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公开(公告)号：NO952366D0
公开(公告)日：1995-06-15
申请号：NO952366
申请日：1995-06-15
Applicant: BASF AG
Inventor： HAUPT ANDREAS , JANSSEN BERND , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BARLOZZARI TERESA , QIAN XIAO-DONG
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公开(公告)号：FI945416A0
公开(公告)日：1994-11-17
申请号：FI945416
申请日：1994-11-17
Applicant: BASF AG
Inventor： HAUPT ANDREAS , EMLING FRANZ , ROMERDAHL CYNTHIA
IPC: A61K38/00 , A61K38/08 , A61P35/00 , A61P35/02 , C07K5/062 , C07K5/08 , C07K5/083 , C07K5/087 , C07K5/10 , C07K5/103 , C07K5/107 , C07K7/06 , C07K
Abstract: Novel derivates of dolastatin of formula (I) in which R , R , A, B, D, E, F, G, K, X, t, u, v, and w have the meanings stated in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.
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公开(公告)号：FI945416A
公开(公告)日：1994-11-17
申请号：FI945416
申请日：1994-11-17
Applicant: BASF AG
Inventor： HAUPT ANDREAS , EMLING FRANZ , ROMERDAHL CYNTHIA
IPC: A61K38/00 , A61K38/08 , A61P35/00 , A61P35/02 , C07K5/062 , C07K5/08 , C07K5/083 , C07K5/087 , C07K5/10 , C07K5/103 , C07K5/107 , C07K7/06 , C07K
Abstract: Novel derivates of dolastatin of formula (I) in which R , R , A, B, D, E, F, G, K, X, t, u, v, and w have the meanings stated in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.
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公开(公告)号：CA2155759A1
公开(公告)日：1994-10-13
申请号：CA2155759
申请日：1994-03-19
Applicant: BASF AG
Inventor： JANSSEN BERND , KLING ANDREAS , MUELLER STEFAN , RITTER KURT , SCHLECKER RAINER , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , TRAUGOTT ULRICH
IPC: C07D295/08 , A61K31/34 , A61K31/341 , A61K31/357 , A61K31/36 , A61K31/40 , A61K31/403 , A61K31/41 , A61K31/42 , A61K31/421 , A61K31/4245 , A61K31/425 , A61K31/426 , A61K31/433 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4412 , A61K31/4418 , A61K31/445 , A61K31/451 , A61K31/47 , A61K31/495 , A61K31/496 , A61P35/00 , C07D207/32 , C07D207/333 , C07D209/52 , C07D211/14 , C07D213/30 , C07D215/14 , C07D261/08 , C07D261/18 , C07D263/14 , C07D263/32 , C07D271/06 , C07D271/10 , C07D277/24 , C07D285/12 , C07D295/092 , C07D307/42 , C07D307/58 , C07D317/58 , C07D317/66 , C07D333/06 , C07D333/16 , C07D413/12 , C07D417/12 , C07D521/00 , C07F9/6509 , C07D295/112 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , A61K31/435 , C07D211/70
Abstract: This invention relates to 1-amino-3-phenoxy-propane-derivatives of formula (1) (in which A, B, R, Rx, X and Z are defined as in the specification described) and methods for their preparation. These compounds may be used as modulators of multi-drug resistance in cancer chemotherapy and for circumvention of resistance in the treatment of malaria.
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公开(公告)号：PL178766B1
公开(公告)日：2000-06-30
申请号：PL30935393
申请日：1993-12-04
Applicant: BASF AG
Inventor： HAUPT ANDREAS , JANSSEN BERND , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BARLOZZARI TERESA , QIAN XIAO-DONG
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Patent Agency Ranking
公开(公告)号：SG64906A1
公开(公告)日：1999-05-25
申请号：SG1996007469
申请日：1994-08-08
Applicant: BASF AG
Inventor： BOUSQUET PETER , CASTELLANO BERLANGA JOSE MARIA , FERNANDEZ BRANA MIGUEL , KEILHAUER GERHARD , MORAN MOSET MARINA , PEREZ DE VEGA MARIA JESUS , QIAN XIAO-DONG , ROMERDAHL CYNTHIA
IPC: A61K31/47 , A61K31/473 , A61P35/00 , C07D221/14 , A61K31/435
Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula 1. A compound of the Formula wherein X, X', X'' and X''', A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
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公开(公告)号：AU679479B2
公开(公告)日：1997-07-03
申请号：AU5695994
申请日：1993-12-04
Applicant: BASF AG
Inventor： HAUPT ANDREAS , JANSSEN BERND , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BARLOZZARI TERESA , QIAN XIAO-DONG
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公开(公告)号：NZ271374A
公开(公告)日：1997-05-26
申请号：NZ27137494
申请日：1994-08-08
Applicant: BASF AG
Inventor： KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BRANA MIGUEL FERNADEZ , QIAN XIAO-DONG , BOUSQUET PETER , BERLANGA JOSE MARIA CASTELLANO , MOSET MARINA MORAN , DE VEGA MARIA JESUS PEREZ
IPC: A61K31/47 , A61K31/473 , A61P35/00 , C07D221/14 , C07D221/00 , A61K31/445 , A61K31/435
Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula 1. A compound of the Formula wherein X, X', X'' and X''', A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
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公开(公告)号：NZ252147A
公开(公告)日：1996-10-28
申请号：NZ25214793
申请日：1993-05-10
Applicant: BASF AG
Inventor： HAUPT ANDREAS , EMLING FRANZ , ROMERDAHL CYNTHIA
IPC: A61K38/00 , A61K38/08 , A61P35/00 , A61P35/02 , C07K5/062 , C07K5/08 , C07K5/083 , C07K5/087 , C07K5/10 , C07K5/103 , C07K5/107 , C07K7/06 , A61K38/07
Abstract: Novel derivates of dolastatin of formula (I) in which R , R , A, B, D, E, F, G, K, X, t, u, v, and w have the meanings stated in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.
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公开(公告)号：ZA946196B
公开(公告)日：1996-02-19
申请号：ZA946196
申请日：1994-08-17
Applicant: BASF AG
Inventor： KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BRANA MIGUEL FERNANDEZ , QIAN XIAO-DONG , BOUSQUET PETER , BERLANGA JOSE MARIA CASTELLANO , MOSET MARINA MORAN , VEGA MARIA JESUS PREZ DE
IPC: A61K31/47 , A61K31/473 , A61P35/00 , C07D221/14 , A61K , C07D
Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula 1. A compound of the Formula wherein X, X', X'' and X''', A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
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