AN IMPROVED LOW-POWER MASS INTERROGATION SYSTEM AND ASSAY FOR DETERMINING VITAMIN D LEVELS

    公开(公告)号:AU2023274139B2

    公开(公告)日:2024-10-10

    申请号:AU2023274139

    申请日:2023-11-29

    Applicant: LEIDOS INC

    Abstract: A low power mass spectrometer assembly includes at least an ionization component, an electrostatic analyzer, a lens assembly, a magnet assembly and at least one detector located in a same plane as the entrance to the magnet assembly for detecting the deflected sample ions and/or fragments of sample ions, including ions or ion fragments indicative of the Vitamin D metabolite within the sample.

    PD-1 and CTLA-4 dual inhibitor peptides

    公开(公告)号:AU2018273958B2

    公开(公告)日:2022-07-21

    申请号:AU2018273958

    申请日:2018-05-25

    Applicant: LEIDOS INC

    Abstract: This disclosure provides peptides which have a strong affinity for the checkpoint receptor "programmed death 1" (PD-1). These peptides block the interaction of PD-1 with its ligand PD-L1 as well as the interaction of CTLA4 with CD86 and can therefore be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer; treating infectious diseases; enhancing a response to vaccination; treating sepsis; and promoting hair re-pigmentation or lightening of pigmented skin lesions.

    An improved low-power mass interrogation system and assay for determining vitamin D levels

    公开(公告)号:AU2019263158A1

    公开(公告)日:2020-11-19

    申请号:AU2019263158

    申请日:2019-04-30

    Applicant: LEIDOS INC

    Abstract: A low power mass spectrometer assembly includes at least an ionization component, an electrostatic analyzer, a lens assembly, a magnet assembly and at least one detector located in a same plane as the entrance to the magnet assembly for detecting the deflected sample ions and/or fragments of sample ions, including ions or ion fragments indicative of the Vitamin D metabolite within the sample.

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