公开(公告)号：DE10018251C2

公开(公告)日：2003-08-14

申请号：DE10018251

申请日：2000-04-13

Applicant: LEICA MICROSYSTEMS

Inventor： GANSER MICHAEL ,  WEIS ALBRECHT ,  STENZEL RUEDIGER

IPC: B23K26/00 ,  B23K26/10 ,  B23K26/40 ,  G01N1/04 ,  G01N1/28 ,  G02B21/32 ,  G01N33/48 ,  C12M1/42 ,  G02B21/26

Abstract: The invention relates to a device for laser cutting preparations which comprises an XY table ( 2 ) that defines a table surface ( 4 ). A holding device ( 14 ) for accommodating an object support ( 6 ) with a preparation ( 8 ) is arranged above the table surface ( 4 ) and is joined to the XY table ( 2 ) in a manner that permits it to be displaced in the Y direction ( 20 a) in the X direction ( 22 a). An open working space ( 16 ) is defined between the holding device ( 14 ) and the table surface ( 4 ). A catching device ( 10 ), which has at least one receptacle ( 12 ) for catching a preparation part that has been cut out, can be introduced into said working space. The invention also relates to a microscope that is equipped with the aforementioned laser cutting device.

公开(公告)号：DE10102034A1

公开(公告)日：2002-08-08

申请号：DE10102034

申请日：2001-01-18

Applicant: LEICA MICROSYSTEMS

Inventor： GANSER MICHAEL ,  WEIS ALBRECHT

IPC: G01N1/04 ,  G01N1/06 ,  G01N1/28 ,  G01N35/00 ,  G02B21/34

公开(公告)号：DE10043504C2

公开(公告)日：2002-07-04

申请号：DE10043504

申请日：2000-09-01

Applicant: LEICA MICROSYSTEMS

Inventor： GANSER MICHAEL

IPC: G01N33/48 ,  G01N1/04 ,  G01N1/28

Abstract: A laser beam generates a perforation with links (26-28) along a cutting line (25) enclosing a sample area (23) of interest. The perforation has two or more links to break up the cutting line. These links connect the sample area of interest to a surrounding specimen (4). The links are then ripped off with a single laser impulse directed at the sample area of interest to separate it from the surrounding specimen.

公开(公告)号：DE4231379C2

公开(公告)日：2001-09-13

申请号：DE4231379

申请日：1992-09-19

Applicant: LEICA MICROSYSTEMS

Inventor： GANSER MICHAEL ,  FELGENHAUER KLAUS ,  SCHALZ KARL-JOSEF

IPC: G02B21/24 ,  G02B21/26

Abstract: PCT No. PCT/DE93/00797 Sec. 371 Date Apr. 24, 1995 Sec. 102(e) Date Apr. 24, 1995 PCT Filed Sep. 3, 1993 PCT Pub. No. WO94/07172 PCT Pub. Date Mar. 31, 1994A microscope (1) is described which has an adjustment knob (2) arranged on the microscope (1) and an encoder (6) assigned to the adjustment knob (2). The encoder (6) is connected to a control device (3). The control device (3) is assigned positioning motors (4, 14, 18, 23, 24) for motorized setting of different microscope functions. The preselected function which can be controlled by motor is preselected via switches (7, 11, 15, 19, 21) arranged on the microscope (1) and triggered via the control device (3) as a function of the encoder pulses generated by the adjustment knob (2). The motor drives are assigned sensors (8) which detect the operating position of the activated microscope function. When the maximum operating position is reached, a braking motor (9) connected to the adjustment knob (2) is activated via the control device (3) and renders the rotation of the adjustment knob (2) more difficult up to complete blockage.

公开(公告)号：DE19906422A1

公开(公告)日：2000-05-31

申请号：DE19906422

申请日：1999-02-16

Applicant: LEICA MICROSYSTEMS

Inventor： WEIS ALBRECHT ,  GANSER MICHAEL ,  STENZEL RUEDIGER

IPC: B01L9/00 ,  G01N35/00 ,  G02B21/26 ,  G02B21/34

Abstract: The holder has a pressed part (1) contacting the object carrier (3) at two pressing points (8,9). One point (9) lies on the x-side and the other point (8) lies on the y-side. Preferred Features: The pressed part (1) is a one-piece lever (H1) pivoting about an axis (11) fixed to the bearing part (2). The lever can additionally be moved in its longitudinal direction. The pressed part is fixed to a spring (10). The spring is provided with a magnetic holder.

公开(公告)号：DE19812599A1

公开(公告)日：1999-09-30

申请号：DE19812599

申请日：1998-03-23

Applicant: LEICA MICROSYSTEMS

Inventor： GANSER MICHAEL

IPC: G01N15/14 ,  G02B21/00 ,  G02B21/26 ,  G02B21/36

Abstract: According to the inventive video microscopy method, an image produced by a microscope (1) of an object (9) on a microscope table (7) is recorded with a video camera (10), digitised, temporarily stored and displayed on the monitor (13) of a personal computer (12). An image detail (15) is selected at a known magnification V1. Its image co-ordinates r 1 = (x1,y1) relative to the image centre (18) of the monitor screen (17) are determined true to scale. After the magnification is switched from the magnification V1 to a magnification Vm, the position of the image detail (15) on the monitor screen (17) is retained whilst the microscope table (7) is moved around ( r 1(1/Vm-1/V1) in accordance with the signs.

公开(公告)号：DE102014110575B4

公开(公告)日：2017-10-12

申请号：DE102014110575

申请日：2014-07-25

Applicant: LEICA MICROSYSTEMS

Inventor： GANSER MICHAEL

IPC: G02B21/06 ,  G02B21/00

Abstract: Verfahren zum optischen Untersuchen und/oder Manipulieren einer mikroskopischen Probe gekennzeichnet durch folgende Schritte: a. Positionieren der Probe in einer Probensollposition vor einem Objektiv (1), das sowohl in einem Beobachtungsstrahlengang (3) als auch in einem Beleuchtungsstrahlengang (4) eines Mikroskops angeordnet ist, welches einen Hauptstrahlteiler (2) aufweist, der den Beobachtungsstrahlengang (3) von dem Beleuchtungsstrahlengang (4) trennt b. Auswählen wenigstens einer eine Beleuchtungsoptik umfassenden Beleuchtungseinrichtung (8, 10, 16), aus einer Vielzahl von unterschiedlichen Beleuchtungseinrichtungen (8, 10, 16) in Abhängigkeit von der Art der Probe und/oder der Art der durchzuführenden Untersuchung und/oder Manipulation der Probe, c. Koppeln der ausgewählten Beleuchtungseinrichtung (8, 10, 16) in einer vordefinierten Sollposition an eine mechanische Ankoppelschnittstelle (20, 21, 22) des Mikroskops (6), d. Lenken eines von der Beleuchtungseinrichtung (8, 10, 16) ausgehenden Beleuchtungslichts entlang des Beleuchtungsstrahlenganges (4) mittels einer in einem Mikroskopgehäuse (6) des Mikroskops angeordneten optischen Vorrichtung (5) zu dem Hauptstrahlteiler (2) und von dort zu dem Objektiv (1) und durch das Objektiv (1) hindurch auf die Probe, wobei auf dem Lichtweg des Beleuchtungslichts (7, 9, 17) zwischen der optischen Vorrichtung (5) und dem Objektiv (1) kein abbildendes und/oder fokussierendes und/oder defokussierendes optisches Bauteil angeordnet ist.

公开(公告)号：DE102013206466B4

公开(公告)日：2014-12-11

申请号：DE102013206466

申请日：2013-04-11

Applicant: LEICA MICROSYSTEMS

Inventor： WEISS ALBRECHT ,  GANSER MICHAEL

IPC: G01N21/64 ,  G01B9/04 ,  G02B21/00

Abstract: Die Erfindung betrifft ein Fluoreszenzmikroskop (13) mit einer Beleuchtungseinrichtung (20, 21, 23, 25, 26) zur Erzeugung eines Beleuchtungsstrahlengangs, der eine fluoreszierende Probe (15) zur Abgabe von Fluoreszenzstrahlung anregt, und einer Abbildungseinrichtung (1, 2, 12, 14, 24) umfassend ein Objektiv (14) zur Erzeugung eines Abbildungsstrahlengangs zur Erzeugung eines Bildes zumindest eines Teils der fluoreszierenden Probe (15), wobei die Abbildungseinrichtung ein Emissionsfilter zur Selektion von Wellenlängen aus dem Spektrum des Abbildungsstrahlengangs aufweist, wobei als Emissionsfilter ein abbildungsseitiges Farbverlaufsfilter (8) in einer zur Pupillenebene des Abbildungsstrahlengangs konjugierten Ebene (6) eingesetzt ist.

公开(公告)号：DE102005024867C5

公开(公告)日：2009-08-27

申请号：DE102005024867

申请日：2005-05-31

Applicant: LEICA MICROSYSTEMS

Inventor： GANSER MICHAEL

IPC: G02B21/00 ,  G02B21/36

Abstract: The system has a camera (1) for photographing microscopic pictures. An adjusting unit (6), focus drive, table drive and microscope lamp are provided for changing the position of a microscope, where the adjusting unit is connected with a camera, such that a determined picture mode of the camera is adjusted based on the microscope adjustment. The lamp is else modified based on the adjusted picture mode of the camera. Independent claims are also included for: (1) A method for picture transmission with a microscope; and (2) A computer program product with a program code structure, which is stored on a computer readable data carrier for picture transmission.

公开(公告)号：DE102006022276A1

公开(公告)日：2007-11-15

申请号：DE102006022276

申请日：2006-05-11

Applicant: LEICA MICROSYSTEMS

Inventor： WEIS ALBRECHT ,  GANSER MICHAEL

IPC: G02B21/36

Abstract: A microscope comprising a camera connection in a image beam path is suggested. A camera adapter and a camera can be adapted to the camera connection, and the microscope can be used to reproduce the image of a sample on a sensor of the camera. Imaging of the beam path in the camera adapter comprises an intermediate imaging with a pupil plane having reduced beam diameter next to the pupil plane, and at least one optical means can be inserted into the reproduction beam path in the region of the reduced beam cross-section. An optical means or an interchangeable device comprising a plurality of optical means, such as filters, plane-parallel plates or wedge plate, is integrated into the pupil plane in the camera adapter.