公开(公告)号：NO20064519A

公开(公告)日：2006-12-15

申请号：NO20064519

申请日：2006-10-05

Applicant: PTC THERAPEUTICS INC

Inventor： HWANG SEONGWOO ,  MOON YOUNG-CHOON ,  CAO LIANGXIAN ,  TAMILARASU NADARAJAN ,  QL HONGYAN ,  CHOI SOONGYU ,  LENNOX WILLIAM JOSEPH ,  CORSON DONALD THOMAS

IPC: A61K31/437 ,  A61K31/4745 ,  A61K31/497 ,  A61K31/506 ,  A61K31/5355 ,  A61K31/541 ,  A61K31/551 ,  A61K31/724 ,  A61P35/00 ,  C07D471/04

CPC classification number: A61K31/506 ,  A61K31/437 ,  A61K31/4745 ,  A61K31/497 ,  A61K31/5355 ,  A61K31/541 ,  A61K31/551 ,  C07D471/04

公开(公告)号：BRPI0409319A

公开(公告)日：2006-04-25

申请号：BRPI0409319

申请日：2004-04-09

Applicant: PTC THERAPEUTICS INC

Inventor： KARP GARY MITCHELL ,  HWANG SEONGWOO ,  CHEN GUANGMING ,  ALMSTEAD NEIL GREGORY

IPC: A61K31/4245 ,  C07D271/06 ,  C07D271/12 ,  C07D413/04 ,  C07D413/10

Abstract: Provided herein is a compound of formulaor a pharmaceutically acceptable salt thereof for use in a method for treating a lysosomal storage disorder associated with a premature stop codon in a patient.

公开(公告)号：CA2521992A1

公开(公告)日：2004-10-28

申请号：CA2521992

申请日：2004-04-09

Applicant: PTC THERAPEUTICS INC

Inventor： MOON YOUNG-CHOON ,  HWANG SEONGWOO ,  KARP GARY MITCHELL ,  ALMSTEAD NEIL GREGORY ,  CHEN GUANGMING

IPC: A61K31/4245 ,  C07D271/06 ,  C07D271/12 ,  C07D413/04 ,  C07D413/10

Abstract: Novel 1,2,4-oxadiazole benzoic acid compounds, methods of using and pharmaceutical compositions comprising an 1,2,4-oxadiazole benzoic acid derivative are disclosed. The methods include methods of treating or preventing a disease ameliorated by modulation of premature translation termination or nonsense-mediated mRNA decay, or ameliorating one or more symptoms associated therewith.

公开(公告)号：AU2003256755A1

公开(公告)日：2004-02-09

申请号：AU2003256755

申请日：2003-07-23

Applicant: PTC THERAPEUTICS INC

Inventor： WILDE RICHARD G ,  TAKASUGI JAMES J ,  HWANG SEONGWOO ,  WELCH ELLEN M ,  CHEN GUANGMING

IPC: A61K31/17 ,  A61K31/4166 ,  A61P35/00 ,  C07C275/42 ,  C07D233/32 ,  C07D233/42 ,  C07D233/70 ,  C07D233/72 ,  C07D233/78 ,  C07D233/84 ,  C07D285/16 ,  C07D401/04 ,  C07D401/10 ,  C07D405/04 ,  C07D405/06 ,  C07D409/04 ,  C07D233/00

Abstract: The invention encompasses ureido substituted benzoic acid compounds, compositions comprising the compounds and methods for treating or preventing diseases associated with nonsense mutations of mRNA by administering these compounds or compositions.

公开(公告)号：DK3889142T3

公开(公告)日：2022-09-12

申请号：DK21169137

申请日：2004-04-09

Applicant: PTC THERAPEUTICS INC

Inventor： KARP GARY MITCHELL ,  HWANG SEONGWOO ,  CHEN GUANGMING ,  ALMSTEAD NEIL G ,  MOON YOUNG-CHOON

IPC: A61K31/4245 ,  C07D271/06 ,  A61P35/00 ,  C07D271/12 ,  C07D413/04 ,  C07D413/10

公开(公告)号：SI3632902T1

公开(公告)日：2022-01-31

申请号：SI200432514

申请日：2004-04-09

Applicant: PTC THERAPEUTICS INC

Inventor： KARP GARY MITCHELL ,  HWANG SEONGWOO ,  CHEN GUANGMING ,  ALMSTEAD NEIL GREGORY ,  MOON YOUNG-CHOON

IPC: C07D271/00 ,  A61K31/00 ,  A61K31/4245 ,  A61P35/00 ,  C07D271/06 ,  C07D271/12 ,  C07D413/04 ,  C07D413/10

公开(公告)号：HUE055031T2

公开(公告)日：2021-10-28

申请号：HUE16874024

申请日：2016-12-11

Applicant: PTC THERAPEUTICS INC

Inventor： BABU SURESH ,  BHATTACHARYYA ANURADHA ,  HWANG SEONGWOO ,  JANI MINAKSHI ,  MOON YOUNG-CHOON ,  SYDORENKO NADIYA

IPC: C07D403/12 ,  C07D237/20 ,  C07D401/14 ,  C07D403/10 ,  C07D405/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14 ,  C07D471/10 ,  C07D487/10

公开(公告)号：DK3632902T3

公开(公告)日：2021-09-13

申请号：DK19209758

申请日：2004-04-09

Applicant: PTC THERAPEUTICS INC

Inventor： KARP GARY MITCHELL ,  HWANG SEONGWOO ,  CHEN GUANGMING ,  ALMSTEAD NEIL GREGORY ,  MOON YOUNG-CHOON

IPC: C07D271/06 ,  A61K31/4245 ,  A61P35/00 ,  C07D271/12 ,  C07D413/04 ,  C07D413/10

公开(公告)号：DK3386511T3

公开(公告)日：2021-07-05

申请号：DK16874024

申请日：2016-12-11

Applicant: PTC THERAPEUTICS INC

Inventor： BABU SURESH ,  BHATTACHARYYA ANURADHA ,  HWANG SEONGWOO ,  JANI MINAKSHI ,  MOON YOUNG-CHOON ,  SYDORENKO NADIYA

IPC: C07D403/12 ,  A61K31/501 ,  A61K31/506 ,  A61K31/517 ,  C07D237/20 ,  C07D401/14 ,  C07D403/10 ,  C07D405/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14 ,  C07D471/10 ,  C07D487/10

公开(公告)号：NZ743147A

公开(公告)日：2021-03-26

申请号：NZ74314716

申请日：2016-12-11

Applicant: PTC THERAPEUTICS INC

Inventor： MOON YOUNG-CHOON ,  BABU SURESH ,  BHATTACHARYYA ANURADHA ,  HWANG SEONGWOO ,  JANI MINAKSHI ,  SYDORENKO NADIYA

IPC: A61K31/506 ,  A61P25/00 ,  C07D405/12

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington’s disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (Ia), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington’s disease.