINORI ,  KITAHARA MIKIO

IPC: A23D9/00 ,  A23L1/221 ,  A23L1/30 ,  A61K36/484 ,  A61P1/06 ,  A61P11/10 ,  A61P25/04 ,  A61K35/78 ,  A61K47/14

CPC classification number: A61K36/484 ,  A23L27/11 ,  A23L33/105 ,  A23L33/12 ,  A61K2300/00

Abstract: A fat solvent containing 10% by weight or more of a specific fat-soluble polyhydric alcohol fatty acid ester, in particular, a glycerol fatty acid ester is used as a solvent for extracting hydrophobic components of glycyrrhiza. Thus, the hydrophobic components of glycyrrhiza having excellent effects as foods and drinks such as health foods, foods with health claims (foods for specified health uses, foods with nutrient function claims), medicines, etc. can be produced at a reduced cost and the thus obtained compositions have elevated stability and improved handling properties.