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公开(公告)号:SI1027362T1
公开(公告)日:2005-12-31
申请号:SI9830783
申请日:1998-10-29
Applicant: ABBOTT LAB
Inventor: PHAN LY TAM , OR YAT SUN , CHU DANIEL T , PLATTNER JACOB J , CHEN YAN , CLARK RICHARD F
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公开(公告)号:DK0876388T3
公开(公告)日:2004-06-07
申请号:DK96936579
申请日:1996-10-17
Applicant: ABBOTT LAB
Inventor: OR YAT SUN , PHAN LY TAM , CHU DANIEL T , SPINA KENNETH P , HALLAS ROBERT , ELLIOTT RICHARD L
Abstract: Compounds, or pharmaceutically acceptable salts and esters thereof, of formulae (I); (II); (III) or (IV) wherein A, B, D and E, R , R and Z are specifically defined, having antibacterial activity, pharmaceutical compositions containing said compounds, treatment of antibacterial infections with such compositions, and processes for the preparation of the compounds.
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公开(公告)号:AU751448B2
公开(公告)日:2002-08-15
申请号:AU1288199
申请日:1998-10-29
Applicant: ABBOTT LAB
Inventor: PHAN LY TAM , OR YAT SUN , CHU DANIEL T , PLATTNER JACOB J , CHEN YAN , CLARK RICHARD F
IPC: A61K31/7042 , A61K31/7048 , A61P31/04 , C07H17/08 , A61K31/70
Abstract: Novel 2-halo-6-O-substituted ketolide derivatives and pharmaceutically acceptable salts and esters thereof having antibacterial activity having formula (I) or (II), compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier, a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for their preparation.
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公开(公告)号:CZ20001525A3
公开(公告)日:2000-10-11
申请号:CZ20001525
申请日:1998-10-29
Applicant: ABBOTT LAB
Inventor: PHAN LY TAM , OR YAT SUN , CHU DANIEL T , PLATTNER JACOB J , CHEN YAN , CLARK RICHARD F
IPC: A61K31/7042 , A61K31/7048 , A61P31/04 , C07H17/08
Abstract: Novel 2-halo-6-O-substituted ketolide derivatives and pharmaceutically acceptable salts and esters thereof having antibacterial activity having formula (I) or (II), compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier, a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for their preparation.
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公开(公告)号:NO20002190L
公开(公告)日:2000-06-29
申请号:NO20002190
申请日:2000-04-27
Applicant: ABBOTT LAB
Inventor: PHAN LY TAM , OR YAT SUN , CHU DANIEL T , PLATTNER JACOB J , CHEN YAN , CLARK RICHARD F
IPC: A61K31/7042 , A61K31/7048 , A61P31/04 , C07H17/08 , C07H
Abstract: Novel 2-halo-6-O-substituted ketolide derivatives and pharmaceutically acceptable salts and esters thereof having antibacterial activity having formula (I) or (II), compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier, a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for their preparation.
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公开(公告)号:NO20002190A
公开(公告)日:2000-06-29
申请号:NO20002190
申请日:2000-04-27
Applicant: ABBOTT LAB
Inventor: PHAN LY TAM , OR YAT SUN , CHU DANIEL T , PLATTNER JACOB J , CHEN YAN , CLARK RICHARD F
IPC: A61K31/7042 , A61K31/7048 , A61P31/04 , C07H17/08 , C07H
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公开(公告)号:BR9714269A
公开(公告)日:2000-04-18
申请号:BR9714269
申请日:1997-04-07
Applicant: ABBOTT LAB
Inventor: OR YAT SUN , PHAN LY TAM , CHU DANIEL T , SPINA KENNETH P , HALLAS ROBERT , ELLIOT RICHARD L , TUFANO MICHAEL
IPC: C07H17/00 , A61K31/00 , A61K31/70 , A61K31/7042 , A61K31/7048 , A61P31/00 , A61P31/04 , C07H17/08 , A61K31/71
Abstract: Compounds, or pharmaceutically acceptable salts and esters thereof, of the formula:wherein A, B, D and E, R1, R2, and Z are specifically defined, having antibacterial activity, pharmaceutical compositions containing said compounds, treatment of bacterial infections with such compositions, and processes for the preparation of the compounds.
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公开(公告)号:AU1288199A
公开(公告)日:1999-05-17
申请号:AU1288199
申请日:1998-10-29
Applicant: ABBOTT LAB
Inventor: PHAN LY TAM , OR YAT SUN , CHU DANIEL T , PLATTNER JACOB J , CHEN YAN , CLARK RICHARD F
IPC: A61K31/7042 , A61K31/7048 , A61P31/04 , C07H17/08 , A61K31/70
Abstract: Novel 2-halo-6-O-substituted ketolide derivatives and pharmaceutically acceptable salts and esters thereof having antibacterial activity having formula (I) or (II), compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier, a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for their preparation.
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公开(公告)号:CA2307788A1
公开(公告)日:1999-05-06
申请号:CA2307788
申请日:1998-10-29
Applicant: ABBOTT LAB
Inventor: PLATTNER JACOB J , CHU DANIEL T , OR YAT SUN , CHEN YAN , CLARK RICHARD F , PHAN LY TAM
IPC: A61K31/7042 , A61K31/7048 , A61P31/04 , C07H17/08 , A61K31/70
Abstract: Novel 2-halo-6-O-substituted ketolide derivatives and pharmaceutically acceptable salts and esters thereof having antibacterial activity having formula (I) or (II), compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier, a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for their preparation.
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公开(公告)号:MX9803692A
公开(公告)日:1998-09-30
申请号:MX9803692
申请日:1998-05-08
Applicant: ABBOTT LAB
Inventor: OR YAT SUN , PHAN LY TAM , CHU DANIEL T , SPINA KENNETH P , HALLAS ROBERT , ELLIOTT RICHARD L
Abstract: Compuestos, o sales farmacéuticamente aceptables y ésteres de los mismos, de las formulas (I); (II); (III) o (IV), en donde A, B, D, y E, R1, R2, y Z se definen específicamente, que tienen actividad antibacteriana; composiciones farmacéuticas que contienen a estos compuestos; tratamiento de infecciones antibacterianos con dichas composiciones, y procesos para la preparacion de los compuestos.
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