Culture vessel and microscope for observing sample in culture vessel
    51.
    发明授权
    Culture vessel and microscope for observing sample in culture vessel 有权
    培养容器和显微镜观察培养皿中的样品

    公开(公告)号:US06238911B1

    公开(公告)日:2001-05-29

    申请号:US09340019

    申请日:1999-06-28

    Inventor: Takashi Kasahara

    Abstract: The present invention provides a culture vessel and microscope that allows a wide area of favorable observation of the sample in the plural wells even when a negative refractive power is generated in the culture medium, wherein a ring-shaped opening, a condenser lens, a lens array, a well plate, an objective lens and a phase contrast plate are disposed in this order viewed from the light source side with a construction to place a phase contrast film of the phase contrast plate in a conjugated relation to the projection pupil position or projection pupil of the objective lens, and the culture vessel is constructed of the lens array and well plate with a relative disposition in which the optical axis of each lens is coaxial with the center line of the confronting each well; the aperture of the ring-shaped opening being smaller than the aperture of the ring-shaped opening that is used when the culture vessel is not disposed in the optical path.

    Abstract translation: 本发明提供了一种培养容器和显微镜,即使在培养基中产生负折射力时,也可以在多个孔中对样品进行良好的观察的广泛区域,其中环形开口,聚光透镜,透镜 阵列,阱板,物镜和相位差板以从光源侧观察的顺序设置,以使相位差板的相位相对于投影光瞳位置或投影的共轭关系 物镜的瞳孔,培养容器由透镜阵列和孔板构成,其相对配置为每个透镜的光轴与面对的每个孔的中心线同轴; 环形开口的孔径小于当培养容器未设置在光路中时使用的环形开口的孔。

    SYSTEM AND METHOD FOR MULTIMODE IMAGING
    55.
    发明申请
    SYSTEM AND METHOD FOR MULTIMODE IMAGING 审中-公开
    用于多模式成像的系统和方法

    公开(公告)号:WO2007103642A3

    公开(公告)日:2008-04-10

    申请号:PCT/US2007062667

    申请日:2007-02-23

    Abstract: A system and method for multimode imaging of at least one sample is disclosed. The system includes at least one light source; an optical system selected responsive to a mode of operation of the imaging system; and a detector capable of selective reading of pixels. The at least one sample is moved relative to the optical system using a sample movement technique selected from the group consisting of step sample moving and continuous sample moving. The method includes the steps of (1) selecting a mode of operation for the imaging system; (2) transmitting light from at least one light source through an optical system selected in response to the mode of operation for the imaging system; (3) moving the at least one sample relative to the optical system using a sample movement technique selected from the group consisting of step sample moving and continuous sample moving; and (4) selectively reading pixels with a detector.

    Abstract translation: 公开了一种用于至少一个样品的多模成像的系统和方法。 该系统包括至少一个光源; 响应于成像系统的操作模式选择的光学系统; 以及能够选择性地读取像素的检测器。 使用选自步骤样品移动和连续样品移动的样品移动技术,使至少一个样品相对于光学系统移动。 该方法包括以下步骤:(1)选择成像系统的操作模式; (2)从至少一个光源透射通过响应于成像系统的操作模式选择的光学系统的光; (3)使用选自步骤样品移动和连续样品移动的样本移动技术来移动所述至少一个样品相对于所述光学系统; 和(4)用检测器选择性地读取像素。

    SYSTEM AND METHOD FOR MULTIMODE IMAGING
    56.
    发明申请
    SYSTEM AND METHOD FOR MULTIMODE IMAGING 审中-公开
    用于多模式成像的系统和方法

    公开(公告)号:WO2007103642A2

    公开(公告)日:2007-09-13

    申请号:PCT/US2007/062667

    申请日:2007-02-23

    Abstract: A system and method for multimode imaging of at least one sample is disclosed. The system includes at least one light source; an optical system selected responsive to a mode of operation of the imaging system; and a detector capable of selective reading of pixels. The at least one sample is moved relative to the optical system using a sample movement technique selected from the group consisting of step sample moving and continuous sample moving. The method includes the steps of (1) selecting a mode of operation for the imaging system; (2) transmitting light from at least one light source through an optical system selected in response to the mode of operation for the imaging system; (3) moving the at least one sample relative to the optical system using a sample movement technique selected from the group consisting of step sample moving and continuous sample moving; and (4) selectively reading pixels with a detector.

    Abstract translation: 公开了一种用于至少一个样品的多模成像的系统和方法。 该系统包括至少一个光源; 响应于成像系统的操作模式选择的光学系统; 以及能够选择性地读取像素的检测器。 使用选自步骤样品移动和连续样品移动的样品移动技术,使至少一个样品相对于光学系统移动。 该方法包括以下步骤:(1)选择成像系统的操作模式; (2)从至少一个光源透射通过响应于成像系统的操作模式选择的光学系统的光; (3)使用选自步骤样品移动和连续样品移动的样本移动技术来移动所述至少一个样品相对于所述光学系统; 和(4)用检测器选择性地读取像素。

    MESSGERÄT ZUR LUMINESZENZMESSUNG
    58.
    发明申请
    MESSGERÄT ZUR LUMINESZENZMESSUNG 审中-公开
    压力表适用于测量发光

    公开(公告)号:WO2014040730A1

    公开(公告)日:2014-03-20

    申请号:PCT/EP2013/002732

    申请日:2013-09-11

    Abstract: Die Erfindung betrifft ein Messgerät zur Lumineszenzmessung mit einem Probenträger (8) zur Aufnahme einer lumineszenten Probe (9), einem ersten Linsen-Array (13) mit zahlreichen rasterförmig angeordneten Linsen (14) zur Fokussierung von Lumineszenzstrahlung, die von der lumineszenten Probe (9) ausgeht, sowie mit einem Lichtsensor (16) zur Erfassung der von der lumineszenten Probe (9) emittierten Lumineszenzstrahlung, wobei der Lichtsensor (16) im Strahlengang der Lumineszenzstrahlung hinter dem ersten Linsen-Array (13) angeordnet ist. Es wird vorgeschlagen, dass das erste Linsen-Array (13) ein erstes Mikrolinsen-Array (13) mit zahlreichen Mikrolinsen (14) ist, wobei im Strahlengang der Lumineszenzstrahlung zwi- sehen dem Probenträger (8) und dem ersten Mikrolinsen-Array (13) eine erste Lochmaske (11) mit zahlreichen Löchern (12) angeordnet ist, wobei die einzelnen Mikrolinsen (14) und die Löcher (12) einander zugeordnet sind und übereinstimmende Achsen aufweisen. Der Probenträger (8) kann einen im Wesentlichen planaren Wellenleiter (8) aufweisen, wobei die Anregungsstrahlung von einer Beleuchtungseinheit (1) in eine Wellenleiterkante (10) des Wellenleiters (8) eingekoppelt wird.

    Abstract translation: 本发明涉及一种测量设备,用于以接收的发光试料(9),第一透镜阵列(13)配有许多布置在光栅透镜(14),用于聚焦所述发光辐射,其(从发光试料9,测定的发光与样品托架(8) )延伸,并且与一个光传感器(16),用于检测(发射的光辐射的发光试料9),其中,在所述发光辐射的光束路径中的光传感器(16)位于所述第一透镜阵列(13)的后面的。 它提出,所述第一透镜阵列(13)是具有许多微透镜(14)的第一微透镜阵列(13),见是 - 在发光辐射到样品托架(8)和(第一微透镜列阵13上的光束路径 )第一荫罩(11)配有许多孔(12)布置,所述各个微透镜(14)和孔(12)彼此相关联,并且具有重合的轴线。 所述样品载体(8)可以具有基本上平面的波导(8),其特征在于,从照明单元(1)在所述波导(8)的波导边缘(10)的激发辐射被耦合。

    OPTICAL DETECTION SYSTEM FOR LIQUID SAMPLES
    59.
    发明申请
    OPTICAL DETECTION SYSTEM FOR LIQUID SAMPLES 审中-公开
    液体样品光学检测系统

    公开(公告)号:WO2013186672A3

    公开(公告)日:2014-03-06

    申请号:PCT/IB2013054660

    申请日:2013-06-06

    Abstract: A tip for use in an optical detection system to analyze an analyte in a fluid sample drawn into the tip, using light reflected from a detection surface inside the tip that the analyte binds to, comprising a first detection surface and a second detection surface located in a same flow path with no controllable valve separating them, wherein the first and second detection surfaces have different surface chemistries.

    Abstract translation: 一种用于光学检测系统的尖端,用于使用从分析物结合到所述尖端内部的检测表面反射的光来分析吸入所述尖端的流体样品中的分析物,所述检测表面包括第一检测表面和位于 相同的流动路径,没有可分离它们的可控阀,其中第一和第二检测表面具有不同的表面化学性质。

    MICROSCOPE ARRAY FOR SIMULTANEOUSLY IMAGING MULTIPLE OBJECTS
    60.
    发明申请
    MICROSCOPE ARRAY FOR SIMULTANEOUSLY IMAGING MULTIPLE OBJECTS 审中-公开
    微阵列同时成像多个对象

    公开(公告)号:WO2004005994A1

    公开(公告)日:2004-01-15

    申请号:PCT/US2003/021268

    申请日:2003-07-07

    CPC classification number: G02B21/002 G01N21/253 G01N2201/0407

    Abstract: A microscope array for simultaneously imaging multiple objects. A preferred embodiment of a method according to the invention includes arranging the objects (46) into an array (34), providing a microscope array (32) having a plurality of imaging elements with respective fields of view arranged into a corresponding array (38) such that the imaging elements are optically aligned respectively with the objects, and simultaneously imaging the objects with the microscope array to produce respective images of the objects by means of a detector array (40). The invention also provides for scanning while imaging, and for stepping and repeating the imaging process. The plurality of imaging elements form a lens array.

    Abstract translation: 用于同时成像多个物体的显微镜阵列。 根据本发明的方法的优选实施例包括将物体(46)布置成阵列(34),提供具有多个成像元件的显微镜阵列(32),其具有排列成相应阵列(38)的各个视场, 使得成像元件分别与物体进行光学对准,并且同时用显微镜阵列成像物体以通过检测器阵列(40)产生物体的相应图像。 本发明还提供了成像时的扫描,以及步进和重复成像过程。 多个成像元件形成透镜阵列。

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