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公开(公告)号：KR101414040B1
公开(公告)日：2014-07-16
申请号：KR1020120151374
申请日：2012-12-21
Applicant: 대한민국(농촌진흥청장) , 주식회사 글로벌헬스케어
Inventor： 류강선 , 이희삼 , 강필돈 , 김기영 , 김미자 , 권중무 , 천성남 , 김범수 , 조익성 , 이상환 , 이진영 , 임순희 , 최종길 , 김태완 , 박선국 , 김민선 , 임서정
Abstract: 본 발명은 누에추출물을 유효성분으로 하는 혈당조절용 약학 조성물, 천연물의약품 및 건강기능식품에 관한 것이다.
본 발명의 혈당조절용 약학 조성물은 5령3일의 연녹잠 누에로부터 추출한 추출물을 포함하며, 상기 추출물은 에탄올을 용매로 추출한 것을 특징으로 하는 유효성분을 포함하는 것이 특징이다.
본 발명에 따른 누에 추출물의 약학 조성물 및 이를 포함하는 혈당조절용 천연물의약품, 건강기능식품은 혈당조절능이 높은 제조방법 및 용량을 명확히 함으로써, 그로 인해 도출될 수 있는 약효가 종래의 누에분말보다 우수하며, 이와 더불어 종래의 양잠산물에 국한되지 않고, 고부가가치 상품으로 개발이 가능하기 때문에, 양잠농가의 소득증대에 유용하다.-
公开(公告)号：KR101413103B1
公开(公告)日：2014-07-02
申请号：KR1020120138675
申请日：2012-12-03
Applicant: 대한민국(농촌진흥청장)
IPC: C12M1/34 , C12Q1/04 , C12Q1/68 , C12N15/115
Abstract: 세균의 검출 여부를 시각적으로 표시하는 세균 검출 키트; 상기 세균 검출 키트를 수용하는 수용 영역 및 상기 수용 영역과 마주 보는 위치에 형성된 개구부를 포함하는 하우징, 상기 수용 영역에 수용된 상기 세균 검출 키트에 빛을 조사하는 광원부, 및 상기 개구부에 설치된 확대용 렌즈를 포함하는 휴대용 세균 검출 보조 장치; 및 상기 휴대용 세균 검출 보조 장치의 상기 확대용 렌즈를 통해 확대된 상기 검출키트를 촬상하는 촬상 유닛, 저장 유닛, 및 상기 촬상 유닛에 의해 촬상된 상기 검출 키트의 영상정보를 판독하여 세균의 검출 여부를 판단하는 연산 유닛을 포함하는 휴대용 세균 검출 키트 판독 단말기를 포함하는 세균 검출 시스템이 개시된다.
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公开(公告)号：KR1020140048379A
公开(公告)日：2014-04-24
申请号：KR1020120112845
申请日：2012-10-11
Applicant: 대한민국(농촌진흥청장)
CPC classification number: C12Q1/686 , C12Q2525/151
Abstract: The present invention relates to an identifying method of Cordyceps militaris using a PCR method; a primer used for the method; and a Cordyceps militaris identifying kit including the primer. By using the method of the present invention, a user can accurately and rapidly identify Cordyceps militaris which is not easily identified by the outer appearance, thereby capable of being widely applied for developing various products containing Cordyceps militaris.
Abstract translation: 本发明涉及使用PCR方法鉴定冬虫夏草的方法; 用于该方法的底漆; 和含有引物的冬虫夏草militaris鉴定试剂盒。 通过使用本发明的方法，用户可以准确而快速地鉴定出不易被外观识别的冬虫夏草，从而可广泛应用于开发含有冬虫夏草的各种产品。
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54.发明公开
公开(公告)号：KR1020140034004A
公开(公告)日：2014-03-19
申请号：KR1020120100703
申请日：2012-09-11
Applicant: 대한민국(농촌진흥청장)
IPC: C12Q1/04 , G01N33/569 , G01N33/532 , C07K17/02
CPC classification number: G01N33/532 , G01N33/558 , G01N33/587
Abstract: The present invention relates to a labeling agent for Aflatoxin B1 detection and a kit for Aflatoxin B1 detection comprising the same, and more specifically, to a labeling agent for detecting Aflatoxin B1 of a nanoparticle - Aflatoxin B1 - carrier protein polymer and a kit for Aflatoxin B1 detection comprising the same and consisting of a single detection line. The labeling agent for detecting a nanoparticle - Aflatoxin B1 - carrier protein polymer and the kit for Aflatoxin B1 detection comprising the same induce a competitive binding reaction with antibodies immobilized on the detection line to minimize the deformation of antibodies, thereby maximizing the activating efficiency of antibodies, and are useful for the quantitative and qualitative detection of Aflatoxin B1.
Abstract translation: 本发明涉及黄曲霉毒素B1检测用标签试剂和黄曲霉毒素B1检测用试剂盒，更具体地说涉及用于检测纳米粒子黄曲霉毒素B1-载体蛋白质聚合物的黄曲霉毒素B1和黄曲霉毒素试剂盒 B1检测包括它，由单个检测线组成。 用于检测纳米颗粒 - 黄曲霉毒素B1-载体蛋白质聚合物的标记试剂和用于黄曲霉毒素B1检测的试剂盒包括其中的试剂盒诱导与固定在检测线上的抗体的竞争性结合反应，以使抗体的变形最小化，从而使抗体的活化效率最大化 ，对黄曲霉毒素B1的定性和定性检测有用。
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公开(公告)号：KR1020130049304A
公开(公告)日：2013-05-14
申请号：KR1020110114239
申请日：2011-11-04
Applicant: 대한민국(농촌진흥청장)
IPC: A61K31/7076 , A61K31/70 , A61K36/066 , A61P3/04
CPC classification number: A61K36/068 , A61K31/405 , A61K31/708 , A61K2236/333 , Y10S514/909
Abstract: PURPOSE: A pharmaceutical composition containing a Cordyceps militaris-derived compound for treating obesity is provided to ensure an excellent anti-obesity effect without side effects and toxicity. CONSTITUTION: A pharmaceutical composition for treating obesity contains two or more compounds selected among cordycepin, guanosine, and tryptophan derived from Cordyceps militaris. The compound is prepared by extracting Cordyceps militaris with a solvent and fractioning with butanol. The solvent is prepared by mixing water and ethanol in a volume ratio of 1:1. The composition suppresses differentiation of adipocytes.
Abstract translation: 目的：提供含有用于治疗肥胖症的冬虫夏草衍生化合物的药物组合物，以确保优异的抗肥胖效果而没有副作用和毒性。 构成：用于治疗肥胖症的药物组合物含有选自虫草素，鸟苷和来自冬虫夏草的色氨酸的两种或更多种化合物。 通过用溶剂萃取冬虫夏草并用丁醇分馏来制备化合物。 溶剂通过以1:1的体积比混合水和乙醇来制备。 该组合物抑制脂肪细胞的分化。
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Patent Agency Ranking
公开(公告)号：KR1020120067841A
公开(公告)日：2012-06-26
申请号：KR1020100129459
申请日：2010-12-16
Applicant: 대한민국(농촌진흥청장)
IPC: G01N33/569 , G01N33/52 , G01N21/84
Abstract: PURPOSE: A photo biosensor and a method for detecting food poisoning bacterial using the same are provided to perform antigen-antibody immune response and to easily and quickly measure contamination degree. CONSTITUTION: A method for detecting an antigen using a photo biosensor comprises: a step of attaching an antibody to the inner wall of a micro channel(a); a step of irradiating a laser waveguide with laser(b); a step of injecting a subject material to the inside of the micro channel(c); a step of detecting optical signal generated from the micro channel(d); and a step of measuring the concentration of an antigen in the subject material based on the detected optical signal(e). The antibody responds to Salmonella, O-157, and listeria.
Abstract translation: 目的：提供一种光生物传感器和使用其的食物中毒细菌检测方法，以进行抗原 - 抗体免疫应答并容易且快速地测量污染程度。 构成：使用光生物传感器检测抗原的方法包括：将抗体连接到微通道（a）的内壁的步骤; 用激光照射激光波导的步骤（b）; 将主体材料注入到微通道（c）的内部的步骤; 检测从微通道（d）产生的光信号的步骤; 以及基于检测到的光信号（e）测量被检体材料中的抗原浓度的步骤。 抗体对沙门氏菌，O-157和李斯特菌有反应。
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公开(公告)号：KR1020110111153A
公开(公告)日：2011-10-10
申请号：KR1020100030566
申请日：2010-04-02
Applicant: 대한민국(농촌진흥청장)
Abstract: 본 발명은 상족과정 중에 있는 누에의 건조분말을 활성성분으로 함유하는 남성호르몬 분비 촉진용 조성물에 관한 것으로 본 발명에 따른 조성물은 천연소재를 이용하여 부작용이 없으며 혈액내 테스토스테론의 분비를 촉진시켜 남성의 생식능력을 증진시키는 식품조성물 내지 약제학적 조성물로서 이용될 수 있다.
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公开(公告)号：KR1020100130485A
公开(公告)日：2010-12-13
申请号：KR1020090049208
申请日：2009-06-03
Applicant: 대한민국(농촌진흥청장)
Abstract: PURPOSE: An optical bio-sensor using laser evanescent-field and a portable lab-on-a-chip device comprising the same are provided to enhance detecting sensitivity since the change of the refractive index of evanescent filed or the spectrum variation according to the presence/absence of a target substance of test samples is measured. CONSTITUTION: An optical bio-sensor using laser evanescent-field comprises a micro tube and a laser waveguide. The micro tube is touched with the laser waveguide to generate evanescent field. The change of the refractive index of evanescent filed or the spectrum variation according to the presence/absence of the target substance of the test samples, which pass through the micro tube, is measured.
Abstract translation: 目的：提供一种使用激光渐逝场的光学生物传感器和包含该光学生物传感器的便携式实验室芯片，以提高检测灵敏度，因为根据存在的ev逝场的折射率的变化或光谱变化 /测量样品的目标物质的不存在。 构成：使用激光渐逝场的光学生物传感器包括微管和激光波导。 微管与激光波导接触以产生ev逝场。 测量通过微管的试验样品的目标物质的存在/不存在时，消逝场的折射率的变化或光谱变化。
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公开(公告)号：KR1020090085913A
公开(公告)日：2009-08-10
申请号：KR1020080011842
申请日：2008-02-05
Applicant: 대한민국(농촌진흥청장)
Abstract: An impedance biosensor for detecting Staphylococcus aureus is provided to raise the detection sense of Staphylococcus aureus and shorten the culture time. An impedance biosensor for detecting Staphylococcus aureus comprises micro electrode, capture antibody for Staphylococcus aureus and impedance module. The micro electrode is alternately arranged. The capture antibody of Staphylococcus aureus is fixed on the electrode. The impedance module measures impedance and analyzes comparing frequency. A method for detecting Staphylococcus aureus using the biosensor comprises: a step (S1) of adding reactive inhibitor to analysis test sample; a step (S2) of injecting the sample to the capture antibody on the electrode; a step (S3) of removing bacteria and foreign material which is not combined with the antibody, and a step (S4) of measuring and analyzing the impedance.
Abstract translation: 提供了用于检测金黄色葡萄球菌的阻抗生物传感器，以提高金黄色葡萄球菌的检测意义，缩短培养时间。 用于检测金黄色葡萄球菌的阻抗生物传感器包括微电极，金黄色葡萄球菌的捕获抗体和阻抗模块。 微电极交替排列。 金黄色葡萄球菌的捕获抗体固定在电极上。 阻抗模块测量阻抗并分析比较频率。 使用生物传感器检测金黄色葡萄球菌的方法包括：将反应性抑制剂加入到分析试验样品中的步骤（S1） 将样品注射到电极上的捕获抗体的步骤（S2）; 除去与抗体不结合的细菌和异物的步骤（S3）以及测量和分析阻抗的步骤（S4）。
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公开(公告)号：KR1020090032487A
公开(公告)日：2009-04-01
申请号：KR1020070097789
申请日：2007-09-28
Applicant: 대한민국(농촌진흥청장)
IPC: C12Q1/68
CPC classification number: C12Q1/6869 , C12Q1/686
Abstract: Provided is a method for discriminating domestic silkworm powder from imported silkworm powder through direct base sequencing analysis. Nine introns are used as silkworm discrimination markers. The nine introns indicate A4Intron1, A4Intron2, PTTHIntron3, LCP30Intron3, LCP30Intron4, SPIIntron3, VDPIntron4, FLCIntron3 and XDHIntron3. A method for discriminating domestic silkworm powder using the direct base sequencing analysis comprises the following steps of: extracting a genome DNA from the silkworm powder; offering information about DNA amplification existence or nonexistence in a specific intron region through PCR(polymerase chain reaction); offering information about discriminable intron regions based on species and primer in the regions through the direct base sequencing analysis; and comparing the species in the intron regions using the silkworm discrimination marker.
Abstract translation: 提供了一种通过直接碱基测序分析鉴别家蚕粉与进口蚕粉的方法。 九个内含子用作蚕鉴别标记。 九个内含子表示A4Intron1，A4Intron2，PTTHIntron3，LCP30Intron3，LCP30Intron4，SPIIntron3，VDPIntron4，FLCIntron3和XDHIntron3。 使用直接碱基测序分析鉴别家蚕粉的方法包括以下步骤：从蚕粉中提取基因组DNA; 通过PCR（聚合酶链反应）提供有关DNA扩增存在或不存在于特定内含子区域的信息; 通过直接碱基测序分析，提供区域内基于物种和引物的可区分内含子区域的信息; 并使用家蚕鉴别标记物比较内含子区域中的物种。
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