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71.
公开(公告)号:CA2068328A1
公开(公告)日:1991-05-10
申请号:CA2068328
申请日:1990-11-07
Applicant: HOECHST AG
Inventor: GIENCKE WOLFGANG , SACHSE BURKHARD , WICKE HEINRICH
IPC: A01N43/54 , C07D401/04
Abstract: - 43 - HOE 89/F 360 of the disclosure Pyrimidine derivatives, process for their preparation, agents containing them and their use as fungicides Compounds of the formula I (I) in which R1 is hydrogen, alkyl, alkoxyalkyl, alkylthioalkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, it being possible for the two last-mentioned radicals to be substituted in the cycloalkyl moiety, phenyl, phenoxyalkyl, phenylmercaptoalkyl, phenylalkyl or phenoxy-phenoxyalkyl, it being possible for this radical to be substituted in the phenyl moiety, R2, R3 and R4 are independently of one another hydrogen, alkyl or (subst.) phenyl, R5 is hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, it being possible for these two radicals to be substituted in the cycloalkyl moiety, haloalkyl, alkoxy, alkylthio, alkoxyalkyl, alkylthioalkyl, halogen, alkenyl, alkynyl, phenyl, phenoxy, phenylalkyl, phenoxyalkyl, phenylmercaptoalkyl, phenylmercapto, phenylalkoxy or phenylalkylthio, it being possible for these radicals to be substituted in the phenyl moiety, or alkenyloxy, alkynyloxy, haloalkoxy, alkoxyalkoxy or alkylthioalkylthio, R6 is hydrogen, alkyl, alkoxy, alkenyloxy, alkynyloxy, alkylthio, halogen, phenyl, it being possible for the phenyl radical to be substituted, R7, R8, R9 and R10 are independently of one another hyd rogen, halogen, nitro, cyano, alkyl, alkoxy, alkylthio, haloalkyl or haloalkoxy, R11 and R12 are independently of one another hydrogen or alkyl and n = 1-3, and their acid addition salts have advantageous fungicidal properties.
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公开(公告)号:PT94645A
公开(公告)日:1991-03-20
申请号:PT9464590
申请日:1990-07-10
Applicant: HOECHST AG
Inventor: GIENCKE WOLFGANG , SACHSE BURKHARD , WICKE HEINRICH
IPC: A01N43/54 , C07D401/04 , C07D401/14 , A01N43/40
Abstract: Compounds of the formula I … … in which …… R is H, alkyl, alkoxyalkyl, alkylthioalkyl, cycloalkyl, alkenyl, alkynyl, cycloalkylalkyl, substituted amino-alkyl phenyl, phenylalkyl, phenoxyalkyl, phenylmercaptoalkyl, phenoxyphenoxyalkyl, it being possible for these radicals to be substituted in the phenyl moiety, … R , R and R independently of one another are H, alkyl or phenyl which can be substituted, … R is H, alkyl, cycloalkyl, cycloalkylalkyl, haloalkyl, alkoxy, alkylthio, alkoxyalkyl, a radical R R N-, alkylthioalkyl, R R N-alkyl, halogen, alkenyl, alkynyl, phenyl, phenoxy, phenylalkyl, phenoxyalkyl, phenylmercaptoalkyl, phenylmercapto, phenylalkoxy or phenylalkylthio, it being possible for these radicals to be substituted in the phenyl moiety; … R is H, alkyl, alkyloxy, alkenyloxy, alkynyloxy, alkylthio, halogen or phenyl, which can be substituted, or … R and R together form a polymethylene chain and … R and R independently of one another are H, alkyl, alkoxyalkyl, hydroxyalkyl, alkylthioalkyl, alkenyl, substituted aminoalkyl, alkynyl, cycloalkyl, cycloalkylalkyl, each of which can be substituted in the cycloalkyl moiety, formyl, phenyl or phenylalkyl, each of which can be substituted in the phenyl moiety, or R and R together with the nitrogen atom form an unsubstituted or substituted 5- to 7-membered saturated or unsaturated heterocycle having 1 to 3 identical or different hetero atoms, … and their acid addition salts have advantageous fungicidal properties.
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公开(公告)号:HU904151D0
公开(公告)日:1990-12-28
申请号:HU415190
申请日:1990-07-10
Applicant: HOECHST AG
Inventor: GIENCKE WOLFGANG , SACHSE BURKHARD , WICKE HEINRICH
IPC: A01N43/54 , C07D401/04 , C07D401/14
Abstract: Compounds of the formula I … … in which …… R is H, alkyl, alkoxyalkyl, alkylthioalkyl, cycloalkyl, alkenyl, alkynyl, cycloalkylalkyl, substituted amino-alkyl phenyl, phenylalkyl, phenoxyalkyl, phenylmercaptoalkyl, phenoxyphenoxyalkyl, it being possible for these radicals to be substituted in the phenyl moiety, … R , R and R independently of one another are H, alkyl or phenyl which can be substituted, … R is H, alkyl, cycloalkyl, cycloalkylalkyl, haloalkyl, alkoxy, alkylthio, alkoxyalkyl, a radical R R N-, alkylthioalkyl, R R N-alkyl, halogen, alkenyl, alkynyl, phenyl, phenoxy, phenylalkyl, phenoxyalkyl, phenylmercaptoalkyl, phenylmercapto, phenylalkoxy or phenylalkylthio, it being possible for these radicals to be substituted in the phenyl moiety; … R is H, alkyl, alkyloxy, alkenyloxy, alkynyloxy, alkylthio, halogen or phenyl, which can be substituted, or … R and R together form a polymethylene chain and … R and R independently of one another are H, alkyl, alkoxyalkyl, hydroxyalkyl, alkylthioalkyl, alkenyl, substituted aminoalkyl, alkynyl, cycloalkyl, cycloalkylalkyl, each of which can be substituted in the cycloalkyl moiety, formyl, phenyl or phenylalkyl, each of which can be substituted in the phenyl moiety, or R and R together with the nitrogen atom form an unsubstituted or substituted 5- to 7-membered saturated or unsaturated heterocycle having 1 to 3 identical or different hetero atoms, … and their acid addition salts have advantageous fungicidal properties.
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公开(公告)号:AU589748B2
公开(公告)日:1989-10-19
申请号:AU6998987
申请日:1987-03-13
Applicant: HOECHST AG
Inventor: BLUME ERNST , SCHAPER WOLFGANG , EHRHARDT HEINZ , RAETHER WOLFGANG , DITTMAR WALTER , HANEL HEINZ , SACHSE BURKHARD
IPC: C07D247/00 , A01N43/50 , A01N43/653 , C07C41/00 , C07C43/18 , C07C67/00 , C07C201/00 , C07C213/00 , C07C215/42 , C07C217/48 , C07C217/74 , C07C253/00 , C07C255/54 , C07C313/00 , C07C317/12 , C07C317/14 , C07C317/18 , C07C317/20 , C07C323/22 , C07D233/56 , C07D233/60 , C07D233/61 , C07D249/08 , C07D307/38 , C07D333/00 , C07D401/12 , C07D403/12 , C07D405/06 , C07D405/12 , C07D409/12 , C07D409/14 , C07D417/12 , C07D521/00 , A61K31/41 , A61K31/495 , A61K31/445 , A61K31/425 , A61K31/44 , A61K31/505 , A61K31/415 , C07D403/08 , C07D409/06 , C07D413/12
Abstract: Compounds I I where A equals t-butyl or a large number of (substituted) aromatics; Y equals azolyl; or Y equals -X-R1 where X=oxygen or sulfur and R1 equals (cyclo)alkyl or (heterocyclic) aryl; or Y equals where R2 equals (cyclo)alkyl, acetyl or aryl; or Y equals -NR3R4 where R3/R4 is alkyl; or Y equals several nitrogen-containing heterocyclic rings; Z equals OH, alkylcarbonyloxy, hal, alkoxy or benzyloxy; and the salts thereof are effective antimycotics or fungicides. They are obtained by reaction of II II with (CH3)2 III and further reaction of the compound IV obtained from this with a nucleophile YM (M=hydrogen or a metal equivalent). The compounds I (where Z=OH) resulting from this can be acylated or alkylated, or converted into I where Z=hal.
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公开(公告)号:DD272405A5
公开(公告)日:1989-10-11
申请号:DD31846887
申请日:1987-03-10
Applicant: HOECHST AG
Inventor: SCHAPER WOLFGANG , FUSS ANDREAS , RAETHER WOLFGANG , DITTMAR WALTER , HAENEL HEINZ , GERHARDS HERMANN J , SACHSE BURKHARD
IPC: A61K31/415 , A01N43/50 , A01N43/653 , A61P25/08 , A61P31/04 , A61P31/10 , A61P33/02 , C07D233/56 , C07D233/58 , C07D233/60 , C07D233/61 , C07D247/00 , C07D249/08 , C07D335/00 , C07D405/06 , C07D409/06 , C07D521/00 , A01N43/02
Abstract: Azole compounds of the formula (I) in which A denotes CH or N, n = 1, 2 or 3, k = 1 or 2, Ar denotes a (subst.) aromatic radical or (subst.) thienyl, W denotes the atoms necessary to complete a benzene, naphthalene or thiophene ring system, X denotes a radical C(R )2 and in the case in which W denotes the atoms necessary to complete a benzene or naphthalene ring system, also denotes oxygen or sulphur, R and R denote H, halogen, (subst.) alkyl, cycloalkyl, alkoxy, alkylthio, cyano or nitro, and in the case in which W simultaneously denotes the atoms necessary to complete a benzene ring, R also denotes phenyl, phenoxy, phenylthio, phenylsulfinyl, phenylsulphonyl, benzyl, benzyloxy or hydroxyl, where the phenyl groups can be substituted or R and R together, if they are o-orientated, denote an alkylene chain; R denotes H or alkyl or two radicals R together, if they are bonded to the same C-atom, denote an alkylene chain, and their stereoisomers and salts have advantageous fungicidal, antimycotic and anticonvulsive effects.
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公开(公告)号:ZA888765B
公开(公告)日:1989-08-30
申请号:ZA888765
申请日:1988-11-23
Applicant: HOECHST AG
Inventor: EHRHARDT HEINZ , HEINZ EHRHARDT , SACHSE BURKHARD , BURKHARD SACHSE , WICKE HEINRICH , HEINRICH WICKE
IPC: A01N57/24 , C07F9/58 , C07F9/6509 , C07F9/655 , C07F9/6553 , C07F , A01N
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公开(公告)号:ZA8808765B
公开(公告)日:1989-08-30
申请号:ZA8808765
申请日:1988-11-23
Applicant: HOECHST AG
Inventor: EHRHARDT HEINZ , HEINZ EHRHARDT , SACHSE BURKHARD , BURKHARD SACHSE , WICKE HEINRICH , HEINRICH WICKE
IPC: A01N57/24 , C07F9/58 , C07F9/6509 , C07F9/655 , C07F9/6553 , C07F , A01N
CPC classification number: C07F9/650964 , A01N57/24 , C07F9/582
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公开(公告)号:HU197315B
公开(公告)日:1989-03-28
申请号:HU371086
申请日:1986-08-27
Applicant: HOECHST AG
Inventor: SCHAPPER WOLFGANG , DITTMAR WALTER , HARTZ PETER , RAETHER WOLFGANG , SACHSE BURKHARD
IPC: C07D409/06 , A01N43/50 , A01N43/653 , A61K31/41 , A61K31/415 , A61P31/00 , A61P31/04 , C07D233/60 , C07D249/08 , C07D333/00 , C07D409/08 , C07D521/00 , C07D401/06
Abstract: Azole derivatives of the formula I where A equals CH or N and R /R equals substituted or unsubstituted phenyl, biphenylyl, phenoxyphenyl, benzylphenyl, benzyloxyphenyl, naphthyl, thienyl, furyl or pyridyl and their salts and esters have outstanding antimycotic and fungicidal activity in all stereoisomeric forms. They are obtained by reaction of a compound II with a sulphur ylide of the formula III to give the compound IV which is reacted with the corresponding compound V to give I. Compound VI can also be used as a starting material and is reacted with 2 equivalents of IIIa compound IV being formed; or compound VI is first reacted with an equivalent of IIIa to give II, and II is then reacted, without working up, with the sulphur ylide IIIb (CH3)2SCH2 to give IV and this is reacted with V to give I.
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公开(公告)号:DD264607A5
公开(公告)日:1989-02-08
申请号:DD30972887
申请日:1987-12-01
Applicant: HOECHST AG
Inventor: EHRHARDT HEINZ , MILDENBERGER HILMAR , MAIER THOMAS , SCHALLER RAINER , SACHSE BURKHARD , BRAUN PETER
IPC: C07D401/04 , A01N47/38 , A61K31/415 , A61K31/4427 , A61K31/443 , A61K31/445 , A61P31/04 , C07D401/14 , C07D405/14 , C07D521/00 , A01N43/50 , A01N43/34
Abstract: Compounds of the formula (I) (I) in which n denotes a number from 2 to 6, m denotes 1 or 2, R denotes +TR CH2CH2CH2OR1, R1 denotes (substituted) alkyl, (substituted) alkenyl, C3-alkynyl, cycloalkyl, cycloalkenyl or an aromatic or heteroaromatic radical, R2 denotes H or alkyl and Y denotes H, alkyl, phenyl or halophenyl, and the metal-salt complexes thereof have advantageous fungicidal actions and are highly suitable for use in plant protection or in the industrial sector.
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公开(公告)号:HUT44408A
公开(公告)日:1988-03-28
申请号:HU248587
申请日:1987-05-29
Applicant: HOECHST AG
Inventor: GIENCKE WOLFGANG , MILDENBERGER HILMAR , HEUBACH GUENTHER , SACHSE BURKHARD , WALTERSDORFER ANNA , KNAUF WERNER , KERN MANFRED , BONIN WERNER , FUSS ANDREAS
IPC: A01N43/54 , C07D239/42 , C07D239/46 , C07D239/47 , C07D239/48
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