中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

173 records (took 0.023 seconds)

    51.
    发明专利
    未知

    公开(公告)号：DE58905246D1

    公开(公告)日：1993-09-16

    申请号：DE58905246

    申请日：1989-10-04

    Applicant: BASF AG

    Inventor： FRICKEL FRITZ-FRIEDER DR ,  KUEKENHOEHNER THOMAS DR ,  RENDENBACH-MUELLER BEATRICE DR ,  WEIFENBACH HARALD DR ,  TESCHENDORF HANS-JUERGEN DR

    IPC: A61K31/335 ,  A61K31/35 ,  A61K31/40 ,  A61K31/41 ,  A61K31/44 ,  A61K31/443 ,  A61K31/4433 ,  A61K31/445 ,  A61K31/47 ,  A61P25/00 ,  C07D405/12 ,  C07D407/12 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  C07D419/12

    Abstract: Heterocyclically substituted alkoxycoumarins of the formula in which R and R are, independently of one another, hydrogen, C1- to C5-alkyl, trifluoromethyl, phenyl, halogen or together are a C3- to C5-alkylene chain; furthermore R is C1- to C5-alkyl or halogen; n is an integer from 0 to 3; R is hydrogen or C1- to C4-alkyl and Het is one of the following heterocycles: with the following meanings for the symbols used: X is oxygen or sulphur; R is optionally C1-C4-alkoxy-substituted C1-C10-alkyl, 5-6-membered oxacycloalkyl, C3-C7-cycloalkyl, benzyl, an optionally halogen- or NO2-substituted phenyl radical, a pyridine ring, C1-C5-alkoxycarbonyl, perfluoro-C1-C2-alkyl; R is C1-C5-alkyl, C1-C5-alkoxy; R is C1-C5-alkyl, an optionally halogen-substituted benzyl radical, halogen; m is 0 to 2; R is C1-C5-alkyl, C3-C6-cycloalkyl, benzyl, phenyl; R is hydrogen, C1-C4-alkyl; R is C1-C5-alkyl, C3-C6-cycloalkyl; R is C1-C5-alkyl; R is hydrogen, C1-C5-alkyl, C3-C6-cycloalkyl; R is C1-C5-alkyl, halogen, p = 0 to 2; R is C1-C5-alkyl, q = 0 or 1; R , R are hydrogen, C1-C5-alkyl, benzyl; R is hydrogen, C1-C5-alkyl; R is C1-C5-alkyl with the proviso that R is not phenyl when X is oxygen, R is methyl and R to R are hydrogen, method for their preparation and medicaments prepared therefrom.

    55.
    发明专利
    未知

    公开(公告)号：DE3869335D1

    公开(公告)日：1992-04-23

    申请号：DE3869335

    申请日：1988-11-11

    Applicant: BASF AG

    Inventor： KUEKENHOEHNER THOMAS DR ,  GOETZ NORBERT DR ,  THEOBALD HANS DR ,  KNAUS GUENTER H DR

    IPC: C07D213/48 ,  C07D213/50 ,  C07D239/26 ,  C07D261/08

    Abstract: Prodn. of heteroaromatic aldehydes or ketones of formula R-CO-R1 (I) is effected by oxidising the corresp. 1-hydroxyalkyl cpds. of formula R-C(OH)H-R1 (II) with an (in)organic hypochlorite or hypobromite in the presence of an oxidised tetraalkyl cyclic amine (III): R=5 or 6-membered heteroaryl contg. N atom R1=H or 1-20C alkyl. (III) is of formula (III): A1-A4=1-4C alkyl; Q=a gp. of formula Q1-Q3= X=an anion; n=0 or 1; Y=O, CO or CR2R3; R2 and R3=H, OH, or C- or O-bonded organic gps. opt. linked to form a 5- or 6-membered ring. Pref. R=opt. substd. isoxazolyl, pyridyl or pyrimidinyl.

    56.
    发明专利
    未知

    公开(公告)号：DE4009028A1

    公开(公告)日：1991-09-26

    申请号：DE4009028

    申请日：1990-03-21

    Applicant: BASF AG

    Inventor： KUEKENHOEHNER THOMAS DR ,  MAYWALD VOLKER DR

    IPC: C07D261/18

    Abstract: Preparation of isoxazole-4,5-dicarboxylic diesters of the general formula I in which R is any desired organic radical which is inert under the reaction conditions and in which R and R each represent an alkyl, cycloalkyl or benzyl group, characterised in that an aldoxime of the general formula II is reacted with a maleic or fumaric diester of the general formula III R OOC-C=C-COOR (III), in which R and R are identical or different and have the abovementioned meaning, in the presence of an aqueous solution of a hypohalite, in which the hypohalite is present in excess, relative to II.

Patent Agency Ranking