公开(公告)号：JPH08301807A

公开(公告)日：1996-11-19

申请号：JP11283995

申请日：1995-05-11

Applicant: KAO CORP

Inventor： KITA KATSUMI ,  HASHIZUME NAOMICHI

IPC: C07C41/16 ,  C07C41/26 ,  C07C43/13 ,  C07C43/178

Abstract: PURPOSE: To efficiently produce an etherified polyhydric alcohol which is useful as a base for cosmetics using fatty acid polyhydric alcohol esters as a starting substance in increased productivity. CONSTITUTION: (A) A fatty acid polyhydric alcohol ester of the formula: G(B)Z (G is the residual group of a polyhydric alcohol after hydrogen atoms are removed from the hydroxyl groups in a polyhydric alcohol having 3 or more hydroxyl groups; B is H or 1-11C acyl group; Z is the number of hydroxyl groups of the polyhydric alcohol in G; Bs of z number have each at least one of H and an acyl group) and (B) an alkyl halide of RX (R is a 1-36C alkyl, alkenyl) are allowed to react in the presence of a base to give (C) a fatty acid ester of etherified polyhydric alcohol of the formula: G(R)x (B)y (x, y are a number of >=1 totaling to z). Then, the product is hydrolyzed to give the objective alcohol of the formula: C(Rx )Hy.

公开(公告)号：JPH08245534A

公开(公告)日：1996-09-24

申请号：JP5535895

申请日：1995-03-15

Applicant: KAO CORP

Inventor： HASHIZUME NAOMICHI ,  KAMIYA HIROSHI ,  KITA KATSUMI

IPC: A61K8/30 ,  A61K8/00 ,  A61K8/42 ,  A61K8/60 ,  A61K8/73 ,  A61Q5/12 ,  C07C231/02 ,  C07C233/18 ,  A61K7/08

Abstract: PURPOSE: To obtain a new branched fatty acid amide forming a thermotropic liquid crystal in a water dispersion system, showing compatibility with almost all solvents, having excellent dispersibility and useful a cosmetic base, etc. CONSTITUTION: This compound is shown by formula I [A is a group of formula II or formula III ((p) and (q) are each 0-14 to give the total of 0-14; (r) and (s) are each 0-13 to give the total of 0-13) ; B is a residue derived from a polyhydric alcohol containing three or more hydroxyl groups by removal of one hydroxyl group; R is H or a 1-6C alkyl] such as N (2,3,4,5,6- pentahydroxyhexyl)-isostearic acid amide. The compound of formula I is obtained by reacting a branched fatty acid derivative of formula IV (X is a halogen, hydroxyl or methoxyl) with a polyolamine of formula V.

公开(公告)号：JPH08208548A

公开(公告)日：1996-08-13

申请号：JP1504495

申请日：1995-02-01

Applicant: KAO CORP

Inventor： FUJII YASUYUKI ,  FURUGAKI HISAKAZU ,  KITA KATSUMI

IPC: A61K8/30 ,  A61K8/00 ,  A61Q19/00 ,  C07C41/03 ,  C07C41/16 ,  C07C43/10 ,  C07C43/13 ,  C07C43/15 ,  C07C43/178 ,  C07C43/184 ,  C07C43/196 ,  A61K7/00 ,  A61K7/48

Abstract: PURPOSE: To simply obtain a glycerol triether useful as a cosmetic oil, having slight stickiness and excellent in touch by reacting a diether derivative of glycerol with an alkenyl halide and then hydrogenating the resultant reactional product. CONSTITUTION: A 1,3-diether derivative of glycerol of formula I (R1 is a 1-24C alkyl, alkenyl or cyclic alkyl) is reacted with an alkenyl halide of formula II (R2 is H, a 1-7C alkyl; R3 is H or methyl; X is a halogen) [preferably (meth) allyl chloride] and the resultant reactional product is then hydrogenated to afford the objective compound of formula III.

公开(公告)号：JPH08165348A

公开(公告)日：1996-06-25

申请号：JP30867694

申请日：1994-12-13

Applicant: KAO CORP

Inventor： IHARA TAKESHI ,  YANO SHINJI ,  KITA KATSUMI

IPC: A61K8/72 ,  A61K8/89 ,  A61Q1/00 ,  A61Q1/12 ,  C08G77/28 ,  C08G77/395 ,  C08L83/08 ,  A61K7/00

Abstract: PURPOSE: To obtain an emulsifier which stably emulsifies a silicone oil for cosmetics and give cosmetics excellent in the feeling in use. CONSTITUTION: An organo(poly)siloxane having at least one hydrogen atom bonded to a silicon atom is reacted with a polyaluminum salt of a terminally unsatd. phosphoric diester represented by formula I (wherein R is 2-20C linear or branched alkylene; R is an optionally alkylated 1-50C linear or branched group; p is 0-200; M is a polyhydroxoaquaaluminum ion; and n is the valence of M) to give an organo(poly)siloxane modified with a polyaluminum salt of a phosphoric diester represented by formula II (wherein R , R , p, M, and n are each the same as in formula I) having a divalent residue formed from the polyaluminum salt. The modified organo(poly)siloxane is added in an amt. of 0.01-30-wt.% to a silicone oil to emulsify it to produce cosmetics.

公开(公告)号：JPH0827080A

公开(公告)日：1996-01-30

申请号：JP15755494

申请日：1994-07-08

Applicant: KAO CORP

Inventor： UNO MITSURU ,  KITSUKI TOMOHITO ,  KITA KATSUMI

IPC: C07D303/36 ,  A61K8/00 ,  A61K8/40 ,  A61K8/41 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q19/10 ,  C07C229/12 ,  C07C229/16 ,  C07C309/14 ,  C07C309/17 ,  C11D1/88 ,  A61K7/075 ,  A61K7/50

Abstract: PURPOSE:To obtain the new amine compound little in the irritation of skin, excellent in foamability, washability and touch, and useful as a skin cosmetic base agent, a washing agent, an emulsifier, a wetting agent, a conditioning agent, etc. CONSTITUTION:This compound is expressed by formula I [R ,R are (OH- substituted) 1-24C (branched)alkyl, (OH-substituted) 1-24c (branched)alkenylene; A is (OH-substituted) 1-6C (branched)alkylene; Y is carboxyl, sulfonic acid group; Z is sulfoalkyl, amino acid (salt) group from which an NH2 is removed], its salt or quaternary salt, for example, 11,15-dihydroxy-9,13,17-triaza-9,13,17- tricarboxymethylpentacosane. The compound of formula I is obtained by reacting a compound of formula II with a compound of formula III (X is halogen).

公开(公告)号：JPH07188263A

公开(公告)日：1995-07-25

申请号：JP32760093

申请日：1993-12-24

Applicant: KAO CORP

Inventor： OKUTSU TAKAHISA ,  YANO SHINJI ,  KITA KATSUMI ,  FUJIKURA YOSHIAKI

IPC: A61K8/00 ,  A61Q1/00 ,  A61Q1/12 ,  A61Q17/04 ,  C07F9/09 ,  C09K3/00 ,  A61K7/42

Abstract: PURPOSE:To obtain the subject ester expressed by a specific formula, highly safe to the skin, useful as e.g. a highly sustainable ultraviolet light absorber with high remainability on the skin to be formulated in cosmetics. CONSTITUTION:This ester is expressed by formula I (R is an acyl having at least one benzene ring; R is a -12C alkylene where 0 atom(s) may be put between C atoms adjacent to each other; M is a divalent or higher valent metallic ion; (m) is (n)/2; (n) is the valence of the M), e.g. a compound of formula II. This ester can be preferably obtained, for example, by the following processes: a carboxylic acid corresponding to R is monoesterified with a diol corresponding to R , and the resultant monoester is phosphorylated by phosphorus oxychloride followed by neutralization or salt interchange.

公开(公告)号：JPH0761990A

公开(公告)日：1995-03-07

申请号：JP5708494

申请日：1994-03-28

Applicant: KAO CORP

Inventor： YANO SHINJI ,  OKUTSU TAKAHISA ,  KITA KATSUMI ,  FUJIKURA YOSHIAKI ,  FUKAZAWA JUNICHI

IPC: A61K8/00 ,  A61K8/92 ,  A61Q1/00 ,  A61Q1/12 ,  A61Q17/04 ,  C07F9/09 ,  C09K3/00 ,  A61K7/42

Abstract: PURPOSE:To obtain a new phosphoric acid diester useful as an effective component for sun protection cosmetics, being highly safe for skin and having UV preventing effect with high remaining ability and excellent persistency on skin. CONSTITUTION:A phosphoric acid diester of the formula I[R1 is at least an acyl having 1 benzene ring (preferably p-methoxycinnamoyl, etc.); R2 is a 2-12C alkylene; L is a 2-40C alkyl or a R1-O-R2 group; M is H or an alkali metal ion, etc.; n is valence of M]. E.g. a compound of the formula II, etc. The compound of the formula I is obtained, e.g. by reacting a carboxylic acid having at least 1 benzene ring with a diol having 2-12C alkylene to obtain a monoester derivative, which is reacted with phosphorus oxychloride and then salt-exchanged or neutralized.

公开(公告)号：JPH06247990A

公开(公告)日：1994-09-06

申请号：JP24126493

申请日：1993-09-28

Applicant: KAO CORP

Inventor： YANO SHINJI ,  OKUTSU TAKAHISA ,  KITA KATSUMI ,  FUJIKURA YOSHIAKI

IPC: C07F9/09 ,  C09K3/00

Abstract: PURPOSE:To obtain the subject new compound polyvalent metal salt useful as a gelatinizing agent for a wide range of oil agents including silicone oils, excellent in oil gelatinizing ability by reacting a phosphoric diester or its salt with a specific polyvalent metal salt. CONSTITUTION:A phosphoric diester of formula I (R is 1-20C alkyl; R and R are 2-3C alkylene; R is 3-20C alkylene; A is COO or O; (x) and (y) are 0-10 integers; L is 1-40C alkyl or group of formula II; X is H, alkali metal, ammonium, alkylamine or alkanolamine) or its salt is reacted with a polyvalent metal salt of the formula Mpyq (M is di- or polyvalent metal ion; Y is organic or inorganic anion; (p) is integer corresponding to valence the of Y and (q) is integer corresponding to valence of M and both are the minimal integers) (e.g. aluminum acetate) to give a new phosphoric diester polyvalent metal salt of the formula III ((m) is the same number as that of the valence of polyvalent metal ion) useful as a gelatinizing agent for oil agents.

公开(公告)号：JPH06136128A

公开(公告)日：1994-05-17

申请号：JP16480893

申请日：1993-07-02

Applicant: KAO CORP

Inventor： IHARA TAKESHI ,  YANO SHINJI ,  KITA KATSUMI ,  FUJIKURA YOSHIAKI

IPC: A61K8/72 ,  A61K8/00 ,  A61K8/06 ,  A61K8/89 ,  A61Q5/00 ,  A61Q19/00 ,  C08G77/38 ,  C08G77/395 ,  C08L83/08 ,  A61K7/00 ,  A61K7/06 ,  A61K7/48

Abstract: PURPOSE:To obtain a modified organo(poly)siloxane useful as an ingredient of cosmetics by reacting a specific alcohol-modified organo(poly)siloxane with a phosphorus oxyhalide and hydrolyzing the linkage between phosphorus and a halogen. CONSTITUTION:An alcohol-modified organo(poly)siloxane having at least one group of formula I (wherein R and R are each 2-4C alkylene; R is a 1-50C linear or branched alkylene group optionally having hydroxyl groups; q is 0-200; and r is 0 or 1) directly attached to an Si atom in the molecular chain is reacted with a phosphorus oxyhalide, and the linkage between phosphorus and a halogen is hydrolyzed, giving an organo(poly)siloxane having at least one group of formula II (wherein R , R , R , q, and r are each the same as described above; and M and M are each H, an alkali metal, ammonium, or an alkylamine or alkanolamine group). Thus obtd. organo(poly)siloxane is excellent in compatibility, emulsifying properties, foaming properties, etc., and suitable as an ingredient of cosmetics.

公开(公告)号：JPH05229923A

公开(公告)日：1993-09-07

申请号：JP3787692

申请日：1992-02-25

Applicant: KAO CORP

Inventor： YAMAGISHI ATSUSHI ,  NAKAI RYOZO ,  KAMIYA HIROSHI ,  KITA KATSUMI

IPC: A61K8/00 ,  A61Q11/00

Abstract: PURPOSE:To provide an oral cavity composition having a good smell, a good taste, not changing the tastes of beverages and foods, having excellent foamability, minimized in irritative, having good cerumen dispersibility, and not inhibiting the actions of pharniacologically active agents such as bactericides and antiseptics. CONSTITUTION:A glyceryl-etherized polyhydric alcohol of the formula (R is the residue of a polyhydric alcohol, saccharide alcohol or saccharide having four or more OH groups; R is 4-20C linear or branched alkyl or alkenyl) is added preferably in an amount of 0.1-20wt.%, especially 0.5-5wt.%, based on the whole composition as an essential component to an oral cavity composition such as tooth paste, tooth powder, tooth liquid, mouth wash, gargling tablet gingiva-massaging cream, chewing gum, troche or candy to afford an oral cavity composition having the above-mentioned activities. The composition can be used together with a cationic bactericide because it does not inhibit the actions of pharmacologically active agents.