公开(公告)号：DE59710481D1

公开(公告)日：2003-10-02

申请号：DE59710481

申请日：1997-12-23

Applicant: LEICA MICROSYSTEMS

Inventor： ULRICH HEINRICH ,  ENGELHARDT JOHANN

IPC: G02B21/00 ,  G02B27/64

Abstract: The invention relates to a microscope, in particular a confocal microscope, designed to measure an object from several angular positions while avoiding any rotation of the object to be measured. The microscope has an optical device for rotation of the image to be positioned in the ray path of the microscope.

公开(公告)号：DE59905452D1

公开(公告)日：2003-06-18

申请号：DE59905452

申请日：1999-02-17

Applicant: LEICA MICROSYSTEMS

Inventor： ENGELHARDT JOHANN

IPC: G02B7/16 ,  G02B21/24 ,  G02B21/30

Abstract: A microscope with an objective turret (2) carrying an objective (1) and with a specimen holder (4) serving to receive a specimen (3), in order to assure an undesired transport of heat between the specimen (3) and the objective (1), is characterized by the fact that all objectives (1) carried by the objective turret (2) are simultaneously adjusted for temperature by means of the objective turret (2).

公开(公告)号：GB2369953B

公开(公告)日：2003-04-30

申请号：GB0123899

申请日：2001-10-04

Applicant: LEICA MICROSYSTEMS

Inventor： ENGELHARDT JOHANN ,  HOFFMANN JUERGEN

IPC: G02B21/06 ,  G02B21/00 ,  G02B21/16

Abstract: A light source for illumination in scanning microscopy, and a scanning microscope contain an electromagnetic energy source that emits light of one wavelength, and a beam splitter for spatially dividing the light into at least two partial light beams. An intermediate element for wavelength modification is provided in at least one partial light beam.

公开(公告)号：GB2366115B

公开(公告)日：2003-04-02

申请号：GB0117156

申请日：2001-07-13

Applicant: LEICA MICROSYSTEMS

Inventor： ENGELHARDT JOHANN ,  HOFFMANN JUERGEN

IPC: G02B21/06 ,  G02B21/00 ,  G02B21/08 ,  G02B27/28

公开(公告)号：DE10126286A1

公开(公告)日：2002-12-19

申请号：DE10126286

申请日：2001-05-30

Applicant: LEICA MICROSYSTEMS

Inventor： ENGELHARDT JOHANN ,  WIDZGOWSKI BERND

IPC: G02B21/00 ,  G02B21/16 ,  G02B26/10 ,  H04N1/113

Abstract: A method and an apparatus for point-by-point scanning of a specimen ( 15 ) are disclosed. The method is characterized by the steps of generation ( 45 ) of a nominal signal ( 10 ) for each scan point and transfer ( 47 ) of the nominal signal to a scanning device ( 7 ). In further steps, determination ( 49 ) of an actual signal ( 25 ) for each scan point from the setting of the scanning device ( 7 ), detection ( 51 ) of at least one detection signal ( 21 ) for each scan point, calculation ( 53 ) of a display signal ( 27 ) and an image point position ( 29 ) from the actual signal ( 25 ) and/or the nominal signal ( 10 ) and the detection signal ( 21 ), and assignment ( 55 ) of the display signal ( 27 ) to the image point position ( 29 ), are performed.

公开(公告)号：DE10111825A1

公开(公告)日：2002-09-26

申请号：DE10111825

申请日：2001-03-13

Applicant: LEICA MICROSYSTEMS

Inventor： BIRK HOLGER ,  ENGELHARDT JOHANN

IPC: G02B7/00 ,  G02B21/00

Abstract: Method for aligning a light beam in an optical system in which the light beam is coupled into the optical alignment system; the resulting coupled beam is deflected towards at least two photodetectors (10, 22) each at different distances from the beam coupling position (3); calculation of the difference between actual and design position of the coupled beam and adjustment of an optical element to bring the coupled beam into its design position. An Independent claim is made for a device for alignment of a light beam in an optical system.

公开(公告)号：DE10056384A1

公开(公告)日：2002-05-29

申请号：DE10056384

申请日：2000-11-14

Applicant: LEICA MICROSYSTEMS

Inventor： ENGELHARDT JOHANN

IPC: G01N21/64 ,  G02B21/16 ,  G01N21/63

Abstract: An apparatus for measuring the lifetime of an excited state in a specimen is disclosed. The apparatus comprises an electromagnetic energy source ( 1 ) that emits light ( 3 ) of one wavelength. Also provided are a means ( 5 ) for dividing the light ( 3 ) into at least a first and a second partial light beam ( 7, 9 ) and an intermediate element ( 23 ) in at least one partial light beam to influence the transit time.

公开(公告)号：DE59901063D1

公开(公告)日：2002-05-16

申请号：DE59901063

申请日：1999-01-28

Applicant: LEICA MICROSYSTEMS

Inventor： ENGELHARDT JOHANN

IPC: G01J3/14 ,  G01J3/18 ,  G01J3/36 ,  G02B21/00

Abstract: An apparatus for simultaneous detection of a plurality of spectral regions of a light beam (1), in particular for detection of the light beam (1) of a laser scanner (2) in the detection beam path of a confocal microscope, is characterized, in order to achieve a simple configuration with small overall size and elimination of the defocusing effect, by an arrangement (3) for spectral spreading of the light beam (1) and an arrangement (4) for splitting the spread beam (5) out of the dispersion plane (6) into spectral regions (7, 8, 9), and for subsequent detection of the split spectral regions (7, 8, 9).

公开(公告)号：GB2367702A

公开(公告)日：2002-04-10

申请号：GB0118351

申请日：2001-07-27

Applicant: LEICA MICROSYSTEMS

Inventor： ENGELHARDT JOHANN ,  HOFFMANN JUERGEN

IPC: G02B5/10 ,  G02B7/198 ,  G02B21/00 ,  G02B21/06 ,  G02B26/10

Abstract: A scanning microscope, in particular a confocal scanning microscope, with a light source (1), preferably a laser, for generating an illumination light beam (14) for a sample (11) and a scanning device for deflecting the illumination light beam (14) is, with a view to fast and reliable image-data acquisition and a compact structure, configured and refined in such a way that the scanning device has at least one micromirror (16). An optical arrangement with a light source (1), preferably a laser, for generating a light beam and at least one micromirror (16) for deflecting the light beam is furthermore provided, in which an adaptive lens (22) is provided for correcting for mirror defects or deformation of the mirror surface. Lastly, a method for imaging in scanning microscopy, in particular in confocal scanning microscopy, with a light source (1), preferably a laser, for generating an illumination light beam (14) for a sample (11) and a scanning device for deflecting the illumination light beam (14) is provided, in which at least one micromirror (16) is used in the scope of the scanning device.

公开(公告)号：DE10044636A1

公开(公告)日：2002-03-21

申请号：DE10044636

申请日：2000-09-08

Applicant: LEICA MICROSYSTEMS

Inventor： ENGELHARDT JOHANN ,  HOFFMANN JUERGEN

IPC: G02B21/00 ,  G02B21/06 ,  H01S3/067 ,  H01S3/17

Abstract: A confocal scanning microscope has an illuminating beam path and at least one light source. The light of the light source is coupled into a fiber in which laser transitions can be induced. At least laser light induced in the fiber serves for specimen illumination after passing through an excitation pinhole.