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公开(公告)号：SK899A3
公开(公告)日：1999-06-11
申请号：SK899
申请日：1997-07-29
Applicant: BASF AG
Inventor： BAUCKE DORIT , LANGE UDO , MACK HELMUT , SEITZ WERNER , ZIERKE THOMAS , HOFFKEN HANS W , HORNBERGER WILFRIED
IPC: A61K38/00 , A61K38/05 , A61P7/02 , A61P29/00 , A61P35/00 , A61P35/04 , C07K5/06 , C07K5/062 , C07K5/065
Abstract: PCT No. PCT/EP97/04104 Sec. 371 Date Feb. 10, 1999 Sec. 102(e) Date Feb. 10, 1999 PCT Filed Jul. 29, 1997 PCT Pub. No. WO98/06741 PCT Pub. Date Feb. 19, 1998Compounds of the formula where A, B, E and D have the meanings indicated in the description, and their preparation are described. The substances are suitable for controlling diseases.
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公开(公告)号：HU9802570A2
公开(公告)日：1999-04-28
申请号：HU9802570
申请日：1996-07-12
Applicant: BASF AG
Inventor： AMBERG WILHELM , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , JANSSEN BERND , KLING ANDREAS , MUELLER STEFAN , RITTER KURT , ULRICH KARL , ZIERKE THOMAS
IPC: C07K1/02 , C07K1/12 , C07K5/06 , C07K5/078 , C07K5/08 , C07K5/083 , C07K5/10 , C07K5/103 , C07K7/06
Abstract: PCT No. PCT/EP96/03073 Sec. 371 Date Jan. 13, 1998 Sec. 102(e) Date Jan. 13, 1998 PCT Filed Jul. 12, 1996 PCT Pub. No. WO97/05162 PCT Pub. Date Feb. 13, 1997A process for preparing pentapeptides of the formula I where A and R1-R3 have the stated meanings, comprises assembling the pentapeptide stepwise starting from a prolinamide of the formula II where R1 and R2 have the abovementioned meanings, and eliminating the group -NR1R2 by hydrolysis where appropriate the peptide obtained in this way.
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公开(公告)号：NO990667L
公开(公告)日：1999-04-12
申请号：NO990667
申请日：1999-02-12
Applicant: BASF AG
Inventor： BAUCKE DORIT , LANGE UDO , MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , ZIERKE THOMAS , HOEFFKEN HANS WOLFGANG , HORNBERGER WILFRIED
IPC: A61K31/40 , A61K31/44 , A61K38/00 , A61K38/05 , A61P1/18 , A61P7/02 , A61P11/02 , A61P11/06 , A61P17/00 , A61P19/02 , A61P29/00 , A61P43/00 , C07D207/22 , C07D211/78 , C07K5/00 , C07K5/02 , C07K5/083
Abstract: Compounds of the formula Iwhere R, R1, R2, R3, R4, R5 and R6, and l, m and n have the meanings stated in the description, and their preparation are described. The novel compounds are suitable for controlling diseases.
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公开(公告)号：NO991010L
公开(公告)日：1999-03-02
申请号：NO991010
申请日：1999-03-02
Applicant: BASF AG
Inventor： SCHOFER BERND , ZIERKE THOMAS
IPC: C07D213/81 , C07B43/00 , C07C257/10 , C07D213/73 , C07D213/78 , C07D271/06 , C07D401/12 , C07D413/12 , C07K1/06 , C07K5/062
Abstract: A process for preparing amidines and their salts with inorganic or organic acids comprises reacting the corresponding nitrile with ammonia, C1-C6-alkylamine or hydrazine in the presence of a mercaptocarboxylic acid and in the presence or absence of an in-organic or organic ammonium salt.
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公开(公告)号：NO991010A
公开(公告)日：1999-03-02
申请号：NO991010
申请日：1999-03-02
Applicant: BASF AG
Inventor： SCHOFER BERND , ZIERKE THOMAS
IPC: C07D213/81 , C07B43/00 , C07C257/10 , C07D213/73 , C07D213/78 , C07D401/12 , C07K1/06 , C07K5/062
CPC classification number: C07D213/78 , C07C257/10 , C07D401/12
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Patent Agency Ranking
公开(公告)号：NO990662A
公开(公告)日：1999-02-12
申请号：NO990662
申请日：1999-02-12
Applicant: BASF AG
Inventor： BAUCKE DORIT , LANGE UDO , MACK HELMUT , SEITZ WERNER , ZIERKE THOMAS , HOEFFKEN HANS WOLFGANG , HORNBERGER WILFRIED
IPC: A61K38/00 , A61K38/05 , A61P7/02 , A61P29/00 , A61P35/00 , A61P35/04 , C07K5/06 , C07K5/062 , C07K5/065
CPC classification number: C07K5/06078 , A61K38/00
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公开(公告)号：AU8475898A
公开(公告)日：1999-02-10
申请号：AU8475898
申请日：1998-07-07
Applicant: BASF AG , BASF BIORESEARCH CORP
Inventor： JANSSEN BERND , BARLOZZARI TERESA , HAUPT ANDREAS , ZIERKE THOMAS , KLING ANDREAS
Abstract: Compounds of the present invention include cell growth inhibitors which are peptides of Formula I, A-B-D-E-F-(G)r-(K)s-L (I), and acid salts thereof, wherein A, B, D, E, F, G and K are α-amino acid residues, and s and r are each, independently, 0 or 1. L is a monovalent radical, such as, for example, an amino group, an N-substituted amino group, a &bgr;-hydroxylamino group, a hydrazido group, an alkoxy group, a thioalkoxy group, an aminoxy group, or an oximato group. The present invention also includes a method for treating cancer in a mammal, such as a human, comprising administering to the mammal an effective amount of a compound of Formula I in a pharmaceutically acceptable composition.
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公开(公告)号：AU699579B2
公开(公告)日：1998-12-10
申请号：AU4255996
申请日：1995-11-25
Applicant: BASF AG
Inventor： BOHM HANS JOACHIM , KOSER STEFAN , MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , HOFFKEN HANS WOLFGANG , HORNBERGER WILFRIED , ZIERKE THOMAS
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公开(公告)号：SK104697A3
公开(公告)日：1998-11-04
申请号：SK104697
申请日：1996-02-12
Applicant: BASF AG
Inventor： BOHM HANS-JOACHIM , HOFFKEN HANS W , HORNBERGER WILFRIED , KOSER STEFAN , MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , ZIERKE THOMAS
IPC: A61K31/00 , A61K38/55 , A61P7/02 , C07D205/04 , C07D207/16 , C07D213/53 , C07D213/63 , C07D213/72 , C07D213/78 , C07D213/79 , C07D239/28 , C07D241/14 , C07D241/24 , C07D401/12 , C07K5/06 , C07K5/062 , C07K5/078 , A61K31/40 , A61K31/445 , A61K31/495
Abstract: The invention relates to a compound of the formula I: or a salt thereof with a physiologically tolerated acid, or stereoisomers thereof, wherein R 1 , R 2 , A, B, C and D have the meanings described in the specification.
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公开(公告)号：NO982711D0
公开(公告)日：1998-06-12
申请号：NO982711
申请日：1998-06-12
Applicant: BASF AG
Inventor： AMBERG WILHELM , BARLOZZARI TERESA , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , HEGE HANS-GUENTHER , JANSSEN BERND , KLING ANDREAS , LIETZ HELMUT , RITTER KURT , ULLRICH MARTINA , WEYMANN JUERGEN , ZIERKE THOMAS
Abstract: Novel peptides of the formula R R N-CHX-CO-A-B-D-E-(G)s-K in which R , R , A, B, D, E, G, K, X, and s have the meanings stated in the description, and the preparation thereof are described. The novel peptides have an antineoplastic effect.
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