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公开(公告)号:AU517876B2
公开(公告)日:1981-09-03
申请号:AU2705777
申请日:1977-07-15
Applicant: HOECHST AG
Inventor: BARTMANN W , LERCH U , TEUFEL H , SCHOLKENS B , BECK G
IPC: C07D339/08 , A61K31/19 , A61K31/215 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07D317/72 , C07D339/06 , C07C177/00 , C07C121/46 , C07D319/08 , C07D411/08
Abstract: What is disclosed are prostaglandin-analogous cyclopentane derivatives of the formula I wherein R1 is hydrogen or a linear or branched, saturated or unsaturated aliphatic or cycloaliphatic radical having from 1 to 8 carbon atoms, or an araliphatic radical having from 7 to 9 carbon atoms, or a physiologically tolerable metal, NH4 or substituted ammonium ion derived from a primary, secondary or tertiary amine; R2 is a linear or branched, saturated or unsaturated aliphatic hydrocarbon radical having from 1 to 8 carbon atoms; R3 is hydrogen or a R4CO group wherein R4 is a hydrogen atom or a linear or branched alkyl group having up to 10 carbon atoms; A is a saturated, linear or branched alkylene group having from 2 to 5 carbon atoms, and a process for the manufacture thereof.
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公开(公告)号:ZA8002011B
公开(公告)日:1981-04-29
申请号:ZA8002011
申请日:1980-04-03
Applicant: HOECHST AG
Inventor: BECK G , LERCH U , SCHOELKENS B , RUPP R
IPC: C07D333/16 , A61K31/34 , A61K31/341 , A61K31/38 , A61K31/381 , A61K31/557 , A61K31/5575 , A61P7/02 , A61P9/08 , A61P9/10 , A61P9/12 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07D307/42 , C07D307/937 , C07C , A61K
CPC classification number: C07D307/937 , C07C405/00 , Y10S514/822
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公开(公告)号:ZA7903992B
公开(公告)日:1980-08-27
申请号:ZA7903992
申请日:1979-08-03
Applicant: HOECHST AG
Inventor: LERCH U , BARTMANN W , BECK G , KONZ E
IPC: A61K31/23 , A61K31/19 , A61K31/34 , A61K31/341 , A61K31/38 , A61K31/381 , A61P43/00 , C07C45/29 , C07C45/60 , C07C47/267 , C07C49/743 , C07C49/757 , C07C67/00 , C07C401/00 , C07C405/00 , C07D307/34 , C07D307/58 , C07D307/935 , C07D319/06 , C07D333/16 , C07C
CPC classification number: C07D307/935 , C07C45/29 , C07C45/60 , C07C47/267 , C07C49/743 , C07C49/757 , C07C405/00 , C07D319/06 , Y10S514/822
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公开(公告)号:AU502124B2
公开(公告)日:1979-07-12
申请号:AU8326575
申请日:1975-07-22
Applicant: HOECHST AG
Inventor: BECK G , BARTMANN W , LERCH U , SCHOLKENS B
IPC: A61K31/21 , A61K31/557 , A61K31/5575 , A61P43/00 , C07C67/00 , C07C271/28 , C07C401/00 , C07C405/00 , C07D307/935 , C07C177/00 , C07D309/12 , C07D307/93 , C07C131/00 , C07D307/40 , C07D407/12 , C07D407/14 , C07C125/06 , A61K31/19 , A61K31/335 , A61K31/34 , A61K31/39
Abstract: The present invention relates to new analogues which do not occur naturally of prostanoic acids of the formula I I The compounds of the invention have spasmogenic, bronchodilatant and hypotensive properties. Therefore, they can be used as medicaments. This invention also relates to a process for preparing the compounds of the invention.
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公开(公告)号:ZA7800368B
公开(公告)日:1979-01-31
申请号:ZA7800368
申请日:1978-01-20
Applicant: HOECHST AG
Inventor: LERCH U , BARTMANN W , SCHOELKENS B , BECK G , TEUFEL H
IPC: C07D317/30 , A61K31/215 , A61K31/335 , A61K31/34 , A61K31/341 , A61K31/357 , A61P9/12 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07D307/58 , A61K37/24 , C07C177/00
CPC classification number: C07C405/00
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公开(公告)号:SE7800688L
公开(公告)日:1978-07-22
申请号:SE7800688
申请日:1978-01-19
Applicant: HOECHST AG
Inventor: BARTMANN W , BECK G , LERCH U , TEUFEL H , SCHOLKENS B
IPC: C07D307/42 , A61K31/20 , A61K31/34 , A61K31/341 , A61P9/12 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07C177/00
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公开(公告)号:DK29478A
公开(公告)日:1978-07-22
申请号:DK29478
申请日:1978-01-20
Applicant: HOECHST AG
Inventor: BARTMANN W , BECK G , LERCH U , TEUFEL H , SCHOELKENS B
IPC: C07D307/42 , A61K31/20 , A61K31/34 , A61K31/341 , A61P9/12 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07C
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公开(公告)号:DK282677A
公开(公告)日:1977-12-26
申请号:DK282677
申请日:1977-06-24
Applicant: HOECHST AG
Inventor: BARTMANN W , BECK G , LERCH U , SCHOELKENS B
IPC: A61K31/215 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07C
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公开(公告)号:DK546176A
公开(公告)日:1977-06-06
申请号:DK546176
申请日:1976-12-03
Applicant: HOECHST AG
Inventor: BARTMANN W , BECK G , LERCH U , SEEGER K , TEUFEL H
IPC: A61K9/00 , A61K31/20 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07D307/935 , C07F9/40 , C07C
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公开(公告)号:SE7606318L
公开(公告)日:1976-12-06
申请号:SE7606318
申请日:1976-06-03
Applicant: HOECHST AG
Inventor: BARTMANN W , BECK G , REUSCHLING D-B , SEEGER K , TEUFEL H
IPC: C07D333/16 , A61K31/557 , A61K31/5575 , A61P1/04 , A61P7/02 , A61P7/10 , A61P9/12 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07D307/935 , C07D333/00 , C07D333/32 , C07D333/64 , C07D333/78 , C07D409/12 , C07D409/14 , C07F9/54 , C07C177/00
Abstract: The present invention relates to thienyl-prostaglandin derivatives and to a process for their manufacture. The compounds according to the invention have valuable pharmaceutical properties.
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