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公开(公告)号：KR1020140069899A
公开(公告)日：2014-06-10
申请号：KR1020120137748
申请日：2012-11-30
Applicant: (주)아모레퍼시픽
Abstract: The present invention relates to a composition containing deep ocean water for skin moisturizing and, more specifically, to a composition containing deep ocean water for skin moisturizing which comprises manganese, calcium, and potassium in a content ratio (w/v) of 2-4: 0.5-1.5: 0.5-1.5.
Abstract translation: 本发明涉及含有用于皮肤保湿的深海水的组合物，更具体地说，涉及包含含有比例（w / v）为2-4的锰，钙和钾的皮肤保湿深层海水的组合物 ：0.5-1.5：0.5-1.5。
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公开(公告)号：KR101219294B1
公开(公告)日：2013-01-08
申请号：KR1020060071985
申请日：2006-07-31
Applicant: (주)아모레퍼시픽
Abstract: 본발명은α-케토글루타레이트(α-ketoglutarate)를함유하는주름개선용화장료조성물에관한것으로, 보다상세하게는α-케토글루타레이트가콜라겐의주요구성아미노산인프롤린의공급에관여하는프롤리다아제활성을증가시킴으로써콜라겐생성을촉진시키는주름개선용화장료조성물에관한것이다. 또한, 본발명에의한화장료조성물은상기α-케토글루타레이트와함께α-리포익산(α-lipoic acid)을유효성분으로더 함유할수 있으며, 상기α-리포익산은프롤릴-4-수산화효소발현을증가시켜생성된프로콜라겐이올바른삼중나선(triple helix)을형성시키는역할을한다. 즉, 본발명에의한화장료조성물은프롤리다아제활성을증가시키는α-케토글루타레이트와함께α-리포익산을함유함으로써콜라겐생합성을촉진시킨다.
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公开(公告)号：KR101151049B1
公开(公告)日：2012-06-01
申请号：KR1020050057462
申请日：2005-06-30
Applicant: (주)아모레퍼시픽
Abstract: 본발명은피부외용제조성물에관한것으로서, 보다상세하게는 5개의아미노산연쇄분자에팔미토일기를결합한팔미토일펜타펩타이드, 대두배아이소플라본어글리콘, 자주개자리추출물및 붓꽃추출물을조합하여만든혼합물을이용하여피부주름의개선, 피부탄력증진또는피부보습증진에효과가우수한외용제조성물에관한것이다.
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44.发明公开Ｋｌｏｔｈｏ 유전자를 포함하는 피부 활성물질 탐색용 키트 및 이를 이용하여 피부 활성물질을 탐색하는 방법 审中-实审包含KLOTHO基因的皮肤活性成分的检测工具和使用其检测皮肤活性成分的方法
公开(公告)号：KR1020120049126A
公开(公告)日：2012-05-16
申请号：KR1020110107409
申请日：2011-10-20
Applicant: (주)아모레퍼시픽
CPC classification number: G01N33/5044 , C12Q1/6876 , C12Q1/6883 , C12Q2600/148 , C12Q2600/158 , G01N33/5023 , G01N33/6881 , G01N33/5302
Abstract: PURPOSE: A kit for detecting a skin active material and a detection method using the same are provided to quickly and simply screen antioxidative, whitening and moisturizing materials. CONSTITUTION: A kit for detecting a skin active material contains Klotho protein gene, primer for amplifying the gene of sequence numbers 1 and 2, a probe of sequence number 3, and a material which enhances Klotho protein expression level in skin cells. The skin active material is a material for moisturizing, anti-aging, or whitening. The skin cells are human keratinocytes, fibroblast, or melanocytes.
Abstract translation: 目的：提供用于检测皮肤活性物质的试剂盒和使用其的检测方法，以快速且简单地筛选抗氧化，美白和保湿材料。 构成：用于检测皮肤活性物质的试剂盒含有Klotho蛋白质基因，用于扩增序列号1和2的基因的引物，序列号3的探针和增强皮肤细胞中Klotho蛋白表达水平的材料。 皮肤活性物质是保湿，抗衰老或美白的材料。 皮肤细胞是人角质形成细胞，成纤维细胞或黑素细胞。
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公开(公告)号：KR1020110056820A
公开(公告)日：2011-05-31
申请号：KR1020090113295
申请日：2009-11-23
Applicant: (주)아모레퍼시픽
CPC classification number: A61Q17/04 , A61K8/37 , A61K8/4946
Abstract: PURPOSE: A composition containing octyl salicylate or phenylbenaimidazole sulfonic acid is provided to effectively block UVC and UVB. CONSTITUTION: A composition for blocking UVC contains one or more selected from the group consisting of octyl salicylate or phenylbenzimidazole sulfonic acid as an active ingredient. The composition is used in the form of solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing, oil, foundation, oil-in-water, or water-in-oil. The maximum absorbance is in the wavelength of 200-290 nm.
Abstract translation: 目的：提供含有辛基水杨酸酯或苯乙咪唑磺酸的组合物，以有效阻断UVC和UVB。 构成：用于封闭UVC的组合物含有选自水杨酸辛酯或苯基苯并咪唑磺酸作为活性成分的一种或多种。 该组合物以溶液，悬浮液，乳液，糊剂，凝胶，霜剂，洗剂，粉末，肥皂，含表面活性剂的清洁剂，油，粉底液，水包油或油包水的形式使用。 最大吸光度为200-290nm波长。
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Patent Agency Ranking
公开(公告)号：KR1020100000391A
公开(公告)日：2010-01-06
申请号：KR1020080059872
申请日：2008-06-24
Applicant: (주)아모레퍼시픽 , 서울대학교산학협력단
Abstract: PURPOSE: A method for screening a cosmetic material and cosmetic composition containing a material suppressing TRPV-1(transient receptor potential family V-1) are provided to select a target material which is effective in anti-aging and reduce skin irritation. CONSTITUTION: A material which suppresses activation of TRPV-1(transient receptor potential family V-1) contains extract isolated from one or more selected from Prunus mume Sieb. et Zucc., Pleuropterus multflorus, and Atractylodes japonica Koidxumi or Atractylodes ovate Koidzumi. A cosmetic composition contains 0.001-10 weight%, preferably 0.01-5 weight% of the extract. The cosmetic composition is used in the form of nutrition skin, massage cream, pack gel or lotion, ointment, cream, patch or spray.
Abstract translation: 目的：提供一种筛选含有抑制TRPV-1（瞬时受体潜能家族V-1）的物质的美容材料和化妆品组合物的方法，以选择有效抗衰老和降低皮肤刺激性的目标材料。 构成：抑制TRPV-1（瞬时受体电位家族V-1）活化的物质含有从一种或多种选自杏仁酵母中分离的提取物。 等等，Pleuropterus multflorus和Atractylodes japonica Koidxumi或Atractylodes ovate Koidzumi。 化妆品组合物含有0.001-10重量％，优选0.01-5重量％的提取物。 化妆品组合物以营养皮肤，按摩膏，包装凝胶或洗剂，软膏，霜剂，贴剂或喷雾剂的形式使用。
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公开(公告)号：KR100926225B1
公开(公告)日：2009-11-09
申请号：KR1020070123407
申请日：2007-11-30
Applicant: (주)아모레퍼시픽 , 재단법인서울대학교산학협력재단
Abstract: 카베올린의 생성량 조절을 통해 항노화, 피부 탄력 강화, 및 주름 예방 또는 개선의 효능을 달성하는 조성물과 카베올린 생성량 증가를 통해 항노화, 피부 탄력 강화, 및 주름 예방 또는 개선의 효능을 갖는 피부 유용 물질을 스크리닝하는 방법이 개시된다.
카베올린, 콜라겐, 콜레스테롤, 매트릭스메탈로프로티아제, 주름 개선, 항노화, 탄력-
公开(公告)号：KR1020080049174A
公开(公告)日：2008-06-04
申请号：KR1020060119447
申请日：2006-11-30
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/498 , A61K8/04 , A61K8/97 , A61K31/352 , A61K36/752 , A61Q19/08
Abstract: A method for preparing diosmetin is provided to obtain the diosmetin which promotes biosynthesis of a type I pro-collagen by decreasing biosynthesis of MMP-1 caused by UV. A cosmetic composition comprising the diosmetin is provided to show excellent skin anti-aging and wrinkle improving effects. A method for preparing diosmetin comprises the steps of: (a) obtaining a lemon peel extract using an organic solvent; (b) preparing a hydrolysate from the extract using an acid, a base or an enzyme; and (c) purifying the hydrolysate using silica gel column chromatography. A cosmetic composition comprises 0.0001-5 wt.% of the diosmetin as an effective ingredient. Further, the cosmetic composition is in a form of cosmetic water, cream, essence, eye cream, eye essence, cleansing cream, cleansing form, cleansing water, pack, powder, body lotion, body cream, body oil or body essence.
Abstract translation: 提供一种制备二硫代甜氨酸的方法，以通过降低由UV引起的MMP-1的生物合成来获得促进I型前胶原生物合成的diosmetin。 提供了含有二硫代甜氨酸的化妆品组合物，以显示优异的皮肤抗衰老和皱纹改善效果。 一种制备diosmetin的方法包括以下步骤：（a）使用有机溶剂获得柠檬皮提取物; （b）使用酸，碱或酶从提取物制备水解产物; 和（c）使用硅胶柱色谱纯化水解产物。 化妆品组合物包含0.0001-5重量％的二硫代甜胺作为有效成分。 此外，化妆品组合物是化妆水，奶油，精华，眼霜，眼睛精华，清洁霜，清洁剂，清洁水，包装，粉末，身体乳液，身体霜，身体油或身体精华的形式。
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公开(公告)号：KR1020080020973A
公开(公告)日：2008-03-06
申请号：KR1020070089158
申请日：2007-09-03
Applicant: (주)아모레퍼시픽
CPC classification number: A61Q19/08 , A61K8/11 , A61K8/14 , A61K8/361 , A61K8/922 , A61K36/185 , A61K2800/412
Abstract: An external skin composition containing omega-3 fatty acids is provided to restore damaged skin barrier, protect the skin from outside harmful environments, moisturize the skin, increase skin permeability of useful ingredients, and improve stability of omega-3 fatty acids. An external skin composition for improving skin health contains 0.5-3 wt.% of omega-3 fatty acids in a type of omega-3 fatty acid-containing oil such as black current oil, and is formulated as oil-in-water type emulsion having an oil droplet with omega-3 fatty acid and a water phase with lipid nanoparticles having no omega-3 fatty acid, wherein the omega-3 fatty acid is solubilized in ether oil phase or lipid nanoparticles in water phase of the oil-in-water type emulsion. Further, the external skin composition prevents or treats wrinkle of the skin.
Abstract translation: 提供含有ω-3脂肪酸的外用皮肤组合物以恢复受损的皮肤屏障，保护皮肤免受外界有害环境的影响，滋润皮肤，增加皮肤对有用成分的渗透性，并提高ω-3脂肪酸的稳定性。 用于改善皮肤健康的外用皮肤组合物含有0.5-3重量％的ω-3脂肪酸类的一种ω-3脂肪酸的油如黑色电流油，并且被配制成水包油型乳液 具有ω-3脂肪酸的油滴和具有不含ω-3脂肪酸的脂质纳米颗粒的水相，其中ω-3脂肪酸溶解于油相中的醚油相或脂质纳米颗粒中， 水型乳液。 此外，外用皮肤组合物可防止或治疗皮肤的皱纹。
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公开(公告)号：KR1020050022251A
公开(公告)日：2005-03-07
申请号：KR1020040020401
申请日：2004-03-25
Applicant: (주)아모레퍼시픽
IPC: C07C239/14
Abstract: PURPOSE: Provided are a hydroxamic acid derivative which shows an antiaging effect and is improved in safety and stability to the skin stimulus and discoloration, its preparation method, and an antiaging skin preparation for external use and a collagenase and elastase expression inhibitor containing the derivative. CONSTITUTION: The hydroxamic acid derivative is represented by the formula 1, wherein R1 and R2 are H, a C1-C10 alkyl group or a C3-C6 cycloalkyl group; R3 is CONH, NHCO, CONR5 or NR5CO (wherein R5 is H or a C1-C10 alkyl group); and R4 is -(CH)n- (wherein n is 0 or 1). The method comprises the steps of reacting benzoic acid and methyl 4-aminobenzoate or 4-aminophenylacetic acid methyl ester or reacting aniline and monomethyl terephthalate, to prepare a benzamide compound; substituting the amino bond of the benzamide compound into an alkyl bond; hydrolyzing the methyl ester group to prepare an acid; and reacting the obtained acid with hydroxyl amine·HCl salt to prepare the hydroxamic acid derivative of the formula 1.
Abstract translation: 目的：提供一种异羟肟酸衍生物，其表现出抗衰老作用，并且改善了皮肤刺激和变色的安全性和稳定性，其制备方法和外用抗衰老皮肤制剂以及含有该衍生物的胶原酶和弹性蛋白酶表达抑制剂。 构成：异羟肟酸衍生物由式1表示，其中R 1和R 2是H，C 1 -C 10烷基或C 3 -C 6环烷基; R3是CONH，NHCO，CONR5或NR5CO（其中R5是H或C1-C10烷基）; 且R 4为 - （CH）n - （其中n为0或1）。 该方法包括使苯甲酸和4-氨基苯甲酸甲酯或4-氨基苯乙酸甲酯或苯胺与对苯二甲酸单甲酯反应制备苯甲酰胺化合物的步骤; 将苯甲酰胺化合物的氨基取代成烷基键; 水解甲基酯以制备酸; 并使所得酸与羟胺·HCl盐反应制备式1的异羟肟酸衍生物。
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