ABSORBANCE MEASURING EQUIPMENT
    71.
    发明专利

    公开(公告)号:JPH06160280A

    公开(公告)日:1994-06-07

    申请号:JP33511592

    申请日:1992-11-20

    Applicant: SHIMADZU CORP

    Abstract: PURPOSE:To allow measurement of absorbance over a wide range without diluting fluid sample by placing the fluid sample in a V-groove made of an inlet side transparent member and an outlet side transparent member and then measuring the quantity of measuring luminous flux transmitted through the fluid sample. CONSTITUTION:Inlet side and outlet side blocks 111, 112 constituting a translucent block 11 at a detecting section are intersected in V-shape with the interfaces 113, 114 of a liquid sample and a shade 16 is provided below the intersecting point. Before being fixed to a piping, the detecting section is placed in a standard sample having known absorbance epsilon1 in order to measure the quantity of transmitted light 11 which is then stored. The detecting section is then secured to piping and the quantity of transmitted light I is measured for the liquid sample thus calculating absorbance epsilon thereof according to a formula epsilon= epsilon1.(I1/I). In this regard, quantity of transmitted light can be measured even for a sample having high absorbance because passing distance of measuring light is shortened in the vicinity of the intersection of the blocks 111, 112 and since the fluid sample is placed in V-groove, deposition of suspensoid is retarded and cleaned off easily thus sustaining high measurement accuracy.

    MULTIPLE CONCENTRIC CIRCULAR REACTION LINE

    公开(公告)号:JPH03285172A

    公开(公告)日:1991-12-16

    申请号:JP8723990

    申请日:1990-03-30

    Applicant: SHIMADZU CORP

    Abstract: PURPOSE:To achieve the dense arrangement of reaction tubes and the simplification of driving in a moving system by mounting a turntable having reaction tube rows in concentric circular multiple arrangement, the rotary driving mechanism thereof and at least one treatment part acting on the respective reaction tube rows in a time sharing manner. CONSTITUTION:A reaction tube supply apparatus 4, a liquid distribution apparatus 8, a reagent distribution apparatus 12, a washing apparatus 16, a color forming solution distribution apparatus 18, an absorbancy measuring apparatus 20 and a waste solution sucking/reaction tube removing apparatus 22 being treatment parts are arranged around a turntable 2 having reaction tubes held in the holding holes 2a arranged in a concentric circular state. The reaction tubes 6 corresponding to different measuring items are arranged to the respective grooves of the apparatus 4 and, when the measuring item is selected, one reaction tube concerned is sent to the turntable 2 and, continuously, the respective apparatuses of the treatment parts apply predetermined operations to the corresponding reaction tube 6 by the oscillation mechanisms thereof. By this method, an apparatus having a moving type incubator in spite of a long reaction time and high treatment speed is realized and a structure can be simplified and a space can be reduced.

    REACTOR OF AUTOMATIC ANALYZER
    73.
    发明专利

    公开(公告)号:JPH03285171A

    公开(公告)日:1991-12-16

    申请号:JP8723890

    申请日:1990-03-30

    Applicant: SHIMADZU CORP

    Abstract: PURPOSE:To perform the vibratory stirring of a reaction tube to a rotary type reaction turntable by supporting the rotary shaft of other rotary system on the center-of-rotation part of a turntable having a rotary drive mechanism connected thereto and holding a plurality of reaction tubes in a rotatable manner in a state mounting an eccentric wt. on said rotary shaft. CONSTITUTION:A turntable 2 is rotated at extremely low speed by a motor 22 and an eccentric wt. 30 is rotated at about 50 Hz by a motor 32. Since the wt. 30 is supported on a vibration box 24 in a rotatable manner, a box 24 is not rotated and becomes the vibration source due to the vibration of the wt. 30 and the turntable 2 is fixed to the box 24 and both of them are integrally vibrated. The wt. 30 and the turntable 2 are provided on the almost same horizontal plane and the vertical component of vibration is suppressed. By this constitution, the vibratory stirring of a reaction tube can be performed even with respect to a rotary type reaction tube turntable and, since the rotary shaft 28 of the eccentric wt. 30 and the turntable 2 are supported in a mutually rotatable manner, it is unnecessary to rotate the motor 32 along with the turntable 2 and a structure can be simplified.

    METHOD AND APPARATUS FOR AUTOMATIC ANALYSIS

    公开(公告)号:JPH02307060A

    公开(公告)日:1990-12-20

    申请号:JP12908089

    申请日:1989-05-22

    Applicant: SHIMADZU CORP

    Abstract: PURPOSE:To increase a processing speed and to allow random accessing by allocating common analysis items to plural pieces of reaction tubes belonging to one reaction tube block integrated with plural pieces of reaction tubes. CONSTITUTION:A reaction tube supplying section is juxtaposed with plural pieces of the reaction tube blocks 1 for every analysis item arrayed with plural pieces of the reaction tubes integrated and arrayed in the form of an array and executes dispensing to the reaction tubes belonging to the reaction tube blocks 1 of the respective analysis items with the selected item of the one specimen. The reaction tube blocks 1 dispensed by each specimen dispensing are advanced by as much as one reaction tube. The specimens are successively dispensed and the reaction tube blocks 1 are transferred to an analysis section after the completion of the specimen dispensing by each reaction tube block. The specimens are sucked from specimen cups 16 of a specimen dispensing position 14 and are successively dispensed into the reaction tubes of the reaction tube blocks 1 of the prescribed items in a specimen dispensing section. While the reaction tube blocks 1 fed into the analyzing section are transferred in a transfer line 12, the common items are analyzed in the reaction tube block unit.

    CONTROL OF AUTOMATIC ANALYZER
    75.
    发明专利

    公开(公告)号:JPH02287262A

    公开(公告)日:1990-11-27

    申请号:JP10976789

    申请日:1989-04-28

    Applicant: SHIMADZU CORP

    Abstract: PURPOSE:To reduce running cost by reusing a reagent by repeating the distribu tion of a specimen and the measurement of an item to be analyzed to the re agent once distributed to a reaction tube with respect to a plurality of different specimens. CONSTITUTION:Noticing a specific reaction tube, a specimen is distributed in said reaction tube after washing and a parameter (n) showing the number of times is set to 1. After the elapse of a predetermined time from the point of time when a reagent is distributed to the reaction tube, absorbancy is mea sured. So far as abnormality is not generated, a different specimen is further distributed in order to measure the same item until the number (n) of times reaches the number R of times and 1 is added to the number (n) of times. After the elapse of a predetermined time, absorbancy is again measured. When the number (n) of distributions of the specimens reaches the set value R or the absorbancy of the specimens exceeds a definite value, said reaction tube is washed to be returned to the initial state and the next specimen is distributed and the reagent is again distributed to repeat the same operation.

    TEMPERATURE CONTROL METHOD FOR FLOW CELL

    公开(公告)号:JPH02122244A

    公开(公告)日:1990-05-09

    申请号:JP27718588

    申请日:1988-10-31

    Applicant: SHIMADZU CORP

    Inventor: TSUNASAWA YOSHIO

    Abstract: PURPOSE:To shorten the stable time of the absorbance and to shorten measuring time by matching automatically the temperature of a flow cell with the temperature of a sample itself to be measured. CONSTITUTION:In a flow cell 2, a temperature sensor 32 is provided in order to execute a temperature control, and its output is fetched to a microprocessor 22. To the flow cell 2, a thermo-module 34 is also attached, and the temperature of the flow cell 2 is controlled so as to become a prescribed temperature by the processor 22. In this state, the output of a microswitch 24 for operating a pump 10 is fetched to a suction timer 36. The processor 22 fetches the output signal of the timer 36, sets a temperature control circuit to an open loop while the timer 36 is ON, and also, operates the pump 10, and executes the temperature control of the flow cell 2 by setting the temperature control circuit to a closed loop while the time 36 is OFF.

    METHOD FOR MEASURING ACTIVITY OF ENZYME

    公开(公告)号:JPS63165737A

    公开(公告)日:1988-07-09

    申请号:JP31514086

    申请日:1986-12-26

    Applicant: SHIMADZU CORP

    Abstract: PURPOSE:To measure an enzymatic activity value with high sensitivity, by allowing the change in fluorescent intensity to correspond to the concn. of a substrate. CONSTITUTION:Enzyme to be examined is added to a definite amount of a solution containing a substrate at known concn. and the reduction quantity of fluorescent intensity after the finish of enzymatic reaction is measured by a fluorescence measuring circuit 5. Since a fluorescent substance is consumed by the reaction substance formed from the substrate by the reaction of the enzyme to be examined, the reduction quantity of fluorescence corresponds to the quantity of the formed reaction substance. Hereupon, the change quantity of the substrate due to the reaction of the enzyme to be examined is quantified as the change quantity of fluorescence intensity by a data processor 6 to measure the absolute value of an enzymatic activity value.

    PHOTOMETER
    79.
    发明专利

    公开(公告)号:JPS63158430A

    公开(公告)日:1988-07-01

    申请号:JP30726886

    申请日:1986-12-22

    Applicant: SHIMADZU CORP

    Inventor: TSUNASAWA YOSHIO

    Abstract: PURPOSE:To reduce stray light by making first and second diffraction gratings orthogonally intersect with each other and arranging portions with little stray light at each wavelength in an oblique direction relative to a dispersing direction by the second diffraction grating. CONSTITUTION:The diffraction grating 14 of a first spectroscope for dispersing light incident on an inlet slit 12 is fixed and an intermediate slit 16 extending in a dispersing direction in the imaging plane of the first spectroscope is provided. The diffraction grating 18 of a second spectroscope is fixed in a position wherein light passing the intermediate slit 16 is received in a direction wherein the dispersing direction of the diffraction grating 18 orthogonally intersects with that of the diffraction grating 14 of the first spectroscope. Portions with maximum intensities at each wavelength are arranged on the outlet side imaging plane 20 of the second spectroscope in an oblique direction relative to the dispersing direction of the diffraction grating 18 of the second spectroscope. An image in the oblique direction is detected by a one-dimensional diode array 22 provided on the imaging plane 20.

    INTEGRATING SPHERE APPARATUS
    80.
    发明专利

    公开(公告)号:JPS6388411A

    公开(公告)日:1988-04-19

    申请号:JP23406386

    申请日:1986-09-30

    Applicant: SHIMADZU CORP

    Inventor: TSUNASAWA YOSHIO

    Abstract: PURPOSE:To obtain a stability against changes in the light source or the like even with a single flux type as done with a double flux type, by dividing a part of light flux incident into an integrating sphere by a light flux splitting means such as stationary half-mirror to receive light with a silicon photocell. CONSTITUTION:A sample X is st in contact with a window provided at a position where an incident light flux of an integrating sphere I hits it directly, a light flux emitted from a spectroscope M is made to come into the sphere I and a part thereof is to fall into a silicon photocell 3. An output of the cell 3 is converted 4 into a control signal and inputted into a negative high voltage generation circuit 5, and output voltage of which 5 is applied to a diode of a photoelectric multiplier tube P to control the sensitivity of the tube P. Thus, as only one light flux is made come into the sphere I, the construction of an optical system is very simple, while light incident into the sphere I is divided 2 and monitored before the incidence thereof I thereby enabling automatic compensation for the changes in the light source 1. In addition, as the light flux being incident into the sphere I is single, restriction or the like of the geometric size of the sample X can be minimized with a larger freedom of the position of the sphere I.

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