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    9-AMINO ERYTHROMYCIN DERIVATIVES WITH ANTIBACTERIAL ACTIVITY
    1.
    发明申请
    9-AMINO ERYTHROMYCIN DERIVATIVES WITH ANTIBACTERIAL ACTIVITY 审中-公开
    具抗静电活性的9-氨基嘌呤霉素衍生物

    公开(公告)号：WO02057286A3

    公开(公告)日：2003-11-06

    申请号：PCT/US0149634

    申请日：2001-12-27

    Applicant: ABBOTT LAB

    Inventor： MA ZHENKUN ,  PHAN LY TAM ,  ZHANG SUOMING ,  DJURIC STEVAN

    IPC: C07H17/08

    CPC classification number: C07H17/08

    Abstract: Compounds of formula (I), and formula (II), or therapeutically acceptable salts or prodrugs thereof are useful as antibacterial agents. Methods to make the compounds, compositions containing the compounds, and methods of treatment using the compounds are also disclosed.

    Abstract translation: 式（I）和式（II）的化合物或其治疗上可接受的盐或前药可用作抗菌剂。 还公开了使化合物，含有该化合物的组合物和使用该化合物的处理方法的方法。

    6-O-ALKYL-2-NOR-2-SUBSTITUTED KETOLIDE DERIVATIVES
    2.
    发明申请
    6-O-ALKYL-2-NOR-2-SUBSTITUTED KETOLIDE DERIVATIVES 审中-公开
    6-O-烷基-2-异-2-取代的硬脂酸衍生物

    公开(公告)号：WO0140241A3

    公开(公告)日：2001-12-13

    申请号：PCT/US0032767

    申请日：2000-12-01

    Applicant: ABBOTT LAB

    Inventor： PHAN LY TAM ,  OR YAT SUN ,  MA ZHENKUN

    IPC: A61K31/7052 ,  A61K31/7056 ,  A61P31/04 ,  C07H17/08 ,  C07H17/00

    CPC classification number: C07H17/08

    Abstract: The present invention relates to 6-O-alkyl-2-nor-2-substituted ketolide compound or a derivative thereof, a composition comprising the compound and a suitable carrier, a method of preparing the compound, and a method of treatment and prevention of in mammals comprising administering said compound.

    Abstract translation: 本发明涉及6-O-烷基-2-间-2-取代的酮内酯化合物或其衍生物，包含该化合物和合适的载体的组合物，该化合物的制备方法和一种治疗和预防 包括施用所述化合物的哺乳动物。

    C-2 MODIFIED ERYTHROMYCIN DERIVATIVES
    3.
    发明申请
    C-2 MODIFIED ERYTHROMYCIN DERIVATIVES 审中-公开
    C-2改性的红霉素衍生物

    公开(公告)号：WO0069875A9

    公开(公告)日：2002-02-21

    申请号：PCT/US0012202

    申请日：2000-05-04

    Applicant: ABBOTT LAB

    Inventor： MA ZHENKUN ,  OR YAT SUN ,  PHAN LY TAM ,  SUOMING ZHANG ,  CLARK RICHARD F

    IPC: A61K31/7048 ,  A61P31/04 ,  C07H17/08 ,  A61K31/70

    CPC classification number: C07H17/08

    Abstract: A compound having the formula selected from the group consisting of a compound of formula (I), a compound of formula (II), and a compound of formula (III) as well as pharmaceutically acceptable salts, esters, solvates, metabolites, and prodrugs thereof, are useful in treating bacterial infections. Also provided are pharmaceutically acceptable compositions, methods of treating bacterial infections, and processes for the preparation of the compounds.

    Abstract translation: 具有选自式（I）化合物，式（II）化合物和式（III）化合物以及其药学上可接受的盐，酯，溶剂合物，代谢物和前药的化合物的化合物 可用于治疗细菌感染。 还提供了药学上可接受的组合物，治疗细菌感染的方法和化合物的制备方法。

    8.
    发明专利
    未知

    公开(公告)号：TR200001142T2

    公开(公告)日：2000-09-21

    申请号：TR200001142

    申请日：1998-10-29

    Applicant: ABBOTT LAB

    Inventor： PHAN LY TAM ,  OR YAT SUN ,  CHU DANIEL T ,  PLATINER JACOB J ,  CHEN YAN ,  CLARK RICHARD F

    IPC: A61K31/7042 ,  A61K31/7048 ,  A61P31/04 ,  C07H17/08 ,  A61K31/70

    Abstract: Novel 2-halo-6-O-substituted ketolide derivatives and pharmaceutically acceptable salts and esters thereof having antibacterial activity having formula (I) or (II), compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier, a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for their preparation.

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