公开(公告)号：DE102004011770B4

公开(公告)日：2005-12-15

申请号：DE102004011770

申请日：2004-03-09

Applicant: LEICA MICROSYSTEMS

Inventor： MOELLMANN KYRA ,  HOFFMANN JUERGEN

IPC: G02B21/00 ,  G02B21/06

Abstract: Scanning microscope comprises a beam deflection device (1) that deflects a first illuminating light beam (5) to scan a sample (13), and a second beam deflection device (33) that deflects a second illuminating light beam (37). The first and the second beam deflection device deflect the second illuminating light beam. - An INDEPENDENT CLAIM is also included for a module comprising a second beam deflection device for coupling to a scanning microscope with a first beam deflection device. Preferred Features: The first and the second beam deflection devices are synchronized with each other.

公开(公告)号：DE10331906B4

公开(公告)日：2005-06-16

申请号：DE10331906

申请日：2003-07-15

Applicant: LEICA MICROSYSTEMS

Inventor： MOELLMANN KYRA

IPC: G02B6/42 ,  G02B21/00 ,  G02B21/06 ,  G02B6/02

Abstract: A light source with a microstructured optical element which spectrally diffuses the light from a primary source, comprises a lens which focusses the spectrally-diffused light to give an illumination light beam. The lens compensates for the varying divergences of the spectral components of the spectrally diffused light. The invention further relates to a microscope.

公开(公告)号：DE10115488A1

公开(公告)日：2001-12-20

申请号：DE10115488

申请日：2001-03-29

Applicant: LEICA MICROSYSTEMS

Inventor： STORZ RAFAEL ,  ENGELHARDT JOHANN ,  MOELLMANN KYRA

IPC: G02B6/00 ,  G02B5/00 ,  G02B5/04 ,  G02B5/18 ,  G02B5/22 ,  G02B6/02 ,  G02B6/12 ,  G02B6/122 ,  G02B6/255 ,  G02B21/00 ,  G02B21/06 ,  G02B27/00 ,  G02F1/39 ,  H01S3/00 ,  H01S3/16 ,  G02F2/02 ,  G02B23/24 ,  G03F7/20 ,  G02F1/11

Abstract: The arrangement has a scanning microscope and contains a laser (10 and an optical arrangement (12) that forms an image of the light from the laser onto the specimen (13) under investigation. An optical component (3) is arranged between the laser and the optical arrangement to spectrally expand the laser light during a single pass through. Independent claims are also included for the following: a scanning microscope and an illumination arrangement for a scanning microscope.

公开(公告)号：AT422246T

公开(公告)日：2009-02-15

申请号：AT04766844

申请日：2004-09-23

Applicant: LEICA MICROSYSTEMS

Inventor： ULRICH HEINRICH ,  KNEBEL WERNER ,  MOELLMANN KYRA ,  EUTENEUER PETER

IPC: G02B21/00 ,  G02B21/06 ,  G02B21/08

Abstract: A microscope comprises an objective and a light source that produces an illumination light beam-in particular for evanescent illumination of a sample, which exhibits a focus in the plane of the objective pupil. To adjust the penetration depth, an adjustment mechanism is provided with which the spatial position of the focus within the plane of the objective pupil may be changed.

公开(公告)号：DE10142229B4

公开(公告)日：2007-02-01

申请号：DE10142229

申请日：2001-08-29

Applicant: LEICA MICROSYSTEMS

Inventor： ENGELHARDT JOHANN ,  MOELLMANN KYRA

IPC: G02B21/24

Abstract: A microscope includes a lens holder for receiving a lens. A locking device is provided that affixes the received lens so that the lens cannot be removed without authorization.

公开(公告)号：DE10344410A1

公开(公告)日：2005-04-28

申请号：DE10344410

申请日：2003-09-25

Applicant: LEICA MICROSYSTEMS

Inventor： ULRICH HEINRICH ,  KNEBEL WERNER ,  MOELLMANN KYRA

IPC: G02B21/00 ,  G02B21/02 ,  G02B21/06 ,  G02B21/08 ,  G02B21/32

Abstract: A scanning microscope includes a light source for evanescently illuminating a sample disposed on a slide. A point detector receives detection light emanating from a scanning point of the sample. A beam deflection device disposed in an optical path of the detection light can shift a position of the scanning point.

公开(公告)号：DE10321829A1

公开(公告)日：2004-12-16

申请号：DE10321829

申请日：2003-05-14

Applicant: LEICA MICROSYSTEMS

Inventor： MOELLMANN KYRA ,  HOFFMANN JUERGEN

IPC: G02B7/182 ,  G02B26/10

Abstract: The beam deflector has two tilting mirrors (3,4) each carried on a shaft (1,2). The axes of rotation of the mirrors are essentially parallel to each other. The shafts (1,2) are mechanically coupled for rotation of the mirrors such that the mirrors rotate a different angles to each other in a predetermined angular relationship. Preferably the two shafts have a common drive such that one driven shaft drives the other.

公开(公告)号：DE10302259B3

公开(公告)日：2004-06-03

申请号：DE10302259

申请日：2003-01-22

Applicant: LEICA MICROSYSTEMS

Inventor： KNEBEL WERNER ,  STORZ RAFAEL ,  MOELLMANN KYRA

IPC: G02B21/00 ,  G02F1/11 ,  G02F1/13

Abstract: The microscope has an acousto-optical component (13) positioned in the path of the output beam (7) from an illumination light source (3) and the detection light (31) from the illuminated sample received by a detector (41). The acousto-optical component allows a partial beam extracted from the illumination beam to be fed to a monitoring detector (49), connected in a regulation circuit (51) for regulating the intensity of the illumination light (17).

公开(公告)号：DE10251345A1

公开(公告)日：2004-05-19

申请号：DE10251345

申请日：2002-11-05

Applicant: LEICA MICROSYSTEMS

Inventor： HOPPE MARTIN ,  KNEBEL WERNER ,  MOELLMANN KYRA ,  STORZ RAFAEL

IPC: G02B21/24 ,  A61B5/00 ,  A61B5/02

Abstract: The invention concerns a method and an apparatus for investigating layers ( 1 ) of tissues in living animals using a microscope ( 2 ). The microscope ( 2 ) is focused onto a layer ( 1 ), and images of the layer ( 1 ) are acquired or optical measurements are performed on it. Positional changes of the layer ( 1 ) are brought about by movements of the animal or of its organs. The positional changes are sensed, and corresponding signals are generated. The signals are stored, together with the corresponding images or measurement results, for later evaluation; or they are processed in such a way that the positional changes are compensated for in order to investigate the layer ( 1 ). As a result, the layer ( 1 ) can be qualitatively or quantitatively investigated microscopically, irrespective of the movement of the animal or its organs.

公开(公告)号：DE10206980A1

公开(公告)日：2003-08-21

申请号：DE10206980

申请日：2002-02-20

Applicant: LEICA MICROSYSTEMS

Inventor： MOELLMANN KYRA

IPC: G02B21/00 ,  G02B21/06

Abstract: A microscope having a light source that emits light pulses for illumination of a specimen, the light pulses containing photons having a photon energy, is disclosed. The microscope is characterized in that a detector, which has an energy band gap between a quiescent state and an active state that is greater than the photon energy, is provided for determination of a time-defined pulse width of the light pulses. Also described are a detector for determination of a time-defined pulse width of light pulses for illumination of a microscopic specimen, and a method for microscopy.