公开(公告)号：WO2008056891A1

公开(公告)日：2008-05-15

申请号：PCT/KR2007/004971

申请日：2007-10-11

Applicant: KOREA BASIC SCIENCE INSTITUTE ,  KIM, Hae Jin ,  LEE, Jin Bae ,  LEE, Soon Chang

Inventor： KIM, Hae Jin ,  LEE, Jin Bae ,  LEE, Soon Chang

IPC: B82B3/00

CPC classification number: H01M4/485 ,  C01B3/001 ,  C01B33/12 ,  C01B33/18 ,  C04B35/14 ,  C04B35/62227 ,  C04B35/6224 ,  H01M8/04216 ,  Y02E60/324 ,  Y02P70/56

Abstract: Disclosed herein are a method of preparing Li-doped silica nanotubes using an anodic aluminum oxide (AAO) template, and a method of storing energy using the prepared Li-doped silica nanotubes. Unlike prior methods for preparing metal nanotubes, according to the disclosed preparation method, the Li-doped silica nanotubes having a uniform size can be easily obtained in mild conditions using a lithium precursor, a silica sol and an anodic aluminum oxide template. The preparation method comprises adsorbing the lithium precursor and the silica sol on the surface of the AAO template, drying the lithium precursor and the silica sol, adsorbed onto the AAO template, in a vacuum, to form nanotubes, and then drying the nanotubes. The Li-doped silica nanotubes prepared according to the disclosed method can be used as economical hydrogen storage materials, electrode materials for lithium secondary batteries, or energy storage sources for automobiles or other transportation means.

Abstract translation: 本文公开了使用阳极氧化铝（AAO）模板制备掺杂锂的二氧化硅纳米管的方法，以及使用制备的Li掺杂的二氧化硅纳米管来储存能量的方法。 与现有的制备金属纳米管的方法不同，根据所公开的制备方法，可以使用锂前体，二氧化硅溶胶和阳极氧化铝模板在温和条件下容易地获得具有均匀尺寸的Li掺杂二氧化硅纳米管。 该制备方法包括将锂前体和二氧化硅溶胶吸附在AAO模板的表面上，在真空中干燥吸附在AAO模板上的锂前体和二氧化硅溶胶，形成纳米管，然后干燥纳米管。 根据所公开的方法制备的掺杂Li的二氧化硅纳米管可以用作经济的储氢材料，锂二次电池的电极材料，或用于汽车或其他运输工具的储能源。

公开(公告)号：WO2007139244A1

公开(公告)日：2007-12-06

申请号：PCT/KR2006/002087

申请日：2006-05-30

Applicant: KOREA BASIC SCIENCE INSTITUTE ,  LEE, Ha Jin ,  LEE, Haeseong ,  NGUYEN, Tinh

Inventor： LEE, Ha Jin ,  LEE, Haeseong ,  NGUYEN, Tinh

IPC: C01B31/02 ,  B82B3/00

CPC classification number: B82Y30/00 ,  B82Y40/00 ,  C01B32/174 ,  C01B2202/02 ,  C01B2202/06 ,  C01B2202/28

Abstract: Disclosed is a carbon nanotube having a modified surface through transition metal coordination. The carbon nanotube includes a carbon nanotube having a surface where a π-electron exists, and a transition metal ion being coordinate-bonded by electron -sharing of the π-electron existing in the surface of the carbon nanotube. A carbon nanotube further includes an organic material coordinate-bonded to the transition metal ion. A method of manufacturing the carbon nanotube is also disclosed.

Abstract translation: 公开了具有通过过渡金属配位的改性表面的碳纳米管。 碳纳米管包括具有p电子存在的表面的碳纳米管和通过存在于碳纳米管表面的p电子的电子共享来配位的过渡金属离子。 碳纳米管还包括与过渡金属离子配位键合的有机材料。 还公开了制造碳纳米管的方法。

公开(公告)号：WO2005075993A1

公开(公告)日：2005-08-18

申请号：PCT/KR2004/000256

申请日：2004-02-10

Applicant: KOREA BASIC SCIENCE INSTITUTE ,  AHN, Yeong Hee ,  YOO, Jong Shin ,  KIM, Jin Young ,  CHO, Kun

Inventor： AHN, Yeong Hee ,  YOO, Jong Shin ,  KIM, Jin Young ,  CHO, Kun

IPC: G01N33/53

CPC classification number: G01N33/6848 ,  A61K31/155 ,  G01N33/6803 ,  G01N33/6842 ,  G01N2458/15

Abstract: Disclosed is a method of analyzing mass of the phosphoproteins or phosphopeptides and of analyzing phosphorylated positions at a phosphoprotein or phosphopeptide, comprising the steps of: 1) dephosphorylating at least one Ser and/or Thr residue of the phosphoprotein or phosphopeptide; 2) tagging the dephosphorylated amino acid residues with a tag having a R-L-G moiety wherein R is a nucleophilic functional group that selectively bind with dephosphorylated amino acid residues, G is selected from the group consisting of guanidine moiety or protected guanidine moiety such as a mono-N-protected guanidino group, a di-N,N'-protected guanidino group and an N'-protected guanidino group, and L is a linker linking the R and the G; and 3) subjecting the tagged proteins or peptides to mass spectrometry. The method is capable of precisely analyzing mass of phosphoproteins of trace amounts as well as positions of phosphoryated amino acids.

Abstract translation: 公开了一种分析磷蛋白或磷酸肽的质量并分析磷蛋白或磷酸肽的磷酸化位置的方法，包括以下步骤：1）使磷酸蛋白或磷酸肽的至少一个Ser和/或Thr残基去磷酸化; 2）用具有RLG部分的标签标记去磷酸化的氨基酸残基，其中R是与去磷酸化的氨基酸残基选择性结合的亲核官能团，G选自胍部分或被保护的胍部分，例如单 - N-保护的胍基，二-N，N'保护的胍基和N'保护的胍基，L是连接R和G的连接基团; 和3）对标记的蛋白质或肽进行质谱分析。 该方法能够精确分析痕量的磷蛋白质量以及磷酸化氨基酸的位置。

公开(公告)号：WO2003104775A1

公开(公告)日：2003-12-18

申请号：PCT/KR2002/001659

申请日：2002-09-02

Applicant: KOREA BASIC SCIENCE INSTITUTE ,  HA, Kwon, Soo ,  YUK, Jong, Seol ,  YI, Sun, Ju ,  LEE, Hyeon, Gon ,  KWON, Kyung, Hoon

Inventor： HA, Kwon, Soo ,  YUK, Jong, Seol ,  YI, Sun, Ju ,  LEE, Hyeon, Gon ,  KWON, Kyung, Hoon

IPC: G01N21/25

CPC classification number: G01N21/553

Abstract: The present invention provides a method for protein chip analysis by using surface plasmon resonance spectroscopic image technology. A protein chip with a plurality of spots, arranged at a specific interval in vertical and horizontal directions, is mounted on a x-y stage, and p-polarized beams that passed through a prism are sequentially irradiated on each spot of the protein chip. The light signal reflected from each spot of the protein chip is collected into a spectrometer and its surface plasmon resonance wavelength is determined. This surface plasmon resonance wavelength value is represented by a color at the position of each protein spot to obtain a two dimensional image. Otherwise, the surface plasmon resonance wavelength value is allocated to a z-coordinate value to obtain a three-dimensional image.

Abstract translation: 本发明提供了使用表面等离子体共振光谱图像技术进行蛋白质芯片分析的方法。 将具有多个点的蛋白质芯片以垂直和水平方向的特定间隔安装在x-y平台上，并且通过棱镜的p偏振光束依次照射在蛋白质芯片的每个点上。 从蛋白质芯片的每个点反射的光信号被收集到光谱仪中，并且确定其表面等离子体共振波长。 该表面等离子体共振波长值由每个蛋白点的位置处的颜色表示，以获得二维图像。 否则，将表面等离子体共振波长值分配给z坐标值以获得三维图像。

公开(公告)号：EP3900725B1

公开(公告)日：2024-08-28

申请号：EP19899095.4

申请日：2019-12-19

IPC: A61K31/496 ,  A61P3/10 ,  A61P1/16 ,  A23L33/10

CPC classification number: A61P1/16 ,  A61P3/10 ,  A61K31/496

公开(公告)号：EP3706159A1

公开(公告)日：2020-09-09

申请号：EP18874845.3

申请日：2018-11-01

Applicant: Korea Basic Science Institute

Inventor： CHOI, Yong Sup ,  LEE, Kang Il ,  SEOK, Dong Chan ,  JANG, Soo Ouk ,  KIM, Jong Sik ,  YOO, Seung Ryul

IPC: H01L21/3105 ,  H01L21/311 ,  H01L21/02 ,  H01L21/67

Abstract: The present invention relates to an atomic layer polishing method comprising: the steps of: scanning the surface of a specimen to measure a peak site on the specimen surface; spraying toward the measured peak site a gas containing an element capable of binding to a first atom, which is an ingredient of the material of the specimen to form a first reaction gas layer in which the first reaction gas binds to the first atom on the surface of the peak; and projecting ions of inert gas to the peak site on which the first reaction gas layer is deposited to separate the first atom bound to the first reaction gas from the specimen.

公开(公告)号：EP3406250B1

公开(公告)日：2020-03-18

申请号：EP18173590.3

申请日：2018-05-22

Applicant: Korea Basic Science Institute

Inventor： KIM, Gun Hwa ,  PARK, Joo Hyun ,  LEE, Min Ji

IPC: A61K31/4545 ,  A61K31/538 ,  A61P1/16 ,  A61P3/10

公开(公告)号：EP3406250A1

公开(公告)日：2018-11-28

申请号：EP18173590.3

申请日：2018-05-22

Applicant: Korea Basic Science Institute

Inventor： KIM, Gun Hwa ,  PARK, Joo Hyun ,  LEE, Min Ji

IPC: A61K31/4545 ,  A61K31/538 ,  A61P1/16 ,  A61P3/10

Abstract: The present invention relates to a pharmaceutical composition for the prevention or treatment of diabetes or fatty liver comprising a CYP4A (cytochrome P450A) inhibitor as an active ingredient. The compound of the present invention has activities of promoting glucose uptake into hepatocytes, inhibiting fat accumulation in liver cells, and inhibiting reactive oxygen production in mitochondria, and thus can be very usefully used for the development of a therapeutic agent for diabetes or fatty liver.

公开(公告)号：EP3308802A1

公开(公告)日：2018-04-18

申请号：EP16807715.4

申请日：2016-05-19

Applicant: Korea Basic Science Institute ,  Korea Research Institute of Chemical Technology

Inventor： HONG, Kwan Soo ,  PARK, Hye Sun ,  NAM, Sang Hwan ,  SUH, Yung Doug

IPC: A61K49/04 ,  A61K49/06

Abstract: Provided are a hydrophilic particle, a method for manufacturing the same, and a contrasting agent using the same. More specifically, the hydrophilic particle according to the inventive concept may include a hydrophobic particle, and an amphiphilic organic dye directly absorbed on a surface of the hydrophobic particle. In this case, the hydrophobic particle includes a center particle, and a hydrophobic ligand covering a surface of the center particle, and the amphiphilic organic dye may be combined to the hydrophobic ligand by a hydrophobic interaction. The hydrophilic particle may have a surface zeta potential lower than a surface zeta potential of the amphiphilic organic dye.

Abstract translation: 提供亲水性颗粒，其制造方法和使用其的对比剂。 更具体地，根据本发明构思的亲水颗粒可以包括疏水颗粒和直接吸附在疏水颗粒表面上的两亲有机染料。 在这种情况下，疏水性颗粒包括中心颗粒和覆盖中心颗粒表面的疏水性配体，并且两亲性有机染料可以通过疏水性相互作用与疏水性配体结合。 亲水性颗粒可具有低于两亲有机染料的表面ζ电位的表面ζ电位。

公开(公告)号：EP3002996A1

公开(公告)日：2016-04-06

申请号：EP15191835.6

申请日：2012-06-01

Applicant: Korea Basic Science Institute

Inventor： YOO, Suk Jae ,  KIM, Seong Bong

IPC: H05H1/46 ,  H01L21/205 ,  C23C16/50 ,  H01J37/32 ,  H01J37/34

Abstract: The present invention is about a neutral particle beam source for producing a high density plasma in high vacuum and a thin film deposition system employing said neutral particle beam source,
According to the present invention, the plasma is generated by using microwave through the microwave irradiating equipment and a magnetic field by more than one pair of belt type magnets and the high density plasma can be accomplished by maximizing the plasma confinement effect inducing an electron returning trajectory in accordance with the above continuous structure of the belt type magnet in combination with the microwave irradiating equipment.

Abstract translation: 本发明涉及一种用于在高真空中制造高密度等离子体的中性粒子束源和采用所述中性粒子束源的薄膜沉积系统。根据本发明，通过使用微波通过微波照射设备产生等离子体 并且通过多于一对带式磁体的磁场和高密度等离子体可以通过根据带式磁体的上述连续结构最大化引起电子返回轨迹的等离子体约束效应与微波照射 设备。