公开(公告)号：NO853695A

公开(公告)日：1986-03-24

申请号：NO853695

申请日：1985-09-20

Applicant: BASF AG

Inventor： FRICKEL FRITZ-FRIEDER ,  NUERRENBACH AXEL ,  THEOBALD HANS

IPC: A61K31/41 ,  A61P17/00 ,  A61P17/16 ,  A61P19/06 ,  A61P29/00 ,  A61P35/00 ,  C07D261/08 ,  C07D261/10 ,  C07D261/18 ,  C07D413/04 ,  C07D521/00 ,  C07D261/00

CPC classification number: C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D261/08 ,  C07D261/18 ,  C07D413/04

公开(公告)号：NO853694L

公开(公告)日：1986-03-24

申请号：NO853694

申请日：1985-09-20

Applicant: BASF AG

Inventor： FRICKEL FRITZ-FRIEDER ,  NUERRENBACH AXEL ,  THYES MARCO

IPC: A61K31/41 ,  A61P17/00 ,  A61P29/00 ,  A61P35/00 ,  C07D20060101 ,  C07D257/04 ,  C07D257/00

公开(公告)号：NO853694A

公开(公告)日：1986-03-24

申请号：NO853694

申请日：1985-09-20

Applicant: BASF AG

Inventor： FRICKEL FRITZ-FRIEDER ,  NUERRENBACH AXEL ,  THYES MARCO

IPC: A61K31/41 ,  A61P17/00 ,  A61P29/00 ,  A61P35/00 ,  C07D20060101 ,  C07D257/04 ,  C07D257/00

CPC classification number: C07D257/04

公开(公告)号：FI853623L

公开(公告)日：1986-03-23

申请号：FI853623

申请日：1985-09-20

Applicant: BASF AG

Inventor： WUEST HANS-HEINER ,  FRICKEL FRITZ-FRIEDER ,  NUERRENBACH AXEL

IPC: C07F9/09 ,  A61K20060101 ,  A61K31/66 ,  A61P17/00 ,  A61P29/00 ,  A61P35/00 ,  C07F20060101 ,  C07F9/11 ,  C07F9/12 ,  C07F9/24 ,  C07F9/59 ,  C07F9/6533 ,  C07F9/6574 ,  C07F9/6584 ,  C07F

Abstract: A vinylbenzyl phosphate of the formula I where A, R1, R2, R3, R4, R5, R6, R7, R8 and R9 have the meanings stated in the description, and their preparation are described. The substances are useful for the treatment of disorders.

公开(公告)号：FI853621A0

公开(公告)日：1985-09-20

申请号：FI853621

申请日：1985-09-20

Applicant: BASF AG

Inventor： FRICKEL FRITZ-FRIEDER ,  NUERRENBACH AXEL ,  THYES MARCO

IPC: A61K31/41 ,  A61P17/00 ,  A61P29/00 ,  A61P35/00 ,  C07D20060101 ,  C07D257/04 ,  C07D

公开(公告)号：HU184936B

公开(公告)日：1984-11-28

申请号：HU248480

申请日：1980-10-13

Applicant: BASF AG

Inventor： FRICKEL FRITZ-FRIEDER ,  FRANKE ALBRECHT ,  PHILIPSBORN GERDA ,  MUELLER CLAUS D ,  LENKE DIETER

IPC: A61K31/40 ,  A61K31/403 ,  A61K31/404 ,  A61K31/4427 ,  A61K31/445 ,  A61K31/454 ,  A61K31/47 ,  A61P9/00 ,  A61P9/06 ,  C07C271/22 ,  C07D207/34 ,  C07D207/36 ,  C07D209/42 ,  C07D401/12 ,  C07D401/14

Abstract: Substituted piperidinoalkyl ethers of 4,5-dialkyl-3-hydroxy-pyrrole-2-carboxylic acid esters and their physiologically tolerated addition salts with acids, processes for their preparation and pharmaceutical formulations which contain these compounds and are useful in the treatment of cardiac arrhythmias.

公开(公告)号：DK146741B

公开(公告)日：1983-12-19

申请号：DK174979

申请日：1979-04-27

Applicant: BASF AG

Inventor： THIEME PETER C ,  FRICKEL FRITZ-FRIEDER ,  HAGEN HELMUT ,  FRANKE ALBRECHT ,  LENKE DIETER ,  GRIES JOSEF

IPC: A61K31/41 ,  A61K31/433 ,  A61P9/00 ,  A61P9/06 ,  A61P9/12 ,  C07D285/12 ,  C07D417/12

Abstract: Alkylaminopropanol derivatives of 2-methyl-5-(2-hydroxystyryl)-1,3,4-thiadiazole and their addition salts with acids, their preparation, and pharmaceutical formulations, containing these compounds, which may be used for the treatment of coronary diseases of the heart, of hypertonia and of cardiac arrhythmias.

公开(公告)号：LU84703A1

公开(公告)日：1983-11-17

申请号：LU84703

申请日：1983-03-22

Applicant: BASF AG

Inventor： FRICKEL FRITZ-FRIEDER ,  NUERRENBACH AXEL

IPC: C07C63/66 ,  C07D257/06 ,  C07G ,  A61K ,  C07D

公开(公告)号：FI830163L

公开(公告)日：1983-07-24

申请号：FI830163

申请日：1983-01-18

Applicant: BASF AG

Inventor： FRICKEL FRITZ-FRIEDER ,  NUERRENBACH AXEL

IPC: A61K31/165 ,  A61K31/19 ,  A61K31/235 ,  A61K31/41 ,  C07C63/66 ,  C07C69/76 ,  C07D257/06 ,  C07C

公开(公告)号：HU178989B

公开(公告)日：1982-07-28

申请号：HUBA003778

申请日：1979-04-27

Applicant: BASF AG

Inventor： THIEME PETER C ,  FRICKEL FRITZ-FRIEDER ,  THEOBALD HANS ,  FRANKE ALBRECHT ,  LENKE DIETER ,  GRIES JOSEF

IPC: A61K31/41 ,  A61K31/42 ,  A61P9/00 ,  A61P9/06 ,  A61P9/12 ,  A61P25/02 ,  C07D261/08

Abstract: Alkylamino-propanol derivatives of 3-alkyl-5-(2-hydroxystyryl)-isoxazole, of the general formula where R is hydrogen, alkyl of 1 to 8 carbon atoms, which is unsubstituted or substituted by hydroxyl, alkoxy of 1 to 3 carbon atoms or cycloalkyl with 3 to 8 carbon atoms in the ring, alkenyl or alkynyl of 2 to 8 carbon atoms, or cycloalkyl with 3 to 8 carbon atoms in the ring, the cycloalkyl rings being unsubstituted or mono- or di-substituted by alkyl of 1 to 3 carbon atoms, and R' is alkyl of 1 to 4 carbon atoms, and their addition salts with physiologically acceptable acids, their preparation, and pharmaceutical formulations which contain these compounds and which can be used as valuable drugs in the treatment of hypertonia, coronary diseases of the heart and cardiac arrhythmias.