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31.发明公开후각 수용체 단백질을 코딩하는 유전자로 형질 전환된 동물세포로부터 후각 수용체 단백질을 포함하는 나노 베지클을 제조하는 방법, 이에 의하여 제조된 후각 수용체 단백질을 포함하는 나노 베지클, 상기 나노 베지클이 표면에 고정화된 단일벽 탄소나노튜브 전계 효과 트랜지스터 및 이를 이용하는 생체전자코 无效纳米囊泡的制造方法，包括嗅觉受体蛋白从与嗅觉受体蛋白编码基因，纳米囊泡，COMPRISING同样的制造，单壁碳纳米管晶体管嗅觉受体蛋白转染的哺乳动物细胞上固定面同样的制造纳米囊泡，和生物电子 使用由其制造的纳米晶体的方法
公开(公告)号：KR1020120083987A
公开(公告)日：2012-07-27
申请号：KR1020110005256
申请日：2011-01-19
Applicant: 서울대학교산학협력단
IPC: C12N15/12 , C07K14/47 , G01N27/327 , A61F2/72
Abstract: PURPOSE: A method for preparing nano vesicles containing olfactory receptor proteins is provided to ensure high selectivity and sensitivity. CONSTITUTION: A method for preparing nano vesicles containing olfactory receptor protein comprises: a step of transforming animal cells with a gene encoding the protein; a step of treating the animal cells with a compound to secrete nano vesicles containing the proteins; and a step of centrifuging the isolated nano vesicles. A transistor in which the nano vesicle is fixed comprises: a source electrode and a drain electrode separately formed on a substrate; a nanostructure which electrically contacts with the electrodes and is formed between the electrodes; and the protein on the surface of the electrodes and nanostructure.
Abstract translation: 目的：提供一种制备含有嗅觉受体蛋白的纳米囊泡的方法，以确保高选择性和灵敏度。 构成：制备含有嗅觉受体蛋白质的纳米囊泡的方法，包括：用编码蛋白质的基因转化动物细胞的步骤; 用化合物处理动物细胞以分泌含有蛋白质的纳米囊泡的步骤; 以及离心分离的纳米囊泡的步骤。 纳米小泡固定的晶体管包括：分别形成在基板上的源电极和漏电极; 与电极电接触并形成在电极之间的纳米结构; 和电极表面的蛋白质和纳米结构。
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32.发明公开후각 반응을 증가시키는 세포 기반 후각 센서 및 이를 이용한 후각 반응을 증가시키는 방법 有权用于增加OLFACTORY反应的OLFACTORY传感器和使用该方法增加OLFACTORY反应的方法
公开(公告)号：KR1020110008571A
公开(公告)日：2011-01-27
申请号：KR1020090065980
申请日：2009-07-20
Applicant: 서울대학교산학협력단
IPC: G01N27/327 , G01N33/497 , G01N27/416
Abstract: PURPOSE: A cell-based olfactory sensor for increasing olfactory reaction and a method for increasing olfactory reaction using the same are provided to improve sensitivity on low olfactory reaction by increment in the olfactory reaction of olfactory cells. CONSTITUTION: A cell-based olfactory sensor for increasing olfactory reaction comprises an MEA(10), a wire portion(20), a chamber(30), an olfactory receptor protein expressed recombinant cell(40), a stimulation signal supplying unit(50), an output signal processing unit(60), a buffer(70), and a reference electrode(80). The wire portion is connected to the MEA. The chamber is formed in order to hold culture fluid for the cell culture on the substrate of the MEA. The cell is cultivated in the MEA within the chamber. The stimulation signal supplying unit applies sensitive signals to the cell cultivated in the MEA. The output signal processing unit outputs the variations of voltage at the cell cultivated in the MEA. The buffer is included within the chamber. The electrode is dipped in the buffer.
Abstract translation: 目的：提供一种用于增加嗅觉反应的基于细胞的嗅觉传感器，以及使用其提高嗅觉反应的方法，以通过嗅觉细胞的嗅觉反应增加来提高对低嗅觉反应的敏感性。 构成：用于增加嗅觉反应的基于细胞的嗅觉传感器包括MEA（10），线部分（20），室（30），表达重组细胞的嗅觉受体蛋白（40），刺激信号提供单元（50） ），输出信号处理单元（60），缓冲器（70）和参考电极（80）。 电线部分连接到MEA。 形成腔室以便将细胞培养物的培养液保持在MEA的基质上。 细胞在室内的MEA中培养。 刺激信号提供单元对MEA中培养的细胞施加敏感信号。 输出信号处理单元输出在MEA中培养的细胞上的电压变化。 缓冲器包含在腔室内。 将电极浸入缓冲液中。
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公开(公告)号：KR101757267B1
公开(公告)日：2017-07-13
申请号：KR1020150094708
申请日：2015-07-02
Applicant: 서울대학교산학협력단 , 알에스오토메이션주식회사
IPC: H02P29/00
Abstract: 본발명의일 실시예는전류명령을발생시키는서보제어기에서발생된전류명령으로부터공진및 공진억제를감지하는공진감지기, 상기전류명령의주파수를추정하는주파수추정기및 상기주파수추정기에의해추정된주파수를노치주파수로하여상기전류명령을필터링하는적응노치필터를포함하는적응노치필터를이용한서보시스템의자동공진억제장치를개시한다. 또한다른일 실시예는서보제어기에서발생된전류명령으로부터공진을감지하는단계, 상기전류명령의주파수를추정하는단계및 상기주파수추정기에의해추정된주파수를적응노치필터의노치주파수로하여상기전류명령을필터링하는단계를포함하는적응노치필터를이용한서보시스템의자동공진억제방법을개시한다.
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公开(公告)号：KR101643336B1
公开(公告)日：2016-07-27
申请号：KR1020140138495
申请日：2014-10-14
Applicant: 서울대학교산학협력단
Inventor： 이상훈
IPC: C04B35/447 , C04B35/64
Abstract: 본발명은알칼리족금속이온과할로겐족이온이수산화인회석의칼슘과수산화이온자리에동시에부분치환되며, 탄산이온자리와수산화이온의수소이온자리에각각양과음으로공공(vacancy)이부분적으로형성되고, 일부수산화이온중 수소이온의소실에의해형성된비가교산소와수산화이온일부자리에치환된할로겐족이온이주위수산화이온과수소결합을형성, 수산화이온이대칭배열된구조(tail-to-tail structure)를갖는수산화인회석(hydroxyapatite)과이런수산화인회석과삼인산칼슘(tricalcium phosphate)이균일하게혼합된이상인회석(biphasic calcium phosphate) 및이의제조방법에관한것이다. 본발명에따르면, 다중이온동시치환에의해수산화인회석구조의불안정성이높아져수산화인회석의용해도가증가하며, 이는이러한수산화인회석을포함하는인회석세라믹스의생체활성및 골전도도를향상시키는결과를가져올수 있다.
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公开(公告)号：KR101601255B1
公开(公告)日：2016-03-08
申请号：KR1020150040834
申请日：2015-03-24
Applicant: 서울대학교산학협력단
Abstract: 본발명은혈소판농축혈장(platelet rich plasma; PRP) 분리장치에관한것이다. 본발명의장치는크게 (ⅰ) (ⅰ-1) 상부몸체; (ⅰ-2) 중간몸체; 및 (ⅰ-3) 하부몸체를포함하는몸체(body); 및 (ⅱ) (ⅱ-1) 백혈구필터상체; 및 (ⅱ-2) 백혈구필터하체를포함하는백혈구필터(filter)를포함하여, 혈소판의농도는높고백혈구의수는낮은, 즉혈소판/백혈구의비가높은혈소판농축혈장(platelet rich plasma; PRP)을분리할수 있다. 또한, 종래의키트(kit)와는달리 PRP를분리해내는과정에서백혈구가필터를통해제거되므로, 손상조직에투여시 백혈구및 이로부터분비되는각종이화작용사이토카인으로인한부정적인효과가감소되고, 최종적으로는 PRP를통한조직치유효과를극대화할수 있을것으로기대된다.
Abstract translation: 本发明涉及富含血小板的血浆（PRP）分离装置。 根据本发明，所述装置包括：（i）主体，包括（i-1）上身，（i-2）中身，和（i-3）下身; 和（ii）包含（ii-1）上白细胞过滤体和（ii-2）下白细胞过滤体的白细胞过滤器。 该装置可以分离具有高血小板/白细胞比率的PRP，其意味着高血小板浓度率和低数量的白细胞。 因此，当与受损组织一起使用时，该装置使用PRP分离过程中的过滤器除去白细胞，与常规试剂盒不同，以减少白细胞引起的不良反应和来自白血的分解代谢细胞因子 同时通过PRP最大化组织愈合。
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Patent Agency Ranking
公开(公告)号：KR1020140126851A
公开(公告)日：2014-11-03
申请号：KR1020130044763
申请日：2013-04-23
Applicant: 서울대학교산학협력단 , 알에스오토메이션주식회사
CPC classification number: G05B13/0245 , G05B13/045 , G05B19/18 , H02P23/0004 , H02P29/027
Abstract: A method for controlling a servo motor using a variable structure controller includes the steps of: setting a simplified model in the discrete time of a current limiting controller and the servo motor; defining a switching function for the model; producing an estimated value for disturbance by a relation with the switching function; and producing a control input which includes the estimated value for disturbance and makes the switching function 0.
Abstract translation: 使用可变结构控制器控制伺服电动机的方法包括以下步骤：在限流控制器和伺服电动机的离散时间内设置简化模型; 定义模型的切换功能; 通过与切换功能的关系产生干扰的估计值; 并产生包括干扰估计值并使切换功能为0的控制输入。
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公开(公告)号：KR1020130129079A
公开(公告)日：2013-11-27
申请号：KR1020130029118
申请日：2013-03-19
Applicant: 서울대학교산학협력단 , 알에스오토메이션주식회사
IPC: G01D5/36
CPC classification number: G01D5/3473 , G01D5/24471 , G01D5/34792 , G01D5/36 , G01D18/00
Abstract: The present invention relates to a method for sensing absolute rotation angles in an optical rotary encoder, and more specifically to an optical encoder provided with a signal track to generate signal pulses capable of calibrating errors upon generating upper bits in a Vernier type. The optical encoder according to an embodiment example of the present invention is an optical-type rotary encoder of Vernier type generating information on absolute position rotation angles, including; a master track generating the sine-wave signals of a fastest period; and a Vernier track generating the sine-wave signals of a period reduced from the master track period by a given value; and a digital track generating digital pulse signals with a period proportional to the sine-wave signal period of the master track.
Abstract translation: 本发明涉及一种用于在光学旋转编码器中检测绝对旋转角度的方法，更具体地说，涉及一种具有信号轨迹的光学编码器，该光学编码器产生能够在以游标类型生成高位时校正误差的信号脉冲。 根据本发明实施例的光学编码器是关于绝对位置旋转角的游标类型的光学式旋转编码器，包括： 主轨道产生最快周期的正弦波信号; 以及游标轨道，其产生从主轨道周期减少给定值的周期的正弦波信号; 以及产生具有与主轨道的正弦波信号周期成比例的周期的数字脉冲信号的数字轨迹。
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公开(公告)号：KR1020130005915A
公开(公告)日：2013-01-16
申请号：KR1020110067606
申请日：2011-07-08
Applicant: 서울대학교산학협력단
IPC: A61N1/36 , A61B5/0476 , A61B5/0482 , A61N1/08
CPC classification number: A61N1/36 , A61B5/0476 , A61B5/0482 , A61N1/08
Abstract: PURPOSE: A spasm end-point decision method using sample entropy of brain wave is provided to rapidly measure the end-point of spasm. CONSTITUTION: A spasm end-point decision method using sample entropy of brain wave comprises the following steps: obtaining brain wave change data according to time from experimentee; using starting time point information of the section after partitioning the brainwave data according to the time of 1-20 seconds; measuring the sample entropy value about the divided each section; selecting N number of sections by selecting the section having the lowest sample entropy value in order; reversely, calculating the absolute mean value of the brain wave amplitude up to 5-20 seconds before; distinguishing the status convulsivus and ratio status convulsivus; and determining the starting point of the last section as the spasm end-point.
Abstract translation: 目的：提供使用脑波样本熵的痉挛终点决策方法，快速测量痉挛的终点。 构成：使用脑波样本熵的痉挛终点决策方法包括以下步骤：根据实验者的时间获取脑波变化数据; 根据1-20秒的时间划分脑波数据后，使用该部分的开始时间点信息; 测量关于分割的每个部分的样本熵值; 通过选择具有最低样本熵值的部分来选择N个部分; 相反，计算脑波幅度的绝对平均值高达5-20秒; 区分痉挛状态和比例状态惊厥; 并将最后一节的起点确定为痉挛终点。
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公开(公告)号：KR1020120121032A
公开(公告)日：2012-11-05
申请号：KR1020110038755
申请日：2011-04-26
Applicant: 알에스오토메이션주식회사 , 서울대학교산학협력단
CPC classification number: G01D5/3473 , G01D5/34707 , G01D5/36
Abstract: PURPOSE: An optical encoder having a code disc of a two dimension form and light signal receiving unit is provided to manufacture a small code disc depending on the reduction of track numbers and arrange disc patterns arranged as one dimension as two dimension form, thereby reducing the influence of aligning errors generated when assembling a code disc and light signal receiving unit for manufacturing an optical encoder. CONSTITUTION: An optical encoder comprises code patterns and an light signal receiving unit(101). The code pattern is arranged in a two dimensional form with respect to the code disc patterns for generating rotational angle information. The light receiving unit comprises a light receiving element array being arranged in the two dimensional form for sensing the code pattern. [Reference numerals] (AA) Light emitting unit; (BB) Motor rotary shaft; (CC) Code disc; (DD) Light receiving unit; (EE) Disc patterns for sensing a position
Abstract translation: 目的：提供一种具有二维码盘和光信号接收单元的光学编码器，以根据轨道号的减少制造小码盘，并将布置为一维的盘图案布置为二维形式，从而减少 在组装代码盘时产生的对准误差和用于制造光学编码器的光信号接收单元的影响。 构成：光学编码器包括码模式和光信号接收单元（101）。 代码图案相对于用于产生旋转角度信息的代码盘图案以二维形式布置。 光接收单元包括以二维形式布置的用于感测代码图案的光接收元件阵列。 （附图标记）（AA）发光单元; （BB）电机旋转轴; （CC）代码光盘; （DD）光接收单元; （EE）用于感测位置的光盘模式
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40.发明公开
公开(公告)号：KR1020110108661A
公开(公告)日：2011-10-06
申请号：KR1020100027992
申请日：2010-03-29
Applicant: 서울대학교산학협력단
IPC: G01N27/414 , G01N33/02 , B82B3/00
CPC classification number: G01N27/414 , B82B3/0095 , G01N27/4146 , G01N33/02
Abstract: 본 발명은 인간 미각 수용체 기능화된 단일벽 탄소 나노튜브-전계효과 트랜지스터(swCNT-FET)에 기초하고 인간의 미각 시스템을 모사한 고선택성의 바이오 전자혀에 관한 것이다. 본 발명자들은 최초로 미각 수용체 단백질을 인공혀에 적용하였으며 고선택성, 고민감성의 전자혀를 성공적으로 증명하였다. 이는 인간의 미각 수용체 단백질을 전자혀의 1차 신호 변환기로 사용함으로써 인간의 미각 시스템을 모방하는 전자혀를 구현하였다. 또한 기존의 전자혀에 비해 선택성과 민감성 측면에서 매우 우수하다. 본 발명에 의한 바이오 전자혀는 식품 산업에서 품질검사의 목적이나 맛 물질의 선별을 위한 도구로 사용될 수 있다.
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