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31.发明授权
公开(公告)号：KR101778203B1
公开(公告)日：2017-09-26
申请号：KR1020160125103
申请日：2016-09-28
Applicant: 한국과학기술연구원 , 울산대학교 산학협력단
IPC: A61K36/28 , A23L33/105
CPC classification number: A61K36/28 , A23L33/105 , A23L33/30 , A23L33/40 , A23V2002/00 , A23V2200/30 , A23V2250/21
Abstract: 이고들빼기 (denticulatum) 식물체의추출물을유효성분으로포함하는개체에서허혈-재관류손상을예방또는치료하기위한약학적조성물, 식품용조성물및 상기약학적조성물을이용한허혈-재관류손상을예방또는치료하기위한방법을제공한다.
Abstract translation: 并在包含该植物作为活性成分的提取物中的对象中的减号（蟹）缺血 - 用于预防或治疗再灌注损伤，用于使用所述药物组合物来预防或治疗再灌注损伤的食物和局部缺血的组合物的药物组合物 。“
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33.发明授权피뿌리뿔 추출물 또는 그의 분획물을 포함하는 상처를 치료하기 위한 조성물 및 개체의 상처를 치료하는 방법 有权用于处理含有STELLERA CHAMAEJASME提取物或其分解物的组合物和用于处理受试者的方法
公开(公告)号：KR101597762B1
公开(公告)日：2016-02-25
申请号：KR1020150052084
申请日：2015-04-13
Applicant: 한국과학기술연구원
IPC: A61K36/83
CPC classification number: A61K36/83 , A61K2236/30 , A61K2236/35 , A61K2236/39
Abstract: 피뿌리풀추출물또는그의분획물을유효성분으로서포함하는상처를치료하기위한조성물및 개체의상처를치료하는방법을제공한다.
Abstract translation: 本发明提供一种治疗伤口的组合物，其特征在于，含有天竺葵提取物或其一部分，以及对象物的伤口治疗方法。 Stellera chamaejasme L.提取物是从Stellera chamaejasme L.的地上部分提取的组合物，并且通过乙醇提取物获得Stellera chamaejasme L.提取物。 伤口由切口，擦伤，热或撕裂，部分，挫伤，烧伤或截肢引起。
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公开(公告)号：KR101484948B1
公开(公告)日：2015-01-22
申请号：KR1020130094036
申请日：2013-08-08
Applicant: 한국과학기술연구원
CPC classification number: A61K36/185 , A23L33/105 , A23V2002/00 , A23V2200/304 , A61K8/97 , A61Q19/00
Abstract: 본 발명은 돌단풍 추출물을 포함하는 조성물에 관한 것이다.
Abstract translation: 本发明涉及一种组合物，其中包括Aceriphyllum rosii Engler（Rose mukdenia）提取物。 更具体地，在本发明中，提供了用于治疗或预防包括玫瑰木提取物作为活性成分的过敏的药物组合物。 本发明的玫瑰invention invention具有抗氧化活性和抗癌活性等各种药理作用。 包含提取物的组合物可以防止产生过敏的物质，从而从根本上防止与现有的过敏治疗材料相比过敏。
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公开(公告)号：KR1020140013205A
公开(公告)日：2014-02-05
申请号：KR1020120079425
申请日：2012-07-20
Applicant: 한국과학기술연구원
Inventor： 노주원 , 강경수 , 이희주 , 오이도브삼부사랑게렐
IPC: A61K31/7034 , A61K31/7028 , A61K31/35 , A61P1/16
CPC classification number: A61K31/7034 , A23L29/035 , A61K31/7048 , A61K36/65 , Y10S514/893
Abstract: The present invention relates to a composition for protecting liver, specifically a composition for protecting liver containing a specific compound. The composition of the present invention inhibits the liver cell death, and reduces the concentration of reactive oxygen species (ROS). The composition of the present invention recovers the contents of glutathione, and cures the liver damage by alcohol. [Reference numerals] (AA) Hepatocyte viability(%); (BB) Control group; (CC) Quercetin; (DD) Formula 3 compound; (EE) Induce oxidative stress; (FF) Formula 4 compound; (GG) Injection and concentration(關M)
Abstract translation: 本发明涉及一种用于保护肝脏的组合物，特别涉及用于保护含有特定化合物的肝的组合物。 本发明的组合物抑制肝细胞死亡，降低活性氧（ROS）的浓度。 本发明的组合物回收谷胱甘肽的含量，并用乙醇治愈肝脏损伤。 （AA）肝细胞存活率（％） （BB）对照组; （CC）槲皮素; （DD）式3化合物; （EE）诱导氧化应激; （FF）式4化合物; （GG）注射和浓缩（关M）
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Patent Agency Ranking36.发明授权이고들빼기 추출물을 유효성분으로 함유하는 체중감량 및 비만의 예방과 치료용 조성물 有权通过含有Crepidiastrum denticulatum的提取物来减轻体重，预防和治疗肥胖的组合物
公开(公告)号：KR101266998B1
公开(公告)日：2013-05-30
申请号：KR1020110102492
申请日：2011-10-07
Applicant: 한국과학기술연구원
Abstract: 본발명은이고들빼기() 추출물을유효성분으로함유하는체중감량및 비만의예방과치료용조성물에관한것으로, 본발명에따른이고들빼기추출물은고지방식이를섭취한마우스의체중증가저해효과와고지방식이에따른비알코올성지방간억제효과가있으므로, 본발명에따른조성물은체중감량및 비만의예방과치료를위한약제및 건강기능식품에유용하게사용될수 있다.
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公开(公告)号：KR1020100089549A
公开(公告)日：2010-08-12
申请号：KR1020090008855
申请日：2009-02-04
Applicant: 한국과학기술연구원
Inventor： 노주원 , 판철호 , 정상훈 , 김철영 , 엄병헌 , 이샛별 , 강경수 , 유지혜 , 차광현 , 구송이 , 송대근 , 이은하 , 이희주 , 윤지호 , 김명수 , 안수용 , 김종환 , 강석우
IPC: A23L1/30 , A61P35/00 , A61K36/282 , A23L2/38
CPC classification number: A61K36/28 , A23L33/105 , A23V2002/00 , A23V2200/308 , A23V2250/21 , A23V2300/14 , A23V2300/18
Abstract: PURPOSE: A composition containing extract and portions of southernwood wild plants as an active ingredient is provided to activate quinone reductase which is an indicator enzyme for preventing cancer and to activate an antioxidant response element by including extracts and portions of the southernwood wild plants including Adenocaulon himalaicum or Artemisia dubia. CONSTITUTION: A composition for preventing cancers contains extracts and portions of southernwood wild plants including Adenocaulon himalaicum and Artemisia dubia as an active ingredient. The extracts are obtained by extracting dried Adenocaulon himalaicum or Artemisia dubia using alcohol having a carbon number of 1-4 or a mixed solvent. The portions are n-hexane portions, ethylacetate portions, n-butanol portions, or water portions.
Abstract translation: 目的：提供一种含有提取物和南部野生植物部分作为活性成分的组合物，用于活化醌还原酶，该还原酶是预防癌症的指示酶，并通过包括南木野生植物的提取物和部分，包括喜马拉松（Adenocaulon himalaicum） 或艾蒿（Artemisia dubia）。 构成：用于预防癌症的组合物含有南木野生植物的提取物和部分，其中包括Adenocaulon himalaicum和Artemisia dubia作为活性成分。 通过使用碳数为1-4的醇或混合溶剂提取干燥的Adenocaulon himalaicum或艾蒿，得到提取物。 这些部分是正己烷部分，乙酸乙酯部分，正丁醇部分或水部分。
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公开(公告)号：KR100856486B1
公开(公告)日：2008-09-04
申请号：KR1020070032294
申请日：2007-04-02
Applicant: 한국과학기술연구원
IPC: A61K36/88
Abstract: A method for extraction of tectoridin and tectorigenin from the rhizomes of Belamcanda chinensis is provided to reduce the extraction time, improve the extraction yield and enhance environment and human affinity by using only water and ethanol as solvent under high temperature and high pressure. The tectoridin and tectorigenin are extracted from the rhizomes of Belamcanda chinensis through SWE(subcritical water extraction) by heating the rhizomes of Belamcanda chinensis in a mixed solvent containing water and 30-100 vol.% of ethanol to high temperature such as 80 deg. C or more, preferably 80-200 deg. C under high pressure condition such as 1-15 MPa.
Abstract translation: 提供了一种从中华白兰地根茎提取t idin素和t ector素的方法，通过在高温高压下仅使用水和乙醇作为溶剂，减少提取时间，提高提取产率，增强环境和人亲和力。 通过SWE（亚临界水提取），通过在含有水和30-100体积％乙醇的混合溶剂中加热中华白兰地根茎至80度的高温，从枸杞子根茎中提取鸢尾苷和t ector素。 ℃以上，优选为80〜200度。 C在高压条件下，如1-15MPa。
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39.发明授权오죽 추출물, 분획물 또는 이로부터 분리한 화합물을 포함하는 당뇨병 합병증 예방 또는 치료용 조성물 有权包含提取物，分离物和用于预防或治疗糖尿病并发症的NIGRA MUNRO的分离化合物的组合物
公开(公告)号：KR100824365B1
公开(公告)日：2008-04-22
申请号：KR1020060119768
申请日：2006-11-30
Applicant: 한국과학기술연구원
IPC: A61K36/899 , A61P3/10
Abstract: A composition comprising an extract of Phyllostachys nigra MUNRO, a fraction thereof or a compound isolated from the fraction is provided to inhibit accumulation of sorbitol, a fundamental cause of nephropathy and neuropathy shown as diabetic complications, by inhibiting aldose reductase, thereby being used as a pharmaceutical composition or a health food for preventing diseases related to the diabetic complications. A method for isolating a compound from Phyllostachys nigra MUNRO comprises the steps of: (a) extracting the Phyllostachys nigra MUNRO with ethanol and filtering the extract; (b) concentrating and freeze-drying the filtrate to obtain an extract; (c) fractionating an ethylacetate layer from the extract using a separation funnel; and (d) subjecting the fraction to silica gel column chromatography using CH2Cl2-MeOH as a solvent to obtain orientin, luteolin 6-C-(6''-O-transcaffeoylglucoside), tricetin 3',4',5'-trimethyl ether 7-O-b-D-glucopyranoside, tricine, p-coumaric acid or cis-coumaric acid. A pharmaceutical composition for preventing or treating diabetic retinopathy, diabetic neuropathy or diabetic nephropathy comprises the obtained compound as an effective ingredient.
Abstract translation: 提供了包含黑曲霉MUNRO提取物，其级分或从该级分分离的化合物的组合物，通过抑制醛糖还原酶来抑制山梨糖醇的积累，其是糖尿病并发症所示的肾病和神经病变的根本原因，因此被用作 药物组合物或用于预防与糖尿病并发症相关的疾病的保健食品。 一种从黑胫虫MUNRO中分离化合物的方法，包括以下步骤：（a）用乙醇萃取黑曲霉MUNRO，过滤提取物; （b）浓缩和冷冻滤液以获得提取物; （c）使用分液漏斗从提取物中分出乙酸乙酯层; 和（d）使用CH 2 Cl 2 -MeOH作为溶剂使级分进行硅胶柱色谱法，得到orientin，木犀草素6-C（6“-O-过氧基葡萄糖苷），三黄素3'，4'，5'-三甲基醚 7-ObD-吡喃葡萄糖苷，tricine，对香豆酸或顺式香豆酸。 用于预防或治疗糖尿病性视网膜病变，糖尿病性神经病变或糖尿病性肾病的药物组合物包含获得的化合物作为有效成分。
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公开(公告)号：KR101850308B1
公开(公告)日：2018-04-20
申请号：KR1020160100833
申请日：2016-08-08
Applicant: 한국과학기술연구원
Abstract: 본명세서에는홍국; 또는홍국추출물을유효성분으로포함하는장 건강개선용조성물이개시된다. 상기조성물은장내유익균의증식을촉진하고장내유해균의증식을억제하여장내균총을개선하고프로바이오틱스의효과를증강시켜주는효과가있다. 또한, 상기조성물은배변기능, 장기능을개선하여장 관련질환을개선시켜주는효과가있다.
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