Patent search ap:("PHARMACYCLICS INC") AND inv:"CHEN WEI" Page 4

31.

发明专利
ИНГИБИТОРЫ ТИРОЗИНКИНАЗЫ БРУТОНА 未知

公开(公告)号：EA017865B1

公开(公告)日：2013-03-29

申请号：EA200901313

申请日：2008-03-27

Applicant: PHARMACYCLICS INC

Inventor： HONIGBERG LEE , VERNER ERIK , BUGGY JOSEPH J , LOURY DAVID , CHEN WEI

IPC: A61K31/52 , A61K31/519 , A61P29/00 , A61P35/00 , C07D253/06 , C07D473/34 , C07D487/04

Abstract: Впатентеописанынеобратимыеингибиторыкиназ, способысинтезатакихнеобратимыхингибиторови способыприменениятакихнеобратимыхингибиторовдлялеченияболезней. Описанытакжеметодыанализаи системыдляопределениясоответствующегонеобратимогоингибиторабелка, включаякиназу.

32.

发明专利
PURINONE COMPOUNDS AS KINASE INHIBITORS 未知

公开(公告)号：CA2863140C

公开(公告)日：2016-10-18

申请号：CA2863140

申请日：2013-01-30

Applicant: PHARMACYCLICS INC

Inventor： YAN SHUNQI , WANG LONGCHENG , FRYE LEAH LYNN , CHEN WEI , LOURY DAVID J

IPC: C07D473/34 , A61K31/522 , A61P37/06

Abstract: Disclosed herein are compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. In addition, reversible inhibitors of Btk are also described. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.

33.

发明专利
未知

公开(公告)号：TN2015000174A1

公开(公告)日：2016-10-03

申请号：TN2015000174

申请日：2015-05-06

Applicant: PHARMACYCLICS INC

Inventor： CHEN WEI , LOURY DAVID J , WANG LONGCHENG

IPC: A61K31/519 , A61P29/00 , A61P35/00 , A61P37/00 , C07D487/04

34.

发明专利
作為激酶抑制劑的吡咯並嘧啶化合物未知

公开(公告)号：HK1215253A1

公开(公告)日：2016-08-19

申请号：HK16103201

申请日：2016-03-18

Applicant: PHARMACYCLICS INC

Inventor： CHEN WEI , LOURY DAVID J , WANG LONGCHENG

IPC: C07D20060101 , A61K20060101 , A61P20060101

35.

发明专利
Inhibitors of Bruton's tyrosine kinase 未知

公开(公告)号：AU2010306921B2

公开(公告)日：2015-08-13

申请号：AU2010306921

申请日：2010-10-12

Applicant: PHARMACYCLICS INC

Inventor： CHEN WEI , LOURY DAVID J , MODY TARAK D , VERNER ERIK , SMYTH MARK STEPHEN , LUO WENCHEN

IPC: C07D401/04 , A61K31/519 , A61P19/02 , A61P19/10 , C07D401/14 , C07D487/04

Abstract: Described herein are kinase inhibitor compounds, methods for synthesizing such inhibitors, and methods for using such inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate inhibitor of a protein, including a kinase.

36.

发明专利
Compuestos derivados de pirrolopirimidina, como inhibidores de quinasas; composicion farmaceutica que los comprende, util para el tratamiento de una enfermedad o condicion autoinmune tal como artritis reumatoide o lupus, y para el tratamiento de una enfermedad o condicion heteroinmune o inflamatoria. 未知

公开(公告)号：CL2015001268A1

公开(公告)日：2015-07-10

申请号：CL2015001268

申请日：2015-05-12

Applicant: PHARMACYCLICS INC

Inventor： CHEN WEI , LOURY DAVID J , WANG LONGCHENG

IPC: C07D487/04 , A61K31/519 , A61P29/00 , A61P35/00 , A61P37/00

37.

发明专利
COMPUESTOS DE PURINONA COMO INHIBIDORES DE QUINASAS. 未知

公开(公告)号：MX2014009219A

公开(公告)日：2015-02-05

申请号：MX2014009219

申请日：2013-01-30

Applicant: PHARMACYCLICS INC

Inventor： YAN SHUNQI , CHEN WEI , LOURY DAVID J , WANG LONGCHENG , FRYE LEAH LYNN

IPC: C07D473/32 , A61K31/52 , A61P35/00 , A61P37/00

Abstract: Se describen en el presente documento compuestos que forman enlaces covalentes con la tirosina quinasa de Bruton (Btk). También se describen inhibidores irreversibles de Btk. Además, también se describen inhibidores reversibles de Btk. También se describen composiciones farmacéuticas que incluyen los compuestos. Se describen métodos para utilizar los inhibidores de Bkt, solos junto con otros agentes terapéuticos, para el tratamiento de dolencias o enfermedades autoinmunes, enfermedades o dolencias heteroinmunes, cáncer, incluyendo linfoma, y enfermedades o dolencias inflamatorias.

38.

发明专利
Inhibitors of Bruton's tyrosine kinase 未知

公开(公告)号：AU2012283775A8

公开(公告)日：2014-02-20

申请号：AU2012283775

申请日：2012-07-13

Applicant: PHARMACYCLICS INC , WANG LONGCHENG

Inventor： CHEN WEI , LOURY DAVID J , MODY TARAK D , WANG LONGCHENG

IPC: C07D473/32 , A61K31/433 , A61K31/52 , A61P17/00 , A61P29/00 , C07D473/34

Abstract: Described herein are kinase inhibitor compounds, methods for synthesizing such inhibitors, and methods for using such inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate inhibitor of a protein, including a kinase.

39.

发明专利
INHIBITORS OF BRUTON'S TYROSINE KINASE 未知

公开(公告)号：ZA201202552B

公开(公告)日：2013-11-27

申请号：ZA201202552

申请日：2012-04-10

Applicant: PHARMACYCLICS INC

Inventor： LUO WENCHEN , SMYTH MARK STEPHEN , MODY TARAK D , LOURY DAVID J , VERNER ERIK , CHEN WEI

40.

发明专利
PURINONE COMPOUNDS AS KINASE INHIBITORS 未知

公开(公告)号：CA2863140A1

公开(公告)日：2013-08-08

申请号：CA2863140

申请日：2013-01-30

Applicant: PHARMACYCLICS INC

Inventor： YAN SHUNQI , WANG LONGCHENG , FRYE LEAH LYNN , CHEN WEI , LOURY DAVID J

IPC: C07D473/32 , A61K31/52 , A61P35/00 , A61P37/00

Abstract: Disclosed herein are compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. In addition, reversible inhibitors of Btk are also described. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.

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