피부 미백 물질 스크리닝 시스템
    35.
    发明公开
    피부 미백 물질 스크리닝 시스템 审中-实审
    候选材料筛选系统

    公开(公告)号:KR1020130043069A

    公开(公告)日:2013-04-29

    申请号:KR1020120114965

    申请日:2012-10-16

    Abstract: PURPOSE: A whitening material screening system is provided to effectively and simply screen a whitening material and to improve a skin whitening effect. CONSTITUTION: A whitening material screening system comprises one or more layers containing one or more cells among fibroblasts, keratinocytes, and melanocytes. The screening system comprises: a fibroblast layer containing fibroblasts; and a layer containing one or more of keratinocytes and melanocytes. The fibroblast layer contains fibroblasts in collagen. The screening system contains 0.001-30 wt% of the collagen.

    Abstract translation: 目的:提供美白材料筛选系统,以有效和简单地筛选美白材料并改善皮肤美白效果。 构成:美白材料筛选系统包括在成纤维细胞,角质形成细胞和黑素细胞中含有一个或多个细胞的一层或多层。 筛选系统包括:含有成纤维细胞的成纤维细胞层; 以及包含角质形成细胞和黑素细胞中的一种或多种的层。 成纤维细胞层含有胶原中的成纤维细胞。 筛选系统含有0.001-30重量%的胶原蛋白。

    피부 탄력 개선용 화장료 조성물
    36.
    发明公开
    피부 탄력 개선용 화장료 조성물 有权
    用于改善皮肤弹性的化妆品组合物

    公开(公告)号:KR1020120020716A

    公开(公告)日:2012-03-08

    申请号:KR1020100084506

    申请日:2010-08-31

    Abstract: PURPOSE: A cosmetic composition containing Phyllanthus urinaria extract and stabilized polymersomes is provided to enhance anti-wrinkling, skin elasticity, and skin moisturizing. CONSTITUTION: A cosmetic composition for improving skin elasticity contains a stabilized polymersomes as an active ingredient, containing Phyllanthus urinaria extract and anti-aging peptides. The anti-aging peptides are palmitoyl tripeptide-5 or diaminopropionoyl triepeptide-33. The stabilized polymersom is ABcell.

    Abstract translation: 目的:提供含有叶黄芩提取物和稳定的聚合物囊泡的化妆品组合物,以增强抗皱,皮肤弹性和皮肤保湿作用。 构成:用于改善皮肤弹性的化妆品组合物含有稳定的聚合物囊泡作为活性成分,含有叶黄芩提取物和抗衰老肽。 抗衰老肽是棕榈酰三肽-5或二氨基丙酰基三肽-33。 稳定的聚合物是ABcell。

    데옥시만노지리마이신을 함유하는 피부 미백용 조성물
    39.
    发明授权
    데옥시만노지리마이신을 함유하는 피부 미백용 조성물 有权
    데옥시만노지리마이신을함유유하는피부미백용조성물

    公开(公告)号:KR100680585B1

    公开(公告)日:2007-02-08

    申请号:KR1020060015148

    申请日:2006-02-16

    Abstract: A skin whitening composition with excellent whitening effect is provided to be able to effectively inhibit melanogenesis without side effects by comprising deoxymannojirimycin, which is mannosidase inhibitor, only or the deoxymannojirimycin and deoxynojirimycin in combination. The composition for skin whitening comprises deoxymannojirimycin as an effective ingredient. The composition further comprises deoxynojirimycin as an effective ingredient. Regarding the total weight of the composition, 0.001-20 wt.% of the effective ingredient is contained.

    Abstract translation: 本发明提供一种美白效果优异的皮肤美白用组合物,其仅通过组合包含作为甘露糖苷酶抑制剂的脱氧芒硝ji霉素或脱氧芒硝ri霉素和脱氧野ji霉素,而能够有效抑制无副作用的黑素生成。 用于皮肤增白的组合物包含脱氧芒硝ri霉素作为有效成分。 该组合物进一步包含脱氧野ri霉素作为有效成分。 关于组合物的总重量,含有0.001-20重量%的有效成分。

    멜라닌 생성 억제 펩티드, 그 제조방법, 및 이를함유하는 피부 외용제 조성물
    40.
    发明公开
    멜라닌 생성 억제 펩티드, 그 제조방법, 및 이를함유하는 피부 외용제 조성물 有权
    造血抑制肽,其制备方法和含有该成分的局部皮肤白化组合物

    公开(公告)号:KR1020030077271A

    公开(公告)日:2003-10-01

    申请号:KR1020020016298

    申请日:2002-03-26

    CPC classification number: C07K5/1016 A61K8/64 A61K38/07 A61Q19/00 A61Q19/02

    Abstract: PURPOSE: Provided is a melanogenesis-suppressing peptide which effectively suppresses the activation of tyrosinase in the melanogenesis cells. A topical skin-whitening composition containing the melanogenesis-suppressing peptide involves excellent skin whitening effect, and effective improvement and prevention of chloasma, freckles, and other melanin pigmentation. CONSTITUTION: The melanogenesis-suppressing peptide is selected from the group consisting of peptides with the amino acid sequences of SEQ ID NO 1-4. A method of manufacturing the melanogenesis-suppressing peptide comprises the steps of preparing chemical peptide random-sequenced mixtures with 76 cases of 4(locations)x19(amino acids); selecting two or three amino acids per the respective peptide locations with enzyme activity inhibitory effect from the peptide mixtures using tyrosinase extracted from mushrooms; synthesizing secondary peptides based on the selected peptide sequences; and testing the whitening effect and the cell stability of the secondary peptides, and finally selecting the peptide with the amino acid sequences of SEQ ID NO 1-4.

    Abstract translation: 目的:提供有效抑制黑素生成细胞中酪氨酸酶活化的黑素生成抑制肽。 含有黑素生成抑制肽的局部皮肤美白组合物具有优异的皮肤美白效果,有效改善和防止黄褐斑,雀斑和其他黑色素色素沉着。 构成:黑素生成抑制肽选自具有SEQ ID NO 1-4的氨基酸序列的肽。 制备黑素生成抑制肽的方法包括以下步骤:制备具有76个4(位置)x19(氨基酸)的76个化学肽随机排序的混合物; 使用从蘑菇提取的酪氨酸酶从肽混合物中选择两个或三个氨基酸,每个肽位置具有酶活性抑制作用; 基于所选择的肽序列合成二级肽; 并测试第二肽的美白效果和细胞稳定性,最后选择具有SEQ ID NO 1-4的氨基酸序列的肽。

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