公开(公告)号：US20210397655A1

公开(公告)日：2021-12-23

申请号：US17199345

申请日：2021-03-11

Applicant: Cleveland State University

Inventor： Wenbing Zhao

IPC: G06F16/903 ,  G06F21/44 ,  G06F16/18

Abstract: Disclosed is a system and method for processing data using blockchain technology. The system includes a memory having programmable instructions stored thereon that, when executed by a processor, cause the system to: authenticate one or more sensors in anticipation of receiving component data; receive component data, upon successful authentication; store the component data locally or to a cloud-based server and/or calculate a root value for the component data; store or embed the root value with the stored component data; condense the component data and link the condensed component data to the stored component data via the root value. The system further includes instructions to log the condensed data, including the root value, to a ledger, and to identify a tag or transaction id corresponding to the logging event for subsequent retrieval of the condensed data using the tag or transaction id.

公开(公告)号：US20210155918A1

公开(公告)日：2021-05-27

申请号：US17157130

申请日：2021-01-25

Applicant: Cleveland State University

Inventor： Michael Kalafatis ,  Joseph Wiencek

IPC: C12N9/74 ,  A61P7/02 ,  A61K38/48 ,  C12N15/79

Abstract: During the process of coagulation, prothrombin is activated to α-thrombin by prothrombinase. Key residues in the structure of prothrombin allow for modulation of the activation of prothrombin. In certain embodiments, a recombinant prothrombin with at least one point mutation or deletion is provided.

公开(公告)号：US20190328605A1

公开(公告)日：2019-10-31

申请号：US16398558

申请日：2019-04-30

Applicant: Cleveland State University

Inventor： Antonie J. van den Bogert ,  Daniel Miller ,  Ryan Doris ,  Robert Moody ,  Donald Grimes, JR.

IPC: A61H3/00 ,  A61H1/02

Abstract: An exoskeleton system is passively powered and pneumatically operated. The system may be a lower-limb system for walking gait restoration. The system may include a first linear actuator located in front of an upper leg section and a second linear actuator located behind a lower leg section.

公开(公告)号：US20190267786A1

公开(公告)日：2019-08-29

申请号：US16278452

申请日：2019-02-18

Applicant: Cleveland State University

Inventor： Wenbing Zhao

IPC: H02G7/06

Abstract: Systems and methods to perform privacy-aware computer-vision-based human activity monitoring with real-time haptic feedback. The system and method described in this disclosure employing a registration process for consenting human subjects before their activities are monitored. The registration process involves the corroboration of human motion captured in different modalities, i.e., computer-vision-based via the programmable computer-vision-based motion sensor and accelerometer-based via the wearable device. The tracked human activities are assessed in real-time and upon detection of activities that violated predefined rules, haptic feedback is delivered in real-time to the tracked human subject via the wearable device worn by the caregiver.

公开(公告)号：US20190107532A1

公开(公告)日：2019-04-11

申请号：US16157727

申请日：2018-10-11

Applicant: Cleveland State University

Inventor： Moo-Yeal Lee ,  Xue-Long Sun

IPC: G01N33/50

Abstract: A multiplexed method of monitoring immune-cell responses to different ligands using a micropillar/microwell plate platform is disclosed. The method may include dispensing immune cells onto at least one micropillar chip and inserting the at least one micropillar into at least one microwell on a microwell chip, in which the at least one microwell contains at least one test compound. The method may also include immobilizing antibodies onto at least one micropillar on a micropillar chip and inserting the at least one micropillar into at least one microwell on a microwell chip, in which the at least one microwell contains a test compound. The method may also include treating the micropillar chip with at least one reactive polymer.

公开(公告)号：US10173253B2

公开(公告)日：2019-01-08

申请号：US14907072

申请日：2014-07-23

Applicant: CLEVELAND STATE UNIVERSITY

Inventor： Taysir H. Nayfeh ,  Anita M. Wiederholt

IPC: H01L39/24 ,  B21C23/00 ,  B21C37/04 ,  B22F3/00 ,  B22F3/16 ,  B22F3/20 ,  B22F7/06 ,  B30B11/26 ,  C22C47/14 ,  C22C49/02 ,  C22C49/04 ,  H01B1/02 ,  B30B11/00 ,  B22D17/04 ,  B22D19/02

Abstract: When forming ultra-conductive wire, multi-walled carbon nanotubes (MWCNTs) are dispersed and de-agglomerated in hot metal. The MWCNTs are dispersed in a precursor matrix via mixing and sintering to form precursor material, which is hot-extruded multiple rounds at a predetermined temperature to form a nano-composite material. The nano-composite material is inserted into a metal bar to form a nano-composite billet (306), which is subjected to multiple rounds of hot extrusion to form an ultra-conductive material. The ultra-conductive material is subjected to one or more rounds of hot wire drawing to form an ultra-conductive wire comprising a nano-composite filament.

公开(公告)号：US20180339196A1

公开(公告)日：2018-11-29

申请号：US15990937

申请日：2018-05-29

Applicant: Cleveland State University

Inventor： Hanz Richter

IPC: A63B24/00 ,  A63B22/00 ,  A63B21/005

Abstract: An exercise system includes a motor, a chain having a first end connected to the motor, and a handle or seat connected to a second end of the chain, and a control system to obtain variable mechanical resistance with continuous variation. The system may enable unrestricted type of resistance, including adjustable ratios of concentric/eccentric power.

公开(公告)号：US20180296422A1

公开(公告)日：2018-10-18

申请号：US15485962

申请日：2017-04-12

Applicant: Cleveland State University

Inventor： Jerzy T. Sawicki ,  Curt A. Laubscher ,  Ryan J. Farris ,  Steven J-S Etheridge

IPC: A61H3/00 ,  F16H19/00

Abstract: An actuating device for orthosis including a housing, a motor, a transmission disposed in the housing, and an actuating arm. The transmission is operatively connected to the motor such that the motor provides power to the transmission. The transmission includes a first stage, a second stage, and a third stage. The first stage has a first sprocket, a second sprocket, and a first drive belt tensioned between the first sprocket and the second sprocket. The first sprocket is attached to a shaft of the motor. The second stage has a third sprocket, a fourth sprocket, and a second drive belt tensioned by the third sprocket and the fourth sprocket. The third sprocket is attached to the second sprocket of the first stage. The third stage has a fifth sprocket, a sixth sprocket, and a third drive belt tensioned by the fifth sprocket and the sixth sprocket. The fifth sprocket is attached to the fourth sprocket of the second stage. The transmission additionally includes a first shaft and a second shaft. The second sprocket, the third sprocket, and the sixth sprocket are attached to the first shaft, and the fourth sprocket and the fifth sprocket are attached to the second shaft. The actuating arm is operatively connected to the sixth sprocket of the third stage of the transmission such that the power provided to the transmission by the motor causes the actuating arm to provide an output torque.

公开(公告)号：US20170176981A9

公开(公告)日：2017-06-22

申请号：US14723709

申请日：2015-05-28

Applicant: Cleveland State University

Inventor： Zhiqiang Gao

IPC: G05B19/416 ,  G05B15/02

CPC classification number: G05B13/024 ,  G05B5/01 ,  G05B11/42 ,  G05B13/042 ,  G05B15/02 ,  G05B19/416 ,  G05B2219/33347

Abstract: Controller scaling and parameterization are described. Techniques that can be improved by employing the scaling and parameterization include, but are not limited to, controller design, tuning and optimization. The scaling and parameterization methods described here apply to transfer function based controllers, including PID controllers. The parameterization methods also applies to state feedback and state observer based controllers, as well as linear active disturbance rejection controllers. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the application. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.

公开(公告)号：US20150147771A1

公开(公告)日：2015-05-28

申请号：US14547744

申请日：2014-11-19

Applicant: Cleveland State University

Inventor： Andrew H. Resnick ,  Ulrich Hopfer ,  Christian A. Zorman

IPC: G01N33/50

CPC classification number: G01N33/4833 ,  A61B5/00

Abstract: A cell layer measurement device includes a first zone, a second zone, and a porous membrane between the first and second zones. A tissue sample includes the cell layer on the porous membrane. A fluid is on at least a first side of the tissue. A fluid inflow line and fluid outflow line are on at least a first side of the tissue. At least one electrode measures a property of the fluid. A property of the cell layer is determined based on the measured property of the fluid.

Abstract translation: 细胞层测量装置包括在第一和第二区之间的第一区，第二区和多孔膜。 组织样本包括多孔膜上的细胞层。 流体在组织的至少第一侧上。 流体流入管线和流体流出管线在组织的至少第一侧上。 至少一个电极测量流体的性质。 基于测量的流体性质确定电池层的性质。