Abstract:
PROBLEM TO BE SOLVED: To provide a device for focusing and accumulating ions which can focus ions on a small diameter as much as possible, and separates two pressure regions suitably. SOLUTION: The invention relates to the device 1301 for focusing and accumulating ions and a device for separating a first pressure region from a second pressure region, especially relates to an ion analyzer 1400. A particle beam device includes at least one of the above devices, and includes a container 1201 for housing ions, and at least one multipole unit 1301. The multipole unit 1301 includes a through port 1302 having a longitudinal axial line 1307, and includes a plurality of electrodes. A first group of these electrodes is at a first radial distance from the longitudinal axial line 1307. A second group of these electrodes is at a second radial distance from the longitudinal axial line 1307 respectively. The first radial distance is smaller than the second radial distance. COPYRIGHT: (C)2011,JPO&INPIT
Abstract:
A method is disclosed comprising applying a reversal agent, such as urea, to a formalin fixed tissue sample in order to reverse the effects of the fixation process. An ambient ionisation ion source such as a desorption electrospray ionisation ("DESI") ion source is used to generate analyte or analyte ions from multiple regions of the modified target so that an ion image of the modified target may be generated.
Abstract:
An apparatus for mass spectrometry and/or ion mobility spectrometry is disclosed comprising a first device (31) arranged and adapted to generate aerosol, smoke or vapour from a target and one or more second devices (34,35) arranged and adapted to aspirate aerosol, smoke, vapour and/or liquid to or towards an analyser (33). A liquid trap or separator (32) is provided to capture and/or discard liquid aspirated by the one or more second devices (34,35).
Abstract:
An apparatus for performing ambient ionisation mass and/or ion mobility spectrometry is disclosed. The apparatus comprises a substantially cylindrical, tubular, rod-shaped,coil- shaped, helical or spiral-shaped collision assembly; and a first device arranged and adapted to direct analyte, smoke, fumes, liquid, gas, surgical smoke, aerosol or vapour onto said collision assembly.
Abstract:
Certain embodiments described herein are directed to collision cells that comprise one or more integrated lenses. In some examples, a lens is coupled to two sections of a sectioned quadrature rod assembly, the lens comprising an aperture and a plurality of separate conductive elements disposed each one side of the lens, in which a respective disposed conductive element on one side of the lens is configured to electrically couple to a first, second, third, and fourth pole segments of the sectioned quadrature rod assembly.
Abstract:
A sample plate (1) for an ion source is disclosed comprising a plurality of ionisation regions, each ionisation region comprising a first electrode (4) and a second separate electrode (4) separated by an insulator (4a).
Abstract:
Certain embodiments described herein are directed to devices that can be used to align the components of a source assembly in a source housing. In some examples, a terminal lens configured to couple to the housing through respective alignment features can be used to retain the source components in a source housing to provide a source assembly.
Abstract:
Embodiments of systems, devices, and methods relate to an electrode standoff isolator. An example electrode standoff isolator includes a plurality of adjacent insulative segments positioned between a proximal end and a distal end of the electrode standoff isolator. A geometry of the adjacent insulative is configured to guard a surface area of the electrode standoff isolator against deposition of a conductive layer of gaseous phase materials from a filament of an ion source.