민감성 피부 진단용 바이오 마커 및 이를 이용한 진단 키트
    66.
    发明公开
    민감성 피부 진단용 바이오 마커 및 이를 이용한 진단 키트 有权
    用于预测敏感性皮肤和测试套件的生物标记

    公开(公告)号:KR1020090123049A

    公开(公告)日:2009-12-02

    申请号:KR1020080048930

    申请日:2008-05-27

    CPC classification number: C12Q1/6883 C12Q2600/136

    Abstract: PURPOSE: A biomarker of which expression is specifically decreased or suppressed in the sensitive skin is provided to quickly diagnose sensitive skin and used for screening a relieving agent. CONSTITUTION: A biomarker for diagnosing sensitive skin contains gene of which expression is decreased or increased in the sensitive skin compared to healthy skin or a protein encoding the gene. A method for screening a relieving agent of sensitivity comprises: a step of conjugating a candidate agent to a protein encoded by a gene of which expression is increased or decreased in the sensitive skin; and a step of confirming the suppression of protein activity.

    Abstract translation: 目的:提供敏感皮肤中特异性降低或抑制表达的生物标志物,以快速诊断敏感皮肤并用于筛选缓解剂。 构成:与健康皮肤或编码该基因的蛋白质相比,用于诊断敏感皮肤的生物标志物含有敏感皮肤中表达降低或增加的基因。 用于筛选敏感性缓释剂的方法包括:将候选试剂与由敏感皮肤中表达增加或减少的基因编码的蛋白质缀合的步骤; 以及确认蛋白质活性抑制的步骤。

    민감성 피부 진단용 바이오 마커 및 이를 이용한 진단 키트
    69.
    发明公开
    민감성 피부 진단용 바이오 마커 및 이를 이용한 진단 키트 有权
    用于预测敏感性皮肤和测试套件的生物标记

    公开(公告)号:KR1020140123034A

    公开(公告)日:2014-10-21

    申请号:KR1020140124120

    申请日:2014-09-18

    CPC classification number: C12Q1/6844

    Abstract: Disclosed is a biomarker of which gene expression levels are specifically increased or reduced for sensitive skin. The biomarker specific to sensitive skin is used in such a diagnostic kit for sensitive skin and a screening method of an abirritant. The biomarker for diagnosis of sensitive skin according to the present invention contains one or more gene selected from a group consisting of HLA-C, TCEA1, IGHA1, TFRC, S100A8, LOC652128, SERPINB13, EHF, FLJ10781, TP63, CDH1, TNFRSF19, GM2A, FKBP5, PI3, PSPH, HORMAD1, SPRR2G, and ACTR2 or a group consisting of KBTBD10, TTN, ACTA1, MYBPC1, MB, MYOZ1, TPM1, CA3, CASQ1, ENO3, RBP4, GYG2, PPP1R1A, PYGM, G0S2, NEB, H19, LIPE, PLIN, H19, GPAM, FABP4, CIDEC, LPL, PCK1, ADIPOQ, PDE3B, ACVR1C, LPL, FABP4, DKFZP761N09121, TNMD, ATP6V1B1, C8orf22, and CRISP3.

    Abstract translation: 公开了一种生物标志物,其敏感性皮肤基因表达水平被特异地增加或降低。 敏感皮肤特异性的生物标志物用于敏感皮肤的诊断试剂盒和刺激物的筛选方法。 根据本发明的敏感性皮肤诊断用生物标志物含有选自HLA-C,TCEA1,IGHA1,TFRC,S100A8,LOC652128,SERPINB13,EHF,FLJ10781,TP63,CDH1,TNFRSF19,GM2A ,FKBP5,PI3,PSPH,HORMAD1,SPRR2G和ACTR2或由KBTBD10,TTN,ACTA1,MYBPC1,MB,MYOZ1,TPM1,CA3,CASQ1,ENO3,RBP4,GYG2,PPP1R1A,PYGM,G0S2,NEB, H19,LIPE,PLIN,H19,GPAM,FABP4,CIDEC,LPL,PCK1,ADIPOQ,PDE3B,ACVR1C,LPL,FABP4,DKFZP761N09121,TNMD,ATP6V1B1,C8orf22和CRISP3。

    뉴로코스메틱 피부 미용방법, 피부 미용 물질 스크리닝방법 및 피부 미용 물질
    70.
    发明公开
    뉴로코스메틱 피부 미용방법, 피부 미용 물질 스크리닝방법 및 피부 미용 물질 有权
    神经性皮肤护理方法,用于筛选皮肤化妆品的方法和皮肤化妆品

    公开(公告)号:KR1020100000391A

    公开(公告)日:2010-01-06

    申请号:KR1020080059872

    申请日:2008-06-24

    CPC classification number: A61K8/97 A61Q19/08

    Abstract: PURPOSE: A method for screening a cosmetic material and cosmetic composition containing a material suppressing TRPV-1(transient receptor potential family V-1) are provided to select a target material which is effective in anti-aging and reduce skin irritation. CONSTITUTION: A material which suppresses activation of TRPV-1(transient receptor potential family V-1) contains extract isolated from one or more selected from Prunus mume Sieb. et Zucc., Pleuropterus multflorus, and Atractylodes japonica Koidxumi or Atractylodes ovate Koidzumi. A cosmetic composition contains 0.001-10 weight%, preferably 0.01-5 weight% of the extract. The cosmetic composition is used in the form of nutrition skin, massage cream, pack gel or lotion, ointment, cream, patch or spray.

    Abstract translation: 目的:提供一种筛选含有抑制TRPV-1(瞬时受体潜能家族V-1)的物质的美容材料和化妆品组合物的方法,以选择有效抗衰老和降低皮肤刺激性的目标材料。 构成:抑制TRPV-1(瞬时受体电位家族V-1)活化的物质含有从一种或多种选自杏仁酵母中分离的提取物。 等等,Pleuropterus multflorus和Atractylodes japonica Koidxumi或Atractylodes ovate Koidzumi。 化妆品组合物含有0.001-10重量%,优选0.01-5重量%的提取物。 化妆品组合物以营养皮肤,按摩膏,包装凝胶或洗剂,软膏,霜剂,贴剂或喷雾剂的形式使用。

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