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公开(公告)号：KR1020100097855A
公开(公告)日：2010-09-06
申请号：KR1020090016712
申请日：2009-02-27
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/97 , A61K8/44 , A61Q17/04 , A61Q19/08 , Y10S514/844
Abstract: PURPOSE: A cosmetic composition for UV protection and anti-aging is provided to suppress damage to keratinocytes and fibroblasts. CONSTITUTION: A cosmetic composition for UV protection contains 0.00001-1.0 weight% of pfaffia glomerata root juice and 0.00001-1.0 weight% of arginine PCA as active ingredients. The composition is used for suppressing neural cell injury and neurotransmitter secretion. The composition also used for suppressing damage to keratinocytes or fibroblasts.
Abstract translation: 目的：提供用于防紫外线和抗老化的化妆品组合物，以抑制角质形成细胞和成纤维细胞的损伤。 构成：用于紫外线防护的化妆品组合物含有0.00001-1.0重量百分比的巴菲特根霉汁和0.00001-1.0重量％的精氨酸PCA作为活性成分。 该组合物用于抑制神经细胞损伤和神经递质分泌。 该组合物还用于抑制角质形成细胞或成纤维细胞的损伤。
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公开(公告)号：KR1020100060753A
公开(公告)日：2010-06-07
申请号：KR1020080119484
申请日：2008-11-28
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A cosmetic composition for anti-aging is provided to protect skin from metal stress, external stress, and toxic factor and to activate skin cell regeneration. CONSTITUTION: A cosmetic composition for anti-aging contains 0.00001-1.0 weight% of pfaffia glomerata root juice and 0.00001-1.0 weight% of arginine PCA. The composition further contains 0.00001-10 weight% of oleanolic acid, ursolic acid, betacarotene, or retinol.
Abstract translation: 目的：提供抗衰老的化妆品组合物，以保护皮肤免受金属压力，外部压力和毒性因素的影响，并激活皮肤细胞再生。 构成：用于抗衰老的化妆品组合物含有0.001-1-0重量％的巴菲特薄荷根汁和0.00001-1.0重量％的精氨酸PCA。 该组合物还含有0.00001-10重量％的齐墩果酸，熊果酸，β-胡萝卜素或视黄醇。
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公开(公告)号：KR1020090128230A
公开(公告)日：2009-12-15
申请号：KR1020080054295
申请日：2008-06-10
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/97 , A61K2800/80 , A61Q19/08
Abstract: PURPOSE: A cosmetic composition containing Sctellaria baicalensis georgi extract is provided to suppress expression of elastase and collagenase and prevent aging. CONSTITUTION: A cosmetic composition for anti-aging contains Sctellaria baicalensis georgi extract. A method for producing Sctellaria baicalensis georgi extract comprises: a step of boiling, steaming, roasting, and frying the Sctellaria baicalensis georgi in fire through processing herbal medicine; and a step of extracting Sctellaria baicalensis georgi extract using water or organic solvent to obtain extract. The organic solvent is ethanol, methanol, butanol, ether, ethyl acetate or chloroform.
Abstract translation: 目的：提供含有西葫芦提取物的化妆品，以抑制弹性蛋白酶和胶原酶的表达，并防止老化。 构成：抗衰老化妆品组合物含有西葫芦提取物。 一种生产西葫芦提取物的方法，包括：通过加工草药煮沸，蒸，焙烧，煎炸西葫芦; 并用水或有机溶剂提取西葫芦提取物提取物的步骤。 有机溶剂为乙醇，甲醇，丁醇，乙醚，乙酸乙酯或氯仿。
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公开(公告)号：KR1020090093245A
公开(公告)日：2009-09-02
申请号：KR1020080018672
申请日：2008-02-29
Applicant: (주)아모레퍼시픽 , 경상대학교산학협력단
CPC classification number: C07K14/47 , C12Q1/6876 , C12Q2600/136 , G01N33/5008 , G01N33/68
Abstract: A bio marker for diagnosing hyperpigmentation disposition of skin is provided to rapidly and sensitively predict the possibility of pigmentation. A bio marker for diagnosing skin of hyperpigmentation disposition comprises a gene of which expression is increased or decreased by UV irradiation. A kit for diagnosing hyperpigmentation disposition comprises a polynucleotide of the bio marker gene or its fragment and solid support in which one or more polynucleotide is conjugated on the surface. A method for screening an inhibitor of hyperpigmentation disposition comprises: a step of treating test material in the bio marker gene; and a step of confirming whether the test material suppresses or inhibits the expression of the gene.
Abstract translation: 提供用于诊断皮肤色素沉着过度的生物标记，以快速和敏感地预测色素沉着的可能性。 用于诊断色素沉着过度皮肤的生物标志物包括通过UV照射增加或减少表达的基因。 用于诊断色素沉着过度的试剂盒包括生物标记基因的多核苷酸或其片段和固体支持物，其中一个或多个多核苷酸在表面上缀合。 一种筛选色素沉着过度抑制剂的方法，包括：在生物标记基因中处理试验材料的步骤; 以及确认测试材料是否抑制或抑制基因表达的步骤。
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公开(公告)号：KR1020070070300A
公开(公告)日：2007-07-04
申请号：KR1020050069505
申请日：2005-07-29
Applicant: (주)아모레퍼시픽
CPC classification number: C12N15/113 , A61K8/606 , A61K31/7105 , A61Q19/02 , C12N2310/141
Abstract: A method for inhibiting melanosome migration by using prohibitin siRNA(small interference RNA) is provided to inhibit expression of prohibitin in a melanin synthesis cell and uniformed distribution of melanosome in the melanin synthesis cell, so that the skin is whitened. The melanosome migration to the end of melanin synthesis cell is inhibited by administering prohibitin siRNA into the melanin synthesis cell, melan-a, thereby inhibiting binding of prohibitin to melanophilin as a melanosome vehicle and uniformed distribution of melanosome in the melanin synthesis cell.
Abstract translation: 提供了通过使用prohibitin siRNA（小干扰RNA）抑制黑素体迁移的方法，以抑制黑色素合成细胞中的禁忌蛋白的表达和黑色素合成细胞中黑素体的均匀分布，从而使皮肤变白。 黑色素细胞迁移到黑色素合成细胞末端受到抑制黑色素合成细胞，黑色素a的抑制蛋白siRNA，从而抑制黑素素作为黑素体载体和黑素体合成细胞中黑素体分布均匀的结合。
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Patent Agency Ranking
公开(公告)号：KR1020040059139A
公开(公告)日：2004-07-05
申请号：KR1020020085716
申请日：2002-12-28
Applicant: (주)아모레퍼시픽
IPC: A61K31/704
CPC classification number: A61K31/70
Abstract: PURPOSE: Provided is a controlling agent of Bcl-2 expression which characteristically contains ginsenoside F1(20-O-beta-D-glucopyranosyl-20(S)-protopanaxatriol) represented by the formula(1), as an active ingredient. It prevents apoptosis caused by radiating low doses of ultraviolet rays, while promoting apoptosis when radiating high doses of ultraviolet rays, therefore it removes the risk of cancers. CONSTITUTION: A controlling agent of the expression of Bcl-2 is characterized by containing ginsenoside F1(20-O-beta-D-glucopyranosyl-20(S)-protopanaxatriol), which is represented by the formula(1), as an active ingredient. It inhibits the decrease of Bcl-2 expression caused by radiating ultraviolet rays. Therefore, it prevents apoptosis by the radiation of low doses of ultraviolet rays, but promotes apoptosis by the radiation of high doses of ultraviolet rays.
Abstract translation: 目的：提供一种Bcl-2表达的控制剂，其特征在于含有式（1）所示的人参皂甙F1（20-O-β-D-吡喃葡萄糖基-20（S） - 原人参三醇）作为活性成分。 防止辐射低剂量紫外线引起的细胞凋亡，同时在辐射高剂量的紫外线时促进细胞凋亡，从而消除癌症的风险。 构成：Bcl-2表达的控制剂的特征在于将由式（1）表示的人参皂甙F1（20-O-β-D-吡喃葡萄糖基-20（S） - 原人参三醇）作为活性物质 成分。 它抑制由辐射紫外线引起的Bcl-2表达的降低。 因此，通过低剂量的紫外线辐射可防止细胞凋亡，但通过高剂量紫外线的辐射促进细胞凋亡。
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