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公开(公告)号：ES2151921T3
公开(公告)日：2001-01-16
申请号：ES94902676
申请日：1993-12-04
Applicant: BASF AG
Inventor： HAUPT ANDREAS , JANSSEN BERND , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , ROMERDAHL CYNTHIA
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公开(公告)号：DE69425882D1
公开(公告)日：2000-10-19
申请号：DE69425882
申请日：1994-03-19
Applicant: BASF AG
Inventor： JANSSEN BERND , KLING ANDREAS , MUELLER STEFAN , RITTER KURT , SCHLECKER RAINER , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , TRAUGOTT ULRICH
IPC: C07D295/08 , A61K31/34 , A61K31/341 , A61K31/357 , A61K31/36 , A61K31/40 , A61K31/403 , A61K31/41 , A61K31/42 , A61K31/421 , A61K31/4245 , A61K31/425 , A61K31/426 , A61K31/433 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4412 , A61K31/4418 , A61K31/445 , A61K31/451 , A61K31/47 , A61K31/495 , A61K31/496 , A61P35/00 , C07D207/32 , C07D207/333 , C07D209/52 , C07D211/14 , C07D213/30 , C07D215/14 , C07D261/08 , C07D261/18 , C07D263/14 , C07D263/32 , C07D271/06 , C07D271/10 , C07D277/24 , C07D285/12 , C07D295/092 , C07D307/42 , C07D307/58 , C07D317/58 , C07D317/66 , C07D333/06 , C07D333/16 , C07D413/12 , C07D417/12 , C07D521/00 , C07F9/6509
Abstract: This invention relates to 1-amino-3-phenoxy-propane-derivatives of formula 1: 1 (in which A, B, R, Rx, X and Z are defined as in the specification described) and methods for their preparation. These compounds may be used as modulators of multidrug resistance in cancer chemotherapy and for circumvention of resistance in the treatment of malaria.
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公开(公告)号：SG69983A1
公开(公告)日：2000-01-25
申请号：SG1996009082
申请日：1993-05-10
Applicant: BASF AG
Inventor： EMILING FRANZ , HAUPT ANDREAS , ROMERDAHL CYNTHIA
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公开(公告)号：NO305554B1
公开(公告)日：1999-06-21
申请号：NO960632
申请日：1996-02-16
Applicant: BASF AG
Inventor： KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BRANA MIGUEL FERNANDEZ , QIAN XIAO-DONG , BOUSQUET PETER , BERLANGA JOSU MARIA CASTELLANO , MOSET MARINA MORAN , VEGA MARIA JESUS PEREZ DE
IPC: A61K31/47 , A61K31/473 , A61P35/00 , C07D221/14 , A61K31/435
Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula 1. A compound of the Formula wherein X, X', X'' and X''', A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
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公开(公告)号：DK0642530T3
公开(公告)日：1998-10-26
申请号：DK93909931
申请日：1993-05-10
Applicant: BASF AG
Inventor： HAUPT ANDREAS , EMLING FRANZ , ROMERDAHL CYNTHIA
IPC: A61K38/00 , A61K38/08 , A61P35/00 , A61P35/02 , C07K5/062 , C07K5/08 , C07K5/083 , C07K5/087 , C07K5/10 , C07K5/103 , C07K5/107 , C07K7/06 , A61K37/02 , A61K38/04
Abstract: Novel derivates of dolastatin of formula (I) in which R , R , A, B, D, E, F, G, K, X, t, u, v, and w have the meanings stated in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.
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Patent Agency Ranking
公开(公告)号：DK0714387T3
公开(公告)日：1998-10-12
申请号：DK94924854
申请日：1994-08-08
Applicant: BASF AG
Inventor： KEILHAUER GERHARD , ROMERDAHL CYNTHIA , FERNANDEZ BRANA MIGUEL , QIAN XIAO-DONG , BOUSQUET PETER , CASTELLANO BERLANGA JOSE MARIA , MORAN MOSET MARINA , PEREZ DE VEGA MARIA JESUS
IPC: A61K31/47 , A61K31/473 , A61P35/00 , C07D221/14 , A61K31/435
Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula 1. A compound of the Formula wherein X, X', X'' and X''', A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
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公开(公告)号：NO975710D0
公开(公告)日：1997-12-05
申请号：NO975710
申请日：1997-12-05
Applicant: BASF AG
Inventor： HAUPT ANDREAS , EMLING FRANZ , ROMERDAHL CYNTHIA
Abstract: Novel compounds of the formulaR1R2N-CHX-CO-A-B-D-(E)s-(F)t-(G)U-KIin which R1, R2, A, B, D, E, F, G, K, X, s, t, and u have the meanings stated in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.
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公开(公告)号：IN177307B
公开(公告)日：1996-12-28
申请号：IN318MA1993
申请日：1993-05-11
Applicant: BASF AG
Inventor： HAUPT ANDREAS , EMLING FRANZ , ROMERDAHL CYNTHIA
IPC: C07K7/00
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公开(公告)号：ZA9406196B
公开(公告)日：1996-02-19
申请号：ZA9406196
申请日：1994-08-17
Applicant: BASF AG
Inventor： KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BRANA MIGUEL FERNANDEZ , QIAN XIAO-DONG , BOUSQUET PETER , BERLANGA JOSE MARIA CASTELLANO , MOSET MARINA MORAN , VEGA MARIA JESUS PREZ DE
IPC: A61K31/47 , A61K31/473 , A61P35/00 , C07D221/14 , A61K , C07D
CPC classification number: C07D221/14
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公开(公告)号：HU9501754D0
公开(公告)日：1995-08-28
申请号：HU9501754
申请日：1993-12-04
Applicant: BASF AG
Inventor： JANSSEN BERND , HAUPT ANDREAS , ROMERDAHL CYNTHIA , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , BARLOZZARI TERESA , QIAN XIAO-DONG
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