公开(公告)号：BR8906608A

公开(公告)日：1990-09-04

申请号：BR8906608

申请日：1989-12-20

Applicant: HOECHST AG

Inventor： STARK HERBERT ,  SALBECK GERHARD ,  BONIN WERNER

IPC: A61K31/415 ,  A61P33/00 ,  C07D233/20 ,  C07D233/22 ,  C07D233/24 ,  A01N43/50

Abstract: The present invention relates to agents for systemic combating of ectoperasites in host animals, containing a compound of the formul I (I) in which R1 denotes hydrogen, (C1-C5)-alkyl, (C1-C3)-halogenoalkyl or halogen; R2 and R3 independently of one another denote (c1-C5)-alkyl, (C2-C5)-alkenyl, (C2-C5)-alkynyl, (C3-C7)-cycloalkyl, (C3-C7)-cycloalkenyl, (C1-C3)-halogenoalkyl, halogen, cyano, nitro, (C1-C5)-alkoxy, (C1 -C3)-alkoxy-C1-C3)-alkyl, (C1-C3)-halogenoalkoxy or (C1-C3)-alkylthio, or R2 and R3 together form a polymethylene chain having 2 to 5 carbon atoms: R4 denotes hydrogen, (c1-C10)-alkyl, (C2-C5)-alkenyl or (C3-C7)-cycloalkyl; R5 denotes hydrogen, (C1-C10)-alkyl, (C3-C5)-alkenyl, C3-C5)-alkynyl, (C3-C7)- cycloalkyl, (C3-C7)-cycloalkenyl, (C1-C3)-halogenoalkyl or (C1-C3)-alkoxy-(C hd 1-C3)-alkyl; X denotes oxygen, sulfur or an -NR6-group; and R6 denotes hydrogen, (C1-C5)-alkyl, (C3-C5)-alkenyl, C3-C5)-alkynyl, (C3-C7)-cycloalkyl, C3-C7)-cycloalkenyl, (C1-C3)-halogenoalkyl or (C1-C3)-alkoxy-(C1 -C3)-alkyl, or biologically tolerated acid addition salts thereof. The compounds of the formulas I are novel in some cases and are likewise included in the invention.

公开(公告)号：PT89151A

公开(公告)日：1989-12-29

申请号：PT8915188

申请日：1988-12-02

Applicant: HOECHST AG

Inventor： BONIN WERNER ,  KNAUF WERNER ,  KERN MANFRED ,  WALTERSDORFER ANNA ,  KOCH VOLKER ,  SCHNATTERER STEFAN

IPC: A01N43/88 ,  A01N47/30 ,  A01N47/34 ,  A01P7/02 ,  A01P7/04 ,  C07C317/24 ,  C07C317/42 ,  C07C323/22 ,  C07C323/27 ,  C07C323/44 ,  C07C335/26 ,  C07D273/04 ,  C07C147/12 ,  C07C147/14 ,  C07C149/437

公开(公告)号：BR8702772A

公开(公告)日：1988-03-01

申请号：BR8702772

申请日：1987-05-29

Applicant: HOECHST AG

Inventor： GIENCKE WOLFGANG ,  MILDENBERGER HILMAR ,  HEUBACH GUENTHER ,  SACHSE BURKHARD ,  FUSS ANDREAS ,  WALTERSDORFER ANNA ,  KNAUF WERNER ,  KERN MANFRED ,  BONIN WERNER

IPC: A01N43/54 ,  C07D239/42 ,  C07D239/46 ,  C07D239/47 ,  C07D239/48

公开(公告)号：AU6675786A

公开(公告)日：1987-06-25

申请号：AU6675786

申请日：1986-12-19

Applicant: HOECHST AG

Inventor： KOCH VOLKER ,  FUSS ANDREAS ,  BONIN WERNER ,  KNAUF WERNER ,  WALTERSDORFER ANNA

IPC: A01N43/824 ,  A01N43/88 ,  A01N47/34 ,  A01N47/36 ,  C07D213/64 ,  C07D213/69 ,  C07D213/75 ,  C07D213/89 ,  C07D413/12 ,  A01N43/50 ,  A01N43/54 ,  A01N43/78 ,  A01N43/76

Abstract: The compounds of the formula (I) (I) in which A denotes N or N->0, R denotes a radical of the formula R4-CY1-NR5-CY2-NR6-, +TR R1 denotes halogen, alkyl, alkenyl, alkynyl, alkoxy, alkoxycarbonyl or alkylcarbonyl, where these radicals may be halogenated, nitro, cyano or carboxyl, R2 denotes halogenated alkoxy, halogenated alkenyloxy or halogenated alkynloxy, R3 denotes halogen, n denotes 0, 1 or 2, m denotes 0, 1, 2 or 3, and p denotes 0 or 1, and also the salts thereof, are advantageously suitable for combating noxious insects, acarides, nematodes or mollusks.

公开(公告)号：ZA817429B

公开(公告)日：1982-09-29

申请号：ZA817429

申请日：1981-10-27

Applicant: HOECHST AG

Inventor： WELTER WOLFGANG ,  MILDENBERGER HILMAR ,  KNAUF WERNER ,  WALTERSDORFER ANNA ,  BONIN WERNER

IPC: C07C69/007 ,  A01N37/10 ,  A01N37/34 ,  A01N53/00 ,  A01N53/08 ,  C07C67/00 ,  C07C69/753 ,  C07C253/00 ,  C07C255/38 ,  C07C

Abstract: Compounds of the formula wherein R1 denotes H, halogen, alkyl or CF3, R2 denotes H, halogen, alkyl or CF3, R3 denotes H, halogen, CN or alkyl, R4 denotes H, halogen, alkyl, phenyl or halogenophenyl, R5 denotes H, alkyl, alkynyl or CN and R6 denotes substituted dimethylcyclopropyl or 2-phenylisobutyl radicals, are effective insecticides and acaricides of the pyrethroid type.

公开(公告)号：ZA8107429B

公开(公告)日：1982-09-29

申请号：ZA8107429

申请日：1981-10-27

Applicant: HOECHST AG

Inventor： WELTER WOLFGANG ,  MILDENBERGER HILMAR ,  KNAUF WERNER ,  WALTERSDORFER ANNA ,  BONIN WERNER

IPC: C07C69/007 ,  A01N37/10 ,  A01N37/34 ,  A01N53/00 ,  A01N53/08 ,  C07C67/00 ,  C07C69/753 ,  C07C253/00 ,  C07C255/38 ,  C07C

CPC classification number: A01N53/00

公开(公告)号：ZW25881A1

公开(公告)日：1982-05-19

申请号：ZW25881

申请日：1981-10-26

Applicant: HOECHST AG

Inventor： WELTER WOLFGANG ,  MILDENBERGER HILMAR ,  KNAUF WERNER ,  WALTERSDORFER ANNA ,  BONIN WERNER

IPC: C07C69/007 ,  A01N37/10 ,  A01N37/34 ,  A01N53/00 ,  A01N53/08 ,  C07C67/00 ,  C07C69/753 ,  C07C253/00 ,  C07C255/38 ,  C07C ,  A01N

Abstract: Compounds of the formula wherein R1 denotes H, halogen, alkyl or CF3, R2 denotes H, halogen, alkyl or CF3, R3 denotes H, halogen, CN or alkyl, R4 denotes H, halogen, alkyl, phenyl or halogenophenyl, R5 denotes H, alkyl, alkynyl or CN and R6 denotes substituted dimethylcyclopropyl or 2-phenylisobutyl radicals, are effective insecticides and acaricides of the pyrethroid type.

公开(公告)号：CS181780B2

公开(公告)日：1978-03-31

申请号：CS182375

申请日：1975-03-18

Applicant: HOECHST AG

Inventor： STAEHLER GERHARD ,  EMMEL LUDWIG ,  BONIN WERNER

IPC: A01N57/16 ,  A01N57/24 ,  A01N57/34 ,  C07F9/653 ,  A01N9/36

Abstract: Mono- and dithiophosphonic acid esters of the formula I in which R is optionally substituted alkyl, cycloalkyl, cycloalkenyl, or optionally substituted phenyl, R' is optionally substituted alkyl, alkenyl, or cycloalkyl, R'' and R''' which are identical or different, are hydrogen, halogen, methyl, methoxy, nitro or trifluoromethyl, and X is oxygen or sulfur, are useful insecticides and acaricides.

公开(公告)号：CA2131545C

公开(公告)日：1999-03-16

申请号：CA2131545

申请日：1993-03-10

Applicant: HOECHST AG

Inventor： SCHAPER WOLFGANG ,  FREUSS RAINER ,  SALBECK GERHARD ,  BRAUN PETER ,  LUEMMEN PETER ,  BONIN WERNER ,  KNAUF WERNER ,  SACHSE BURKHARD ,  WALTERSDORFER ANNA ,  KERN MANFRED

IPC: A01N43/54 ,  A01N43/90 ,  A01P3/00 ,  A01P7/02 ,  A01P7/04 ,  C07D239/34 ,  C07D239/42 ,  C07D239/46 ,  C07D239/52 ,  C07D239/60 ,  C07D239/88 ,  C07D239/94 ,  C07D401/12 ,  C07D405/12 ,  C07D491/048 ,  C07D495/04 ,  C07D239/28 ,  C07D401/00 ,  A01N55/00 ,  C07F7/10 ,  C07D409/12 ,  A61K31/505 ,  A61K31/695 ,  C07D239/72

Abstract: The invention relates to substituted 4-amino- and 4-alkoxy-cycloalkylpyrimidines of the formula I, processes for their preparation, and their use as pesticides and fungicides. The compounds have the formula in which R1, R2, R3 and Q are as defined in the description, X is NH or oxygen and E is a bond or a 1- to 4-membered carbon chain.

公开(公告)号：ES2056149T3

公开(公告)日：1994-10-01

申请号：ES89109770

申请日：1989-05-30

Applicant: HOECHST AG

Inventor： BONIN WERNER ,  HABERMANN PAUL ,  TRIPIER DOMINIQUE ,  WOEHNER ELISABET

IPC: A61K38/55 ,  A61K35/56 ,  A61K38/00 ,  A61P7/02 ,  C07K1/14 ,  C07K1/16 ,  C07K14/00 ,  C07K14/435 ,  C07K14/44 ,  C07K14/81 ,  C07K15/08 ,  A61K37/02

Abstract: The invention relates to a new active substance-amblyommin-for anticoagulant therapy and to a process for the isolation thereof from hard ticks. The isolated protein having a thrombin-inhibitory action has a molecular weight of 20000 to 30000 dalton, an isoelectric point between 5.05 and 5.65 and the partial amino acid sequences Ile-Leu-Phe-Thr-Gln-Gly-Asn-X-Gly-Glu-Leu-Glu-Asn-X-Phe-Glu-, Lys-Ile-Leu-Phe-X-Gln-Gly- and Ala-Ser-Tyr-Ile-Val-X-Ser-Glu-Ser-Ile-Gln-Ile-Leu-X-Leu-Ser-Glu-Gly-Ile- in which each radical X can be identical or different and each represents a naturally occurring amino acid.