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公开(公告)号：DE69333230T2
公开(公告)日：2004-08-05
申请号：DE69333230
申请日：1993-03-24
Applicant: ABBOTT LAB
Inventor： CLARK FREDERIC L , CLIFT GILBERT , HENDRICK KENDALL B , KANEWSKE III , LAGOCKI PETER A , MARTIN RICHARD R , MITCHELL JAMES E , MOORE LARRY W , PENNINGTON CHARLES D , WALKER EDNA S , SMITH JANE B , TAYI APPARAO , VAUGHT JAMES A , YOST DAVID A , MERRIAM RICHARD A , WALKER DONNY RAY , MCDOWELL DOUGLAS D , RUMBAUGH WILLIAM A , CLEMENS JOHN M
IPC: B01L3/00 , B01L3/08 , B01L9/06 , B29C45/00 , B67D99/00 , C12M1/34 , G01F23/284 , G01N1/00 , G01N1/14 , G01N1/28 , G01N21/03 , G01N21/25 , G01N33/53 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , G05D23/19 , H01J49/04 , H05B1/02
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公开(公告)号：DE69330785T2
公开(公告)日：2002-06-20
申请号：DE69330785
申请日：1993-03-24
Applicant: ABBOTT LAB
Inventor： SCHMIDT LINDA S , SPRONK ADRIAN M , CLARK FREDERIC L , CLIFT GILBERT , HENDRICK KENDALL B , KANEWSKE III , LAGOCKI PETER A , MITCHELL JAMES E , MARTIN RICHARD R , MOORE LARRY E , PENNINGTON CHARLES D , WALKER EDNA S , SMITH JANE B , TAYI APPARAO , VAUGHT JAMES A , YOST DAVID A
IPC: B01L3/00 , B01L3/08 , B01L9/06 , G01N1/00 , G01N21/25 , G01N33/53 , G01N33/536 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04 , G01N33/02 , G01N33/483
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公开(公告)号：CA2172363A1
公开(公告)日：1995-03-31
申请号：CA2172363
申请日：1994-09-22
Applicant: ABBOTT LAB
Inventor： CLARK FREDERICK L , CLEMENS JOHN M , HANCE ROBERT B , HENDRICK KENDALL B , TAYI APPARAO , KANEWSKE WILLIAM J III , LAGOCKI PETER A , MARTIN RICHARD R , MCDOWELL DOUGLAS D , MERRIAM RICHARD A , MOORE LARRY W , OLEKSAK CARL M , PENNINGTON CHARLES D , RAYMOURE WILLIAM J , RUMBAUGH WILLIAM D , SCHMIDT LINDA S , SCHRIER PAUL R , SMITH B JANE , SPRONK ADRIAN M , WALKER EDNA S , VAUGHT JAMES A , VICKSTROM RICHARD L , WALKER DONNY RAY , WATKINS WILLIAM E III , WINTER GARY E , WOHLFORD ROBERT A , CLIFT GILBERT , CLOONAN KEVIN M , MITCHELL JAMES E , STANTON ALYN K , YOST DAVID A , HILLS DAVID B
IPC: G01N33/483 , B01F11/00 , B01L3/00 , B29C45/00 , G01F23/22 , G01F23/26 , G01N1/00 , G01N21/25 , G01N21/64 , G01N21/76 , G01N21/78 , G01N33/53 , G01N33/542 , G01N33/543 , G01N33/553 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04 , G01N37/00
Abstract: An automated, continuous and random access analytical system, having apparat us and methodology capable of simultaneously performing multiple assays of liquid samples using different assay methodolo gies, and providing continuous and random access while performing a plurality of different assays on the same or different samples during the same time period, is disclosed. A method is a lso disclosed of operating an automated continuous and random access analytical system capable of simultaneously effecting multiple assa ys of a plurality of liquid samples wherein scheduling of various assays of the plurality of liquid samples is followed by creating a u nit dose disposable and separately transferring a first liquid sample and reagents to a reaction vessel without initiation of an assay reacti on sequence, followed by physical transfer of the unit dose disposable to a processing wo rkstation, whereby a mixture of the unit dose disposable reagents and sample are achieved during incubation. The system is capable of performi ng more than one scheduled assay in any order, and assay s where more than such scheduled assays are presented. The automated, continuo us and random access analytical system is also capable o f analyzing the incubated reaction mixtures independently and individually by at least two assay procedures.
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公开(公告)号：CA2613156A1
公开(公告)日：1995-03-30
申请号：CA2613156
申请日：1994-09-22
Applicant: ABBOTT LAB
Inventor： TAYI APPARAO , KANEWSKE WILLIAM J III , VAUGHT JAMES A , YOST DAVID A , HILLS DAVID B , LAGOCKI PETER A , WINTER GARY E , VICKSTROM RICHARD L , STANTON ALYN K , PENNINGTON CHARLES D , RAYMOURE WILLIAM J , MARTIN RICHARD R , OLEKSAK CARL M , MITCHELL JAMES E , SCHMIDT LINDA S , WALKER DONNY RAY , WATKINS WILLIAM E III , HENDRICK KENDALL B , WALKER EDNA S , SPRONK ADRIAN M , WOHLFORD ROBERT A , SMITH JANE B , RUMBAUGH WILLIAM D , MOORE LARRY W , MERRIAM RICHARD A , CLOONAN KEVIN M , SCHRIER PAUL R , CLARK FREDERICK L , CLEMENS JOHN M , MCDOWELL DOUGLAS D , HANCE ROBERT B , CLIFT GILBERT
IPC: G01N33/483 , G01N35/00 , B01F11/00 , B01L3/00 , B29C45/00 , G01F23/22 , G01F23/26 , G01N1/00 , G01N1/44 , G01N21/25 , G01N21/64 , G01N21/76 , G01N21/78 , G01N33/53 , G01N33/542 , G01N33/543 , G01N33/553 , G01N35/02 , G01N35/04 , G01N35/10 , G01N37/00 , H01J49/04
Abstract: The invention discloses an automated liquid level sensing system for detecting the presence of liquid in a container, comprising an electrically conductive and movable probe positioned above said container; a signal source electrically connected to said probe, said signal source capable of energizing said probe thereby causing said probe to transmit said electrical signal at a given frequency; a receiving antenna and means for transferring said received electrical signal from said receiving antenna to an analyzing means; wherein analyzing said received electrical signal includes: (1) means for detecting changes in received signal amplitude, wherein said means for detecting changes in received signal amplitude includes:(a) means for multiplying said received signal by a reference signal, said reference signal having a frequency substantially equal to the frequency of the transmitted signal; and (b) a low pass filter through which is passed said multiplied received signal; and (2) means for measuring rate of change of said change in received signal amplitude; and means connected to said analyzing means for indicating that liquid has been detected. The invention further discloses a method of automatically detecting the presence of liquid in a container using the system of the invention. An automated liquid sensing system for use in a clinical analysis system having a pipettor for dispensing or aspirating liquid in a container, the pipettor being electrically conductive and moveable vertically into the container, using the automated liquid sensing system of the invention further comprising a means electrically connected to the pipettor for applying a RF signal thereto and causing the pipettor to radiate an electromagnetic field, the propagation of which changes when the pipettor contacts the surface of the liquid in the container is further disclosed.
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公开(公告)号：AU3934993A
公开(公告)日：1993-11-08
申请号：AU3934993
申请日：1993-03-24
Applicant: ABBOTT LAB
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Patent Agency Ranking
公开(公告)号：CA2132960A1
公开(公告)日：1993-10-14
申请号：CA2132960
申请日：1993-03-24
Applicant: ABBOTT LAB
Inventor： CLARK FREDERIC L , CLIFT GILBERT , HENDRICK KENDALL B , KANEWSKE WILLIAM J III , LOGOCKI PETER A , MARTIN RICHARD R , MITCHELL JAMES E , MOORE LARRY W , PENNINGTON CHARLES D , WALKER EDNA S , SMITH B JANE , TAYI APPARAO , VAUGHT JAMES A , YOST DAVID A , MERRIAM RICHARD A , WALKER DONNY R , RUMBAUGH WILLIAM , CLEMENS JOHN M
IPC: B01L3/00 , B01L3/08 , B01L9/06 , B29C45/00 , B67D99/00 , C12M1/34 , G01F23/284 , G01N1/00 , G01N1/14 , G01N1/28 , G01N21/03 , G01N21/25 , G01N33/53 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , G05D23/19 , H01J49/04 , H05B1/02
Abstract: 2132960 9320440 PCTABS00027 An automated, continuous and random access analytical system, havin apparatus and methodology capable of simultaneously performing multiple assays of liquid samples using different assay methodologies, and providing continuous and random access while performing a plurality of different assays on the same or different samples during the same time period, is disclosed. A method is also disclosed of operating an automated continuous and random access analytical system capable of simultaneously effecting multiple assays of a plurality of liquid samples wherein scheduling of various assays of the plurality of liquid samples is followed by creating a unit dose disposable and separately transferring a first liquid sample (26), reagents (30) to a reaction vessel (34) without initiation of an assay reaction sequence, followed by physical transfer of the unit dose disposable (34) to a process work station (46), whereby a mixture of the unit dose disposable reagents and sample (34) are achieved during incubation. The system is capable of performing more than one scheduled assay in any order, and assays where more than such scheduled assays are presented. The automated, continuous and random access analytical system is also capable of analyzing the incubated reaction mixtures independently and individually by at least two assay procedures.
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公开(公告)号：CA2129246A1
公开(公告)日：1993-10-14
申请号：CA2129246
申请日：1993-03-24
Applicant: ABBOTT LAB
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公开(公告)号：ES2351337T3
公开(公告)日：2011-02-03
申请号：ES04010960
申请日：1994-09-22
Applicant: ABBOTT LAB
Inventor： TAYI APPARAO , MITCHELL JAMES E , HANCE ROBERT B , WATKINS WILLIAM E III , CLARK FREDERICK L , MCDOWELL DOUGLAS D , RAYMOURE WILLIAM J , HILLS DAVID B , CLIFT GILBERT , STANTON ALYN K , SPRONK ADRIAN M , KANEWSKE WILLIAM J III , MARTIN RICHARD R , VAUGHT JAMES A , OLEKSAK CARL M , HENDRICK KENDALL B , SCHRIER PAUL R , PENNINGTON CHARLES D , MOORE LARRY W , CLEMENS JOHN M , WALKER EDNA S , SMITH JANE B , CLOONAN KEVIN M , WOHLFORD ROBERT A , WALKER DONNY RAY , YOST DAVID A , MERRIAM RICHARD A , SCHMIDT LINDA S , VICKSTROM RICHARD L , LAGOCKI PETER A , WINTER GARY E , RUMBAUGH WILLIAM D
IPC: G01N33/483 , G01N35/02 , B01F11/00 , B01L3/00 , B29C45/00 , G01F23/22 , G01F23/26 , G01N1/00 , G01N21/25 , G01N21/64 , G01N21/76 , G01N21/78 , G01N33/53 , G01N33/542 , G01N33/543 , G01N33/553 , G01N35/00 , G01N35/04 , G01N35/10 , H01J49/04
Abstract: Un método para realizar simultáneamente al menos dos análisis, comprendiendo dichos análisis una pluralidad de actividades, para una pluralidad de muestras líquidas en un sistema analítico continuo, comprendiendo dicho método las etapas de: combinar una alícuota de una primera muestra líquida con al menos un reactivo en un primer contenedor de reacción para formar una primera mezcla de reacción de análisis para dicha primera muestra líquida; combinar una alícuota de una segunda muestra líquida con al menos un reactivo en un segundo contenedor de reacción para formar una segunda mezcla de reacción de análisis para dicha segunda muestra líquida; incubar dichas primera y dicha segunda mezcla de reacción de análisis al menos un tiempo; realizar las actividades asociadas con cada análisis distintas de dicha combinación y dicha incubación de la primera y la segunda mezclas de reacción de análisis para completar cada análisis, incluyendo dichas otras actividades analizar las mezclas de reacción de análisis incubadas; y programar las etapas de dicha combinación, dicha incubación, y dichas actividades de realización distintas de dicha combinación y dicha incubación asociadas con cada uno de los análisis de acuerdo con un protocolo predeterminado, especificando dicho protocolo: (a) qué actividades se van a realizar para un análisis dado; (b) el orden en el que se van a realizar dichas actividades de (a); (c) al menos un período de incubación entre dichas actividades de (a), comprendiendo dicho al menos un período de incubación un período nominal de tiempo para la realización de una etapa de incubación entre las actividades de (a) y una ventana de tiempo especificada para añadirla o restarla al período de incubación nominal para variar la duración del período nominal entre las actividades de (a) para optimizar el funcionamiento; (d) cómo se van a realizar dichas actividades de (a); y (e) la duración de dichas actividades de (a).
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公开(公告)号：DE69434702D1
公开(公告)日：2006-05-24
申请号：DE69434702
申请日：1994-09-22
Applicant: ABBOTT LAB
Inventor： CLARK FREDERICK L , CLEMENS JOHN M , HANCE ROBERT B , HENDRICK KENDALL B , TAYI APPARAO , KANEWSKE WILLIAM J III , LAGOCKI PETER A , MARTIN RICHARD R , MCDOWELL DOUGLAS D , MERRIAM RICHARD A , MOORE LARRY W , OLEKSAK CARL M , PENNINGTON CHARLES D , RAYMOURE WILLIAM J , RUMBAUGH WILLIAM D , SCHMIDT LINDA S , SCHRIER PAUL R , SMITH B JANE , SPRONK ADRIAN M , WALKER EDNA S , VAUGHT JAMES A , VICKSTROM RICHARD L , WALKER DONNY RAY , WATKINS WILLIAM E III , WINTER GARY E , WOHLFORD ROBERT A , CLIFT GILBERT , CLOONAN KEVIN M , MITCHELL JAMES E , STANTON ALYN K , YOST DAVID A , HILLS DAVID B
IPC: G01N33/483 , G01N35/10 , B01F11/00 , B01L3/00 , B29C45/00 , G01F23/22 , G01F23/26 , G01F23/284 , G01N1/00 , G01N21/25 , G01N21/64 , G01N21/76 , G01N21/78 , G01N33/53 , G01N33/542 , G01N33/543 , G01N33/553 , G01N35/00 , G01N35/02 , G01N35/04 , H01J49/04
Abstract: The invention relates to an automated liquid level sensing system for detecting the presence of liquid in a container, said liquid level sensing system comprising: a vertically oriented, electrically conductive probe positioned above said container; means for vertically moving said probe into and out of said container; a signal source electrically connected to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; a receiving antenna positioned below said container for receiving said transmitted electrical signal; means for analyzing said received electrical signal for indications that said probe has contacted liquid in said container; means for transferring said received electrical signal from said receiving antenna to said analyzing means; and means for indicating that liquid has been detected. Further, the invention also provides for a method for automatically detecting the presence of liquid in a container, said method comprising the steps of: vertically positioning an electrically conductive probe above said container; vertically moving said probe into and out of said container; electrically connecting a signal source to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; positioning a receiving antenna below said container for receiving said transmitted electrical signal; analyzing said received electrical signal for indications that said probe has contacted liquid in said container; transferring said received electrical signal from said receiving antenna to said analyzing means; and indicating that liquid has been detected.
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公开(公告)号：DE69434638D1
公开(公告)日：2006-04-27
申请号：DE69434638
申请日：1994-09-22
Applicant: ABBOTT LAB
Inventor： CLARK FREDERICK L , CLEMENS JOHN M , HANCE ROBERT B , HENDRICK KENDALL B , TAYI APPARAO , KANEWSKE WILLIAM J III , LAGOCKI PETER A , MARTIN RICHARD R , MCDOWELL DOUGLAS D , MERRIAM RICHARD A , MOORE LARRY W , OLEKSAK CARL M , PENNINGTON CHARLES D , RAYMOURE WILLIAM J , RUMBAUGH WILLIAM D , SCHMIDT LINDA S , SCHRIER PAUL R , SMITH B JANE , SPRONK ADRIAN M , WALKER EDNA S , VAUGHT JAMES A , VICKSTROM RICHARD L ALGONQUIN , WALKER DONNY RAY , WATKINS WILLIAM E III , WINTER GARY E , WOHLFORD ROBERT A , CLIFT GILBERT , CLOONAN KEVIN M , MITCHELL JAMES E , STANTON ALYN K , YOST DAVID A , HILLS DAVID B
IPC: G01N33/483 , G01N35/02 , B01F11/00 , B01L3/00 , B29C45/00 , G01F23/22 , G01F23/26 , G01N1/00 , G01N21/25 , G01N21/64 , G01N21/76 , G01N21/78 , G01N33/53 , G01N33/542 , G01N33/543 , G01N33/553 , G01N35/00 , G01N35/04 , G01N35/10 , H01J49/04
Abstract: The invention relates to an automated liquid level sensing system for detecting the presence of liquid in a container, said liquid level sensing system comprising: a vertically oriented, electrically conductive probe positioned above said container; means for vertically moving said probe into and out of said container; a signal source electrically connected to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; a receiving antenna positioned below said container for receiving said transmitted electrical signal; means for analyzing said received electrical signal for indications that said probe has contacted liquid in said container; means for transferring said received electrical signal from said receiving antenna to said analyzing means; and means for indicating that liquid has been detected. Further, the invention also provides for a method for automatically detecting the presence of liquid in a container, said method comprising the steps of: vertically positioning an electrically conductive probe above said container; vertically moving said probe into and out of said container; electrically connecting a signal source to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; positioning a receiving antenna below said container for receiving said transmitted electrical signal; analyzing said received electrical signal for indications that said probe has contacted liquid in said container; transferring said received electrical signal from said receiving antenna to said analyzing means; and indicating that liquid has been detected.
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