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31.发明公开수수 및 수수 부산물 유래 폴리페놀계 화합물을 함유하는 추출물과 이를 유효성분으로 함유하는 염증성 질환 예방 및 치료용 약학 조성물 有权来自含有多环芳烃化合物的酸和副产物的提取物和用于治疗和预防包含其的炎症疾病的药物组合物
公开(公告)号：KR1020140065535A
公开(公告)日：2014-05-30
申请号：KR1020120129613
申请日：2012-11-15
Applicant: 대한민국(농촌진흥청장) , 충북대학교 산학협력단
IPC: A61K36/899 , A61K31/352 , A61K31/35 , A61P29/00
CPC classification number: A61K31/352 , A61K36/899 , Y10S514/857 , Y10S514/886 , Y10S514/894 , Y10S514/914
Abstract: The present invention relates to an extract containing a polyphenol-based compound derived from sorghum and sorghum by-products and a pharmaceutical composition for prevention and treatment of inflammatory diseases containing the same as an active ingredient. More specifically, the present invention relates to: an extract containing a polyphenol-based compound derived from sorghum and sorghum by-products, which has a useful effect on prevention and treatment of inflammatory disease by separating a polyphenol-based compound showing an anti-inflammatory effect from a sorghum extract, and which can be used for the ingredients of food and medicines as well as a natural anti-inflammatory drug, etc.; and a pharmaceutical composition for prevention and treatment of inflammatory diseases containing the same as an active ingredient.
Abstract translation: 本发明涉及含有由高粱和高粱副产物衍生的多酚类化合物的提取物和用于预防和治疗含有其作为活性成分的炎性疾病的药物组合物。 更具体地说，本发明涉及：含有源自高粱和高粱副产物的多酚类化合物的提取物，其通过分离显示抗炎药物的多酚类化合物对预防和治疗炎性疾病有有效的作用 高粱提取物的作用，可用于食品和药物的成分以及天然抗炎药物等; 以及用于预防和治疗含有其作为活性成分的炎性疾病的药物组合物。
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32.发明授权새싹보리 추출물을 포함하는 뉴라미니데이즈 활성 억제용 조성물 및 인플루엔자 바이러스 감염 질환의 예방 및 치료용 약학적 조성물 有权用于抑制神经氨酸酶活性的组合物和用于预防和治疗流感病毒疾病的药物组合物，其包括年轻大麦叶的提取物
公开(公告)号：KR101376231B1
公开(公告)日：2014-03-26
申请号：KR1020110020660
申请日：2011-03-08
Applicant: 대한민국(농촌진흥청장)
IPC: A61K36/8998 , A61K31/37 , A61P31/16 , A61P31/00
Abstract: 본 발명은 뉴라미니데이즈 억제활성을 가지는 새싹보리 추출물 및 폴리페놀계 화합물에 관한 것으로서, 보다 상세하게는 새싹보리 유래 폴리페놀계 화합물을 추출하여 분리하고, 이의 뉴라미니데이즈 억제 활성을 확인하여 인플루엔자 바이러스의 예방, 치료 등에 적용할 수 있는 조성물에 관한 것이다.
본 발명은 인플루엔자 바이러스 표면 항원인 동시에 새로 생성된 바이러스를 세포밖으로 방출하는데 중요한 역할을 담당하는 효소인 뉴라미니데이즈에 대하여 새싹보리의 폴리페놀계 화합물들이 강한 억제효과가 있음을 확인함으로써 생물의약, 건강기능 식품산업과 식·의약분야 및 가축 사료 첨가제 분야에서 새싹보리의 활용성을 증진시킬 수 있을 것으로 기대된다.-
33.发明公开흑미 추출물을 유효성분으로 함유하는 헬리코박터 파이로리 유래 질환의 예방 또는 치료용 약학적 조성물 및 건강식품 无效用于预防或治疗由包括提取黑麦和健康食品的HELICOBACTER PYLORI衍生的疾病的组合物
公开(公告)号：KR1020140017818A
公开(公告)日：2014-02-12
申请号：KR1020120084430
申请日：2012-08-01
Applicant: 대한민국(농촌진흥청장) , 연세대학교 원주산학협력단
IPC: A61K36/899 , A61P1/04 , A61P1/00
Abstract: The present invention relates to a pharmaceutical composition for preventing or treating Helicobacter pylori infectious diseases which includes extract of black rice or black rice solvent fractions as an active ingredient and a method for manufacturing black rice solvent fractions. More specifically, the active ingredients of the black rice extract or black rice derived cyanidin-3-O-glucoside black rice fractions show activities of growth inhibition of the Helicobacter pylori, inhibition of Helicobacter pylori urease, and toxin secretion inhibition of CagA, VacA, SecA, and are safe and natural black rice derived materials so that active ingredients of the black rice extract or black rice derived cyanidin-3-O-glucoside black rice fractions can be used as the pharmaceutical composition, health supplement, drink and additives for preventing or treating the Helicobacter pylori which are safe, have low toxicity, and inhibits the generation of resistant bacteria caused by abusing antibiotics.
Abstract translation: 本发明涉及一种用于预防或治疗幽门螺杆菌感染性疾病的药物组合物，其包括黑米或黑米溶剂级分的提取物作为活性成分，以及黑米溶剂级分的制造方法。 更具体地说，黑米提取物或黑米衍生的花青素-3-O-葡萄糖苷黑米级部分的活性成分显示了幽门螺旋杆菌的生长抑制活性，幽门螺杆菌脲酶的抑制以及CagA，VacA的毒素分泌抑制， SecA，并且是安全和天然的黑米衍生材料，使得黑米提取物或黑米衍生的花青素-3-O-葡萄糖苷黑米级分的活性成分可用作药物组合物，健康补充剂，饮料和预防添加剂 或治疗安全的幽门螺杆菌，具有低毒性，并且抑制由滥用抗生素引起的抗性细菌的产生。
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公开(公告)号：KR101296208B1
公开(公告)日：2013-08-13
申请号：KR1020120081932
申请日：2012-07-26
Applicant: 대한민국(농촌진흥청장) , 경북대학교 산학협력단
CPC classification number: D01F1/103 , A61L15/10 , A61L26/0014 , D01D1/02 , D01D5/0015 , D01F6/14
Abstract: PURPOSE: A polyvinyl alcohol nanofiber which contains sorghum pigment is provided to show high antibiotic material and be used as wound coating flux which is medical material due to no cytotoxicity. CONSTITUTION: The sorghum by-product extract is the golden chalsusu stem extract and the golden chalsusu stem extract. The component of the sorghum extract or the sorghum by-product extract is chemical formula 1 or chemical formula 2.
Abstract translation: 目的：提供含有高粱颜料的聚乙烯醇纳米纤维，以显示高抗生素材料，并且由于没有细胞毒性而用作医疗材料的伤口涂层助焊剂。 构成：高粱副产品提取物是金黄色素提取物和金黄色素提取物。 高粱提取物或高粱副产物提取物的组分是化学式1或化学式2。
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公开(公告)号：KR101293689B1
公开(公告)日：2013-08-08
申请号：KR1020110062328
申请日：2011-06-27
Applicant: 대한민국(농촌진흥청장)
Abstract: 본 발명은 오크라 종자를 함유하는 기능성 차의 제조방법에 관한 것으로서, 오크라 종자를 150-230 ℃에서 8-15 분간 볶는 단계, 상기 볶은 오크라 종자를 열풍건조하거나 동결건조한 후에, 분쇄기로 분쇄하는 단계 및 상기 분쇄가루를 과립포장하거나 티백으로 포장하는 단계를 포함하는 것을 특징으로 하며, 본 발명에 따른 오크라 종자 추출물을 포함하는 조성물은 유리 아미노산 및 폴리페놀성 화합물을 함유하고 있어서 우수한 항산화 활성을 가지고, 이를 포함하는 오크라 종자 함유 기능성 차 역시 항산화 활성을 가진다. 이에 따라 본 발명에 따른 오크라 종자 함유 기능성 차는 노화 방지 등의 건강 보조 기능성 식품이 될 수 있으며, 특히 오크라 차의 맛이 커피와 유사하여 커피 대체용 차로도 개발할 수 있다.
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Patent Agency Ranking
公开(公告)号：KR1020120019063A
公开(公告)日：2012-03-06
申请号：KR1020100082174
申请日：2010-08-24
Applicant: 대한민국(농촌진흥청장) , 주식회사 에버그린
Abstract: PURPOSE: A biodegradable plant propagation multi-pot is provided to have moderate strength for plant propagation, and to improve sterilization ability, deodorant ability and heterogeneity, and to be naturally degradable in soil. CONSTITUTION: An environment-friendly composition for plant propagation comprises 30-60 weight% of rice chaff, 5-15 weight% of rice bran, 5-15 weight% of starch, 5-10 weight% of urea, 1-10 weight% of titanium powder, and 20-30 weight% of water. A manufacturing method thereof comprises: a step of crushing the rice chaff and the rice bran by using a pulverizer; a step of forming a composition for plant propagation by using the crushed rice chaff and the rice bran; a step of mixing the composition for plant propagation for 10-20 minutes; and a step of molding the composition by heating and pressurizing.
Abstract translation: 目的：提供生物降解植物繁殖多盆，具有植物繁殖中等强度，提高灭菌能力，除臭能力和异质性，并在土壤中自然降解。 构成：用于植物繁殖的环境友好组合物包括30-60重量％的稻糠，5-15重量％的米糠，5-15重量％的淀粉，5-10重量％的尿素，1-10重量％ 的钛粉末和20-30重量％的水。 其制造方法包括：使用粉碎机粉碎稻糠和米糠的步骤; 通过使用粉碎的米糠和米糠形成用于植物繁殖的组合物的步骤; 将植物繁殖用组合物混合10-20分钟的步骤; 以及通过加热加压成型该组合物的步骤。
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公开(公告)号：KR1020110088304A
公开(公告)日：2011-08-03
申请号：KR1020100008156
申请日：2010-01-28
Applicant: 대한민국(농촌진흥청장)
IPC: G01N33/10 , G01N33/02 , G01N31/00 , G01N21/359
Abstract: PURPOSE: A non-destructive analysis method is provided to effectively analyze ingredient consisting of fatty acid of a grain. CONSTITUTION: A non-destructive analysis method for a fatty acid composition of a single granule comprises: a step of randomly selecting a plurality of prediction model development group and prediction model evaluation group; a step of measuring near infrared absorption spectrum of two groups; a step of randomly selecting grain granule sample among the prediction model development groups and measuring near infrared ray absorption spectrum; a step of pulverizing the granule sample and performing chemical analysis of fatty acid ingredients; and a step of applying primary and secondary derivatives to the absorption spectrum.
Abstract translation: 目的：提供一种非破坏性分析方法，有效分析由谷物脂肪酸组成的成分。 构成：单粒子脂肪酸组成的无损分析方法包括：随机选择多个预测模型开发组和预测模型评价组的步骤; 测量两组近红外吸收光谱的步骤; 在预测模型开发组中随机选择颗粒样品并测量近红外线吸收光谱的步骤; 粉碎颗粒样品并进行脂肪酸成分的化学分析的步骤; 以及将一次和二次衍生物应用于吸收光谱的步骤。
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公开(公告)号：KR1020110085758A
公开(公告)日：2011-07-27
申请号：KR1020100005714
申请日：2010-01-21
Applicant: 대한민국(농촌진흥청장)
IPC: A61K36/899 , A61K31/37 , A61K31/7048 , A61P17/00
CPC classification number: A61K31/192 , A23L29/035 , A61K8/368 , A61K8/498 , A61K8/602 , A61K8/97 , A61K31/352 , A61K31/7048 , A61K36/8998 , A61K2236/33
Abstract: PURPOSE: A method for preparing extract derived from young barley leaf is provided to isolate novel ingredients and to be used as a functional material supply source. CONSTITUTION: A young barley leaf extract with an antioxidative activity is prepared using an organic solvent. The young barley leaf is collected in a length of 10-20 cm and is freeze-dried. The organic solvent is methanol or ethanol. The ethanol is 80-90 weight% ethanol solution. A composition for skin whitening or anti-aging contains the extract as an active ingredient. A health food for skin whitening or anti-aging contains the extract as an active ingredient. A solvent fraction of the extract contains one or more compounds selected from compound of chemical formulas 1-4.
Abstract translation: 目的：提供一种制备从年轻大麦叶提取的提取物的方法，用于分离新成分并用作功能材料供应源。 构成：使用有机溶剂制备具有抗氧化活性的年轻大麦叶提取物。 收集年轻的大麦叶，长度为10-20厘米，冷冻干燥。 有机溶剂为甲醇或乙醇。 乙醇为80-90重量％乙醇溶液。 用于皮肤美白或抗衰老的组合物含有提取物作为活性成分。 用于皮肤美白或抗衰老的保健食品含有提取物作为活性成分。 提取物的溶剂馏分含有一种或多种选自化学式1-4化合物的化合物。
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公开(公告)号：KR100552617B1
公开(公告)日：2006-02-15
申请号：KR1020030061429
申请日：2003-09-03
Applicant: 대한민국(농촌진흥청장)
IPC: C07C47/225
Abstract: 양하에서 분리정제한 라브다-12-엔-15,16-디알 화합물 및 이의 분리 정제방법에 관한 것으로서,
양하의 화뢰와 근경을 음건하여 메탄올로 추출한 후 농축시켜 에틸아세테이트층, 부탄올층, 물층으로 분획화 하였으며, 에틸아세테이트층을 실리카겔 칼럼 크로마토그래피를 실시하여 라브다-12-엔-15,16-디알(labda-12-ene-15,16-dial) 화합물을 분리하였으며, NMR, IR등의 분광학적 방법을 이용하여 구조동정한 결과 하기 화학식 1의 신규의 화합물이다.
(화학식 1)
라브다-12-엔-15,16-디알 화합물은 항균활성 및 항암활성을 가진다.
양하, 라브다-12-엔-15,16-디알, 의약품, 치료보조식품
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