公开(公告)号：WO02082604A3

公开(公告)日：2002-12-05

申请号：PCT/NL0200223

申请日：2002-04-05

Applicant: STICHTING TECH WETENSCHAPP ,  OFFERHAUS HERMAN LEONARD

Inventor： OFFERHAUS HERMAN LEONARD

IPC: G02B5/32 ,  H01S5/00 ,  H01S5/14 ,  H01S5/40

CPC classification number: G02B27/0944 ,  G02B5/32 ,  G03H1/0248 ,  G03H1/0402 ,  G03H2001/0434 ,  H01S5/005 ,  H01S5/145 ,  H01S5/4012 ,  H01S5/4025 ,  H01S5/4062

Abstract: The invention relates to an apparatus for generating a coherent laser beam from an emission of a series of diode lasers, comprising at least one row of source diodes and a system for transforming the primary light emission emitted by the source diodes into secondary coherent light emission, wherein the system for transforming the primary emission into secondary coherent light emission includes a hologram, which comprises an image of an interference pattern of the primary light emission and the secondary coherent light emission, so that when illuminating the hologram with the primary light emission, the hologram reflects the secondary coherent light emission, and in that a mirror is provided in the path of the secondary coherent light emission, which reflects at least some of the secondary coherent light emission vie the hologram to the diode lasers.

Abstract translation: 本发明涉及一种用于从一系列二极管激光器的发射产生相干激光束的设备，该设备包括至少一行源二极管和用于将源二极管发射的初级光发射转换为二次相干光发射的系统， 其中用于将所述主发射变换为次级相干发光的所述系统包括全息图，所述全息图包括所述初级发光和所述次级相干发光的干涉图案的图像，使得当用所述初级发光照射所述全息图时，所述 全息图反映次级相干光发射，并且在次级相干光发射的路径中提供反射镜，该反射镜将全息图中的至少一些次级相干光发射反射至二极管激光器。

公开(公告)号：WO0160944A3

公开(公告)日：2002-02-14

申请号：PCT/EP0101837

申请日：2001-02-16

Applicant: STICHTING TECH WETENSCHAPP ,  DORENBOS PIETER ,  EIJK CAREL WILHELM EDUARD VAN ,  GUEDEL HANS ULRICH ,  KRAEMER KARL WILHELM ,  LOEF EDGAR VALENTIJN DIEUWER V

Inventor： DORENBOS PIETER ,  VAN EIJK CAREL WILHELM EDUARD ,  GUEDEL HANS-ULRICH ,  KRAEMER KARL WILHELM ,  VAN LOEF EDGAR VALENTIJN DIEUW

IPC: G01T1/20 ,  C01F17/00 ,  C09K11/00 ,  C09K11/08 ,  C09K11/77 ,  C09K11/85 ,  C30B29/12 ,  G01T1/202

CPC classification number: G01T1/2023 ,  C01F17/0056 ,  C01F17/0068 ,  C09K11/7772

Abstract: The invention concerns an inorganic scintillator material of general composition M1-xCexCl3, wherein: M is selected among lanthanides or lanthanide mixtures, preferably among the elements or mixtures of elements of the group consisting of Y, La, Gd, Lu, in particular among the elements or mixtures of elements of the group consisting of La, Gd and Lu; and x is the molar rate of substitution of M with cerium, x being not less than 1 mol %and strictly less than 100 mol %. The invention also concerns a method for growing said monocrystalline scintillator material, and the use of said scintillator material as component of a scintillating detector in particular for industrial and medical purposes and in the oil industry.

Abstract translation: 本发明涉及一般组合物M1-xCexCl3的无机闪烁体材料，其中：M选自镧系元素或镧系元素混合物，优选选自Y，La，Gd，Lu中的元素或元素混合物，特别是在 由La，Gd和Lu组成的组分元素或元素的混合物; x是M与铈的摩尔摩尔比，x不小于1摩尔％，严格小于100摩尔％。 本发明还涉及用于生长所述单晶闪烁体材料的方法，以及使用所述闪烁体材料作为闪烁检测器的组分，特别用于工业和医疗目的以及在石油工业中。

公开(公告)号：WO0006198A3

公开(公告)日：2001-07-19

申请号：PCT/NL9900478

申请日：1999-07-26

Applicant: ID LELYSTAD ,  STICHTING TECH WETENSCHAPP ,  TNO ,  VRIJE UNIVERSITEIT AMSTERDAM ,  IWAARDEN JOHAN FREDERIK VAN ,  KRAAL GEORG ,  JEURISSEN SUSSANNE HENRIETTE M

Inventor： VAN IWAARDEN JOHAN FREDERIK ,  KRAAL GEORG ,  JEURISSEN SUSSANNE HENRIETTE M

IPC: A61K39/39 ,  A61P37/04

CPC classification number: A61K39/39 ,  A61K2039/55516 ,  A61K2039/55555

Abstract: The invention relates to the field of immunology, more specifically to adjuvants used to increase the immunogenicity of antigens, e.g. for incorporation in vaccines. The invention provides use of a pulmonary surfactant or a component thereof as adjuvant substances that are able to stimulate an immune response but that in general are homologous to substances native to the body.

Abstract translation: 本发明涉及免疫学领域，更具体地涉及用于增加抗原免疫原性的佐剂，例如， 用于疫苗注册。 本发明提供了肺表面活性剂或其组分作为能够刺激免疫应答但是通常与身体天然物质同源的辅助物质的用途。

公开(公告)号：WO9937678A3

公开(公告)日：1999-10-14

申请号：PCT/NL9900045

申请日：1999-01-26

Applicant: STICHTING TECH WETENSCHAPP ,  NIEUW AMERONGEN ARIE VAN ,  VEERMAN ENGELMUNDUS CORNELIS I ,  T HOF WILLEM VAN ,  HELMERHORST EVA JOSEPHINE

Inventor： VAN NIEUW AMERONGEN ARIE ,  VEERMAN ENGELMUNDUS CORNELIS I ,  VAN T HOF WILLEM ,  HELMERHORST EVA JOSEPHINE

IPC: A61K9/06 ,  A61K9/12 ,  A61K38/00 ,  A61P31/04 ,  A61P31/10 ,  C07K7/08 ,  C07K14/47 ,  A61K38/10 ,  A61K38/17

CPC classification number: C07K7/08 ,  A61K38/00 ,  C07K14/4723

Abstract: The invention relates to peptides with antimicrobial activity, consisting of an amino acid chain which contains a domain of 10 to 25 amino acids, wherein the majority of the amino acids of the one half of the domain are positively charged amino acids and the majority of the amino acids of the other half of the domain are uncharged amino acids.

Abstract translation: 本发明涉及具有抗微生物活性的肽，其由含有10至25个氨基酸的结构域的氨基酸链组成，其中结构域的一半的大部分氨基酸为带正电荷的氨基酸，并且大部分 另一半结构域的氨基酸是不带电荷的氨基酸。

公开(公告)号：WO2011159153A3

公开(公告)日：2012-02-16

申请号：PCT/NL2011050428

申请日：2011-06-14

Applicant: UNIV UTRECHT HOLDING BV ,  STICHTING TECH WETENSCHAPP ,  OHM ROBIN ARTHUR ,  LUGONES LUIS GASTON ,  WOESTEN HERMAN ABEL BERNARD

Inventor： OHM ROBIN ARTHUR ,  LUGONES LUIS GASTON ,  WOESTEN HERMAN ABEL BERNARD

IPC: C07K14/37 ,  C12N15/80

CPC classification number: C12N15/80 ,  C07K14/37 ,  C12N1/14 ,  C12P21/02

Abstract: The invention relates to a method of producing mushroom using a heat inducible promoter. The invention further relates to a heat inducible promoter, a nucleic acid construct, a vector and a fungus or mushroom comprising a heat inducible promoter of the invention and to methods for producing such a mushroom or fungus or a substance of interest.

Abstract translation: 本发明涉及使用热诱导型启动子生产蘑菇的方法。 本发明还涉及包含本发明的热诱导型启动子的热诱导型启动子，核酸构建体，载体和真菌或蘑菇以及用于产生这种蘑菇或真菌或感兴趣的物质的方法。

公开(公告)号：WO2011059329A3

公开(公告)日：2011-09-01

申请号：PCT/NL2010050755

申请日：2010-11-12

Applicant: UNIV UTRECHT HOLDING BV ,  VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG ,  STICHTING TECH WETENSCHAPP ,  UNIV LEIDEN ,  VANKUYK PATRICIA ANN ,  DE VRIES RONALD PETER ,  VISSER JACOB ,  RAM ARTHUR FRANCISCUS JOHANNES ,  VAN DEN HONDEL CORNELIS ANTONIUS MARIA JACOBUS JOH ,  BATTAGLIA EVY ,  VIVAS DUARTE DIANA ALEXANDRA

Inventor： VANKUYK PATRICIA ANN ,  DE VRIES RONALD PETER ,  VISSER JACOB ,  RAM ARTHUR FRANCISCUS JOHANNES ,  VAN DEN HONDEL CORNELIS ANTONIUS MARIA JACOBUS JOH ,  BATTAGLIA EVY ,  VIVAS DUARTE DIANA ALEXANDRA

IPC: C07K14/38

CPC classification number: C07K14/38 ,  Y02E50/16

Abstract: The invention relates to the production of biofuels, proteins, peptides and other value-added compounds from crude carbon sources. The inventors identified genes encoding novel pentose transporters, in particular transporters of L-arabinose and/or D-xylose. Regulation of the Aspergillus niger genes by xlnR and araR was instrumental in the identification of these genes and their substrate specificities. Provided are novel pentose transporters and their encoding nucleic acids. Also provided are host cells (over)expressing a transporter, and industrial applications thereof, for instance in biofuel production.

Abstract translation: 本发明涉及从粗碳源生产生物燃料，蛋白质，肽和其他增值化合物。 发明人确定了编码新戊糖转运蛋白的基因，特别是L-阿拉伯糖和/或D-木糖的转运蛋白。 通过xlnR和araR调节黑曲霉基因有助于鉴定这些基因及其底物特异性。 提供新的戊糖转运蛋白及其编码核酸。 还提供了表达转运蛋白的宿主细胞（以上）及其工业应用，例如在生物燃料生产中。

公开(公告)号：WO2010124344A9

公开(公告)日：2011-02-03

申请号：PCT/AU2010000504

申请日：2010-04-30

Applicant: INT FLOWER DEV PTY LTD ,  STICHTING TECH WETENSCHAPP ,  VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG ,  QUATTROCCHIO FRANCESCA ,  KOES RONALD ,  SPELT KEES

Inventor： QUATTROCCHIO FRANCESCA ,  KOES RONALD ,  SPELT KEES

IPC: C12N15/05 ,  A01H1/00 ,  A01H5/00

CPC classification number: C12N15/825 ,  A01H5/02 ,  A01H5/08 ,  C07K14/415 ,  C12N9/14 ,  C12N15/8243 ,  C12N15/8249 ,  C12N15/827

Abstract: The present invention relates generally to the field of plant molecular biology and agents useful in the manipulation of plant physiological and biochemical properties. More particularly, the present invention provides genetic and proteinaceous agents capable of modulating or altering the level of acidity or alkalinity in a cell, group of cells, organelle, part or reproductive portion of a plant. Genetically altered plants, plant parts, progeny, subsequent generations and reproductive material including flowers or flowering parts having cells exhibiting an altered cellular including vacuolar pH compared to a non-genetically altered plant are also provided.

Abstract translation: 本发明一般涉及植物分子生物学领域和用于操作植物生理和生物化学性质的试剂。 更具体地，本发明提供能够调节或改变细胞，细胞组，细胞器，植物的部分或繁殖部分中的酸度或碱度水平的遗传和蛋白质试剂。 还提供了遗传改变的植物，植物部分，子代，后代和包括花或开花部分的繁殖材料，其具有与非遗传改变植物相比显示具有改变的细胞的细胞，包括液泡pH。

公开(公告)号：WO2008075961A3

公开(公告)日：2008-12-18

申请号：PCT/NL2007050698

申请日：2007-12-21

Applicant: UNIV TWENTE ,  STICHTING TECH WETENSCHAPP ,  MANOHAR SRIRANG ,  VAN LEEUWEN ANTONIUS GERARDUS JOHANNES MARIA

Inventor： MANOHAR SRIRANG ,  VAN LEEUWEN ANTONIUS GERARDUS JOHANNES MARIA

IPC: A61B8/08

CPC classification number: A61B8/08 ,  A61B5/0095 ,  A61B8/4281 ,  G01N29/0672 ,  G01N29/228 ,  G01N29/2418 ,  G01N2291/011 ,  G01N2291/015 ,  G01N2291/0237

Abstract: A thermoacoustic imaging apparatus comprises an electromagnetic radiation source configured to irradiate a sample area and an acoustic signal detection probe arrangement for detecting acoustic signals. A radiation responsive acoustic signal generator is added outside the sample area. The detection probe arrangement detects both signals generated in a sample area in response to the irradiation and an acoustic signal from the radiation responsive acoustic signal generator that has travelled through the sample area. A computing system distinguishes first acoustic signal detections attributed to the acoustic signal generated by the radiation responsive acoustic signal generator and second acoustic signal detections attributed to the acoustic signals generated by the sample area. The computing system performs a tomographic computation of an acoustic transmission parameter as a function of a position in the sample area from the first acoustic signal detections. The acoustic transmission parameter may be a speed of sound or absorption. The acoustic transmission parameter may be used to correct the computation of a thermoacoustic image.

Abstract translation: 热声成像装置包括被配置为照射样本区域的电磁辐射源和用于检测声信号的声信号检测探头装置。 辐射响应声信号发生器被添加到样本区域外部。 检测探针装置响应于照射而检测在样本区域中产生的信号和来自已经穿过样本区域的辐射响应声信号发生器的声信号。 计算系统区分归因于由辐射响应声信号发生器产生的声信号的第一声信号检测和归因于由样本区产生的声信号的第二声信号检测。 计算系统根据第一声信号检测，根据样本区域中的位置进行声传输参数的断层计算。 声学传播参数可以是声音或吸收的速度。 声传播参数可用于校正热声图像的计算。

公开(公告)号：WO2008075955A3

公开(公告)日：2008-09-12

申请号：PCT/NL2007050676

申请日：2007-12-20

Applicant: STICHTING TECH WETENSCHAPP ,  STICHTING KATHOLIEKE UNIV ,  RUTJES FLORIS PETRUS JOHANNES ,  CORNELISSEN JEROEN JOHANNES LA ,  VAN BERKEL SANDER SEBASTIAAN ,  DIRKS ANTONIUS JOHANNES

Inventor： RUTJES FLORIS PETRUS JOHANNES ,  CORNELISSEN JEROEN JOHANNES L ,  VAN BERKEL SANDER SEBASTIAAN ,  DIRKS ANTONIUS JOHANNES

IPC: C07D249/04 ,  C07D487/08 ,  C07D493/08

CPC classification number: C07D249/04 ,  C07D487/08 ,  C07D493/08

Abstract: The present invention relates to a process for the preparation of 1,4,5- trisubstituted triazoles and 3,4,5-trisubstituted triazoles according to Formulas (Ia) and 5 (Ib), and mesomers and tautomers thereof, wherein a compound according to Formula (II) or Formula (III): is reacted with a compound according to Formula (IV). The process is very useful for the selective and site-specific addition of azide compounds to optionally activated alkynes to form 1,4,5-trisubstuted triazoles and mesomers and tautomers thereof and the application of this process to the covalent functionalisation of biomolecules.

Abstract translation: 本发明涉及制备根据式（Ia）和5（Ib）的1,4,5-三取代三唑和3,4,5-三取代三唑及其互变异构体和互变异构体的方法， 与式（II）或式（III）反应：与式（IV）化合物反应。 该方法对于将选择性和位点特异性加成任选活化的炔烃以形成1,4,5-三分子三唑及其互变异构体和互变异构体以及将该方法应用于生物分子的共价官能化是非常有用的。

公开(公告)号：WO2008010704A3

公开(公告)日：2008-08-21

申请号：PCT/NL2007000183

申请日：2007-07-17

Applicant: STICHTING TECH WETENSCHAPP ,  UNIV EINDHOVEN TECH ,  HECK MARTIJN JAN RESIE ,  BENTE ERWIN ANTONIUS JOSEPH MA

Inventor： HECK MARTIJN JAN RESIE ,  BENTE ERWIN ANTONIUS JOSEPH MA

IPC: H01S5/50 ,  H01S5/06 ,  H01S5/40

CPC classification number: H01S5/50 ,  H01S5/0057 ,  H01S5/0602 ,  H01S5/4025 ,  H01S5/5027

Abstract: The present invention relates to a semiconductor optical element for processing at least one optical pulse, comprising an optical path for propagating the optical pulse through the optical element from an input to an output, one or more pairs of optical processing units being situated in the optical path, wherein each pair of optical processing units comprises at least one saturable optical amplifier and at least one saturable optical absorption unit, the absorption element being arranged for entering into saturation when a pulse energy received by the absorption element is higher than a saturation energy of the absorption element, and the amplifier elements being arranged for entering into saturation when a pulse energy received by the amplifier element is higher than a saturation energy of the amplifier element, whilst it holds for each pair of processing units that the saturation energy of the absorption element is lower than the saturation energy of the amplifier element.

Abstract translation: 本发明涉及一种用于处理至少一个光脉冲的半导体光学元件，包括用于通过光学元件从输入到输出传播光脉冲的光路，一对或多对光学处理单元位于光学 路径，其中每对光学处理单元包括至少一个饱和光学放大器和至少一个可饱和光学吸收单元，所述吸收元件布置成当由所述吸收元件接收的脉冲能量高于饱和能量时 吸收元件和放大器元件被布置成当放大器元件接收的脉冲能量高于放大器元件的饱和能量时进入饱和，而对于每对处理单元来说，吸收元件的吸收元件的吸收饱和能量 元件低于放大器元件的饱和能量。