Abstract:
발명은 쌀 추출물의 수면 장애, 불안 또는 우울증의 개선, 예방 또는 치료를 위한 신규 용도를 제공한다. 쌀 추출물은 종래 수면유도제로 사용되는 의약인 디아제팜과 거의 동일한 수준 또는 향상된 입면시간의 감소, 수면 지속시간의 증가 및 논램 수면의 증가 효과가 있다. 쌀 추출물은 천연물로서 장기간 사용하여도 인지장애(cognitive impairment), 내성 또는 의존성이 형성되는 부작용이 없다.
Abstract:
PURPOSE: A composition for preventing or treating depression is provided to suppress nuclear translocation of a glucocorticoid receptor, thereby suppressing signal transduction induced by stress and showing anti-stress effect. CONSTITUTION: A composition for preventing or treating depression contains an ethanol extract of Mori Cortex Radicis as an active ingredient. The extract is prepared by an ultrasonicator. The composition is prepared by adding sodium carbonate to the extract and dissolving an insoluble material. The composition suppresses the activity of a glucocorticoid receptor. The composition suppresses nuclear translocation of the glucocorticoid receptor.
Abstract:
PURPOSE: A method for manufacturing a composition containing xanthorrhizol with enhanced water miscibility comprising a step of mixing xanthorrhizol with an emulsifier mixture of glycerol and polyglycerin fatty acid ester is provided to remarkably enhance water miscibility of xanthorrhizol without an organic solvent, and to ensure safety of the composition. CONSTITUTION: A method for preparing a composition containing xanthorrhizol with enhanced water miscibility comprises: a step of mixing 0.01-5% of xanthorrhizol and an emulsifier mixture containing 1-10wt% of glycerol and 1-10wt% of polyglycerin fatty acid ester; and a step of homogenizing the mixture by an ultrasonicator. The homogenization enhances stability. The concentration of xanthorrhizol is 40-70%.
Abstract:
PURPOSE: An extract of rice, rice bran, or rice husks is provided to be used as a natural anti-histamine agent, to prevent or treat allergic rhinitis, inflammatory bowel diseases, asthma, bronchitis, vomiting, gastric and duodenal ulcer, gastroesophageal reflux, sleep disorder, anxiety, and depression without side effects. CONSTITUTION: A pharmaceutical composition for suppressing activity of a histamine receptor contains an extract of rice, rice bran, or rice husks as an active ingredient. The pharmaceutical composition is used for preventing or treating allergic rhinitis, inflammatory bowel disease, asthma, bronchitis, vomiting, gastric and duodenal ulcer, gastroesophageal reflux, sleep disorder, anxiety, and depression. The extract is prepared by using water, an organic solvent, or a mixture thereof. The organic solvent is selected among low carbon number alcohol, hexane, acetone, ethyl acetate, chloroform, and diethyl ether. [Reference numerals] (AA) Hypnagogue time(minutes); (BB) BEE-H sub-fraction(250mg/kg)
Abstract:
본 발명은 유효성분으로 아스코르브산(ascorbic acid), 베타-D-글루칸(β-D-glucan), 헤스페레틴(hesperetin), 멜라토닌(melatonin), 진세노사이드-Rb1(ginsenoside-Rb1) 및 진세노사이드-Rg1(ginsenoside-Rg1)으로 이루어진 군으로부터 선택되는 하나 이상의 성분을 함유하는 식욕억제 조성물에 관한 것으로, 더욱 상세하게는 식욕촉진 호르몬인 그렐린(ghrelin)의 활성을 억제함으로써 식욕억제 효과를 갖는 식욕억제 조성물 및 아스코르브산(ascorbic acid), 베타-D-글루칸(β-D-glucan), 헤스페레틴(hesperetin), 멜라토닌(melatonin), 진세노사이드-Rb1(ginsenoside-Rb1) 및 진세노사이드-Rg1(ginsenoside-Rg1)으로 이루어진 군으로부터 선택되는 하나 이상의 성분을 유효성분으로 함유하는 식욕억제용 기능성 식품에 관한 것이다.
Abstract:
본 발명은 친환경 통과일 사과 식초의 제조 방법에 관한 것으로, 더욱 상세하게는 껍질을 제거하지 않은 친환경사과를 세척하고 칼로 2-4 등분한 후, 잘게 조각을 내는 단계; 조각낸 사과를 콜로이드 밀을 이용하여 분쇄하는 단계; 상기 분쇄된 사과 분쇄액에 유산균을 첨가하여 잡균을 제거한 후, 효모균을 첨가하여 알코올 발효하는 단계; 상기 알코올 발효된 사과 발효액에 초산균 및 자연발효 사과 식초로 이루어진 군으로부터 선택되는 하나 이상을 혼합하여 발효하는 단계; 상기 발효된 사과 식초를 디켄트(decanter) 처리한 후 천연 갈변 방지제인 루바브 주스 3~7 중량%를 혼합하는 단계; 및 상기 사과 식초를 고전압 펄스(pulse)를 이용하여 살균하고 용기에 충진하거나 또는 사과 식초를 용기에 충진하고 초고압 살균하는 단계를 포함하는 갈변이 방지되고, 첨가물이 첨가되지 않은 친환경 통과일 사과 식초의 제조 방법 및 상기 방법에 의해 제조된 사과 식초에 관한 것이다.
Abstract:
PURPOSE: A rice bran extract for preventing or treating sleep disorder, anxiety, or depression is provided to reduce sleep latency and to increase non-REM sleep without side effects. CONSTITUTION: A pharmaceutical composition for preventing or treating sleep disorder, anxiety, or depression contains rice bran extract as an active ingredient. The extract is prepared using water, organic solvent, or a mixture thereof. The organic solvent is low carbon number alcohol, hexane, acetone, ethyl acetate, chloroform, or diethyl ether. The extract is also a fraction prepared by fractioning the organic solvent extract with a second organic solvent. A food composition for preventing or treating sleep disorder, anxiety, or depression contains the extract as an active ingredient.
Abstract:
PURPOSE: A food ingredient composition for suppressing the appetite of a user is provided to prevent the generation of side effect when using the composition for a long time. CONSTITUTION: A food ingredient composition for suppressing the appetite of a user contains more than one component selected from the group consisting of 3-hydroxy flavone, rutin, quercetin, flavonone, naringin, and hesperidin. The suppressing effect of the appetite is obtained by controlling the activity of ghrelin promoting the appetite of the user. The composition suppresses the activity of the ghrelin at 60-100deg C.
Abstract:
PURPOSE: A method for producing eco-friendly apple vinegar is provided to prevent browning without additives and damage of functional ingredients and nutrient. CONSTITUTION: A method for producing eco-friendly apple vinegar without additives comprises: a step of washing apples and cutting the apples into 2-4 sections; a step of pulverizing the apples using a colloid mill; a step of removing bacteria and adding yeast for alcohol fermentation; a step of mixing the acetobacter or naturally fermented apple vinegar to the apple fermented liquid; a step of decanting the fermented apple vinegar and mixing with 3-7 wt% of rhubarb juice; and a step of sterilizing the apple vinegar by high voltage pulse.