公开(公告)号：JPS6296432A

公开(公告)日：1987-05-02

申请号：JP23614185

申请日：1985-10-22

Applicant: AGENCY IND SCIENCE TECHN

Inventor： SUZUKI OSAMU ,  YOKOCHI TOSHIHIRO ,  NAKANE TAKASHI

IPC: A61K31/20 ,  A23L1/30 ,  A61K8/04 ,  A61K8/30 ,  A61K8/36 ,  A61K8/37 ,  A61K8/60 ,  A61K8/72 ,  A61K8/73 ,  A61K31/23 ,  A61K47/40 ,  A61P3/06 ,  A61P9/00 ,  A61P9/10 ,  A61P9/12 ,  A61P13/02 ,  A61P15/00 ,  A61P37/08 ,  A61Q19/00 ,  C07C53/126 ,  C07C69/22 ,  C08B37/16 ,  C11B15/00

Abstract: PURPOSE:To obtain a composition containing a higher fatty acid or its ester and having excellent dispersibility in water, by adding a higher fatty acid or its ester in liquid state to cyclodextrin and mixing the product. CONSTITUTION:A water-dispersible composition containing a higher fatty acid or its ester is produced by adding a higher fatty acid (e.g. gamma-linolenic acid) or its ester in liquid state to cyclodextrin and mixing the product. A higher fatty acid or its ester is an oily substance immiscible with water. The oily substance can be uniformly dispersed in various aqueous solutions or aqueous slurries and in some oily substances by converting the substance to the present composition. Accordingly, the present composition can be utilized in various fields taking advantage of the physiological activity or pharmacological activity of the higher fatty acid or its ester. The amount of the higher fatty acid or its ester is 1-30pts.wt. per 100pts.wt. of cyclodextrin.

公开(公告)号：JPS61227790A

公开(公告)日：1986-10-09

申请号：JP6766985

申请日：1985-03-30

Applicant: AGENCY IND SCIENCE TECHN ,  NITTO ELECTRIC IND CO

Inventor： SUZUKI OSAMU ,  YOKOCHI TOSHIHIRO ,  NINOMIYA YASUO ,  KOMATA TETSUO

IPC: C12P7/64 ,  C11B1/02 ,  C11B1/10

Abstract: PURPOSE:To enable the extraction of glyceride oil in high yield, without causing the contamination with impurities, by adjusting the water content of microbial cells separated from a medium below a specific level and extracting the cells with an organic solvent. CONSTITUTION:Glyceride oil existing in microbial cells separated from a medium is extracted after drying the cell to a water-content of

公开(公告)号：JPS61179233A

公开(公告)日：1986-08-11

申请号：JP1773685

申请日：1985-02-02

Applicant: AGENCY IND SCIENCE TECHN

Inventor： HINO SEIICHI ,  KOURA KOJI ,  SUZUKI OSAMU

IPC: C08G73/00 ,  C08G73/10 ,  C08J5/24

Abstract: PURPOSE:To obtain a polyamide composite material excellent in mechanical and thermal properties, by increasing the flexibility of prepregs by impregnating fiber reinforcements with a monomer composition comprising an aromatic tetracarboxylic acid, an o-ethylaniline/formaldehyde condensate and an agent for introducing terminal functional groups. CONSTITUTION:A prepreg obtained by impregnating a fiber reinforcement with a monomer composition comprising an aromatic tetracarboxylic acid or its derivative (a), an o-ethylaniline/formaldehyde condensate (b) and an agent (c) for introducing terminal functional groups. Exemplary of component (a) used are acids such as pyromellitic or 3,3',4,4'-benzophenonetetracarboxylic acid or their derivatives such as lower alkyl esters and dianhydrides. Exemplary of component (c) are unsaturated dicarboxylic acids or their derivatives (e.g., maleic acid, itaconic acid and their alkyl esters) and unsaturated group- containing amino compounds (e.g., p-aminophenylacetylene).

公开(公告)号：JPS61149054A

公开(公告)日：1986-07-07

申请号：JP27015984

申请日：1984-12-21

Applicant: AGENCY IND SCIENCE TECHN ,  RIKEN VITAMIN CO

Inventor： SUZUKI OSAMU ,  YOKOCHI TOSHIHIRO ,  MUROI KOJI

Abstract: PURPOSE:To provide the titled composition effective to prevent the health disturbance and trophopathy of cat, by adding the cell of microorganism of Mortierella genus containing an oil or fat containing gamma-linoleic acid. CONSTITUTION:A microbial strain belonging to Mortierella genus and capable of producing lipid having high gamma-linoleic acid content (e.g. Mortierella isabellina) is cultured in a hydrocarbon medium or a molasses medium, etc. to obtain the cell of Mortierella containing 20-50wt% oil or fat containing gamma-linoleic acid. The microbial cells are added to a cat food in an amount to give a gamma- linoleic acid content of 0.01-1.0wt%.

公开(公告)号：JPH11137255A

公开(公告)日：1999-05-25

申请号：JP30772197

申请日：1997-11-10

Applicant: AGENCY IND SCIENCE TECHN

Inventor： IMAMURA TORU ,  ASADA SHINKO ,  OKA SHUICHI ,  SUZUKI OSAMU ,  YONEDA ATSUKO ,  OTA KEIKO ,  ODA HIROKO ,  MIYAGAWA KAZUKO ,  ORIGASA NORIKO ,  ASADA TOMOHARU ,  KOJIMA TETSUTO

IPC: C12N15/09 ,  A61K31/715 ,  A61K38/00 ,  A61K38/17 ,  A61P9/08 ,  A61P9/10 ,  A61P17/00 ,  A61P17/02 ,  A61P17/14 ,  A61P25/00 ,  A61P25/16 ,  A61P25/28 ,  A61P35/00 ,  A61P43/00 ,  C07K14/47 ,  C07K14/50 ,  C07K19/00 ,  C12N1/21 ,  C12N5/00 ,  C12N5/10 ,  C12N15/00 ,  C12P21/02 ,  C12R1/19 ,  C12R1/91

Abstract: PROBLEM TO BE SOLVED: To obtain the subject protein excellent in stability such as heat resistance, acid resistance, alkali resistance and resistance to a proteolytic enzyme by allowing a heparin-bondable protein to bind to a sugar chain with a covalent bond. SOLUTION: The subject protein is obtained by allowing a heparin-bondable protein having an amino acid sequence, etc., of the formula to bind to a sugar chain (e.g. a sulfated polysaccharide, a glycosaminoglycan, an N-type sugar chain and an O-type sugar chain) with a covalent bond through a peptide, etc., capable of receiving the addition of the sugar chain. The method for producing the subject protein comprises connecting a cDNA encoding a peptide capable of receiving the addition of any of these sugar chains to the cDNA of the heparin-bondable protein, and allowing the gene product of the connected cDNA to be produced by an animal cell.

公开(公告)号：JPH02207792A

公开(公告)日：1990-08-17

申请号：JP2707989

申请日：1989-02-06

Applicant: AGENCY IND SCIENCE TECHN

Inventor： NAKAHARA HARUO ,  SUZUKI OSAMU ,  YOKOCHI TOSHIHIRO ,  YAMAOKA MASAKAZU ,  KAMISAKA YASUSHI

IPC: C12P7/64 ,  C12N11/02

Abstract: PURPOSE:To efficiently produce 13-hydroperoxy-gamma-linolenic acid by treating gamma-linolenic acid with soybean lipoxygenase in the presence of a specific buffer solution and a surfactant. CONSTITUTION:gamma-Linolenic acid is treated with soybean lipoxygenase in a two- phase system of hexane-boric acid buffer solution adjusted to pH >=9 in the presence of a surfactant. Consequently, gamma-linolenic acid is converted into 13- hydroxyperoxy-gamma-linolenic acid. Second oxygen addition of prepared 13- hydroxyperoxy-gamma-linolenic acid is prevented by immobilizing soybean lipoxygenase to chitosan and highly concentrated 13-hydroxyperoxy-gamma-linolenic acid is obtained. Immobilization of soybean lipoxygenase to chitosan is carried out through glutaraldehyde.

公开(公告)号：JPH0288676A

公开(公告)日：1990-03-28

申请号：JP23977788

申请日：1988-09-27

Applicant: AGENCY IND SCIENCE TECHN

Inventor： HINO SEIICHI ,  SATO SHOICHI ,  KOURA KOJI ,  SUZUKI OSAMU

IPC: C08K5/41 ,  C08F290/00 ,  C08F290/14 ,  C08G73/10 ,  C08L79/08

Abstract: PURPOSE:To obtain the title composition capable of providing polyimide resin having excellent heat resistance and moldability by heat curing and suitable for fiber reinforced composite material by blending a specific imide oligomer with 4,4'-bis(2-allyl phenol)sulfone. CONSTITUTION:The aimed composition obtained by blending (A) an imide oligomer obtained by reacting an aromatic tetracarboxylic acid (derivative) (e.g., pyromellitic acid) with a condensed product of o-ethylaniline with formaldehyde and maleic acid (derivative) with (B) 4,4'-bis(2-allyl phenol)sulfone in an equivalent of 0.1-10, preferably 0.3-3 based on 1 equivalent component A.

公开(公告)号：JPH0288675A

公开(公告)日：1990-03-28

申请号：JP23977688

申请日：1988-09-27

Applicant: AGENCY IND SCIENCE TECHN

Inventor： HINO SEIICHI ,  SATO SHOICHI ,  KOURA KOJI ,  SUZUKI OSAMU

IPC: C08K5/13 ,  C08F290/00 ,  C08F290/14 ,  C08G73/10 ,  C08L79/08

Abstract: PURPOSE:To obtain imide oligomer composition having excellent heat resistance and moldability and suitable for molded article of fiber reinforced cross-oriented laminated, etc., by blending specific two kind of functionalizing agents with alkenyl phenols. CONSTITUTION:The aimed composition obtained by blending (A) imide oligomer obtained by reacting A1: aromatic tetracarboxylic acid (derivative) (e.g., pyromellitic acid) with A2: condensed product of o-ethylaniline with formaldehyde and A3: maleic acid (derivative) and (B) imide oligomer obtained by reacting B1: component A1 with B2: component A2 and B3: nadic acid (derivative) or (C) polynadinimide obtained by C1: condensed product of o-ethylaniline with formaldehyde with C2: component B3 and (D) alkenyl phenol in equivalent ratio of the component A to the component B or component C of 40:60-90:10 and ratio of component D to 1 equivalent component A of 0.1-10.

公开(公告)号：JPS63258926A

公开(公告)日：1988-10-26

申请号：JP9196887

申请日：1987-04-16

Applicant: AGENCY IND SCIENCE TECHN

Inventor： HINO SEIICHI ,  SATO SHOICHI ,  KOURA KOJI ,  SUZUKI OSAMU

IPC: C08G73/10 ,  C07D209/48 ,  C08F290/00 ,  C08F299/02 ,  C08K5/3415 ,  C08L79/08

Abstract: PURPOSE:To obtain a solvent-soluble imide oligomer composition outstanding in storage stability and molding processability, capable of conversion into a highly heat-resistant polyimide by heating, by blending each specific imide oligomer and maleimide. CONSTITUTION:The objective composition can be obtained by blending (A) an imide oligomer prepared by reaction between A1: an aromatic tetracarboxylic acid or its derivative (pref. dianhydride), A2: a polyamine consisting mainly of condensate from O-ethylaniline and formaldehyde (pref. tri- or higher amine accounting for

公开(公告)号：JPS63248828A

公开(公告)日：1988-10-17

申请号：JP7978087

申请日：1987-04-02

Applicant: AGENCY IND SCIENCE TECHN

Inventor： HINO SEIICHI ,  SATO SHOICHI ,  KOURA KOJI ,  SUZUKI OSAMU

IPC: C07D209/48 ,  C08F290/00 ,  C08F299/02 ,  C08G73/10 ,  C08L79/08

Abstract: PURPOSE:To obtain the title composition of excellent storage stability, moldability and heat resistance, to be used in composite materials and adhesives by adding 2 different kinds of oligomers, resulting from reactions of an aromatic tetracarboxylic acid or its derivative and a polyamine with different kinds of agents to activate chain terminals respectively. CONSTITUTION:The subject composition is obtained by mixing (A) an imide oligomer resulting from the reaction of nadic acid with an aromatic tetracarboxylic acid or its derivative such as pyromellitic acid and a polyamine from o-ethylaniline and formaldehyde in an organic solvent such as N,N- dimethylformamide and (B) another imide oligomer from the reaction with maleic acid at an A:B equivalent ratio of 60:40-10:90.