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公开(公告)号:DE102005015294A1
公开(公告)日:2006-10-05
申请号:DE102005015294
申请日:2005-04-01
Applicant: LEICA MICROSYSTEMS
Inventor: KNEBEL WERNER
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公开(公告)号:DE102005027077A1
公开(公告)日:2006-05-11
申请号:DE102005027077
申请日:2005-06-11
Applicant: LEICA MICROSYSTEMS
Inventor: KNEBEL WERNER , HOFFMANN JUERGEN
Abstract: Microscope has an illumination unit (3) producing light beams to illuminate a sample in an illuminating plane lying at an angle different from 90[deg] to the detection unit (29). Preferred Features: The illumination plane lies at an angle of less than 80[deg] or more than 100[deg] to the detection unit. The illumination plane rotates relative to the sample, preferably about an axis of rotation aligned in the detection unit. The illumination unit contains an adjustable beam deviating unit.
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公开(公告)号:DE102004049770A1
公开(公告)日:2006-04-13
申请号:DE102004049770
申请日:2004-10-12
Applicant: LEICA MICROSYSTEMS
Inventor: KNEBEL WERNER , BURGER GABRIELE
IPC: G02B21/00
Abstract: The device has a reflective and/or scattered light suppressing device (40) arranged in an optical path between selection and detection devices to suppress reflective and scattered light of an illuminating light of a scan microscope. The device (40) has a graded filter (41) that includes long pass filters with different characteristics. The long pass filters are replaceable and arranged one after another on a common substrate. An independent claim is also included for a scan microscope with a device for selecting and detecting spectral regions of light rays.
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公开(公告)号:DE102004032952A1
公开(公告)日:2006-01-26
申请号:DE102004032952
申请日:2004-07-07
Applicant: LEICA MICROSYSTEMS
Inventor: KNEBEL WERNER , SCHROEDER JAN
Abstract: Disclosed is a method for analyzing biological samples by means of a scanning microscope. According to said method, at least one screen dot is repeatedly and successively illuminated with a manipulating light beam and an exciting light beam. The interval between the time of illumination with the manipulating light beam and the time of illumination with the exciting light beam is modified, and the fluorescent light yield is measured in accordance with said interval.
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公开(公告)号:DE102004030208B3
公开(公告)日:2005-12-15
申请号:DE102004030208
申请日:2004-06-22
Applicant: LEICA MICROSYSTEMS
Inventor: HOFFMANN JUERGEN , KNEBEL WERNER , MOELLMANN KYRA
Abstract: An optical device comprising an acousto-optical component is arranged in the illumination beam path and in the observation beam path. A splitter/combiner splits/combines the illumination beam path and the observation beam path. An independent claim is included for an optical device.
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公开(公告)号:DE10335466B4
公开(公告)日:2005-09-01
申请号:DE10335466
申请日:2003-08-02
Applicant: LEICA MICROSYSTEMS
Inventor: STORZ RAFAEL , KNEBEL WERNER
Abstract: The scanning microscope (1) has an incoupling apparatus (31) with which light (33) other than the light (17) proceeding from the sample (7) is coupled into the detection beam path and conveyed to the detector (21). A closure apparatus automatically closes off the incoupling apparatus from the outside, in largely light-tight fashion, when the light guide (37) guiding the other light to the incoupling apparatus is removed. An independent claim is also included for confocal scanning microscope.
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公开(公告)号:DE10337296A1
公开(公告)日:2005-03-03
申请号:DE10337296
申请日:2003-08-14
Applicant: LEICA MICROSYSTEMS
Inventor: KNEBEL WERNER , MOELLMANN KYRA
Abstract: Scanning microscope has a light source which generates an illumination light beam for illumination of a sample, with means for spectrally splitting and at least partially screening the detection light emitted by the sample. The illuminating light beam travels through the spectral splitting and screening means.
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公开(公告)号:DE10243449A1
公开(公告)日:2004-03-25
申请号:DE10243449
申请日:2002-09-19
Applicant: LEICA MICROSYSTEMS
Inventor: KNEBEL WERNER
Abstract: CARS-microscopy (coherent anti-Stokes Raman scattering) microscope has means for generation of a pumped light beam and a Stokes light beam that can be coaxially guided through the microscope optics onto a sample. A detector is further provided for detection light from the sample. The means for generation of the pumped and Stokes light beam comprise a laser and a micro-structured optical element that spectrally broadens the laser light. An Independent claim is made for a CARS-microscopy method.
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公开(公告)号:DE10132638A1
公开(公告)日:2003-01-16
申请号:DE10132638
申请日:2001-07-05
Applicant: LEICA MICROSYSTEMS
Inventor: ENGELHARDT JOHANN , KNEBEL WERNER
IPC: G02B21/00
Abstract: A scanning microscope examines a specimen (31). An optical component (89) has a characteristic that depends on wavelengths. A device uses wavelengths to perform detection that picks up measurement values in two wavelength ranges each characterized by spectral width and position. An Independent claim is also included for a method for using wavelengths to detect light emitted from a specimen by means of a scanning microscope.
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公开(公告)号:DE10055176A1
公开(公告)日:2002-05-23
申请号:DE10055176
申请日:2000-11-08
Applicant: LEICA MICROSYSTEMS
Inventor: ENGELHARDT JOHANN , KNEBEL WERNER
Abstract: An arrangement for visual and quantitative three-dimensional examination of specimens, having a stereomicroscope (2). The stereomicroscope defines a first and a second observation beam path (4, 5), by way of which a specimen (6) to be examined can be visually observed. A confocal scanning device (1) is connected to the stereomicroscope (1) in such a way that a scanning beam path (3) defined by the confocal scanning device (1) scans the specimen (6) that is to be examined and in that context acquires data for a three-dimensional visual depiction of the specimen (6).
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