SEM repair for sub-optimal features
    351.
    发明授权
    SEM repair for sub-optimal features 失效
    SEM修复次优特征

    公开(公告)号:US08211717B1

    公开(公告)日:2012-07-03

    申请号:US13013947

    申请日:2011-01-26

    Abstract: A method and system for repairing photomasks is disclosed. A scanning electron microscope (SEM) is used to identify, measure, and correct defects. The SEM is operated in multiple modes, including a measuring mode and a repair mode. The repair mode is of higher landing energy and exposure time than the measuring mode, and induces shrinkage in the photoresist to correct various features, such as vias that are too small.

    Abstract translation: 公开了一种修复光掩模的方法和系统。 扫描电子显微镜(SEM)用于识别,测量和纠正缺陷。 SEM以多种模式运行,包括测量模式和修复模式。 修复模式比测量模式具有更高的着陆能量和曝光时间,并且在光致抗蚀剂中引起收缩以校正诸如过小的通孔等各种特征。

    Excitatory glycine receptors and methods
    352.
    发明授权
    Excitatory glycine receptors and methods 失效
    兴奋性甘氨酸受体和方法

    公开(公告)号:US08193315B2

    公开(公告)日:2012-06-05

    申请号:US12842974

    申请日:2010-07-23

    CPC classification number: C07K14/70571 C07H21/04

    Abstract: The invention provides isolated N-methyl-D-aspartate type 3B (NR3B) polypeptides, functional fragments and peptides, encoding nucleic acid molecules and polynucleotides, and specific antibodies. Also provided are excitatory glycine receptors, containing either NR3B or NR3A polypeptides. Further provided are methods for detecting excitatory glycine receptor ligands, agonists and antagonists. The invention also provides related diagnostic and therapeutic methods.

    Abstract translation: 本发明提供分离的N-甲基-D-天冬氨酸3B型(NR3B)多肽,功能片段和肽,编码核酸分子和多核苷酸以及特异性抗体。 还提供了含有NR3B或NR3A多肽的兴奋性甘氨酸受体。 还提供了检测兴奋性甘氨酸受体配体,激动剂和拮抗剂的方法。 本发明还提供了相关的诊断和治疗方法。

    TREATMENT OF INSULIN RESISTANCE/METABOLIC SYNDROME TO ALLEVIATE THE RISKS OF DEMENTIA
    355.
    发明申请
    TREATMENT OF INSULIN RESISTANCE/METABOLIC SYNDROME TO ALLEVIATE THE RISKS OF DEMENTIA 审中-公开
    治疗胰岛素抵抗/代谢综合症以克服DEMENTIA的风险

    公开(公告)号:US20110293556A1

    公开(公告)日:2011-12-01

    申请号:US13205534

    申请日:2011-08-08

    CPC classification number: A61K38/31

    Abstract: This invention relates to Applicant's discovery that Metabolic Syndrome , a cluster of disorders stemming from a resistance to insulin, contributes directly to dementia, particularly Alzheimer's disease. Applicant's invention includes a screening method to determine susceptibility and diagnosis of dementia based on the risk factors for Metabolic Syndrome. Applicant's invention further includes methods for the prevention or treatment of dementia and other neurological conditions based on (1) minimizing insulin resistance, thereby preventing excess biosynthesis of insulin; (2) modulating the activity of IDE such that insulin competes less efficiently with β-amyloid protein for the TDE; and (3) blocking the consequences of NMDA receptor activation, such as by minimizing the generation of NO and other harmful free radicals.

    Abstract translation: 本发明涉及申请人的发现,代谢综合症是由抗胰岛素引起的一系列疾病,直接导致痴呆,特别是阿尔茨海默氏病。 申请人的发明包括基于代谢综合征的危险因素确定痴呆的易感性和诊断的筛选方法。 申请人的发明还包括基于(1)使胰岛素抵抗最小化从而防止胰岛素过量生物合成来预防或治疗痴呆和其他神经病症的方法; (2)调节IDE的活性,使得胰岛素与TDE的β-淀粉样蛋白相比较有效地竞争; 和(3)阻止NMDA受体活化的后果,例如通过最小化NO和其他有害自由基的产生。

    WEAR PAD ADJUSTMENT ASSEMBLY
    356.
    发明申请
    WEAR PAD ADJUSTMENT ASSEMBLY 有权
    磨损调整组件

    公开(公告)号:US20110222801A1

    公开(公告)日:2011-09-15

    申请号:US12720326

    申请日:2010-03-09

    CPC classification number: F16B5/0225 F16C29/02 F16C29/12

    Abstract: A cam assembly is provided for adjustment of a drill feed guide wear pad. The cam assembly has an eccentric bushing with a shank portion extending circumferentially about a first axis and defining a bore along a second axis. The second axis is generally parallel and offset from the first axis. The bushing has a head portion extending from the eccentric bushing portion, with the bore extending though the head portion. The bushing is sized for insertion into an aperture of a drill feed guide wear pad, and is rotatable causing the shank portion to engage the aperture of the wear pad to provide a camming action to position the wear pad relative to a drill feed guide. The head portion is shaped to interact with a tool for rotating the bushing.

    Abstract translation: 提供凸轮组件用于调整钻进给导轨磨耗垫。 凸轮组件具有偏心衬套,其具有沿着第一轴线周向延伸并且沿着第二轴线限定孔的柄部分。 第二轴线通常平行并偏离第一轴线。 衬套具有从偏心衬套部分延伸的头部,孔径延伸穿过头部。 衬套的尺寸适于插入钻进给导向器磨损垫的孔中,并且可旋转,使得柄部接合耐磨垫的孔,以提供相对于钻进给导轨定位磨损垫的凸轮作用。 头部被成形为与用于旋转衬套的工具相互作用。

    METHODS OF DIFFERENTIATING AND PROTECTING CELLS BY MODULATING THE P38/MEF2 PATHWAY
    357.
    发明申请
    METHODS OF DIFFERENTIATING AND PROTECTING CELLS BY MODULATING THE P38/MEF2 PATHWAY 有权
    通过调节P38 / MEF2途径来分化和保护细胞的方法

    公开(公告)号:US20110212070A1

    公开(公告)日:2011-09-01

    申请号:US13077752

    申请日:2011-03-31

    Abstract: The present invention provides a method of differentiating progenitor cells to produce a population containing protected neuronal cells. A method of the invention includes the steps of contacting the progenitor cells with a differentiating agent; and introducing into the progenitor cells a nucleic acid molecule encoding a MEF2 polypeptide or an active fragment thereof, thereby differentiating the progenitor cells to produce a population containing protected neuronal cells. In one embodiment, the MEF2 polypeptide is human MEF2C or an active fragment thereof.

    Abstract translation: 本发明提供了一种区分祖细胞以产生含有受保护的神经元细胞的群体的方法。 本发明的方法包括使祖细胞与分化剂接触的步骤; 并且向祖细胞中引入编码MEF2多肽或其活性片段的核酸分子,由此分化祖细胞以产生含有受保护的神经元细胞的群体。 在一个实施方案中,MEF2多肽是人MEF2C或其活性片段。

    Electronic system location determination
    360.
    发明授权
    Electronic system location determination 有权
    电子系统位置确定

    公开(公告)号:US07942936B2

    公开(公告)日:2011-05-17

    申请号:US11527799

    申请日:2006-09-27

    Inventor: Stuart A Golden

    CPC classification number: H04W64/00 H04W8/24 H04W84/12

    Abstract: A lost or stolen computing device is recovered. A trusted server is requested to locate the computing device. The trusted server requests coarse location information from the computing device, and the computing device reports its coarse location. The trusted server then requests that the computing device transmit wireless local area networks signal so that it may be recovered.

    Abstract translation: 丢失或被盗的计算设备被恢复。 请求信任的服务器来定位计算设备。 可信服务器从计算设备请求粗略位置信息,并且计算设备报告其粗略位置。 然后,可信服务器请求计算设备发送无线局域网信号,使其可以被恢复。

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