公开(公告)号：US20240361238A1

公开(公告)日：2024-10-31

申请号：US18309468

申请日：2023-04-28

Applicant: TEXAS INSTRUMENTS INCORPORATED

Inventor： Pulak SARANGI ,  Kaichien TSAI ,  Boyu SHEN ,  Anand G. DABAK

IPC: G01N21/53

CPC classification number: G01N21/53 ,  G01N2201/0698 ,  G01N2201/1247 ,  G01N2201/129

Abstract: In some examples, a method includes transmitting first light pulses according to a pre-determined pulse pattern in a first measurement period. The method also includes transmitting second light pulses according to the pre-determined pulse pattern in a second measurement period consecutive to the first measurement period, in which at least some of the first and second light pulses being unequally spaced in time across the first and second measurement periods. The method also includes receiving first detection signals representing detection of the first light pulses. The method also includes receiving second detection signals representing detection of the second light pulses. The method also includes providing a first light scattering measurement signal representing the first measurement period responsive to the first detection signals. The method also includes providing a second light scattering measurement signal representing the second measurement period responsive to the second detection signals.

公开(公告)号：US09935023B2

公开(公告)日：2018-04-03

申请号：US15630385

申请日：2017-06-22

Applicant: Renesas Electronics Corporation

Inventor： Toshikazu Hanawa ,  Kazuhide Fukaya ,  Kentaro Yamada

IPC: G01L21/30 ,  G01R31/00 ,  H01L21/66 ,  H01L21/311 ,  H01L21/768 ,  H01L23/522 ,  H01L23/532 ,  G01N21/73 ,  G01N21/84 ,  G01N21/68 ,  H01J37/32

CPC classification number: H01L22/26 ,  G01N21/68 ,  G01N21/73 ,  G01N21/84 ,  G01N2021/8411 ,  G01N2021/8427 ,  G01N2201/1247 ,  H01J37/32963 ,  H01J2237/334 ,  H01L21/31116 ,  H01L21/76802 ,  H01L21/76846 ,  H01L21/76877 ,  H01L23/5226 ,  H01L23/53223 ,  H01L23/53266 ,  H01L23/5329

Abstract: A via hole is accurately formed in an interlayer insulating film over a metal wiring. Of emission spectra of plasma to be used for dry etching of the interlayer insulating film, the emission intensities of at least CO, CN, and AlF are monitored such that an end point of the dry etching of the interlayer insulating film is detected based on the emission intensities thereof.

公开(公告)号：US09711423B2

公开(公告)日：2017-07-18

申请号：US15205069

申请日：2016-07-08

Applicant: Renesas Electronics Corporation

Inventor： Toshikazu Hanawa ,  Kazuhide Fukaya ,  Kentaro Yamada

IPC: G01L21/30 ,  G01R31/00 ,  H01L21/66 ,  H01L21/311 ,  H01L21/768 ,  H01L23/522 ,  H01L23/532 ,  G01N21/73 ,  G01N21/84

CPC classification number: H01L22/26 ,  G01N21/68 ,  G01N21/73 ,  G01N21/84 ,  G01N2021/8411 ,  G01N2021/8427 ,  G01N2201/1247 ,  H01J37/32963 ,  H01J2237/334 ,  H01L21/31116 ,  H01L21/76802 ,  H01L21/76846 ,  H01L21/76877 ,  H01L23/5226 ,  H01L23/53223 ,  H01L23/53266 ,  H01L23/5329

Abstract: A via hole is accurately formed in an interlayer insulating film over a metal wiring. Of emission spectra of plasma to be used for dry etching of the interlayer insulating film, the emission intensities of at least CO, CN, and AlF are monitored such that an end point of the dry etching of the interlayer insulating film is detected based on the emission intensities thereof.

公开(公告)号：US09311521B2

公开(公告)日：2016-04-12

申请号：US14233002

申请日：2012-07-27

Applicant: Jonas Erjefält

Inventor： Jonas Erjefält

IPC: G06K9/00 ,  G06T7/00 ,  G01N33/50 ,  G01N1/30

CPC classification number: G06K9/00147 ,  G01N1/30 ,  G01N21/4795 ,  G01N21/77 ,  G01N21/78 ,  G01N33/5005 ,  G01N2021/7786 ,  G01N2201/1247 ,  G06K9/0014 ,  G06T7/0012

Abstract: A method for differentiating areas in a series of digital images, the method comprising the steps of: providing a series of images comprising undetermined marker areas; evaluating every image 1n for 1≦n≦N according to predetermined selection criteria and defining image marker areas as undetermined marker areas fulfilling the predetermined selection criteria; providing a new image 1new; and inserting new image marker areas in the new image 1new, said new image marker areas having the same shape and location as image marker areas present in image 1n but not in image 1n−1, and said new image marker areas being identifiable in 1new by a unique feature. Further, the application discloses a method for visualizing cell populations in tissue sections of a histological sample. Further, the application discloses a method for visualizing three-dimensional distribution of multiple cell populations in a histological sample.

Abstract translation: 一种用于区分一系列数字图像中的区域的方法，所述方法包括以下步骤：提供包括未确定标记区域的一系列图像; 根据预定的选择标准评估每个图像1n为1＆nlE; n＆nlE; N，并将图像标记区域定义为满足预定选择标准的未确定标记区域; 提供新的图像1新; 并在新图像1中插入新的图像标记区域，所述新图像标记区域具有与图像1n中但不在图像1n-1中存在的图像标记区域相同的形状和位置，并且所述新图像标记区域可以通过 一个独特的功能。 此外，该申请公开了一种在组织学样品的组织切片中可视化细胞群的方法。 此外，本申请公开了一种用于在组织学样本中可视化多个细胞群体的三维分布的方法。

公开(公告)号：US20130252346A1

公开(公告)日：2013-09-26

申请号：US13795554

申请日：2013-03-12

Applicant: SINGULEX, INC.

Inventor： Philippe Goix ,  Robert Puskas ,  John Todd ,  Richard Livingston ,  Douglas Held ,  Allan H.B. Wu

IPC: G01N33/68

CPC classification number: G01N33/6887 ,  G01N15/06 ,  G01N15/1459 ,  G01N21/6428 ,  G01N33/577 ,  G01N33/582 ,  G01N2015/0693 ,  G01N2015/1006 ,  G01N2015/1486 ,  G01N2201/1247 ,  G01N2201/12761 ,  G01N2800/32 ,  G01N2800/324 ,  G01N2800/52 ,  Y10T436/105831

Abstract: The invention provides methods, compositions, kits, and systems for the sensitive detection of cardiac troponin, Such methods, compositions, kits, and systems are useful in diagnosis, prognosis, and determination of methods of treatment in conditions that involve release of cardiac troponin.

Abstract translation: 本发明提供用于敏感检测心肌肌钙蛋白的方法，组合物，试剂盒和系统。这种方法，组合物，试剂盒和系统可用于诊断，预后和确定涉及心肌肌钙蛋白释放的病症中的治疗方法。

公开(公告)号：WO2009081109A1

公开(公告)日：2009-07-02

申请号：PCT/GB2008/004180

申请日：2008-12-18

Applicant: VANGUARD SENSOR TECHNOLOGIES LIMITED ,  JONES, Nigel ,  ASHBY, Ron

Inventor： JONES, Nigel ,  ASHBY, Ron

IPC: G01N21/59 ,  G01N21/94 ,  G01V8/20 ,  G01B11/06 ,  G01B11/24

CPC classification number: G01V8/12 ,  G01B11/0683 ,  G01B11/2433 ,  G01N21/94 ,  G01N2021/5957 ,  G01N2021/5961 ,  G01N2021/945 ,  G01N2201/0696 ,  G01N2201/1247

Abstract: A monitoring system is disclosed, designed to detect the depth of deposition of a substance on a' surface (12), such as the depth of dust in a ventilation shaft. The monitoring system includes a light source (14) and a sensor (16, 30). The light source is arranged to transmit light across a detection surface and the sensor is on the other side of the detection surface. When a substance, such as dirt or grease, is deposited on the surface it obstructs the light and the amount of light reaching the sensor decreases. A processing means (26) detects the decrease in light and from this the depth of the deposition on the surface can be calculated. Preferably the sensor comprises a CCD array (32), and the substance throws a shadow on the array. The processing means can then determine the depth of the substance from the position on the array of the edge of the shadow. Preferably the monitoring system is placed in a low power 'sleep' mode in between intermittent operations for detecting the depth of the substance. In this, way, it can be battery operated and the battery life is preserved.

Abstract translation: 公开了一种监测系统，其设计用于检测物质在“表面（12）上的沉积深度，例如通风轴中灰尘的深度。 监测系统包括光源（14）和传感器（16,30）。 光源被布置成将光透过检测表面，并且传感器位于检测表面的另一侧。 当物质如污垢或油脂沉积在表面上时，它会阻挡光线，并且到达传感器的光量减少。 处理装置（26）检测光的减少，从而可以计算出表面上沉积的深度。 优选地，传感器包括CCD阵列（32），并且该物质在阵列上投射阴影。 处理装置然后可以从阴影边缘的阵列上的位置确定物质的深度。 优选地，监测系统在用于检测物质深度的间歇操作之间被置于低功率“睡眠”模式。 在这种方式下，可以进行电池操作，并保持电池寿命。

公开(公告)号：WO2008048371A2

公开(公告)日：2008-04-24

申请号：PCT/US2007008394

申请日：2007-04-04

Applicant: SINGULEX INC ,  GOIX PHILIPPE ,  PUSKAS ROBERT ,  TODD JOHN ,  LIVINGSTON RICHARD ,  HELD DOUGLAS

Inventor： GOIX PHILIPPE ,  PUSKAS ROBERT ,  TODD JOHN ,  LIVINGSTON RICHARD ,  HELD DOUGLAS

IPC: B01J19/00 ,  C40B30/04 ,  G01N21/63 ,  G01N33/566 ,  G01N33/68 ,  G01N35/10

CPC classification number: G01N33/6887 ,  G01N15/06 ,  G01N15/1459 ,  G01N21/6428 ,  G01N33/577 ,  G01N33/582 ,  G01N2015/0693 ,  G01N2015/1006 ,  G01N2015/1486 ,  G01N2201/1247 ,  G01N2201/12761 ,  G01N2800/32 ,  G01N2800/324 ,  G01N2800/52 ,  Y10T436/105831

Abstract: Disclosed are methods, kits, and compositions for the highly sensitive detection of molecules. The methods, kits, and compositions are useful in determining concentrations of molecules in samples to levels of 1 femtomolar, 1 attomolar, or lower. The methods, kits, and compositions also allow the determination of concentration over a wide range, e.g., 7-log range, without need for sample dilution.

Abstract translation: 公开了用于分子的高灵敏度检测的方法，试剂盒和组合物。 方法，试剂盒和组合物可用于测定样品中分子的浓度为1飞摩尔，1 attomolar或更低的水平。 方法，试剂盒和组合物还允许在宽范围内测定浓度，例如7-log范围，而不需要样品稀释。

公开(公告)号：WO2008079032A3

公开(公告)日：2008-08-28

申请号：PCT/NZ2007000391

申请日：2007-12-21

Applicant: PHOTONIC INNOVATIONS LTD ,  WILSON ANDREW COLIN ,  GEURSEN REECE WIM ,  SANDEEP SRI KUMAR

Inventor： WILSON ANDREW COLIN ,  GEURSEN REECE WIM ,  SANDEEP SRI KUMAR

IPC: G01N21/39 ,  G01J3/42 ,  G01N21/35

CPC classification number: G01N21/3504 ,  G01J3/4338 ,  G01N21/031 ,  G01N21/39 ,  G01N2021/3148 ,  G01N2021/399 ,  G01N2201/0221 ,  G01N2201/0612 ,  G01N2201/06146 ,  G01N2201/0694 ,  G01N2201/1211 ,  G01N2201/1247

Abstract: A gas detector (10) that is arranged to sense the concentration levels of target gases oxygen, methane, carbon monoxide, and hydrogen sulphide, within a gas sample from an environment surrounding the detector. The gas detector (10) comprises laser sources (12a-12d) that are arranged to transmit radiation through the gas sample at four target wavelengths that correspond approximately to the optimum absorption wavelengths of each of the target gases and an optical detector (16) that is arranged to sense the intensity of the radiation transmitted through the gas sample at each of the target wavelengths. A control system (22) generates representative concentration level information for the target gases based on the level of absorption of the radiation transmitted.

Abstract translation: 一种气体检测器（10），其被布置成感测来自环境周围环境的气体样品中的目标气体氧气，甲烷，一氧化碳和硫化氢的浓度水平。 气体检测器（10）包括激光源（12a-12d），其被布置成以四个目标波长透射通过气体样品的辐射，其大致对应于每个目标气体的最佳吸收波长;以及光学检测器（16）， 布置成感测在每个目标波长处透射通过气体样品的辐射的强度。 控制系统（22）基于所发射的辐射的吸收水平产生目标气体的代表性浓度水平信息。

公开(公告)号：WO2008079032A2

公开(公告)日：2008-07-03

申请号：PCT/NZ2007/000391

申请日：2007-12-21

Applicant: PHOTONIC INNOVATIONS LIMITED ,  WILSON, Andrew, Colin ,  GEURSEN, Reece, Wim ,  SANDEEP, Sri, Kumar

Inventor： WILSON, Andrew, Colin ,  GEURSEN, Reece, Wim ,  SANDEEP, Sri, Kumar

CPC classification number: G01N21/3504 ,  G01J3/4338 ,  G01N21/031 ,  G01N21/39 ,  G01N2021/3148 ,  G01N2021/399 ,  G01N2201/0221 ,  G01N2201/0612 ,  G01N2201/06146 ,  G01N2201/0694 ,  G01N2201/1211 ,  G01N2201/1247

Abstract: A gas detector (10) that is arranged to sense the concentration levels of target gases oxygen, methane, carbon monoxide, and hydrogen sulphide, within a gas sample from an environment surrounding the detector. The gas detector (10) comprises laser sources (12a-12d) that are arranged to transmit radiation through the gas sample at four target wavelengths that correspond approximately to the optimum absorption wavelengths of each of the target gases and an optical detector (16) that is arranged to sense the intensity of the radiation transmitted through the gas sample at each of the target wavelengths. A control system (22) generates representative concentration level information for the target gases based on the level of absorption of the radiation transmitted.

Abstract translation: 气体检测器（10）被布置为感测来自检测器周围的环境的气体样本内的目标气体氧气，甲烷，一氧化碳和硫化氢的浓度水平。 气体检测器（10）包括激光源（12a-12d），该激光源被布置成在四个目标波长处传输通过气体样本的辐射，所述四个目标波长大致对应于每个目标气体的最佳吸收波长和光学检测器 被布置为感测在每个目标波长处透过气体样本的辐射的强度。 控制系统（22）基于传输的辐射的吸收水平产生目标气体的代表性浓度水平信息。

公开(公告)号：WO2013015740A1

公开(公告)日：2013-01-31

申请号：PCT/SE2012/050851

申请日：2012-07-27

Applicant: MEDETECT AB ,  ERJEFÄLT, Jonas

Inventor： ERJEFÄLT, Jonas

IPC: G06T7/00 ,  G06T9/00 ,  G06K9/62 ,  G06T11/00

CPC classification number: G06K9/00147 ,  G01N1/30 ,  G01N21/4795 ,  G01N21/77 ,  G01N21/78 ,  G01N33/5005 ,  G01N2021/7786 ,  G01N2201/1247 ,  G06K9/0014 ,  G06T7/0012

Abstract: A method for differentiating areas in a series of digital images, the method comprising the steps of: providing a series of images comprising undetermined marker areas; evaluating every image l n for 1≤n≤N according to predetermined selection criteria and defining image marker areas as undetermined marker areas fulfilling the predetermined selection criteria; providing a new image l new ; and inserting new image marker areas in the new image l new , said new image marker areas having the same shape and location as image marker areas present in image l n but not in image l n-1 , and said new image marker areas being identifiable in l new by a unique feature. Further, the application discloses a method for visualizing cell populations in tissue sections of a histological sample. Further, the application discloses a method for visualizing three-dimensional distribution of multiple cell populations in a histological sample.

Abstract translation: 一种用于区分一系列数字图像中的区域的方法，所述方法包括以下步骤：提供包括未确定标记区域的一系列图像; 根据预定的选择标准评估1 = n = N的每个图像ln，并将图像标记区域定义为满足预定选择标准的未确定标记区域; 提供新的形象; 并且在新图像中插入新的图像标记区域，所述新的图像标记区域具有与图像ln中不存在但不在图像ln-1中的图像标记区域相同的形状和位置，并且所述新图像标记区域可被新鲜图像标识区域识别 一个独特的功能。 此外，该申请公开了一种在组织学样品的组织切片中可视化细胞群的方法。 此外，本申请公开了一种用于在组织学样品中可视化多个细胞群体的三维分布的方法。